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Compile Data Set for Download or QSAR

Found 276 hits Enz. Inhib. hit(s) with Target = 'GABA receptor alpha-1/beta-2/gamma-2 subunit'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50055963
PNG
(1-[(3R,5R,10S,13S,17S)-3-(4-Acetyl-phenylethynyl)-...)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccc(cc1)C(C)=O
Show InChI InChI=1S/C31H40O3/c1-20(32)23-7-5-22(6-8-23)13-16-31(34)18-17-29(3)24(19-31)9-10-25-27-12-11-26(21(2)33)30(27,4)15-14-28(25)29/h5-8,24-28,34H,9-12,14-15,17-19H2,1-4H3/t24-,25+,26-,27+,28+,29+,30-,31-/m1/s1
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n/an/an/an/a 6.60n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454531
PNG
(CHEMBL3138433)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@@H]4[C@H]3CC[C@]12C)C#Cc1ccc(cc1)C(C)=O
Show InChI InChI=1S/C30H38O3/c1-19(31)22-6-4-21(5-7-22)12-16-30(33)17-14-24-23(18-30)8-9-26-25(24)13-15-29(3)27(20(2)32)10-11-28(26)29/h4-7,23-28,33H,8-11,13-15,17-18H2,1-3H3/t23-,24+,25-,26-,27-,28+,29-,30-/m1/s1
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n/an/an/an/a 8.20n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50065229
PNG
(4-Ethyl-6,7-dimethoxy-9H-beta-carboline-3-carboxyl...)
Show SMILES CCc1c([nH]cc2nc3cc(OC)c(OC)cc3c12)C(=O)OC
Show InChI InChI=1S/C17H18N2O4/c1-5-9-15-10-6-13(21-2)14(22-3)7-11(10)19-12(15)8-18-16(9)17(20)23-4/h6-8,18H,5H2,1-4H3
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n/an/an/an/a 9n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha1beta2gamma2 GABA receptor expressed in Xenopus laevis oocytes


Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454527
PNG
(CHEMBL3138291)
Show SMILES CN(C)c1ccc(cc1)C#C[C@@]1(O)CC[C@@]2(C)[C@H](CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC[C@H]23)C1
Show InChI InChI=1S/C31H43NO2/c1-21(33)26-12-13-27-25-11-8-23-20-31(34,17-14-22-6-9-24(10-7-22)32(4)5)19-18-29(23,2)28(25)15-16-30(26,27)3/h6-7,9-10,23,25-28,34H,8,11-13,15-16,18-20H2,1-5H3/t23-,25+,26-,27+,28+,29+,30-,31-/m1/s1
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n/an/an/an/a 18n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454526
PNG
(CHEMBL3138293)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccc(C=O)cc1
Show InChI InChI=1S/C30H38O3/c1-20(32)25-10-11-26-24-9-8-23-18-30(33,15-12-21-4-6-22(19-31)7-5-21)17-16-28(23,2)27(24)13-14-29(25,26)3/h4-7,19,23-27,33H,8-11,13-14,16-18H2,1-3H3/t23-,24+,25-,26+,27+,28+,29-,30-/m1/s1
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n/an/an/an/a 31n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50215531
PNG
(2-chloro-alpha-[[(4-chlorophenyl)amino]methylene]-...)
Show SMILES CC(C)NC(=O)C(C=Nc1ccc(Cl)cc1)C(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H18Cl2N2O2/c1-12(2)23-19(25)16(11-22-14-9-7-13(20)8-10-14)18(24)15-5-3-4-6-17(15)21/h3-12,16H,1-2H3,(H,23,25)
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n/an/an/an/a 34n/an/an/an/a



University of California-Irvine

Curated by ChEMBL


Assay Description
Activity at human GABAA alpha-1-beta-2-gamma-2L expressed in Xenopus oocytes assessed as potentiation of GABA currents


J Med Chem 50: 3369-79 (2007)


Article DOI: 10.1021/jm070083v
BindingDB Entry DOI: 10.7270/Q2K35TB7
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50000766
PNG
(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1
Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
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n/an/an/an/a 85n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha1beta2gamma2 GABA receptor expressed in Xenopus laevis oocytes


Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50055919
PNG
(1-((3R,5S,10S,13S,17S)-3-Azidomethyl-3-hydroxy-10,...)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@](O)(CN=[N+]=[N-])CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C22H35N3O2/c1-14(26)17-6-7-18-16-5-4-15-12-22(27,13-24-25-23)11-10-20(15,2)19(16)8-9-21(17,18)3/h15-19,27H,4-13H2,1-3H3/t15-,16-,17+,18-,19-,20-,21+,22+/m0/s1
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n/an/an/an/a 150n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 61-72 (1997)


Article DOI: 10.1021/jm960021x
BindingDB Entry DOI: 10.7270/Q2M0463J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50191342
PNG
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/m0/s1
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n/an/an/an/a 160n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 61-72 (1997)


Article DOI: 10.1021/jm960021x
BindingDB Entry DOI: 10.7270/Q2M0463J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50207314
PNG
(CHEMBL3971200)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(F)cc1
Show InChI InChI=1S/C18H18FN3O/c1-12-4-9-16-20-18(13-5-7-14(19)8-6-13)15(22(16)11-12)10-17(23)21(2)3/h4-9,11H,10H2,1-3H3
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n/an/an/an/a 238n/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...


Eur J Med Chem 124: 456-467 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.059
BindingDB Entry DOI: 10.7270/Q22B911Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM26266
PNG
(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3
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n/an/an/an/a 240n/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...


Eur J Med Chem 124: 456-467 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.059
BindingDB Entry DOI: 10.7270/Q22B911Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50369240
PNG
(GANAXOLONE)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16-,17+,18-,19-,20+,21-,22+/m0/s1
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n/an/an/an/a 260n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 61-72 (1997)


Article DOI: 10.1021/jm960021x
BindingDB Entry DOI: 10.7270/Q2M0463J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM86521
PNG
(CAS_5719 | NSC_5719 | Zaleplon)
Show SMILES CCN(C(C)=O)c1cccc(c1)-c1ccnc2c(cnn12)C#N
Show InChI InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3
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n/an/an/an/a 290n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Modulation of human GABA-A alpha1beta2gamma2 expressed in xenopus oocytes assessed as potentiation of GABA-evoked chloride currents


J Med Chem 56: 593-624 (2013)


Article DOI: 10.1021/jm3011433
BindingDB Entry DOI: 10.7270/Q23B61GZ
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50055953
PNG
(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccccc1O
Show InChI InChI=1S/C29H38O3/c1-19(30)23-10-11-24-22-9-8-21-18-29(32,15-12-20-6-4-5-7-26(20)31)17-16-27(21,2)25(22)13-14-28(23,24)3/h4-7,21-25,31-32H,8-11,13-14,16-18H2,1-3H3/t21-,22+,23-,24+,25+,27+,28-,29-/m1/s1
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n/an/an/an/a 340n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50332375
PNG
(4-Amino-8-(5-(azetidine-1-carbonyl)pyridin-3-yl)-N...)
Show SMILES CCCNC(=O)c1nnc2c(cccc2c1N)-c1cncc(c1)C(=O)N1CCC1
Show InChI InChI=1S/C21H22N6O2/c1-2-7-24-20(28)19-17(22)16-6-3-5-15(18(16)25-26-19)13-10-14(12-23-11-13)21(29)27-8-4-9-27/h3,5-6,10-12H,2,4,7-9H2,1H3,(H2,22,25)(H,24,28)
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n/an/an/an/a 389n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha1beta2gamma2 GABA receptor expressed in Xenopus laevis oocytes


Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454499
PNG
(CHEMBL3137990)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C(F)(F)F
Show InChI InChI=1S/C22H33F3O2/c1-13(26)16-6-7-17-15-5-4-14-12-21(27,22(23,24)25)11-10-19(14,2)18(15)8-9-20(16,17)3/h14-18,27H,4-12H2,1-3H3/t14-,15-,16+,17-,18-,19-,20+,21+/m0/s1
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n/an/an/an/a 390n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 61-72 (1997)


Article DOI: 10.1021/jm960021x
BindingDB Entry DOI: 10.7270/Q2M0463J
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50207312
PNG
(CHEMBL3954951)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(F)cn12)-c1ccc(F)cc1
Show InChI InChI=1S/C17H15F2N3O/c1-21(2)16(23)9-14-17(11-3-5-12(18)6-4-11)20-15-8-7-13(19)10-22(14)15/h3-8,10H,9H2,1-2H3
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n/an/an/an/a 408n/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...


Eur J Med Chem 124: 456-467 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.059
BindingDB Entry DOI: 10.7270/Q22B911Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409548
PNG
(CHEMBL29790)
Show SMILES Cc1cccc(c1O)C(C)(C)C
Show InChI InChI=1S/C11H16O/c1-8-6-5-7-9(10(8)12)11(2,3)4/h5-7,12H,1-4H3
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n/an/an/an/a 501n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052792
PNG
(CHEBI:7035 | MUSCIMOL | Muscimol)
Show SMILES NCc1cc(O)no1
Show InChI InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
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n/an/an/an/a 537n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052792
PNG
(CHEBI:7035 | MUSCIMOL | Muscimol)
Show SMILES NCc1cc(O)no1
Show InChI InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
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n/an/an/an/a 540n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454529
PNG
(CHEMBL3138315)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccc(N)cc1
Show InChI InChI=1S/C29H39NO2/c1-19(31)24-10-11-25-23-9-6-21-18-29(32,15-12-20-4-7-22(30)8-5-20)17-16-27(21,2)26(23)13-14-28(24,25)3/h4-5,7-8,21,23-26,32H,6,9-11,13-14,16-18,30H2,1-3H3/t21-,23+,24-,25+,26+,27+,28-,29-/m1/s1
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n/an/an/an/a>1.00E+3n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50454528
PNG
(CHEMBL3138292)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccc(O)cc1
Show InChI InChI=1S/C29H38O3/c1-19(30)24-10-11-25-23-9-6-21-18-29(32,15-12-20-4-7-22(31)8-5-20)17-16-27(21,2)26(23)13-14-28(24,25)3/h4-5,7-8,21,23-26,31-32H,6,9-11,13-14,16-18H2,1-3H3/t21-,23+,24-,25+,26+,27+,28-,29-/m1/s1
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n/an/an/an/a>1.00E+3n/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50125936
PNG
(3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...)
Show InChI InChI=1S/C16H18N4O2/c1-12(13-6-4-3-5-7-13)20-11-17-10-14(20)15(21)22-9-8-16(2)18-19-16/h3-7,10-12H,8-9H2,1-2H3/t12-/m1/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



Massachusetts General Hospital

Curated by ChEMBL


Assay Description
In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brain


J Med Chem 46: 1257-65 (2003)


Article DOI: 10.1021/jm020465v
BindingDB Entry DOI: 10.7270/Q24J0FVZ
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50125935
PNG
((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...)
Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1
Show InChI InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



Massachusetts General Hospital

Curated by ChEMBL


Assay Description
Ability to enhance currents from alpha-1-beta-2-gamma-2L-subunit of GABA receptor elicited by low concentrations of GABA


J Med Chem 46: 1257-65 (2003)


Article DOI: 10.1021/jm020465v
BindingDB Entry DOI: 10.7270/Q24J0FVZ
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50207313
PNG
(CHEMBL3962969)
Show SMILES CN(C)C(=O)Cc1c(nc2ccc(F)cn12)-c1ccc(C)cc1
Show InChI InChI=1S/C18H18FN3O/c1-12-4-6-13(7-5-12)18-15(10-17(23)21(2)3)22-11-14(19)8-9-16(22)20-18/h4-9,11H,10H2,1-3H3
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n/an/an/an/a 1.27E+3n/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human recombinant GABA-A receptor alpha1beta2gamma2 expressed in HEK293 cells assessed as potentiation of of GABA i...


Eur J Med Chem 124: 456-467 (2016)


Article DOI: 10.1016/j.ejmech.2016.08.059
BindingDB Entry DOI: 10.7270/Q22B911Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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n/an/an/an/a 1.78E+3n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50120861
PNG
(CHEMBL3616638)
Show SMILES CCCc1cc(NC(C)=O)c(O)c(c1)-c1ccc(OCC)c(CCC)c1
Show InChI InChI=1S/C22H29NO3/c1-5-8-16-12-19(22(25)20(13-16)23-15(4)24)17-10-11-21(26-7-3)18(14-17)9-6-2/h10-14,25H,5-9H2,1-4H3,(H,23,24)
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n/an/an/an/a 1.80E+3n/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Allosteric modulation of GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induc...


Bioorg Med Chem 23: 6757-62 (2015)


Article DOI: 10.1016/j.bmc.2015.08.034
BindingDB Entry DOI: 10.7270/Q2WQ05KM
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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n/an/an/an/a 1.80E+3n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50058046
PNG
(CHEMBL526 | PROPOFOL | propofol)
Show SMILES CC(C)c1cccc(C(C)C)c1O
Show InChI InChI=1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50125936
PNG
(3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...)
Show InChI InChI=1S/C16H18N4O2/c1-12(13-6-4-3-5-7-13)20-11-17-10-14(20)15(21)22-9-8-16(2)18-19-16/h3-7,10-12H,8-9H2,1-2H3/t12-/m1/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



Massachusetts General Hospital

Curated by ChEMBL


Assay Description
Direct activation of Gamma-aminobutyric acid A receptor in the absence of GABA


J Med Chem 46: 1257-65 (2003)


Article DOI: 10.1021/jm020465v
BindingDB Entry DOI: 10.7270/Q24J0FVZ
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50125935
PNG
((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...)
Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1
Show InChI InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



Massachusetts General Hospital

Curated by ChEMBL


Assay Description
In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brain


J Med Chem 46: 1257-65 (2003)


Article DOI: 10.1021/jm020465v
BindingDB Entry DOI: 10.7270/Q24J0FVZ
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409537
PNG
(CHEMBL109956)
Show SMILES CC(C)Cc1cccc(CC(C)C)c1O
Show InChI InChI=1S/C14H22O/c1-10(2)8-12-6-5-7-13(14(12)15)9-11(3)4/h5-7,10-11,15H,8-9H2,1-4H3
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n/an/an/an/a 2.51E+3n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052799
PNG
(CHEMBL3322882)
Show SMILES NC1=NCC(CC1)C(O)=O
Show InChI InChI=1S/C6H10N2O2/c7-5-2-1-4(3-8-5)6(9)10/h4H,1-3H2,(H2,7,8)(H,9,10)
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n/an/an/an/a 2.60E+3n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052799
PNG
(CHEMBL3322882)
Show SMILES NC1=NCC(CC1)C(O)=O
Show InChI InChI=1S/C6H10N2O2/c7-5-2-1-4(3-8-5)6(9)10/h4H,1-3H2,(H2,7,8)(H,9,10)
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n/an/an/an/a 2.63E+3n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50129952
PNG
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)
Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1
Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H
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n/an/an/an/a 3.60E+3n/an/an/an/a



University of Sydney

Curated by ChEMBL


Assay Description
Effective concentration against human recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Xenopus oocytes


Bioorg Med Chem Lett 13: 2281-4 (2003)


Article DOI: 10.1016/s0960-894x(03)00434-7
BindingDB Entry DOI: 10.7270/Q2V987F7
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50350149
PNG
(CHEMBL1814312)
Show SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O
Show InChI InChI=1S/C21H23NO3/c1-5-7-15-11-18(21(24)19(12-15)22-14(3)23)16-9-10-20(25-4)17(13-16)8-6-2/h5-6,9-13,24H,1-2,7-8H2,3-4H3,(H,22,23)
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n/an/an/an/a 5.30E+3n/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Allosteric modulation of GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induc...


Bioorg Med Chem 23: 6757-62 (2015)


Article DOI: 10.1016/j.bmc.2015.08.034
BindingDB Entry DOI: 10.7270/Q2WQ05KM
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50373059
PNG
(CHEMBL429317)
Show SMILES Cc1cc(on1)C(C=Nc1ccc(Cl)cc1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11,17H,1H3,(H,23,25)
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n/an/an/an/a 6.30E+3n/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Activation of human GABAA alpha-2-beta-3-gamma-2L receptor expressed in Xenopus oocytes assessed as modulation of GABA-induced current by two-electro...


Proc Natl Acad Sci USA 104: 8059-64 (2007)


Article DOI: 10.1073/pnas.0701321104
BindingDB Entry DOI: 10.7270/Q2NS0VS3
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50120861
PNG
(CHEMBL3616638)
Show SMILES CCCc1cc(NC(C)=O)c(O)c(c1)-c1ccc(OCC)c(CCC)c1
Show InChI InChI=1S/C22H29NO3/c1-5-8-16-12-19(22(25)20(13-16)23-15(4)24)17-10-11-21(26-7-3)18(14-17)9-6-2/h10-14,25H,5-9H2,1-4H3,(H,23,24)
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n/an/an/an/a 6.90E+3n/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Partial agonist activity at GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as induction of chloride c...


Bioorg Med Chem 23: 6757-62 (2015)


Article DOI: 10.1016/j.bmc.2015.08.034
BindingDB Entry DOI: 10.7270/Q2WQ05KM
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50064424
PNG
(4-Iodo-2,6-diisopropyl-phenol | 4-Iodo-2,6-diisopr...)
Show SMILES CC(C)c1cc(I)cc(C(C)C)c1O
Show InChI InChI=1S/C12H17IO/c1-7(2)10-5-9(13)6-11(8(3)4)12(10)14/h5-8,14H,1-4H3
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n/an/an/an/a 1.00E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50058046
PNG
(CHEMBL526 | PROPOFOL | propofol)
Show SMILES CC(C)c1cccc(C(C)C)c1O
Show InChI InChI=1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
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n/an/an/an/a 1.00E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50032955
PNG
(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)
Show SMILES OC(=O)C1=CCNCC1
Show InChI InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
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n/an/an/an/a 1.10E+4n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50032955
PNG
(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)
Show SMILES OC(=O)C1=CCNCC1
Show InChI InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
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n/an/an/an/a 1.12E+4n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409540
PNG
(CHEMBL30014)
Show SMILES CCc1cccc(CC)c1O
Show InChI InChI=1S/C10H14O/c1-3-8-6-5-7-9(4-2)10(8)11/h5-7,11H,3-4H2,1-2H3
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n/an/an/an/a 1.26E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052801
PNG
(CHEMBL3322886)
Show SMILES NC1=NCC(CN1)C(O)=O
Show InChI InChI=1S/C5H9N3O2/c6-5-7-1-3(2-8-5)4(9)10/h3H,1-2H2,(H,9,10)(H3,6,7,8)
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n/an/an/an/a 1.40E+4n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50052801
PNG
(CHEMBL3322886)
Show SMILES NC1=NCC(CN1)C(O)=O
Show InChI InChI=1S/C5H9N3O2/c6-5-7-1-3(2-8-5)4(9)10/h3H,1-2H2,(H,9,10)(H3,6,7,8)
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n/an/an/an/a 1.41E+4n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assay


Eur J Med Chem 84: 404-16 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.039
BindingDB Entry DOI: 10.7270/Q2QV3P4Z
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50120863
PNG
(CHEMBL3616640)
Show SMILES CCCc1cc(N)c(O)c(c1)-c1ccc(OCC)c(CCC)c1
Show InChI InChI=1S/C20H27NO2/c1-4-7-14-11-17(20(22)18(21)12-14)15-9-10-19(23-6-3)16(13-15)8-5-2/h9-13,22H,4-8,21H2,1-3H3
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n/an/an/an/a 1.44E+4n/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Allosteric modulation of GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induc...


Bioorg Med Chem 23: 6757-62 (2015)


Article DOI: 10.1016/j.bmc.2015.08.034
BindingDB Entry DOI: 10.7270/Q2WQ05KM
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50120859
PNG
(CHEMBL3616636)
Show SMILES CCCc1ccc(OC)c(c1)-c1cc(N)c(O)c(CCC)c1
Show InChI InChI=1S/C19H25NO2/c1-4-6-13-8-9-18(22-3)16(10-13)15-11-14(7-5-2)19(21)17(20)12-15/h8-12,21H,4-7,20H2,1-3H3
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n/an/an/an/a 1.58E+4n/an/an/an/a



University of Graz

Curated by ChEMBL


Assay Description
Allosteric modulation of GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induc...


Bioorg Med Chem 23: 6757-62 (2015)


Article DOI: 10.1016/j.bmc.2015.08.034
BindingDB Entry DOI: 10.7270/Q2WQ05KM
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409539
PNG
(CHEMBL111084)
Show SMILES CCc1cccc(CC)c1N=C=S
Show InChI InChI=1S/C11H13NS/c1-3-9-6-5-7-10(4-2)11(9)12-8-13/h5-7H,3-4H2,1-2H3
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n/an/an/an/a 1.58E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409537
PNG
(CHEMBL109956)
Show SMILES CC(C)Cc1cccc(CC(C)C)c1O
Show InChI InChI=1S/C14H22O/c1-10(2)8-12-6-5-7-13(14(12)15)9-11(3)4/h5-7,10-11,15H,8-9H2,1-4H3
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n/an/an/an/a 2.00E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
GABA receptor alpha-1/beta-2/gamma-2 subunit


(Homo sapiens (Human))
BDBM50409543
PNG
(CHEMBL111762)
Show SMILES CCc1cccc(CC)c1Br
Show InChI InChI=1S/C10H13Br/c1-3-8-6-5-7-9(4-2)10(8)11/h5-7H,3-4H2,1-2H3
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Article
PubMed
n/an/an/an/a 2.00E+4n/an/an/an/a



University of Chicago Medical Center

Curated by ChEMBL


Assay Description
Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2


J Med Chem 45: 3210-21 (2002)


Article DOI: 10.1021/jm010461a
BindingDB Entry DOI: 10.7270/Q2FN17DV
More data for this
Ligand-Target Pair
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