Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as glycine-induced increase in current response a...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
Affinity DataEC50: 454nMAssay Description:Positive allosteric modulation of human GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
Affinity DataEC50: 454nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as glycine-induced increase in current response a...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-3(Mus musculus)
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataEC50: 490nMAssay Description:Positive allosteric modulation of mouse GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Positive allosteric modulation of recombinant human glycine receptor alpha3 expressed in CHOK1 cells at -60 mV holding potential by whole cell patch-...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3 expressed in HEK293 cells assessed as potentiation of glycine-induced current flux by electrophysi...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
Affinity DataIC50: 3.39E+4nMAssay Description:Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMAssay Description:Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to human GlyRalpha3cryst by SPR methodMore data for this Ligand-Target Pair
Affinity DataKd: 70nMAssay Description:Binding affinity to human GlyRalpha3cryst by SPR methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Modulation of recombinant GlyR-alpha3 (unknown origin) expressed in HEK293 cells assessed as inhibition of glycine-induced current by automated plana...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair