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Found 599 Enz. Inhib. hit(s) with Target = 'Large envelope protein'
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289776(US10093673, Compound 5.2)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289769(US10093673, Compound 1.1)
Affinity DataEC50:  0.100nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289772(US10093673, Compound 3.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289774(US10093673, Compound 4.1)
Affinity DataEC50:  0.300nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289779(US10093673, Compound 7.1)
Affinity DataEC50:  0.800nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519994((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  1nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289781(US10093673, Compound 8.1)
Affinity DataEC50:  1nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540695(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  3nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540719((E)-3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-...)
Affinity DataEC50:  3nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520012(US11142527, Example 44)
Affinity DataEC50:  3.60nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520067(US11142527, Example 134)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540689(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540693(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540694(3-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519990(3-((R)-4-(4-((S)-7-(((R)-6-(2-chloro-4-fluoropheny...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519996(1-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540700(US11261190, Example 24)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540707((R)-methyl 6-(((S)-2-(4-acetylphenyl)-3-oxohexahyd...)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540732(US11261190, Example 60B)
Affinity DataEC50:  4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520042((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  4.20nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519991(1-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540733(US11261190, Example 61B)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540691(2-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540696(3-(2-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540698(US11261190, Example 22)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289777(US10093673, Compound 6.1 | US10093673, Compound 6....)
Affinity DataEC50:  5nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540701(US11261190, Example 25)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540704(US11261190, Example 28)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540712(3-(3-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520009(US11142527, Example 41)
Affinity DataEC50:  5.10nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520029(US11142527, Example 76)
Affinity DataEC50:  5.40nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520000(1-(3-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  6nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519987(2-(4-(2-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5...)
Affinity DataEC50:  6nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540708(US11261190, Example 32)
Affinity DataEC50:  6nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540705(US11261190, Example 29)
Affinity DataEC50:  6nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM519997(1-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  6nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM289775(US10093673, Compound 5.1)
Affinity DataEC50:  6nMAssay Description:HepG2-Clone42 cells were seeded in into black clear-bottom 96-well plates at a concentration of 6.0×104 cells/well. 24 hours post-seeding, the cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520045((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  6.20nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520014(US11142527, Example 48)
Affinity DataEC50:  6.30nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520046((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  6.5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520068(US11142527, Example 135)
Affinity DataEC50:  6.5nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520007(US11142527, Example 39)
Affinity DataEC50:  6.60nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520065(3-(4′-((S)-7-(((R)-6-(2-chloro-4-fluoropheny...)
Affinity DataEC50:  6.70nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520047((4R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((8aS)-...)
Affinity DataEC50:  6.80nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520001(4′-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-...)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520002(4′-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-...)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM520003(4′-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-...)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540703(US11261190, Example 27)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540690(2-(4-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Novartis

US Patent
LigandPNGBDBM540699(US11261190, Example 23)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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