Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDR1 (Human immunodeficiency virus) | BDBM8125![]() ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...) | PDB MMDB B.MOAD GoogleScholar | Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MDR1 (Human immunodeficiency virus) | BDBM104102![]() ((2S,3S)-2-(Acetylamino)-N-[(1S,2R)-3-[(6-benzothia...) | PDB MMDB B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MDR1 (Human immunodeficiency virus) | BDBM104107![]() ((2S,3S)-2-(Acetylamino)-N-[(1S,2R)-2-hydroxy-3-[[(...) | PDB MMDB B.MOAD GoogleScholar | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 15.1 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MDR1 (Human immunodeficiency virus) | BDBM577![]() ((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...) | PDB MMDB B.MOAD GoogleScholar | Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 15.6 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MDR1 (Human immunodeficiency virus) | BDBM104108![]() (N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...) | PDB MMDB B.MOAD GoogleScholar | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 86.9 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MDR1 (Human immunodeficiency virus) | BDBM104103![]() (N-[(1S,2R)-3-[(6-Benzothiazolylsulfonyl)(cyclohexy...) | PDB MMDB B.MOAD GoogleScholar | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 99.1 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair |