Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180647![]() (CHEMBL3818777) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180648![]() (CHEMBL3818150) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180643![]() (CHEMBL3818311) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180645![]() (CHEMBL3817951) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180649![]() (CHEMBL3818851) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22000![]() (7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180650![]() (CHEMBL3817902) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180641![]() (CHEMBL3818095) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180638![]() (CHEMBL3818980) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180639![]() (CHEMBL3818923) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180646![]() (CHEMBL3819279) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180642![]() (CHEMBL3818476) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 420 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180644![]() (CHEMBL3818991) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180640![]() (CHEMBL3819278) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 520 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180651![]() (CHEMBL3819158) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50180637![]() (CHEMBL3818005) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Medchemcomm 7: 900-905 (2016) Article DOI: 10.1039/c5md00579e BindingDB Entry DOI: 10.7270/Q2GB260N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21995![]() (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0900 | -56.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22000![]() (7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0955 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22000![]() (7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.100 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22001![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22001![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.280 | -54.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22009![]() (5-{[(1R,3R)-3-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.290 | -53.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22001![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.302 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21992![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 0.310 | -53.7 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21986![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21986![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.330 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21986![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21986![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.331 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22002![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.350 | -53.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22002![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.355 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22010![]() (5-{[(1R,3S)-3-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.420 | -53.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21996![]() (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.430 | -52.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22002![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21994![]() (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.520 | -52.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22011![]() (5-{[(1S,3R,4S)-3,4-dihydroxycyclopentyl]sulfanyl}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.680 | -51.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22000![]() (7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22025![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.790 | -51.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21987![]() (6-[(6-fluoroquinolin-4-yl)methyl]-5-{[(3R)-3-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.810 | -51.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22014![]() (5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 1.10 | -50.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21998![]() (6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | -50.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21997![]() (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | -49.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22004![]() (3-methyl-1-(2-methylpropyl)-5-(propan-2-ylsulfanyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 2.20 | -48.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22008![]() (5-{[(1R,2R)-2-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 2.70 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM21993![]() (6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.20 | -48.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22006![]() (5-(cyclopentylsulfanyl)-3-methyl-1-(2-methylpropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.20 | -48.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22025![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21985![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM50416571![]() (CHEMBL1221551) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-... | Nat Chem Biol 1: 371-6 (2005) Article DOI: 10.1038/nchembio744 BindingDB Entry DOI: 10.7270/Q2MC9063 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22020![]() (5-[(3-hydroxy-3-methylazetidin-1-yl)carbonyl]-3-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.5 | -47.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate Transporter 1 (Homo sapiens (Human)) | BDBM22024![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(iso...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 3.90 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair |
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