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Compile Data Set for Download or QSAR

Found 103 hits Enz. Inhib. hit(s) with Target = 'N-arachidonyl glycine receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50056486
PNG
(((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic a...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC(O)=O
Show InChI InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-
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n/an/an/an/a 20n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant full length human GPR18 expressed in CHO cells assessed as forskolin-stimulated cAMP accumulation after 10 mins by en...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50056486
PNG
(((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic a...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC(O)=O
Show InChI InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-
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n/an/an/an/a 44n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in HEK293 cells assessed as induction of p44/42 MAPK phosphorylation after 5 mins by Western bl...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM60994
PNG
((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Show SMILES CCCCCc1cc(O)c2[C@@H]3C=C(C)CC[C@H]3C(C)(C)Oc2c1
Show InChI InChI=1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1
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n/an/an/an/a 4.61E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human GPR18 transfected in CHO cells after 90 mins by beta-arrestin translocation assay


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449589
PNG
(CHEMBL4173561)
Show SMILES Clc1ccc(COc2cccc(\C=C3/SC(=S)NC3=O)c2)cc1
Show InChI InChI=1S/C17H12ClNO2S2/c18-13-6-4-11(5-7-13)10-21-14-3-1-2-12(8-14)9-15-16(20)19-17(22)23-15/h1-9H,10H2,(H,19,20,22)/b15-9-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449578
PNG
(CHEMBL4159298)
Show SMILES Clc1ccc(OCCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C26H29ClN2O3S/c27-21-10-12-22(13-11-21)31-15-4-2-1-3-5-16-32-23-9-6-8-20(18-23)19-24-25(30)29-14-7-17-33-26(29)28-24/h6,8-13,18-19H,1-5,7,14-17H2/b24-19-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449587
PNG
(CHEMBL4161205)
Show SMILES Clc1ccc(OCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C22H21ClN2O3S/c23-17-6-8-18(9-7-17)27-11-3-12-28-19-5-1-4-16(14-19)15-20-21(26)25-10-2-13-29-22(25)24-20/h1,4-9,14-15H,2-3,10-13H2/b20-15-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449590
PNG
(CHEMBL4160494)
Show SMILES Fc1ccc(COc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C20H17FN2O2S/c21-16-7-5-14(6-8-16)13-25-17-4-1-3-15(11-17)12-18-19(24)23-9-2-10-26-20(23)22-18/h1,3-8,11-12H,2,9-10,13H2/b18-12-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449565
PNG
(CHEMBL4177155)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N=C(NC3=O)SCCc3ccccc3)c2)cc1
Show InChI InChI=1S/C25H21ClN2O2S/c26-21-11-9-19(10-12-21)17-30-22-8-4-7-20(15-22)16-23-24(29)28-25(27-23)31-14-13-18-5-2-1-3-6-18/h1-12,15-16H,13-14,17H2,(H,27,28,29)/b23-16-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449593
PNG
(CHEMBL4163505)
Show SMILES CSC1=NC(=O)\C(N1)=C\c1cccc(OCc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C18H15ClN2O2S/c1-24-18-20-16(17(22)21-18)10-13-3-2-4-15(9-13)23-11-12-5-7-14(19)8-6-12/h2-10H,11H2,1H3,(H,20,21,22)/b16-10-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449585
PNG
(CHEMBL4159707)
Show SMILES Clc1ccc(COc2cccc(\C=C3/NC(=S)NC3=O)c2)cc1
Show InChI InChI=1S/C17H13ClN2O2S/c18-13-6-4-11(5-7-13)10-22-14-3-1-2-12(8-14)9-15-16(21)20-17(23)19-15/h1-9H,10H2,(H2,19,20,21,23)/b15-9-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449584
PNG
(CHEMBL4169939)
Show SMILES Clc1ccc(OCCCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C27H31ClN2O3S/c28-22-11-13-23(14-12-22)32-16-5-3-1-2-4-6-17-33-24-10-7-9-21(19-24)20-25-26(31)30-15-8-18-34-27(30)29-25/h7,9-14,19-20H,1-6,8,15-18H2/b25-20-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449583
PNG
(CHEMBL4160778)
Show SMILES Cc1cccc(C)c1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1
Show InChI InChI=1S/C27H32N2O3S/c1-20-10-7-11-21(2)25(20)32-16-6-4-3-5-15-31-23-13-8-12-22(18-23)19-24-26(30)29-14-9-17-33-27(29)28-24/h7-8,10-13,18-19H,3-6,9,14-17H2,1-2H3/b24-19-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449579
PNG
(CHEMBL4172931)
Show SMILES Cc1ccc(COc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C21H20N2O2S/c1-15-6-8-16(9-7-15)14-25-18-5-2-4-17(12-18)13-19-20(24)23-10-3-11-26-21(23)22-19/h2,4-9,12-13H,3,10-11,14H2,1H3/b19-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449591
PNG
(CHEMBL4165882)
Show SMILES CN1C(=O)\C(=C\c2cccc(OCc3ccc(Cl)cc3)c2)N=C1SCc1ccc(C)cc1
Show InChI InChI=1S/C26H23ClN2O2S/c1-18-6-8-20(9-7-18)17-32-26-28-24(25(30)29(26)2)15-21-4-3-5-23(14-21)31-16-19-10-12-22(27)13-11-19/h3-15H,16-17H2,1-2H3/b24-15-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449600
PNG
(CHEMBL4159050)
Show SMILES Fc1ccc(CSC2=N\C(=C/c3cccc(OCc4ccc(Cl)cc4)c3)C(=O)N2)cc1
Show InChI InChI=1S/C24H18ClFN2O2S/c25-19-8-4-16(5-9-19)14-30-21-3-1-2-18(12-21)13-22-23(29)28-24(27-22)31-15-17-6-10-20(26)11-7-17/h1-13H,14-15H2,(H,27,28,29)/b22-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449594
PNG
(CHEMBL4159299)
Show SMILES Clc1ccc(COc2cccc(\C=C3/SC(=O)NC3=O)c2)cc1
Show InChI InChI=1S/C17H12ClNO3S/c18-13-6-4-11(5-7-13)10-22-14-3-1-2-12(8-14)9-15-16(20)19-17(21)23-15/h1-9H,10H2,(H,19,20,21)/b15-9-
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University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449592
PNG
(CHEMBL4170995)
Show SMILES Clc1cccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)c1
Show InChI InChI=1S/C25H27ClN2O3S/c26-20-9-6-11-22(18-20)31-14-4-2-1-3-13-30-21-10-5-8-19(16-21)17-23-24(29)28-12-7-15-32-25(28)27-23/h5-6,8-11,16-18H,1-4,7,12-15H2/b23-17-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449598
PNG
(CHEMBL4176317)
Show SMILES Clc1ccc(OCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C24H25ClN2O3S/c25-19-8-10-20(11-9-19)29-13-2-1-3-14-30-21-7-4-6-18(16-21)17-22-23(28)27-12-5-15-31-24(27)26-22/h4,6-11,16-17H,1-3,5,12-15H2/b22-17-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449596
PNG
(CHEMBL4163080)
Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1
Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449564
PNG
(CHEMBL4171815)
Show SMILES Clc1ccc(OCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C23H23ClN2O3S/c24-18-7-9-19(10-8-18)28-12-1-2-13-29-20-6-3-5-17(15-20)16-21-22(27)26-11-4-14-30-23(26)25-21/h3,5-10,15-16H,1-2,4,11-14H2/b21-16-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449562
PNG
(CHEMBL4165036)
Show SMILES O=C1N2CCCSC2=N\C1=C/c1cccc(OCCc2ccccc2)c1
Show InChI InChI=1S/C21H20N2O2S/c24-20-19(22-21-23(20)11-5-13-26-21)15-17-8-4-9-18(14-17)25-12-10-16-6-2-1-3-7-16/h1-4,6-9,14-15H,5,10-13H2/b19-15-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449561
PNG
(CHEMBL4168457)
Show SMILES Clc1ccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C25H27ClN2O3S/c26-20-9-11-21(12-10-20)30-14-3-1-2-4-15-31-22-8-5-7-19(17-22)18-23-24(29)28-13-6-16-32-25(28)27-23/h5,7-12,17-18H,1-4,6,13-16H2/b23-18-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449563
PNG
(CHEMBL4161619)
Show SMILES Clc1ccc(OCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C21H19ClN2O3S/c22-16-5-7-17(8-6-16)26-10-11-27-18-4-1-3-15(13-18)14-19-20(25)24-9-2-12-28-21(24)23-19/h1,3-8,13-14H,2,9-12H2/b19-14-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449567
PNG
(CHEMBL4176334)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N=C4SCCN4C3=O)c2)cc1
Show InChI InChI=1S/C19H15ClN2O2S/c20-15-6-4-13(5-7-15)12-24-16-3-1-2-14(10-16)11-17-18(23)22-8-9-25-19(22)21-17/h1-7,10-11H,8-9,12H2/b17-11-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449601
PNG
(CHEMBL4173804)
Show SMILES Cc1ccc(CSC2=N\C(=C/c3cccc(OCc4ccc(Cl)cc4)c3)C(=O)N2)cc1
Show InChI InChI=1S/C25H21ClN2O2S/c1-17-5-7-19(8-6-17)16-31-25-27-23(24(29)28-25)14-20-3-2-4-22(13-20)30-15-18-9-11-21(26)12-10-18/h2-14H,15-16H2,1H3,(H,27,28,29)/b23-14-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449602
PNG
(CHEMBL4166952)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N=C(NC3=O)SCc3ccccc3)c2)cc1
Show InChI InChI=1S/C24H19ClN2O2S/c25-20-11-9-17(10-12-20)15-29-21-8-4-7-19(13-21)14-22-23(28)27-24(26-22)30-16-18-5-2-1-3-6-18/h1-14H,15-16H2,(H,26,27,28)/b22-14-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449595
PNG
(CHEMBL4169940)
Show SMILES CN1C(=N)NC(=O)\C1=C\c1cccc(OCc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C18H16ClN3O2/c1-22-16(17(23)21-18(22)20)10-13-3-2-4-15(9-13)24-11-12-5-7-14(19)8-6-12/h2-10H,11H2,1H3,(H2,20,21,23)/b16-10-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449597
PNG
(CHEMBL4174825)
Show SMILES Cc1ccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C26H30N2O3S/c1-20-10-12-22(13-11-20)30-15-4-2-3-5-16-31-23-9-6-8-21(18-23)19-24-25(29)28-14-7-17-32-26(28)27-24/h6,8-13,18-19H,2-5,7,14-17H2,1H3/b24-19-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449560
PNG
(CHEMBL4168388)
Show SMILES Brc1ccc(COc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C20H17BrN2O2S/c21-16-7-5-14(6-8-16)13-25-17-4-1-3-15(11-17)12-18-19(24)23-9-2-10-26-20(23)22-18/h1,3-8,11-12H,2,9-10,13H2/b18-12-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449586
PNG
(CHEMBL4171382)
Show SMILES CC(C)c1ccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C28H34N2O3S/c1-21(2)23-11-13-24(14-12-23)32-16-5-3-4-6-17-33-25-10-7-9-22(19-25)20-26-27(31)30-15-8-18-34-28(30)29-26/h7,9-14,19-21H,3-6,8,15-18H2,1-2H3/b26-20-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449581
PNG
(CHEMBL4164171)
Show SMILES CCc1ccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1
Show InChI InChI=1S/C27H32N2O3S/c1-2-21-11-13-23(14-12-21)31-16-5-3-4-6-17-32-24-10-7-9-22(19-24)20-25-26(30)29-15-8-18-33-27(29)28-25/h7,9-14,19-20H,2-6,8,15-18H2,1H3/b25-20-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449599
PNG
(CHEMBL4169536)
Show SMILES O=C1N2CCCSC2=N\C1=C/c1cccc(OCCCc2ccccc2)c1
Show InChI InChI=1S/C22H22N2O2S/c25-21-20(23-22-24(21)12-6-14-27-22)16-18-9-4-11-19(15-18)26-13-5-10-17-7-2-1-3-8-17/h1-4,7-9,11,15-16H,5-6,10,12-14H2/b20-16-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449580
PNG
(CHEMBL4174205)
Show SMILES CSC1=N\C(=C/c2cccc(OCc3ccc(Cl)cc3)c2)C(=O)N1C
Show InChI InChI=1S/C19H17ClN2O2S/c1-22-18(23)17(21-19(22)25-2)11-14-4-3-5-16(10-14)24-12-13-6-8-15(20)9-7-13/h3-11H,12H2,1-2H3/b17-11-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449577
PNG
(CHEMBL4162436)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N=C(NC3=O)SCc3ccc(Br)cc3)c2)cc1
Show InChI InChI=1S/C24H18BrClN2O2S/c25-19-8-4-17(5-9-19)15-31-24-27-22(23(29)28-24)13-18-2-1-3-21(12-18)30-14-16-6-10-20(26)11-7-16/h1-13H,14-15H2,(H,27,28,29)/b22-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449588
PNG
(CHEMBL4169314)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N4CCSC4=NC3=O)c2)cc1
Show InChI InChI=1S/C19H15ClN2O2S/c20-15-6-4-13(5-7-15)12-24-16-3-1-2-14(10-16)11-17-18(23)21-19-22(17)8-9-25-19/h1-7,10-11H,8-9,12H2/b17-11-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50449582
PNG
(CHEMBL4170355)
Show SMILES Clc1ccc(COc2cccc(\C=C3/N=C(NC3=O)SCc3ccc(Cl)cc3)c2)cc1
Show InChI InChI=1S/C24H18Cl2N2O2S/c25-19-8-4-16(5-9-19)14-30-21-3-1-2-18(12-21)13-22-23(29)28-24(27-22)31-15-17-6-10-20(26)11-7-17/h1-13H,14-15H2,(H,27,28,29)/b22-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f...


Eur J Med Chem 155: 381-397 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50448073
PNG
(CHEMBL3120631)
Show SMILES CC(C)=CCC[C@]1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C34H49NO6/c1-19(2)9-8-15-32(3)25-13-12-20-17-22-21-10-6-7-11-23(21)35-30(22)34(20,5)33(25,4)16-14-26(32)41-31-29(39)28(38)27(37)24(18-36)40-31/h6-7,9-11,20,24-29,31,35-39H,8,12-18H2,1-5H3/t20-,24+,25-,26-,27+,28-,29-,31-,32-,33-,34+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 10 uM THC-mediated beta-arrestin recruitment after 90 mins by bet...


J Nat Prod 77: 673-7 (2014)


Article DOI: 10.1021/np400850g
BindingDB Entry DOI: 10.7270/Q2154JJZ
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50448074
PNG
(EMINDOLE SB | Emindole Sb)
Show SMILES CC(C)=CCC[C@]1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C
Show InChI InChI=1S/C28H39NO/c1-18(2)9-8-15-26(3)23-13-12-19-17-21-20-10-6-7-11-22(20)29-25(21)28(19,5)27(23,4)16-14-24(26)30/h6-7,9-11,19,23-24,29-30H,8,12-17H2,1-5H3/t19-,23-,24-,26-,27-,28+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 10 uM THC-mediated beta-arrestin recruitment after 90 mins by bet...


J Nat Prod 77: 673-7 (2014)


Article DOI: 10.1021/np400850g
BindingDB Entry DOI: 10.7270/Q2154JJZ
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50448075
PNG
(CHEMBL1258979)
Show SMILES CC(C)=C[C@H]1C[C@]2(C)[C@H](CC[C@@]3(C)[C@H]2CC[C@H]2Cc4c([nH]c5ccccc45)[C@]32C)O1
Show InChI InChI=1S/C28H37NO/c1-17(2)14-19-16-26(3)23-11-10-18-15-21-20-8-6-7-9-22(20)29-25(21)28(18,5)27(23,4)13-12-24(26)30-19/h6-9,14,18-19,23-24,29H,10-13,15-16H2,1-5H3/t18-,19-,23-,24-,26-,27-,28+/m0/s1
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n/an/a 9.91E+3n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inverse agonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 7.5 uM THC-mediated beta-arrestin recruitment after 90 mins ...


J Nat Prod 77: 673-7 (2014)


Article DOI: 10.1021/np400850g
BindingDB Entry DOI: 10.7270/Q2154JJZ
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50448076
PNG
(CHEMBL3120632)
Show SMILES COC(C)(C)\C=C\C[C@]1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C
Show InChI InChI=1S/C29H41NO2/c1-26(2,32-6)15-9-16-27(3)23-13-12-19-18-21-20-10-7-8-11-22(20)30-25(21)29(19,5)28(23,4)17-14-24(27)31/h7-11,15,19,23-24,30-31H,12-14,16-18H2,1-6H3/b15-9+/t19-,23-,24-,27-,28-,29+/m0/s1
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n/an/a 1.34E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inverse agonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 7.5 uM THC-mediated beta-arrestin recruitment after 90 mins ...


J Nat Prod 77: 673-7 (2014)


Article DOI: 10.1021/np400850g
BindingDB Entry DOI: 10.7270/Q2154JJZ
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50398237
PNG
(CHEMBL2177249)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3cccc(OC)c3)c(=O)oc2c1
Show InChI InChI=1S/C23H26O4/c1-4-5-6-8-17-13-21(26-3)20-15-18(23(24)27-22(20)14-17)11-16-9-7-10-19(12-16)25-2/h7,9-10,12-15H,4-6,8,11H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50398229
PNG
(CHEMBL2177257)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C23H26O4/c1-4-5-6-9-16-12-21(26-3)19-15-18(23(24)27-22(19)13-16)14-17-10-7-8-11-20(17)25-2/h7-8,10-13,15H,4-6,9,14H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434876
PNG
(CHEMBL2387539)
Show SMILES Cc1ccccc1Cc1cc2c(C)c(O)c(C)c(C)c2oc1=O
Show InChI InChI=1S/C20H20O3/c1-11-7-5-6-8-15(11)9-16-10-17-14(4)18(21)12(2)13(3)19(17)23-20(16)22/h5-8,10,21H,9H2,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434877
PNG
(CHEMBL2387538)
Show SMILES COc1c(C)c(C)c2oc(=O)c(Cc3ccccc3C)cc2c1C
Show InChI InChI=1S/C21H22O3/c1-12-8-6-7-9-16(12)10-17-11-18-15(4)19(23-5)13(2)14(3)20(18)24-21(17)22/h6-9,11H,10H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434878
PNG
(CHEMBL2387536)
Show SMILES COc1c(C)c(C)c2oc(=O)c(Cc3ccc(F)cc3)cc2c1C
Show InChI InChI=1S/C20H19FO3/c1-11-12(2)19-17(13(3)18(11)23-4)10-15(20(22)24-19)9-14-5-7-16(21)8-6-14/h5-8,10H,9H2,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434879
PNG
(CHEMBL2387535)
Show SMILES Cc1c(C)c2oc(=O)c(Cc3ccccc3)cc2c(C)c1O
Show InChI InChI=1S/C19H18O3/c1-11-12(2)18-16(13(3)17(11)20)10-15(19(21)22-18)9-14-7-5-4-6-8-14/h4-8,10,20H,9H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434880
PNG
(CHEMBL2387533)
Show SMILES COc1ccccc1Cc1cc2c(C)c(OC)c(C)c(C)c2oc1=O
Show InChI InChI=1S/C21H22O4/c1-12-13(2)20-17(14(3)19(12)24-5)11-16(21(22)25-20)10-15-8-6-7-9-18(15)23-4/h6-9,11H,10H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50434881
PNG
(CHEMBL2181545)
Show SMILES CCCCC1(CCCCC1)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C28H34O4/c1-4-5-13-28(14-9-6-10-15-28)22-18-25(31-3)23-17-21(27(29)32-26(23)19-22)16-20-11-7-8-12-24(20)30-2/h7-8,11-12,17-19H,4-6,9-10,13-16H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50398217
PNG
(CHEMBL2181543)
Show SMILES CCCCC1(CCCC1)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C27H32O4/c1-4-5-12-27(13-8-9-14-27)21-17-24(30-3)22-16-20(26(28)31-25(22)18-21)15-19-10-6-7-11-23(19)29-2/h6-7,10-11,16-18H,4-5,8-9,12-15H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens (Human))
BDBM50398218
PNG
(CHEMBL2181542)
Show SMILES CCCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3O)c(=O)oc2c1
Show InChI InChI=1S/C26H32O4/c1-4-5-6-7-10-13-26(2,3)20-16-23(28)21-15-19(25(29)30-24(21)17-20)14-18-11-8-9-12-22(18)27/h8-9,11-12,15-17,27-28H,4-7,10,13-14H2,1-3H3
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n/an/a 1.25E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


J Med Chem 56: 4798-810 (2013)


Article DOI: 10.1021/jm4005175
BindingDB Entry DOI: 10.7270/Q2GM88QX
More data for this
Ligand-Target Pair
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