Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50228363![]() (CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Activation of human SirT2 protein fluorescence polarization assay | Nat Chem Biol 4: 590-7 (2008) Article DOI: 10.1038/nchembio.111 BindingDB Entry DOI: 10.7270/Q2JD4X1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50428988![]() (CHEMBL2333666) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Activation of at N-terminal GST-tagged SIRT2 (34 to 356 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac... | J Med Chem 56: 761-80 (2013) Article DOI: 10.1021/jm301032j BindingDB Entry DOI: 10.7270/Q2XP768M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM31963![]() (carbohydrazide derivative, 5f) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Activation of at N-terminal GST-tagged SIRT2 (34 to 356 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac... | J Med Chem 56: 761-80 (2013) Article DOI: 10.1021/jm301032j BindingDB Entry DOI: 10.7270/Q2XP768M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50228363![]() (CHEMBL257991 | N-(2-(3-(piperazin-1-ylmethyl)imida...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a |
Sirtris Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Activation of SIRT2 by mass spectrometry assay | Nature 450: 712-716 (2007) Article DOI: 10.1038/nature06261 BindingDB Entry DOI: 10.7270/Q2765G67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50376978![]() (CHEMBL403308 | SRT-2183) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Sirtris Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Activation of SIRT2 by mass spectrometry assay | Nature 450: 712-716 (2007) Article DOI: 10.1038/nature06261 BindingDB Entry DOI: 10.7270/Q2765G67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50228364![]() (3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Sirtris Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Activation of SIRT2 by mass spectrometry assay | Nature 450: 712-716 (2007) Article DOI: 10.1038/nature06261 BindingDB Entry DOI: 10.7270/Q2765G67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM23926![]() ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Sirtris Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Activation of SIRT2 by mass spectrometry assay | Nature 450: 712-716 (2007) Article DOI: 10.1038/nature06261 BindingDB Entry DOI: 10.7270/Q2765G67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50513317![]() (CHEMBL4465620) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu... | J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50168905![]() (CHEMBL3805692) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of full length human recombinant N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21(DE3) cells using Ac-RHK-K(Ac)-AMC as subs... | J Med Chem 59: 2928-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01376 BindingDB Entry DOI: 10.7270/Q2Z89F9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50168493![]() (CHEMBL3805479) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of full length human recombinant N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21(DE3) cells using Ac-RHK-K(Ac)-AMC as subs... | J Med Chem 59: 2928-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01376 BindingDB Entry DOI: 10.7270/Q2Z89F9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50168921![]() (CHEMBL3806257) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of full length human recombinant N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21(DE3) cells using Ac-RHK-K(Ac)-AMC as subs... | J Med Chem 59: 2928-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01376 BindingDB Entry DOI: 10.7270/Q2Z89F9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50168918![]() (CHEMBL3806063) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of full length human recombinant N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21(DE3) cells using Ac-RHK-K(Ac)-AMC as subs... | J Med Chem 59: 2928-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01376 BindingDB Entry DOI: 10.7270/Q2Z89F9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50513318![]() (CHEMBL4516553) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu... | J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50148827![]() (CHEMBL3769975) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College Curated by ChEMBL | Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using tubulin-K40 peptide in prese... | J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50236570![]() (CHEMBL4072206) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bayreuth Curated by ChEMBL | Assay Description Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich... | J Med Chem 60: 2344-2360 (2017) Article DOI: 10.1021/acs.jmedchem.6b01609 BindingDB Entry DOI: 10.7270/Q2J968NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50236570![]() (CHEMBL4072206) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bayreuth Curated by ChEMBL | Assay Description Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich... | J Med Chem 60: 2344-2360 (2017) Article DOI: 10.1021/acs.jmedchem.6b01609 BindingDB Entry DOI: 10.7270/Q2J968NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50070588![]() (CHEMBL3408821) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National University of Singapore Curated by ChEMBL | Assay Description Non-competitive inhibition of human recombinant SIRT2 using Z-QPK(Me)2K(Ac) as substrate assessed as decrease in maximal enzyme activity preincubated... | Eur J Med Chem 92: 145-55 (2015) Article DOI: 10.1016/j.ejmech.2014.12.027 BindingDB Entry DOI: 10.7270/Q270834V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50070588![]() (CHEMBL3408821) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National University of Singapore Curated by ChEMBL | Assay Description Non-competitive inhibition of human recombinant SIRT2 using Z-QPK(Me)2K(Ac) as substrate assessed as decrease in maximal enzyme activity preincubated... | Eur J Med Chem 92: 145-55 (2015) Article DOI: 10.1016/j.ejmech.2014.12.027 BindingDB Entry DOI: 10.7270/Q270834V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50193046![]() (CHEMBL3969626) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Jambheshwar University of Science and Technology Curated by ChEMBL | Assay Description Competitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent peptide substrate in presence of NAD+ by Lineweaver-Burk p... | Eur J Med Chem 119: 45-69 (2016) Article DOI: 10.1016/j.ejmech.2016.04.063 BindingDB Entry DOI: 10.7270/Q2VH5QTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50193046![]() (CHEMBL3969626) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Jambheshwar University of Science and Technology Curated by ChEMBL | Assay Description Noncompetitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by Lineweaver-Burk plot a... | Eur J Med Chem 119: 45-69 (2016) Article DOI: 10.1016/j.ejmech.2016.04.063 BindingDB Entry DOI: 10.7270/Q2VH5QTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM29589![]() (Faridak | LBH-589 | LBH-589B | Panobinostat | US10...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health R&D Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50463739![]() (CHEMBL4237803) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health R&D Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50463743![]() (CHEMBL4241370) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health R&D Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50463738![]() (CHEMBL4244764) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health R&D Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50105327![]() (JNJ-26481585 | QUISINOSTAT | Quisinostat) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health R&D Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using fluoro-lysine sirtuin 2 deacetylase substrate after 60 mins by fluorimetrc method | Bioorg Med Chem Lett 28: 2985-2992 (2018) Article DOI: 10.1016/j.bmcl.2018.06.029 BindingDB Entry DOI: 10.7270/Q2M0484T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431098![]() (CHEMBL2338821) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431099![]() (CHEMBL2338820) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431100![]() (CHEMBL2338819) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431101![]() (CHEMBL2338818) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431102![]() (CHEMBL2338817) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431103![]() (CHEMBL2338816) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431104![]() (CHEMBL2338815) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431089![]() (CHEMBL2338814) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431090![]() (CHEMBL2338813) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431091![]() (CHEMBL2338812) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431092![]() (CHEMBL2338811) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431093![]() (CHEMBL2338810) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431094![]() (CHEMBL2338809) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431095![]() (CHEMBL2338808) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431096![]() (CHEMBL2332055) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431105![]() (CHEMBL2332054) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431106![]() (CHEMBL2332053) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431107![]() (CHEMBL2332052) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431108![]() (CHEMBL2332051) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431109![]() (CHEMBL2332050) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431110![]() (CHEMBL2332049) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431111![]() (CHEMBL2332048) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431112![]() (CHEMBL2332047) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431113![]() (CHEMBL2332046) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human)) | BDBM50431114![]() (CHEMBL2332045) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Sirtris a GSK Company Curated by ChEMBL | Assay Description Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat... | J Med Chem 56: 3666-79 (2013) Article DOI: 10.1021/jm400204k BindingDB Entry DOI: 10.7270/Q2D50P9C | |||||||||||
More data for this Ligand-Target Pair |
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