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Compile Data Set for Download or QSAR

Found 177 hits Enz. Inhib. hit(s) with Target = 'Neuraminidase A'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuraminidase A


(Influenza A virus (A/Shangdong/9/93(H3N2)))
BDBM4934
PNG
((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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1 -53.4 5n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 7: 1837-42 (1997)


Article DOI: 10.1021/jm048989d
BindingDB Entry DOI: 10.7270/Q2FX77MK
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5202
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES C\C=C/[C@@H]1C[C@@H](N[C@H]1[C@H](CC(C)C)NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H26N2O3/c1-5-6-11-8-13(15(19)20)17-14(11)12(7-9(2)3)16-10(4)18/h5-6,9,11-14,17H,7-8H2,1-4H3,(H,16,18)(H,19,20)/b6-5-/t11-,12+,13-,14-/m1/s1
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20n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5200
PNG
((+/-)-(2R,4R,5R,1 S)-5-(1 -Acetylamino-3 -methylbu...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1ccn[nH]1)C(O)=O
Show InChI InChI=1S/C15H24N4O3/c1-8(2)6-12(17-9(3)20)14-10(11-4-5-16-19-11)7-13(18-14)15(21)22/h4-5,8,10,12-14,18H,6-7H2,1-3H3,(H,16,19)(H,17,20)(H,21,22)/t10-,12-,13+,14+/m0/s1
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45 -41.5n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5207
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1\C=C/Cl)C(O)=O
Show InChI InChI=1S/C14H23ClN2O3/c1-8(2)6-11(16-9(3)18)13-10(4-5-15)7-12(17-13)14(19)20/h4-5,8,10-13,17H,6-7H2,1-3H3,(H,16,18)(H,19,20)/b5-4-/t10-,11+,12-,13-/m1/s1
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79n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5202
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES C\C=C/[C@@H]1C[C@@H](N[C@H]1[C@H](CC(C)C)NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H26N2O3/c1-5-6-11-8-13(15(19)20)17-14(11)12(7-9(2)3)16-10(4)18/h5-6,9,11-14,17H,7-8H2,1-4H3,(H,16,18)(H,19,20)/b6-5-/t11-,12+,13-,14-/m1/s1
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150n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5195
PNG
((+/-)-(2R,4R,5S,1 S)-5-(1 -Acetylamino-3 -methylbu...)
Show SMILES COC(=O)[C@@H]1C[C@@H](N[C@H]1[C@H](CC(C)C)NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H24N2O5/c1-7(2)5-10(15-8(3)17)12-9(14(20)21-4)6-11(16-12)13(18)19/h7,9-12,16H,5-6H2,1-4H3,(H,15,17)(H,18,19)/t9-,10+,11-,12-/m1/s1
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260 -37.2n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5201
PNG
((2R,4R,5R)-5-[(1S)-1-acetamido-3-methylbutyl]-4-(1...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1ccon1)C(O)=O
Show InChI InChI=1S/C15H23N3O4/c1-8(2)6-12(16-9(3)19)14-10(11-4-5-22-18-11)7-13(17-14)15(20)21/h4-5,8,10,12-14,17H,6-7H2,1-3H3,(H,16,19)(H,20,21)/t10-,12-,13+,14+/m0/s1
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270n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5203
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1C=C)C(O)=O
Show InChI InChI=1S/C14H24N2O3/c1-5-10-7-12(14(18)19)16-13(10)11(6-8(2)3)15-9(4)17/h5,8,10-13,16H,1,6-7H2,2-4H3,(H,15,17)(H,18,19)/t10-,11+,12-,13-/m1/s1
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300n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5198
PNG
((+/-)-(2R,4R,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1nccs1)C(O)=O
Show InChI InChI=1S/C15H23N3O3S/c1-8(2)6-11(17-9(3)19)13-10(14-16-4-5-22-14)7-12(18-13)15(20)21/h4-5,8,10-13,18H,6-7H2,1-3H3,(H,17,19)(H,20,21)/t10-,11+,12-,13-/m1/s1
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310 -36.8n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5197
PNG
((+/-)-(2R,4R,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1cscn1)C(O)=O
Show InChI InChI=1S/C15H23N3O3S/c1-8(2)4-11(17-9(3)19)14-10(13-6-22-7-16-13)5-12(18-14)15(20)21/h6-8,10-12,14,18H,4-5H2,1-3H3,(H,17,19)(H,20,21)/t10-,11-,12+,14+/m0/s1
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350 -36.5n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5199
PNG
((+/-)-(2R,4R,5R,1 S)-5-(1 -Acetylamino-3 -methylbu...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1ncc[nH]1)C(O)=O
Show InChI InChI=1S/C15H24N4O3/c1-8(2)6-11(18-9(3)20)13-10(14-16-4-5-17-14)7-12(19-13)15(21)22/h4-5,8,10-13,19H,6-7H2,1-3H3,(H,16,17)(H,18,20)(H,21,22)/t10-,11+,12-,13-/m1/s1
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350 -36.5n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5205
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1C=C(C)C)C(O)=O
Show InChI InChI=1S/C16H28N2O3/c1-9(2)6-12-8-14(16(20)21)18-15(12)13(7-10(3)4)17-11(5)19/h6,10,12-15,18H,7-8H2,1-5H3,(H,17,19)(H,20,21)/t12-,13+,14-,15-/m1/s1
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390n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5206
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1C=C(F)F)C(O)=O
Show InChI InChI=1S/C14H22F2N2O3/c1-7(2)4-10(17-8(3)19)13-9(6-12(15)16)5-11(18-13)14(20)21/h6-7,9-11,13,18H,4-5H2,1-3H3,(H,17,19)(H,20,21)/t9-,10-,11+,13+/m0/s1
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420n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5196
PNG
((+/-)-(2R,4R,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1c1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C15H24N4O3/c1-8(2)4-11(18-9(3)20)14-10(13-6-16-7-17-13)5-12(19-14)15(21)22/h6-8,10-12,14,19H,4-5H2,1-3H3,(H,16,17)(H,18,20)(H,21,22)/t10-,11-,12+,14+/m0/s1
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610 -35.1n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A (NanA)


(Streptococcus pneumoniae)
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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1.60E+3n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Siena



Assay Description
Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37░C and stopped by the addition of 0.5 M Na2CO...


BMC Biochem 13: 19 (2012)


Article DOI: 10.1186/1471-2091-13-19
BindingDB Entry DOI: 10.7270/Q2959GDQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A (NanA)


(Streptococcus pneumoniae)
BDBM4994
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)
Show SMILES CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
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1.77E+3n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Siena



Assay Description
Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37░C and stopped by the addition of 0.5 M Na2CO...


BMC Biochem 13: 19 (2012)


Article DOI: 10.1186/1471-2091-13-19
BindingDB Entry DOI: 10.7270/Q2959GDQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (A/Tokyo/3/67(H2N2)))
BDBM5207
PNG
((+/-)-(2R,4S,5R,1 S)-5-(1 -Acetylamino-3 -methyl-b...)
Show SMILES CC(C)C[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1\C=C/Cl)C(O)=O
Show InChI InChI=1S/C14H23ClN2O3/c1-8(2)6-11(16-9(3)18)13-10(4-5-15)7-12(17-13)14(19)20/h4-5,8,10-13,17H,6-7H2,1-3H3,(H,16,18)(H,19,20)/b5-4-/t10-,11+,12-,13-/m1/s1
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3.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
A fluorogenic assay was used to measure influenza virus neuraminidase activity. The substrate, 4-methylumbelliferyl-N-acetylneuraminic acid, is cleav...


J Med Chem 48: 3980-90 (2005)


Article DOI: 10.1021/jm049276y
BindingDB Entry DOI: 10.7270/Q2KP80B9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Shangdong/9/93(H3N2)))
BDBM5210
PNG
(3-carbamimidamido-4-acetamido-5-[(1S,2R)-1,2,3-tri...)
Show SMILES CC(=O)Nc1c(cc(cc1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C13H18N4O6/c1-5(19)16-10-7(11(21)9(20)4-18)2-6(12(22)23)3-8(10)17-13(14)15/h2-3,9,11,18,20-21H,4H2,1H3,(H,16,19)(H,22,23)(H4,14,15,17)/t9-,11+/m1/s1
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>1.00E+5>-23.7>1.00E+5n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 7: 1837-42 (1997)


Article DOI: 10.1021/jm048989d
BindingDB Entry DOI: 10.7270/Q2FX77MK
More data for this
Ligand-Target Pair
Neuraminidase A (NanA)


(Streptococcus pneumoniae)
BDBM4934
PNG
((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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7.20E+5n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Siena



Assay Description
Briefly, the reaction mixtures containing the substrates and up to 100 nM sialidase were incubated at 37░C and stopped by the addition of 0.5 M Na2CO...


BMC Biochem 13: 19 (2012)


Article DOI: 10.1186/1471-2091-13-19
BindingDB Entry DOI: 10.7270/Q2959GDQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (N9))
BDBM4701
PNG
(4-benzamidobenzoic acid | Benzoic Acid deriv. 14)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H11NO3/c16-13(10-4-2-1-3-5-10)15-12-8-6-11(7-9-12)14(17)18/h1-9H,(H,15,16)(H,17,18)
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n/an/a 1.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4703
PNG
(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
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n/an/a 2.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4704
PNG
(3-(Cyanoamino)benzoic Acid | Benzoic Acid deriv. 6...)
Show SMILES OC(=O)c1cccc(NC#N)c1
Show InChI InChI=1S/C8H6N2O2/c9-5-10-7-3-1-2-6(4-7)8(11)12/h1-4,10H,(H,11,12)
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n/an/a 4.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4705
PNG
(3-carbamimidamidobenzoic acid | Benzoic Acid deriv...)
Show SMILES NC(N)=Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C8H9N3O2/c9-8(10)11-6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)(H4,9,10,11)
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n/an/a 5.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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n/an/a 1.30E+4n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (N9))
BDBM4707
PNG
(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Show SMILES CC(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 2.50E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4708
PNG
(4-(Acetylamino)-3-[(hydroxyimino)methyl]benzoic Ac...)
Show SMILES CC(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C10H10N2O4/c1-6(13)12-9-3-2-7(10(14)15)4-8(9)5-11-16/h2-4H,5H2,1H3,(H,12,13)(H,14,15)
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n/an/a 5.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4709
PNG
(4-(Acetylamino)-3-(2-nitroethyl)benzoic Acid | 4-a...)
Show SMILES CC(=O)Nc1ccc(cc1CC[N+]([O-])=O)C(O)=O
Show InChI InChI=1S/C11H12N2O5/c1-7(14)12-10-3-2-9(11(15)16)6-8(10)4-5-13(17)18/h2-3,6H,4-5H2,1H3,(H,12,14)(H,15,16)
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n/an/a 2.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4710
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfonyl)ami...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C9H12N4O4S/c1-18(16,17)13-6-3-2-5(8(14)15)4-7(6)12-9(10)11/h2-4,13H,1H3,(H,14,15)(H4,10,11,12)
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n/an/a 1.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4711
PNG
(3-[(1E)-(hydroxyimino)methyl]-4-methanesulfonamido...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C9H10N2O5S/c1-17(15,16)11-8-3-2-6(9(12)13)4-7(8)5-10-14/h2-4,11H,5H2,1H3,(H,12,13)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4712
PNG
(3-[(Aminoiminomethyl)amino]-4-[(2-methylpropionyl)...)
Show SMILES CC(C)C(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C12H16N4O3/c1-6(2)10(17)15-8-4-3-7(11(18)19)5-9(8)16-12(13)14/h3-6H,1-2H3,(H,15,17)(H,18,19)(H4,13,14,16)
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n/an/a 1.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4713
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylamino)carbon...)
Show SMILES CNC(=O)c1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-13-8(15)6-3-2-5(9(16)17)4-7(6)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 5.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4714
PNG
(3-[(Aminoiminomethyl)amino]-4-(aminosulfonyl)benzo...)
Show SMILES NC(N)=Nc1cc(ccc1S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C8H10N4O4S/c9-8(10)12-5-3-4(7(13)14)1-2-6(5)17(11,15)16/h1-3H,(H,13,14)(H4,9,10,12)(H2,11,15,16)
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n/an/a 9.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4715
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfoxy)meth...)
Show SMILES CS(=O)Cc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H13N3O3S/c1-17(16)5-7-3-2-6(9(14)15)4-8(7)13-10(11)12/h2-4H,5H2,1H3,(H,14,15)(H4,11,12,13)
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n/an/a 1.40E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4716
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfonyl)-me...)
Show SMILES CS(=O)(=O)Cc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H13N3O4S/c1-18(16,17)5-7-3-2-6(9(14)15)4-8(7)13-10(11)12/h2-4H,5H2,1H3,(H,14,15)(H4,11,12,13)
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n/an/a 3.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4717
PNG
(3-amino-5-carbamimidamidobenzoic acid | Benzoic Ac...)
Show SMILES NC(N)=Nc1cc(N)cc(c1)C(O)=O
Show InChI InChI=1S/C8H10N4O2/c9-5-1-4(7(13)14)2-6(3-5)12-8(10)11/h1-3H,9H2,(H,13,14)(H4,10,11,12)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4718
PNG
(3,5-Bis[(aminoiminomethyl)amino]benzoic Acid | 3,5...)
Show SMILES NC(N)=Nc1cc(NC(N)=N)cc(c1)C(O)=O
Show InChI InChI=1S/C9H12N6O2/c10-8(11)14-5-1-4(7(16)17)2-6(3-5)15-9(12)13/h1-3H,(H,16,17)(H4,10,11,14)(H4,12,13,15)
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n/an/a 1.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4719
PNG
(3-carbamimidamido-5-[(1Z)-(hydroxyimino)methyl]ben...)
Show SMILES NC(N)=Nc1cc(CN=O)cc(c1)C(O)=O
Show InChI InChI=1S/C9H10N4O3/c10-9(11)13-7-2-5(4-12-16)1-6(3-7)8(14)15/h1-3H,4H2,(H,14,15)(H4,10,11,13)
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n/an/a 5.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4707
PNG
(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Show SMILES CC(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 2.50E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4708
PNG
(4-(Acetylamino)-3-[(hydroxyimino)methyl]benzoic Ac...)
Show SMILES CC(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C10H10N2O4/c1-6(13)12-9-3-2-7(10(14)15)4-8(9)5-11-16/h2-4H,5H2,1H3,(H,12,13)(H,14,15)
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n/an/a 5.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4722
PNG
(3-carbamimidamido-4-acetamido-5-(1,2,3-trihydroxyp...)
Show SMILES CC(=O)Nc1c(cc(cc1C(O)C(O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C13H18N4O6/c1-5(19)16-10-7(11(21)9(20)4-18)2-6(12(22)23)3-8(10)17-13(14)15/h2-3,9,11,18,20-21H,4H2,1H3,(H,16,19)(H,22,23)(H4,14,15,17)
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n/an/a>1.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4723
PNG
(3,5-dicarbamimidamido-4-acetamidobenzoic acid | Be...)
Show SMILES CC(=O)Nc1c(cc(cc1N=C(N)N)C(O)=O)N=C(N)N
Show InChI InChI=1S/C11H15N7O3/c1-4(19)16-8-6(17-10(12)13)2-5(9(20)21)3-7(8)18-11(14)15/h2-3H,1H3,(H,16,19)(H,20,21)(H4,12,13,17)(H4,14,15,18)
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n/an/a 1.00E+4n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4724
PNG
(3,5-dicarbamimidamido-4-(pentan-3-yloxy)benzoic ac...)
Show SMILES CCC(CC)Oc1c(cc(cc1N=C(N)N)C(O)=O)N=C(N)N
Show InChI InChI=1S/C14H22N6O3/c1-3-8(4-2)23-11-9(19-13(15)16)5-7(12(21)22)6-10(11)20-14(17)18/h5-6,8H,3-4H2,1-2H3,(H,21,22)(H4,15,16,19)(H4,17,18,20)
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n/an/a 3.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4710
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfonyl)ami...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C9H12N4O4S/c1-18(16,17)13-6-3-2-5(8(14)15)4-7(6)12-9(10)11/h2-4,13H,1H3,(H,14,15)(H4,10,11,12)
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n/an/a 1.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4711
PNG
(3-[(1E)-(hydroxyimino)methyl]-4-methanesulfonamido...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C9H10N2O5S/c1-17(15,16)11-8-3-2-6(9(12)13)4-7(8)5-10-14/h2-4,11H,5H2,1H3,(H,12,13)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4727
PNG
(3-carbamimidamido-4-acetamido-5-(2-hydroxyethyl)be...)
Show SMILES CC(=O)Nc1c(CCO)cc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C12H16N4O4/c1-6(18)15-10-7(2-3-17)4-8(11(19)20)5-9(10)16-12(13)14/h4-5,17H,2-3H2,1H3,(H,15,18)(H,19,20)(H4,13,14,16)
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n/an/a 4.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4728
PNG
(3-(Aminoiminomethyl)amino-5-hydroxymethyl-4-(methy...)
Show SMILES CS(=O)(=O)Nc1c(CO)cc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H14N4O5S/c1-20(18,19)14-8-6(4-15)2-5(9(16)17)3-7(8)13-10(11)12/h2-3,14-15H,4H2,1H3,(H,16,17)(H4,11,12,13)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4729
PNG
(3-carbamimidamido-5-[(1E)-(hydroxyimino)methyl]-4-...)
Show SMILES CS(=O)(=O)Nc1c(CN=O)cc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H13N5O5S/c1-21(19,20)15-8-6(4-13-18)2-5(9(16)17)3-7(8)14-10(11)12/h2-3,15H,4H2,1H3,(H,16,17)(H4,11,12,14)
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n/an/a 8.00E+4n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4730
PNG
(5-(Methylsulfonylamino)pyridine-2-carboxylic acid ...)
Show SMILES CS(=O)(=O)Nc1ccc(nc1)C(O)=O
Show InChI InChI=1S/C7H8N2O4S/c1-14(12,13)9-5-2-3-6(7(10)11)8-4-5/h2-4,9H,1H3,(H,10,11)
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n/an/a 3.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4731
PNG
(5-Acetylaminopyridine-2-carboxylic acid, sodium sa...)
Show SMILES CC(=O)Nc1ccc(nc1)C(O)=O
Show InChI InChI=1S/C8H8N2O3/c1-5(11)10-6-2-3-7(8(12)13)9-4-6/h2-4H,1H3,(H,10,11)(H,12,13)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4732
PNG
(5-Thioxoethylaminopyridine-2-carboxylic acid, hydr...)
Show SMILES CC(=S)Nc1ccc(nc1)C(O)=O
Show InChI InChI=1S/C8H8N2O2S/c1-5(13)10-6-2-3-7(8(11)12)9-4-6/h2-4H,1H3,(H,10,13)(H,11,12)
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n/an/a 4.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 13: 2665-78 (2005)


Article DOI: 10.1016/j.bmc.2005.01.042
BindingDB Entry DOI: 10.7270/Q2SF2TD9
More data for this
Ligand-Target Pair
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