Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019424![]() (CHEMBL3290106) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Partial agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay relative to SR142948a | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50041428![]() (CHEMBL3356855) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >10 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assay | Bioorg Med Chem Lett 25: 292-6 (2014) Article DOI: 10.1016/j.bmcl.2014.11.047 BindingDB Entry DOI: 10.7270/Q2M90B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019424![]() (CHEMBL3290106) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Partial agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50041429![]() (CHEMBL3356854) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assay | Bioorg Med Chem Lett 25: 292-6 (2014) Article DOI: 10.1016/j.bmcl.2014.11.047 BindingDB Entry DOI: 10.7270/Q2M90B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM85050![]() (CAS_184162-64-9 | SR 142948A | SR142948 | SR142948...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assay | Bioorg Med Chem Lett 25: 292-6 (2014) Article DOI: 10.1016/j.bmcl.2014.11.047 BindingDB Entry DOI: 10.7270/Q2M90B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019417![]() (CHEMBL3290101) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019423![]() (CHEMBL3290105) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM85050![]() (CAS_184162-64-9 | SR 142948A | SR142948 | SR142948...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019413![]() (CHEMBL3290097) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019411![]() (CHEMBL3290095) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM85050![]() (CAS_184162-64-9 | SR 142948A | SR142948 | SR142948...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 receptor expressed in CHO-K1 cells assessed as calcium mobilization by FLIPR assay | J Med Chem 57: 7472-7 (2014) Article DOI: 10.1021/jm500857r BindingDB Entry DOI: 10.7270/Q2BP04C6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019405![]() (LEVOCABASTINE | R-50547) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019412![]() (CHEMBL3290096) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50322368![]() ((S)-5-((S)-1-((S)-2-((S)-1-((S)-1-((S)-1-carboxy-3...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
Medical University of South Carolina Campus Curated by ChEMBL | Assay Description Binding affinity to human NTR2 by gamma counting | J Med Chem 53: 4623-32 (2010) Article DOI: 10.1021/jm100092s BindingDB Entry DOI: 10.7270/Q2DF6RDK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50069091![]() (CHEMBL3403507) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
RTI International Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 overexpressed in CHO-k1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 25: 2060-4 (2015) Article DOI: 10.1016/j.bmcl.2015.03.083 BindingDB Entry DOI: 10.7270/Q2BZ67RD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019414![]() (CHEMBL3290098) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 62 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019419![]() (CHEMBL3290103) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 68 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019410![]() (CHEMBL3290094) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 94 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50130880![]() (CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assay | Bioorg Med Chem Lett 25: 292-6 (2014) Article DOI: 10.1016/j.bmcl.2014.11.047 BindingDB Entry DOI: 10.7270/Q2M90B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019418![]() (CHEMBL3290102) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 108 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50130880![]() (CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit... | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50248034![]() (2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-ph...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50041427![]() (CHEMBL3356853) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 145 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assay | Bioorg Med Chem Lett 25: 292-6 (2014) Article DOI: 10.1016/j.bmcl.2014.11.047 BindingDB Entry DOI: 10.7270/Q2M90B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019415![]() (CHEMBL3290099) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 159 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019409![]() (CHEMBL3290093) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 166 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019406![]() (CHEMBL3290090) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 216 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM82417![]() (CHEMBL461604 | SR 48527) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 217 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019416![]() (CHEMBL3290100) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 229 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019408![]() (CHEMBL3290092) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 258 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019420![]() (CHEMBL3290104) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 271 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50183343![]() (CHEMBL3818506) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 345 | n/a | n/a | n/a | n/a |
RTI International Curated by ChEMBL | Assay Description Partial agonist activity at rat NTS2 receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem 24: 3758-70 (2016) Article DOI: 10.1016/j.bmc.2016.06.018 BindingDB Entry DOI: 10.7270/Q2MS3VPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50019407![]() (CHEMBL3290091) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 382 | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assay | J Med Chem 57: 5318-32 (2014) Article DOI: 10.1021/jm5003843 BindingDB Entry DOI: 10.7270/Q2PR7XJD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342251![]() ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-2-((S)-2-amino-5-g...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit... | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342244![]() ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-6-amino-2-((S)-2,6...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 590 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit... | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342245![]() ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-2-((S)-2,6-diamino...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit... | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342248![]() ((S)-2-((2S,3S)-2-(2-((S)-1-((S)-6-amino-2-((S)-2-a...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 840 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Agonist activity at human NTS2 receptor expressed in HEK293 cells assessed as inhibition of constitutive activity on MAPK-mediated luciferase activit... | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50069092![]() (CHEMBL3403508) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 951 | n/a | n/a | n/a | n/a |
RTI International Curated by ChEMBL | Assay Description Agonist activity at rat NTS2 overexpressed in CHO-k1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem Lett 25: 2060-4 (2015) Article DOI: 10.1016/j.bmcl.2015.03.083 BindingDB Entry DOI: 10.7270/Q2BZ67RD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor 2 (Rattus norvegicus) | BDBM50183341![]() (CHEMBL3817879) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.41E+3 | n/a | n/a | n/a | n/a |
RTI International Curated by ChEMBL | Assay Description Partial agonist activity at rat NTS2 receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay | Bioorg Med Chem 24: 3758-70 (2016) Article DOI: 10.1016/j.bmc.2016.06.018 BindingDB Entry DOI: 10.7270/Q2MS3VPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50444943![]() (CHEMBL3099773) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assay | Bioorg Med Chem Lett 24: 262-7 (2013) Article DOI: 10.1016/j.bmcl.2013.11.026 BindingDB Entry DOI: 10.7270/Q2NV9KQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50248035![]() ((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assay | Bioorg Med Chem Lett 24: 262-7 (2013) Article DOI: 10.1016/j.bmcl.2013.11.026 BindingDB Entry DOI: 10.7270/Q2NV9KQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342238![]() ((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-2-((S)-3-amino...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]NT from human NTS2 receptor expressed in HEK293 cells | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50159155![]() (CHEMBL3786852) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]NT(8 to 13 residues) from human NTSR2 expressed in HEK293 cell membranes | J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50342241![]() ((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-(2-(...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]NT from human NTS2 receptor expressed in HEK293 cells | J Med Chem 54: 2915-23 (2011) Article DOI: 10.1021/jm200006c BindingDB Entry DOI: 10.7270/Q2XK8FVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50048908![]() (CHEMBL415788) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.741 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co... | ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50509508![]() (CHEMBL4534768) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 0.955 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co... | ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50048908![]() (CHEMBL415788) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting | Bioorg Med Chem 25: 350-359 (2017) Article DOI: 10.1016/j.bmc.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DR2XG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50509510![]() (CHEMBL4564746) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co... | ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50048908![]() (CHEMBL415788) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]NT(8 to 13 residues) from human NTSR2 expressed in HEK293 cell membranes | J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50159156![]() (CHEMBL3786291) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H]NT(8 to 13 residues) from human NTSR2 expressed in HEK293 cell membranes | J Med Chem 59: 1925-45 (2016) Article DOI: 10.1021/acs.jmedchem.5b01495 BindingDB Entry DOI: 10.7270/Q2V69MGK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor (Homo sapiens (Human)) | BDBM50509513![]() (CHEMBL4537266) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation co... | ACS Med Chem Lett 11: 16-22 (2020) Article DOI: 10.1021/acsmedchemlett.9b00462 | |||||||||||
More data for this Ligand-Target Pair |
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