Found 139 hits Enz. Inhib. hit(s) with Target = 'Palmitoleoyl-protein carboxylesterase NOTUM' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144548
 (CHEMBL3760048)Show InChI InChI=1S/C12H6F2O2S2/c13-6-2-7-10-5(1-9(18-10)12(15)16)4-17-11(7)8(14)3-6/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144380
 (CHEMBL3759074)Show InChI InChI=1S/C14H10F2O2S/c1-6-4-9(15)8-3-2-7-5-10(14(17)18)19-13(7)11(8)12(6)16/h4-5H,2-3H2,1H3,(H,17,18) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144563
 (CHEMBL3758280)Show InChI InChI=1S/C14H13NOS/c1-8-6-9-7-12(14(15)16)17-13(9)11-5-3-2-4-10(8)11/h2-5,7-8H,6H2,1H3,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144566
 (CHEMBL3759297)Show InChI InChI=1S/C14H13NOS/c15-14(16)12-8-10-6-3-5-9-4-1-2-7-11(9)13(10)17-12/h1-2,4,7-8H,3,5-6H2,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144565
 (CHEMBL3758963)Show InChI InChI=1S/C15H15NOS/c1-15(2)8-9-7-12(14(16)17)18-13(9)10-5-3-4-6-11(10)15/h3-7H,8H2,1-2H3,(H2,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144380
 (CHEMBL3759074)Show InChI InChI=1S/C14H10F2O2S/c1-6-4-9(15)8-3-2-7-5-10(14(17)18)19-13(7)11(8)12(6)16/h4-5H,2-3H2,1H3,(H,17,18) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144571
 (CHEMBL3758275)Show InChI InChI=1S/C13H11NO2S/c14-13(15)11-7-8-5-6-16-10-4-2-1-3-9(10)12(8)17-11/h1-4,7H,5-6H2,(H2,14,15) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144549
 (CHEMBL3758291)Show InChI InChI=1S/C12H5F3O2S2/c13-6-2-5-10-4(1-7(19-10)12(16)17)3-18-11(5)9(15)8(6)14/h1-2H,3H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144560
 (CHEMBL3759069)Show InChI InChI=1S/C13H11NOS/c14-13(15)11-7-9-6-5-8-3-1-2-4-10(8)12(9)16-11/h1-4,7H,5-6H2,(H2,14,15) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144377
 (CHEMBL3759274)Show InChI InChI=1S/C14H11FO2S/c1-7-4-10-9(11(15)5-7)3-2-8-6-12(14(16)17)18-13(8)10/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50154398
 (CHEMBL3774864)Show InChI InChI=1S/C12H9F3N2O2S2/c13-12(14,15)10-7(5-1-2-5)8-9(21-10)11(17-4-16-8)20-3-6(18)19/h4-5H,1-3H2,(H,18,19) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells after 30 mins by TCF/LEF cell sensor assay |
Bioorg Med Chem Lett 26: 1525-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.021 BindingDB Entry DOI: 10.7270/Q26W9CZZ |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144574
 (CHEMBL3758560)Show InChI InChI=1S/C13H8Cl2O2S/c14-9-4-3-8-7(11(9)15)2-1-6-5-10(13(16)17)18-12(6)8/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144560
 (CHEMBL3759069)Show InChI InChI=1S/C13H11NOS/c14-13(15)11-7-9-6-5-8-3-1-2-4-10(8)12(9)16-11/h1-4,7H,5-6H2,(H2,14,15) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144578
 (CHEMBL3760062)Show InChI InChI=1S/C13H8ClFO2S/c14-10-5-7(15)4-9-8(10)2-1-6-3-11(13(16)17)18-12(6)9/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144562
 (CHEMBL3759323)Show InChI InChI=1S/C14H13NOS/c1-8-6-9-4-2-3-5-10(9)13-11(8)7-12(17-13)14(15)16/h2-5,7-8H,6H2,1H3,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144565
 (CHEMBL3758963)Show InChI InChI=1S/C15H15NOS/c1-15(2)8-9-7-12(14(16)17)18-13(9)10-5-3-4-6-11(10)15/h3-7H,8H2,1-2H3,(H2,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144571
 (CHEMBL3758275)Show InChI InChI=1S/C13H11NO2S/c14-13(15)11-7-8-5-6-16-10-4-2-1-3-9(10)12(8)17-11/h1-4,7H,5-6H2,(H2,14,15) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144563
 (CHEMBL3758280)Show InChI InChI=1S/C14H13NOS/c1-8-6-9-7-12(14(15)16)17-13(9)11-5-3-2-4-10(8)11/h2-5,7-8H,6H2,1H3,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144538
 (CHEMBL3758326)Show InChI InChI=1S/C12H6ClFO3S/c13-6-2-7-10(8(14)3-6)17-4-5-1-9(12(15)16)18-11(5)7/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144375
 (CHEMBL3759908)Show InChI InChI=1S/C13H8F2O2S/c14-9-4-3-8-7(11(9)15)2-1-6-5-10(13(16)17)18-12(6)8/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144583
 (CHEMBL3758279)Show InChI InChI=1S/C15H11NO2S/c1-8-2-4-11-10(12(8)7-16)5-3-9-6-13(15(17)18)19-14(9)11/h2,4,6H,3,5H2,1H3,(H,17,18) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144534
 (CHEMBL3759117)Show InChI InChI=1S/C13H9FO3S/c1-6-2-8-11(9(14)3-6)17-5-7-4-10(13(15)16)18-12(7)8/h2-4H,5H2,1H3,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144374
 (CHEMBL3759576)Show InChI InChI=1S/C14H11ClO2S/c1-7-4-10-9(11(15)5-7)3-2-8-6-12(14(16)17)18-13(8)10/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144566
 (CHEMBL3759297)Show InChI InChI=1S/C14H13NOS/c15-14(16)12-8-10-6-3-5-9-4-1-2-7-11(9)13(10)17-12/h1-2,4,7-8H,3,5-6H2,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144548
 (CHEMBL3760048)Show InChI InChI=1S/C12H6F2O2S2/c13-6-2-7-10-5(1-9(18-10)12(15)16)4-17-11(7)8(14)3-6/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144549
 (CHEMBL3758291)Show InChI InChI=1S/C12H5F3O2S2/c13-6-2-5-10-4(1-7(19-10)12(16)17)3-18-11(5)9(15)8(6)14/h1-2H,3H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144576
 (CHEMBL3760106)Show InChI InChI=1S/C13H8Cl2O2S/c14-7-4-9-8(10(15)5-7)2-1-6-3-11(13(16)17)18-12(6)9/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144585
 (CHEMBL3759044)Show InChI InChI=1S/C14H8FNO2S/c15-11-4-3-9-8(10(11)6-16)2-1-7-5-12(14(17)18)19-13(7)9/h3-5H,1-2H2,(H,17,18) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144574
 (CHEMBL3758560)Show InChI InChI=1S/C13H8Cl2O2S/c14-9-4-3-8-7(11(9)15)2-1-6-5-10(13(16)17)18-12(6)8/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50154397
 (CHEMBL3774760)Show InChI InChI=1S/C11H9ClN2O2S2/c12-10-7(5-1-2-5)8-9(18-10)11(14-4-13-8)17-3-6(15)16/h4-5H,1-3H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells after 30 mins by TCF/LEF cell sensor assay |
Bioorg Med Chem Lett 26: 1525-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.021 BindingDB Entry DOI: 10.7270/Q26W9CZZ |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144377
 (CHEMBL3759274)Show InChI InChI=1S/C14H11FO2S/c1-7-4-10-9(11(15)5-7)3-2-8-6-12(14(16)17)18-13(8)10/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144372
 (CHEMBL3758668)Show InChI InChI=1S/C14H11ClO3S/c1-18-10-5-4-9-8(12(10)15)3-2-7-6-11(14(16)17)19-13(7)9/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144578
 (CHEMBL3760062)Show InChI InChI=1S/C13H8ClFO2S/c14-10-5-7(15)4-9-8(10)2-1-6-3-11(13(16)17)18-12(6)9/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144539
 (CHEMBL3759027)Show InChI InChI=1S/C12H6ClFO3S/c13-8-3-6(14)2-7-10(8)17-4-5-1-9(12(15)16)18-11(5)7/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144543
 (CHEMBL3758454)Show InChI InChI=1S/C12H8O4S2/c13-12(14)9-5-7-6-18(15,16)10-4-2-1-3-8(10)11(7)17-9/h1-5H,6H2,(H,13,14) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144372
 (CHEMBL3758668)Show InChI InChI=1S/C14H11ClO3S/c1-18-10-5-4-9-8(12(10)15)3-2-7-6-11(14(16)17)19-13(7)9/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144533
 (CHEMBL3759406)Show InChI InChI=1S/C13H6FNO3S/c14-8-1-6(4-15)11-9(3-8)12-7(5-18-11)2-10(19-12)13(16)17/h1-3H,5H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144576
 (CHEMBL3760106)Show InChI InChI=1S/C13H8Cl2O2S/c14-7-4-9-8(10(15)5-7)2-1-6-3-11(13(16)17)18-12(6)9/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144539
 (CHEMBL3759027)Show InChI InChI=1S/C12H6ClFO3S/c13-8-3-6(14)2-7-10(8)17-4-5-1-9(12(15)16)18-11(5)7/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144534
 (CHEMBL3759117)Show InChI InChI=1S/C13H9FO3S/c1-6-2-8-11(9(14)3-6)17-5-7-4-10(13(15)16)18-12(7)8/h2-4H,5H2,1H3,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144374
 (CHEMBL3759576)Show InChI InChI=1S/C14H11ClO2S/c1-7-4-10-9(11(15)5-7)3-2-8-6-12(14(16)17)18-13(8)10/h4-6H,2-3H2,1H3,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144573
 (CHEMBL3759035)Show InChI InChI=1S/C15H11NO3S/c1-19-12-5-4-10-9(11(12)7-16)3-2-8-6-13(15(17)18)20-14(8)10/h4-6H,2-3H2,1H3,(H,17,18) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144540
 (CHEMBL3759995)Show InChI InChI=1S/C12H5F3O3S/c13-5-2-6-8(10(15)9(5)14)11-4(3-18-6)1-7(19-11)12(16)17/h1-2H,3H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144502
 (CHEMBL3758201)Show InChI InChI=1S/C12H6Cl2O3S/c13-7-2-1-6-10(9(7)14)17-4-5-3-8(12(15)16)18-11(5)6/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144547
 (CHEMBL3758520)Show InChI InChI=1S/C12H6F2O2S2/c13-6-1-2-7(14)11-9(6)10-5(4-17-11)3-8(18-10)12(15)16/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144562
 (CHEMBL3759323)Show InChI InChI=1S/C14H13NOS/c1-8-6-9-4-2-3-5-10(9)13-11(8)7-12(17-13)14(15)16/h2-5,7-8H,6H2,1H3,(H2,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144501
 (CHEMBL3758861)Show InChI InChI=1S/C12H6Cl2O3S/c13-6-2-7-10(8(14)3-6)17-4-5-1-9(12(15)16)18-11(5)7/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Homo sapiens (Human)) | BDBM50144502
 (CHEMBL3758201)Show InChI InChI=1S/C12H6Cl2O3S/c13-7-2-1-6-10(9(7)14)17-4-5-3-8(12(15)16)18-11(5)6/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 42 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50154398
 (CHEMBL3774864)Show InChI InChI=1S/C12H9F3N2O2S2/c13-12(14,15)10-7(5-1-2-5)8-9(21-10)11(17-4-16-8)20-3-6(18)19/h4-5H,1-3H2,(H,18,19) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells after 30 mins by TCF/LEF cell sensor assay |
Bioorg Med Chem Lett 26: 1525-8 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.021 BindingDB Entry DOI: 10.7270/Q26W9CZZ |
More data for this Ligand-Target Pair | |
Palmitoleoyl-protein carboxylesterase NOTUM
(Mus musculus) | BDBM50144581
 (CHEMBL3759700)Show InChI InChI=1S/C13H8ClFO2S/c14-11-7-2-1-6-5-10(13(16)17)18-12(6)8(7)3-4-9(11)15/h3-5H,1-2H2,(H,16,17) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a |
Lexicon Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of mouse notum pectinacetylesterase expressed in 293F cells by TCF/LEF CellSensor assay |
Bioorg Med Chem Lett 26: 1184-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.01.038 BindingDB Entry DOI: 10.7270/Q2QV3PBN |
More data for this Ligand-Target Pair | |