Compile Data Set for Download or QSAR

Found 225 hits Enz. Inhib. hit(s) with Target = 'Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476002 (CHEMBL217511) Show SMILES OC1=C2C(C3=C(COCC3=O)N=C2CO1)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C16H11BrFNO4/c17-8-3-7(1-2-9(8)18)13-14-10(4-22-6-12(14)20)19-11-5-23-16(21)15(11)13/h1-3,13,21H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.676	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475970 (CHEMBL426334) Show SMILES C[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(17(22)24-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-23-6-12(14)21/h2-4,7,13,22H,5-6H2,1H3/t7-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.912	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475995 (CHEMBL218564) Show SMILES CCC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475999 (CHEMBL214561) Show SMILES CC[C@@H]1CC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO3/c1-2-9-6-14(23)18-16(10-3-4-12(21)11(20)5-10)17-13(22-19(9)18)7-25-8-15(17)24/h3-5,9,16,23H,2,6-8H2,1H3/t9-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475981 (CHEMBL413532) Show SMILES C[C@H]1OCC(=O)C2=C1N=C1COC(O)=C1[C@@H]2c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(12(21)6-23-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-24-17(14)22/h2-4,7,13,22H,5-6H2,1H3/t7-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475993 (CHEMBL217810) Show SMILES C[C@@H]1N(C)C(=O)C2=C1NC1COCC(=O)C1[C@H]2c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H18BrFN2O3/c1-8-17-16(18(24)22(8)2)14(9-3-4-11(20)10(19)5-9)15-12(21-17)6-25-7-13(15)23/h3-5,8,12,14-15,21H,6-7H2,1-2H3/t8-,12?,14+,15?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475995 (CHEMBL218564) Show SMILES CCC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475953 (CHEMBL384564) Show SMILES CC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-2-13-17-16(18(23)25-13)14(8-3-4-10(20)9(19)5-8)15-11(21-17)6-24-7-12(15)22/h3-5,13-14,23H,2,6-7H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475995 (CHEMBL218564) Show SMILES CCC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475970 (CHEMBL426334) Show SMILES C[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(17(22)24-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-23-6-12(14)21/h2-4,7,13,22H,5-6H2,1H3/t7-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476020 (CHEMBL217847) Show SMILES CC[C@@H]1OC(O)=C2[C@@H](C3=C(COC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-2-11-15-14(17(22)24-11)12(7-3-4-9(19)8(18)5-7)13-10(20-15)6-23-16(13)21/h3-5,11-12,22H,2,6H2,1H3/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475971 (CHEMBL386363) Show SMILES COC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO5/c1-24-7-13-17-16(18(23)26-13)14(8-2-3-10(20)9(19)4-8)15-11(21-17)5-25-6-12(15)22/h2-4,13-14,23H,5-7H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475997 (CHEMBL386119) Show SMILES CC[C@@H]1OCC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-15-19-18(14(24)8-26-15)16(9-3-4-11(21)10(20)5-9)17-12(22-19)6-25-7-13(17)23/h3-5,15-16,24H,2,6-8H2,1H3/t15-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475973 (CHEMBL265269) Show SMILES CC[C@@H]1OC(O)=C2[C@@H](C3=C(COC(C)(C)C3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C20H19BrFNO4/c1-4-13-17-16(19(25)27-13)14(9-5-6-11(22)10(21)7-9)15-12(23-17)8-26-20(2,3)18(15)24/h5-7,13-14,25H,4,8H2,1-3H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475983 (CHEMBL216766) Show SMILES CC1(C)OCC2=NC3=C(C(C2=C1O)c1ccc(F)c(Br)c1)C(=O)COC3 Show InChI InChI=1S/C19H17BrFNO4/c1-19(2)18(24)17-13(7-26-19)22-12-6-25-8-14(23)16(12)15(17)9-3-4-11(21)10(20)5-9/h3-5,15,24H,6-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476011 (CHEMBL216284) Show SMILES CC[C@H]1OCC(=O)C2=C1N=C1COC(O)=C1[C@@H]2c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-2-13-17-16(12(22)7-24-13)14(8-3-4-10(20)9(19)5-8)15-11(21-17)6-25-18(15)23/h3-5,13-14,23H,2,6-7H2,1H3/t13-,14+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475982 (CHEMBL215375) Show SMILES CC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-2-13-17-16(18(23)25-13)14(8-3-4-10(20)9(19)5-8)15-11(21-17)6-24-7-12(15)22/h3-5,13-14,23H,2,6-7H2,1H3/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475997 (CHEMBL386119) Show SMILES CC[C@@H]1OCC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-15-19-18(14(24)8-26-15)16(9-3-4-11(21)10(20)5-9)17-12(22-19)6-25-7-13(17)23/h3-5,15-16,24H,2,6-8H2,1H3/t15-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50062397 (3N-cyanoimino(tert-pentylamino)methyl-3-pyridinami...) Show SMILES CCC(C)(C)NC(NC#N)=Nc1cccnc1 Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475972 (CHEMBL216546) Show SMILES COC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO5/c1-24-7-13-17-16(18(23)26-13)14(8-2-3-10(20)9(19)4-8)15-11(21-17)5-25-6-12(15)22/h2-4,13-14,23H,5-7H2,1H3/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475972 (CHEMBL216546) Show SMILES COC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO5/c1-24-7-13-17-16(18(23)26-13)14(8-2-3-10(20)9(19)4-8)15-11(21-17)5-25-6-12(15)22/h2-4,13-14,23H,5-7H2,1H3/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475977 (CHEMBL386582) Show SMILES CC1(C)OCC2=C(C(C3=C(O)OCC3=N2)c2ccc(F)c(Br)c2)C1=O Show InChI InChI=1S/C18H15BrFNO4/c1-18(2)16(22)14-12(7-25-18)21-11-6-24-17(23)15(11)13(14)8-3-4-10(20)9(19)5-8/h3-5,13,23H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475977 (CHEMBL386582) Show SMILES CC1(C)OCC2=C(C(C3=C(O)OCC3=N2)c2ccc(F)c(Br)c2)C1=O Show InChI InChI=1S/C18H15BrFNO4/c1-18(2)16(22)14-12(7-25-18)21-11-6-24-17(23)15(11)13(14)8-3-4-10(20)9(19)5-8/h3-5,13,23H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476013 (CHEMBL261996) Show SMILES CC1(C)OC(O)=C2C(C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-18(2)16-15(17(23)25-18)13(8-3-4-10(20)9(19)5-8)14-11(21-16)6-24-7-12(14)22/h3-5,13,23H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476003 (CHEMBL426160) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(I)c1 Show InChI InChI=1S/C19H17FINO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-10(20)11(21)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475961 (CHEMBL214841) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475966 (CHEMBL384576) Show SMILES CC(C)C[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C20H19BrFNO4/c1-9(2)5-15-19-18(20(25)27-15)16(10-3-4-12(22)11(21)6-10)17-13(23-19)7-26-8-14(17)24/h3-4,6,9,15-16,25H,5,7-8H2,1-2H3/t15-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475991 (CHEMBL320983) Show SMILES OC1=C2C(C3=C(COCC3=O)N=C2COC1)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c18-9-3-8(1-2-10(9)19)15-16-11(4-23-6-13(16)21)20-12-5-24-7-14(22)17(12)15/h1-3,15,21H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475961 (CHEMBL214841) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476004 (CHEMBL386323) Show SMILES CCCC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C20H19BrFNO4/c1-2-3-4-15-19-18(20(25)27-15)16(10-5-6-12(22)11(21)7-10)17-13(23-19)8-26-9-14(17)24/h5-7,15-16,25H,2-4,8-9H2,1H3/t15-,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475970 (CHEMBL426334) Show SMILES C[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(17(22)24-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-23-6-12(14)21/h2-4,7,13,22H,5-6H2,1H3/t7-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50044253 ((3R,4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxo-pyrrolidin...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H]([C@H]1O)N1CCCC1=O)C#N Show InChI InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475953 (CHEMBL384564) Show SMILES CC[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-2-13-17-16(18(23)25-13)14(8-3-4-10(20)9(19)5-8)15-11(21-17)6-24-7-12(15)22/h3-5,13-14,23H,2,6-7H2,1H3/t13-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476002 (CHEMBL217511) Show SMILES OC1=C2C(C3=C(COCC3=O)N=C2CO1)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C16H11BrFNO4/c17-8-3-7(1-2-9(8)18)13-14-10(4-22-6-12(14)20)19-11-5-23-16(21)15(11)13/h1-3,13,21H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476002 (CHEMBL217511) Show SMILES OC1=C2C(C3=C(COCC3=O)N=C2CO1)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C16H11BrFNO4/c17-8-3-7(1-2-9(8)18)13-14-10(4-22-6-12(14)20)19-11-5-23-16(21)15(11)13/h1-3,13,21H,4-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475970 (CHEMBL426334) Show SMILES C[C@@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(17(22)24-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-23-6-12(14)21/h2-4,7,13,22H,5-6H2,1H3/t7-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50062397 (3N-cyanoimino(tert-pentylamino)methyl-3-pyridinami...) Show SMILES CCC(C)(C)NC(NC#N)=Nc1cccnc1 Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475954 (CHEMBL216256) Show SMILES CC[C@H]1OCC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H17Cl2NO4/c1-2-15-19-18(14(24)8-26-15)16(9-3-4-10(20)11(21)5-9)17-12(22-19)6-25-7-13(17)23/h3-5,15-16,24H,2,6-8H2,1H3/t15-,16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contraction				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476014 (CHEMBL3138600) Show SMILES C[C@@H]1OC(=O)C2=C1NC1=C([C@H]2c2ccc(F)c(Br)c2)S(=O)(=O)CCC1 Show InChI InChI=1S/C17H15BrFNO4S/c1-8-15-14(17(21)24-8)13(9-4-5-11(19)10(18)7-9)16-12(20-15)3-2-6-25(16,22)23/h4-5,7-8,13,20H,2-3,6H2,1H3/t8-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476010 (CHEMBL412838) Show SMILES CC[C@@H]1OC(O)=C2[C@@H](C3=C(CCCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C19H17BrFNO3/c1-2-14-18-17(19(24)25-14)15(9-6-7-11(21)10(20)8-9)16-12(22-18)4-3-5-13(16)23/h6-8,14-15,24H,2-5H2,1H3/t14-,15+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475992 (CHEMBL2112487) Show SMILES Fc1ccc(cc1Br)[C@H]1C2=C(COC2=O)NC2=C1C(=O)COC2 Show InChI InChI=1S/C16H11BrFNO4/c17-8-3-7(1-2-9(8)18)13-14-10(4-22-6-12(14)20)19-11-5-23-16(21)15(11)13/h1-3,13,19H,4-6H2/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476000 (CHEMBL215996) Show SMILES C[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(17(22)24-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-23-6-12(14)21/h2-4,7,13,22H,5-6H2,1H3/t7-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475959 (CHEMBL214566) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C19H17ClFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475987 (CHEMBL386126) Show SMILES C[C@@H]1OCC2=C([C@@H](C3=C(O)OCC3=N2)c2ccc(F)c(Br)c2)C1=O Show InChI InChI=1S/C17H13BrFNO4/c1-7-16(21)14-11(5-23-7)20-12-6-24-17(22)15(12)13(14)8-2-3-10(19)9(18)4-8/h2-4,7,13,22H,5-6H2,1H3/t7-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475958 (CHEMBL424726) Show SMILES CC[C@H]1OC(O)=C2[C@@H](C3=C(COC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-2-11-15-14(17(22)24-11)12(7-3-4-9(19)8(18)5-7)13-10(20-15)6-23-16(13)21/h3-5,11-12,22H,2,6H2,1H3/t11-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476003 (CHEMBL426160) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(I)c1 Show InChI InChI=1S/C19H17FINO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-10(20)11(21)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50062397 (3N-cyanoimino(tert-pentylamino)methyl-3-pyridinami...) Show SMILES CCC(C)(C)NC(NC#N)=Nc1cccnc1 Show InChI InChI=1S/C12H17N5/c1-4-12(2,3)17-11(15-9-13)16-10-6-5-7-14-8-10/h5-8H,4H2,1-3H3,(H2,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusor				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475959 (CHEMBL214566) Show SMILES CCC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C19H17ClFNO4/c1-2-3-14-18-17(19(24)26-14)15(9-4-5-11(21)10(20)6-9)16-12(22-18)7-25-8-13(16)23/h4-6,14-15,24H,2-3,7-8H2,1H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50475982 (CHEMBL215375) Show SMILES CC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1 Show InChI InChI=1S/C18H15BrFNO4/c1-2-13-17-16(18(23)25-13)14(8-3-4-10(20)9(19)5-8)15-11(21-17)6-24-7-12(15)22/h3-5,13-14,23H,2,6-7H2,1H3/t13-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2 (Homo sapiens (Human))	BDBM50476005 (CHEMBL385908) Show SMILES C[C@@H]1OCC(=O)C2=C1N=C1COC(O)=C1[C@@H]2c1ccc(F)c(Br)c1 Show InChI InChI=1S/C17H13BrFNO4/c1-7-16-15(12(21)6-23-7)13(8-2-3-10(19)9(18)4-8)14-11(20-16)5-24-17(14)22/h2-4,7,13,22H,5-6H2,1H3/t7-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay				J Med Chem 49: 6869-87 (2006) Article DOI: 10.1021/jm060549u BindingDB Entry DOI: 10.7270/Q2X069S9
					More data for this Ligand-Target Pair

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