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Compile Data Set for Download or QSAR

Found 96 hits Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 34'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 34


(Mus musculus)
BDBM50177130
PNG
(CHEMBL3815069)
Show SMILES Cc1ccc(Oc2cccc(COc3ccccc3CCC(=O)OC[C@H]3OCCC[C@H]3OP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1
Show InChI InChI=1S/C32H38NO11P/c1-22-11-14-25(15-12-22)43-26-8-4-6-23(18-26)19-40-28-9-3-2-7-24(28)13-16-31(34)41-21-30-29(10-5-17-39-30)44-45(37,38)42-20-27(33)32(35)36/h2-4,6-9,11-12,14-15,18,27,29-30H,5,10,13,16-17,19-21,33H2,1H3,(H,35,36)(H,37,38)/t27-,29+,30+/m0/s1
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n/an/an/an/a 35n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177140
PNG
(CHEMBL3814525)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccc(Cl)cc2)c1)C(O)=O
Show InChI InChI=1S/C31H35ClNO11P/c32-23-11-13-24(14-12-23)43-25-7-3-5-21(17-25)18-40-27-8-2-1-6-22(27)10-15-30(34)41-20-29-28(9-4-16-39-29)44-45(37,38)42-19-26(33)31(35)36/h1-3,5-8,11-14,17,26,28-29H,4,9-10,15-16,18-20,33H2,(H,35,36)(H,37,38)/t26-,28+,29+/m0/s1
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n/an/an/an/a 36n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177130
PNG
(CHEMBL3815069)
Show SMILES Cc1ccc(Oc2cccc(COc3ccccc3CCC(=O)OC[C@H]3OCCC[C@H]3OP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1
Show InChI InChI=1S/C32H38NO11P/c1-22-11-14-25(15-12-22)43-26-8-4-6-23(18-26)19-40-28-9-3-2-7-24(28)13-16-31(34)41-21-30-29(10-5-17-39-30)44-45(37,38)42-20-27(33)32(35)36/h2-4,6-9,11-12,14-15,18,27,29-30H,5,10,13,16-17,19-21,33H2,1H3,(H,35,36)(H,37,38)/t27-,29+,30+/m0/s1
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n/an/an/an/a 36n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177140
PNG
(CHEMBL3814525)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccc(Cl)cc2)c1)C(O)=O
Show InChI InChI=1S/C31H35ClNO11P/c32-23-11-13-24(14-12-23)43-25-7-3-5-21(17-25)18-40-27-8-2-1-6-22(27)10-15-30(34)41-20-29-28(9-4-16-39-29)44-45(37,38)42-19-26(33)31(35)36/h1-3,5-8,11-14,17,26,28-29H,4,9-10,15-16,18-20,33H2,(H,35,36)(H,37,38)/t26-,28+,29+/m0/s1
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n/an/an/an/a 37n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177132
PNG
(CHEMBL3814818)
Show SMILES Cc1ccc(Oc2cccc(COc3ccccc3CCC(=O)O[C@@H]3CCCO[C@@H]3COP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1
Show InChI InChI=1S/C32H38NO11P/c1-22-11-14-25(15-12-22)43-26-8-4-6-23(18-26)19-40-28-9-3-2-7-24(28)13-16-31(34)44-29-10-5-17-39-30(29)21-42-45(37,38)41-20-27(33)32(35)36/h2-4,6-9,11-12,14-15,18,27,29-30H,5,10,13,16-17,19-21,33H2,1H3,(H,35,36)(H,37,38)/t27-,29+,30+/m0/s1
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n/an/an/an/a 76n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177132
PNG
(CHEMBL3814818)
Show SMILES Cc1ccc(Oc2cccc(COc3ccccc3CCC(=O)O[C@@H]3CCCO[C@@H]3COP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1
Show InChI InChI=1S/C32H38NO11P/c1-22-11-14-25(15-12-22)43-26-8-4-6-23(18-26)19-40-28-9-3-2-7-24(28)13-16-31(34)44-29-10-5-17-39-30(29)21-42-45(37,38)41-20-27(33)32(35)36/h2-4,6-9,11-12,14-15,18,27,29-30H,5,10,13,16-17,19-21,33H2,1H3,(H,35,36)(H,37,38)/t27-,29+,30+/m0/s1
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n/an/an/an/a 77n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177122
PNG
(CHEMBL3814362)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1OCCCC1OP(O)(=O)OCC(N)C(O)=O
Show InChI InChI=1S/C27H50NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)35-22-25-24(18-17-20-34-25)37-38(32,33)36-21-23(28)27(30)31/h9-10,23-25H,2-8,11-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24-,25+/m0/s1
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n/an/an/an/a 100n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177118
PNG
(CHEMBL3814763)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCCC[C@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H48NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,14-15,24,26-27H,2-9,12-13,16-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26+,27+/m0/s1
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n/an/an/an/a 110n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177118
PNG
(CHEMBL3814763)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCCC[C@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H48NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,14-15,24,26-27H,2-9,12-13,16-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26+,27+/m0/s1
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n/an/an/an/a 110n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177131
PNG
(CHEMBL3815141)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCCC[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccc(Cl)cc2)c1)C(O)=O
Show InChI InChI=1S/C31H35ClNO11P/c32-23-11-13-24(14-12-23)43-25-7-3-5-21(17-25)18-40-27-8-2-1-6-22(27)10-15-30(34)44-28-9-4-16-39-29(28)20-42-45(37,38)41-19-26(33)31(35)36/h1-3,5-8,11-14,17,26,28-29H,4,9-10,15-16,18-20,33H2,(H,35,36)(H,37,38)/t26-,28+,29+/m0/s1
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n/an/an/an/a 117n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177131
PNG
(CHEMBL3815141)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCCC[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccc(Cl)cc2)c1)C(O)=O
Show InChI InChI=1S/C31H35ClNO11P/c32-23-11-13-24(14-12-23)43-25-7-3-5-21(17-25)18-40-27-8-2-1-6-22(27)10-15-30(34)44-28-9-4-16-39-29(28)20-42-45(37,38)41-19-26(33)31(35)36/h1-3,5-8,11-14,17,26,28-29H,4,9-10,15-16,18-20,33H2,(H,35,36)(H,37,38)/t26-,28+,29+/m0/s1
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n/an/an/an/a 120n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177117
PNG
(CHEMBL3814092)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 138n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177117
PNG
(CHEMBL3814092)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 140n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096361
PNG
(CHEMBL3577175)
Show SMILES CCCCCCCCCCCCCCCOc1cccc(CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O)c1
Show InChI InChI=1S/C30H52NO10P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-20-38-27-17-15-16-25(21-27)18-19-29(33)39-22-26(32)23-40-42(36,37)41-24-28(31)30(34)35/h15-17,21,26,28,32H,2-14,18-20,22-24,31H2,1H3,(H,34,35)(H,36,37)/t26-,28+/m1/s1
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n/an/an/an/a 158n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096361
PNG
(CHEMBL3577175)
Show SMILES CCCCCCCCCCCCCCCOc1cccc(CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O)c1
Show InChI InChI=1S/C30H52NO10P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-20-38-27-17-15-16-25(21-27)18-19-29(33)39-22-26(32)23-40-42(36,37)41-24-28(31)30(34)35/h15-17,21,26,28,32H,2-14,18-20,22-24,31H2,1H3,(H,34,35)(H,36,37)/t26-,28+/m1/s1
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n/an/an/an/a 160n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177124
PNG
(CHEMBL3814643)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCC=C[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-40-44(36,37)41-21-29-28(14-7-17-38-29)43-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 180n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Mus musculus)
BDBM50177124
PNG
(CHEMBL3814643)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCC=C[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-40-44(36,37)41-21-29-28(14-7-17-38-29)43-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 182n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177138
PNG
(CHEMBL3813950)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCCC[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-40-44(36,37)41-21-29-28(14-7-17-38-29)43-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 186n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177138
PNG
(CHEMBL3813950)
Show SMILES N[C@@H](COP(O)(=O)OC[C@H]1OCCC[C@H]1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-40-44(36,37)41-21-29-28(14-7-17-38-29)43-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 190n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177122
PNG
(CHEMBL3814362)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1OCCCC1OP(O)(=O)OCC(N)C(O)=O
Show InChI InChI=1S/C27H50NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)35-22-25-24(18-17-20-34-25)37-38(32,33)36-21-23(28)27(30)31/h9-10,23-25H,2-8,11-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24-,25+/m0/s1
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n/an/an/an/a 209n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177122
PNG
(CHEMBL3814362)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1OCCCC1OP(O)(=O)OCC(N)C(O)=O
Show InChI InChI=1S/C27H50NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)35-22-25-24(18-17-20-34-25)37-38(32,33)36-21-23(28)27(30)31/h9-10,23-25H,2-8,11-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24-,25+/m0/s1
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n/an/an/an/a 210n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096360
PNG
(CHEMBL3577174)
Show SMILES CCCCCCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C30H52NO10P/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21-38-28-18-15-14-17-25(28)19-20-29(33)39-22-26(32)23-40-42(36,37)41-24-27(31)30(34)35/h14-15,17-18,26-27,32H,2-13,16,19-24,31H2,1H3,(H,34,35)(H,36,37)/t26-,27+/m1/s1
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n/an/an/an/a 234n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096360
PNG
(CHEMBL3577174)
Show SMILES CCCCCCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C30H52NO10P/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21-38-28-18-15-14-17-25(28)19-20-29(33)39-22-26(32)23-40-42(36,37)41-24-27(31)30(34)35/h14-15,17-18,26-27,32H,2-13,16,19-24,31H2,1H3,(H,34,35)(H,36,37)/t26-,27+/m1/s1
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n/an/an/an/a 240n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Mus musculus)
BDBM50096349
PNG
(CHEBI:52649 | CHEMBL1742484)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H16FN3O/c1-15-6-2-3-8-20(15)26-21(12-10-17-7-4-5-13-24-17)25-19-11-9-16(23)14-18(19)22(26)27/h2-14H,1H3/b12-10+
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n/an/an/an/a 240n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50096349
PNG
(CHEBI:52649 | CHEMBL1742484)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H16FN3O/c1-15-6-2-3-8-20(15)26-21(12-10-17-7-4-5-13-24-17)25-19-11-9-16(23)14-18(19)22(26)27/h2-14H,1H3/b12-10+
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n/an/an/an/a 240n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096353
PNG
(CHEMBL3577145)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H44NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-21(25)30-16-19(24)17-31-33(28,29)32-18-20(23)22(26)27/h19-20,24H,2-18,23H2,1H3,(H,26,27)(H,28,29)/t19-,20+/m1/s1
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n/an/an/an/a 288n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096353
PNG
(CHEMBL3577145)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H44NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-21(25)30-16-19(24)17-31-33(28,29)32-18-20(23)22(26)27/h19-20,24H,2-18,23H2,1H3,(H,26,27)(H,28,29)/t19-,20+/m1/s1
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n/an/an/an/a 290n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096351
PNG
(CHEMBL3577140)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC(C)(C)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C26H50NO8P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24(28)33-21-26(2,3)22-35-36(31,32)34-20-23(27)25(29)30/h11-12,23H,4-10,13-22,27H2,1-3H3,(H,29,30)(H,31,32)/b12-11-/t23-/m0/s1
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n/an/an/an/a 316n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096351
PNG
(CHEMBL3577140)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC(C)(C)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C26H50NO8P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24(28)33-21-26(2,3)22-35-36(31,32)34-20-23(27)25(29)30/h11-12,23H,4-10,13-22,27H2,1-3H3,(H,29,30)(H,31,32)/b12-11-/t23-/m0/s1
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n/an/an/an/a 320n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177120
PNG
(CHEMBL3813773)
Show SMILES N[C@@H](COP(O)(=O)O[C@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28-,29+/m0/s1
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n/an/an/an/a 340n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177120
PNG
(CHEMBL3813773)
Show SMILES N[C@@H](COP(O)(=O)O[C@H]1CCCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H36NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-6,8-13,18,26,28-29H,7,14-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28-,29+/m0/s1
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n/an/an/an/a 347n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096350
PNG
(CHEMBL3577138)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22-/m0/s1
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n/an/an/an/a 410n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096350
PNG
(CHEMBL3577138)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22-/m0/s1
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n/an/an/an/a 417n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096359
PNG
(CHEMBL3577171)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C26H44NO10P/c1-2-3-4-5-6-7-8-9-12-17-34-24-14-11-10-13-21(24)15-16-25(29)35-18-22(28)19-36-38(32,33)37-20-23(27)26(30)31/h10-11,13-14,22-23,28H,2-9,12,15-20,27H2,1H3,(H,30,31)(H,32,33)/t22-,23+/m1/s1
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The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177151
PNG
(CHEMBL3814147)
Show SMILES N[C@@H](COP(O)(=O)O[C@H]1C=CCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28-,29+/m0/s1
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n/an/an/an/a 460n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096359
PNG
(CHEMBL3577171)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C26H44NO10P/c1-2-3-4-5-6-7-8-9-12-17-34-24-14-11-10-13-21(24)15-16-25(29)35-18-22(28)19-36-38(32,33)37-20-23(27)26(30)31/h10-11,13-14,22-23,28H,2-9,12,15-20,27H2,1H3,(H,30,31)(H,32,33)/t22-,23+/m1/s1
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The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177151
PNG
(CHEMBL3814147)
Show SMILES N[C@@H](COP(O)(=O)O[C@H]1C=CCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28-,29+/m0/s1
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n/an/an/an/a 468n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177142
PNG
(CHEMBL3813751)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCC=C[C@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H46NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,13-16,24,26-27H,2-9,12,17-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26+,27+/m0/s1
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n/an/an/an/a 510n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177142
PNG
(CHEMBL3813751)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCC=C[C@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H46NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,13-16,24,26-27H,2-9,12,17-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26+,27+/m0/s1
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n/an/an/an/a 513n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096349
PNG
(CHEBI:52649 | CHEMBL1742484)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H16FN3O/c1-15-6-2-3-8-20(15)26-21(12-10-17-7-4-5-13-24-17)25-19-11-9-16(23)14-18(19)22(26)27/h2-14H,1H3/b12-10+
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n/an/an/an/a 550n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096349
PNG
(CHEBI:52649 | CHEMBL1742484)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C22H16FN3O/c1-15-6-2-3-8-20(15)26-21(12-10-17-7-4-5-13-24-17)25-19-11-9-16(23)14-18(19)22(26)27/h2-14H,1H3/b12-10+
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n/an/an/an/a 550n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177127
PNG
(CHEMBL3813812)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)O[C@@H]1C=CCO[C@@H]1COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C27H48NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)37-24-18-17-20-34-25(24)22-36-38(32,33)35-21-23(28)27(30)31/h9-10,17-18,23-25H,2-8,11-16,19-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24+,25+/m0/s1
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n/an/an/an/a 550n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177127
PNG
(CHEMBL3813812)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)O[C@@H]1C=CCO[C@@H]1COP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C27H48NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-26(29)37-24-18-17-20-34-25(24)22-36-38(32,33)35-21-23(28)27(30)31/h9-10,17-18,23-25H,2-8,11-16,19-22,28H2,1H3,(H,30,31)(H,32,33)/b10-9-/t23-,24+,25+/m0/s1
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n/an/an/an/a 560n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177143
PNG
(CHEMBL3814235)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1C=CCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 600n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177143
PNG
(CHEMBL3814235)
Show SMILES N[C@@H](COP(O)(=O)O[C@@H]1C=CCO[C@@H]1COC(=O)CCc1ccccc1OCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C31H34NO11P/c32-26(31(34)35)20-41-44(36,37)43-28-14-7-17-38-29(28)21-40-30(33)16-15-23-9-4-5-13-27(23)39-19-22-8-6-12-25(18-22)42-24-10-2-1-3-11-24/h1-14,18,26,28-29H,15-17,19-21,32H2,(H,34,35)(H,36,37)/t26-,28+,29+/m0/s1
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n/an/an/an/a 603n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177121
PNG
(CHEMBL3814009)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCCC[C@@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H48NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,14-15,24,26-27H,2-9,12-13,16-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26-,27+/m0/s1
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n/an/an/an/a 640n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177121
PNG
(CHEMBL3814009)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OC[C@H]1OCCC[C@@H]1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C29H48NO10P/c1-2-3-4-5-6-7-8-9-12-19-36-25-15-11-10-14-23(25)17-18-28(31)38-22-27-26(16-13-20-37-27)40-41(34,35)39-21-24(30)29(32)33/h10-11,14-15,24,26-27H,2-9,12-13,16-22,30H2,1H3,(H,32,33)(H,34,35)/t24-,26-,27+/m0/s1
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n/an/an/an/a 646n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Homo sapiens)
BDBM50096357
PNG
(CHEMBL3577151)
Show SMILES CCCCCCCCCCCCCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C20H40NO8P/c1-2-3-4-5-6-7-8-9-10-11-12-14-19(22)27-15-13-16-28-30(25,26)29-17-18(21)20(23)24/h18H,2-17,21H2,1H3,(H,23,24)(H,25,26)/t18-/m0/s1
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n/an/an/an/a 700n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay


J Med Chem 58: 4204-19 (2015)


Article DOI: 10.1021/jm5020082
BindingDB Entry DOI: 10.7270/Q2Q81FTD
More data for this
Ligand-Target Pair
G protein-coupled receptor 34


(Mus musculus)
BDBM50177123
PNG
(CHEMBL3815090)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OCc1ccccc1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C30H44NO9P/c1-2-3-4-5-6-7-8-9-14-21-37-27-17-12-10-15-24(27)19-20-29(32)38-22-25-16-11-13-18-28(25)40-41(35,36)39-23-26(31)30(33)34/h10-13,15-18,26H,2-9,14,19-23,31H2,1H3,(H,33,34)(H,35,36)/t26-/m0/s1
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n/an/an/an/a 700n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
Probable G-protein coupled receptor 34


(Mus musculus)
BDBM50177123
PNG
(CHEMBL3815090)
Show SMILES CCCCCCCCCCCOc1ccccc1CCC(=O)OCc1ccccc1OP(O)(=O)OC[C@H](N)C(O)=O
Show InChI InChI=1S/C30H44NO9P/c1-2-3-4-5-6-7-8-9-14-21-37-27-17-12-10-15-24(27)19-20-29(32)38-22-25-16-11-13-18-28(25)40-41(35,36)39-23-26(31)30(33)34/h10-13,15-18,26H,2-9,14,19-23,31H2,1H3,(H,33,34)(H,35,36)/t26-/m0/s1
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n/an/an/an/a 708n/an/an/an/a



The University of Tokyo

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR34 expressed in HEK293A cells cotransfected with chimeric Galphaq/il after 1.5 hrs by alkaline phosphatase tagged-TGFalp...


J Med Chem 59: 3750-76 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01925
BindingDB Entry DOI: 10.7270/Q2542QHQ
More data for this
Ligand-Target Pair
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