Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with Target = 'Purinergic receptor P2Y11'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118217 (ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE | ATP-g...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O12P3S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at P2Y11 receptor expressed in 1321N1 cells assessed as cytosolic calcium level				J Med Chem 50: 5600-7 (2007) Article DOI: 10.1021/jm070043r BindingDB Entry DOI: 10.7270/Q2445Q7Z
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50435008 (CHEMBL2386496) Show SMILES B[P@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O Show InChI InChI=1S/C11H16BCl3N5O11P3/c12-34(28,31-33(26,27)11(14,15)32(23,24)25)29-1-3-5(21)6(22)9(30-3)20-2-17-4-7(16)18-10(13)19-8(4)20/h2-3,5-6,9,21-22H,1,12H2,(H,26,27)(H2,16,18,19)(H2,23,24,25)/t3-,5-,6-,9-,34+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50477240 (8-CARBOXY-ISO-IANTHERAN A) Show SMILES [Na+].[Na+].OC(=O)c1c(oc2c(Br)cc(\C=C(/OS([O-])(=O)=O)\C(\OS([O-])(=O)=O)=C\c3cc(Br)c4oc(cc4c3)-c3ccc(O)c(Br)c3)cc12)-c1ccc(O)c(Br)c1 Show InChI InChI=1S/C33H18Br4O14S2/c34-20-11-16(1-3-24(20)38)26-13-18-5-14(7-22(36)30(18)48-26)9-27(50-52(42,43)44)28(51-53(45,46)47)10-15-6-19-29(33(40)41)31(49-32(19)23(37)8-15)17-2-4-25(39)21(35)12-17/h1-13,38-39H,(H,40,41)(H,42,43,44)(H,45,46,47)/p-2/b27-9-,28-10-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at P2Y11 receptor expressed in 1321N1 cells assessed as cytosolic calcium level				J Med Chem 50: 5600-7 (2007) Article DOI: 10.1021/jm070043r BindingDB Entry DOI: 10.7270/Q2445Q7Z
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131063 (CHEMBL3634183) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14ClN5O9P2S/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(24-9)1-23-27(22,28)25-26(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,28)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-,27?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Inhibitory concentration against Cathepsin B activity				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131061 (CHEMBL3634185) Show SMILES CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]3O)c2n1 Show InChI InChI=1S/C11H17N5O9P2S2/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(24-10)2-23-26(19,20)25-27(21,22)28/h3-4,6-7,10,17-18H,2H2,1H3,(H,19,20)(H2,12,14,15)(H2,21,22,28)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50019292 (CHEMBL3289393) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=S)OP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C11H18N5O11P3S/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(26-11)1-25-30(24,31)27-29(22,23)4-28(19,20)21/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H,24,31)(H2,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-,30-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human P2Y11 receptor expressed in human 1321N1 cells assessed as increase of intracellular calcium level after 30 mins using fura...				J Med Chem 57: 4677-91 (2014) Article DOI: 10.1021/jm500196c BindingDB Entry DOI: 10.7270/Q2QN68C6
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131064 (CHEMBL3634182) Show SMILES CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 Show InChI InChI=1S/C11H17N5O9P2S2/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(24-10)2-23-27(22,28)25-26(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,28)(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-,27?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50435010 (CHEMBL2386492) Show SMILES B[P@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12)OP(O)(O)=O Show InChI InChI=1S/C10H15BClN5O9P2/c11-27(20,26-28(21,22)23)24-1-3-5(18)6(19)9(25-3)17-2-14-4-7(13)15-10(12)16-8(4)17/h2-3,5-6,9,18-19H,1,11H2,(H2,13,15,16)(H2,21,22,23)/t3-,5-,6-,9-,27+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131060 (CHEMBL3634186) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14ClN5O9P2S/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(24-9)1-23-26(19,20)25-27(21,22)28/h2-3,5-6,9,17-18H,1H2,(H,19,20)(H2,12,14,15)(H2,21,22,28)/t3-,5-,6-,9-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131062 (CHEMBL3634184) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15ClN5O12P3S/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(26-9)1-25-31(24,32)28-30(22,23)27-29(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,32)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-,31?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-2 binding				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50477239 (ISO-IANTHERAN A) Show SMILES [Na+].[Na+].Oc1ccc(cc1Br)-c1cc2cc(\C=C(/OS([O-])(=O)=O)\C(\OS([O-])(=O)=O)=C\c3cc(Br)c4oc(cc4c3)-c3ccc(O)c(Br)c3)cc(Br)c2o1 Show InChI InChI=1S/C32H18Br4O12S2/c33-21-11-17(1-3-25(21)37)27-13-19-5-15(7-23(35)31(19)45-27)9-29(47-49(39,40)41)30(48-50(42,43)44)10-16-6-20-14-28(46-32(20)24(36)8-16)18-2-4-26(38)22(34)12-18/h1-14,37-38H,(H,39,40,41)(H,42,43,44)/p-2/b29-9-,30-10-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at P2Y11 receptor expressed in 1321N1 cells assessed as cytosolic calcium level				J Med Chem 50: 5600-7 (2007) Article DOI: 10.1021/jm070043r BindingDB Entry DOI: 10.7270/Q2445Q7Z
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50435009 (CHEMBL2386495) Show SMILES B[P@@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O Show InChI InChI=1S/C11H16BCl3N5O11P3/c12-34(28,31-33(26,27)11(14,15)32(23,24)25)29-1-3-5(21)6(22)9(30-3)20-2-17-4-7(16)18-10(13)19-8(4)20/h2-3,5-6,9,21-22H,1,12H2,(H,26,27)(H2,16,18,19)(H2,23,24,25)/t3-,5-,6-,9-,34-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131063 (CHEMBL3634183) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14ClN5O9P2S/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(24-9)1-23-27(22,28)25-26(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,28)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-,27?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50435012 (CHEMBL2386490) Show SMILES CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@H](O)[C@H]3OC(=O)c3ccccc3)c2n1 Show InChI InChI=1S/C18H21N5O11P2S/c1-37-18-21-14(19)11-15(22-18)23(8-20-11)16-13(33-17(25)9-5-3-2-4-6-9)12(24)10(32-16)7-31-36(29,30)34-35(26,27)28/h2-6,8,10,12-13,16,24H,7H2,1H3,(H,29,30)(H2,19,21,22)(H2,26,27,28)/t10-,12+,13-,16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118223 (AR-C67085 | Adenosine triphosphate derivative | CH...) Show SMILES CCCSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 Show InChI InChI=1S/C14H22Cl2N5O12P3S/c1-2-3-37-13-19-10(17)7-11(20-13)21(5-18-7)12-9(23)8(22)6(32-12)4-31-36(29,30)33-35(27,28)14(15,16)34(24,25)26/h5-6,8-9,12,22-23H,2-4H2,1H3,(H,27,28)(H,29,30)(H2,17,19,20)(H2,24,25,26)/t6-,8-,9-,12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50368125 (ADENOSINE DIPHOSPHATE | ADP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50368125 (ADENOSINE DIPHOSPHATE | ADP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50398070 (CHEMBL2181938) Show SMILES [BH3-][P@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP([O-])([O-])=O Show InChI InChI=1S/C10H17BN5O9P2/c11-26(19,25-27(20,21)22)23-1-4-6(17)7(18)10(24-4)16-3-15-5-8(12)13-2-14-9(5)16/h2-4,6-7,10,17-18H,1H2,11H3,(H2,12,13,14)(H2,20,21,22)/q-1/p-2/t4-,6-,7-,10-,26+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118217 (ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE | ATP-g...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O12P3S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131064 (CHEMBL3634182) Show SMILES CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 Show InChI InChI=1S/C11H17N5O9P2S2/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(24-10)2-23-27(22,28)25-26(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,28)(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-,27?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM2 (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...				J Med Chem 53: 8485-97 (2010) Article DOI: 10.1021/jm100597c BindingDB Entry DOI: 10.7270/Q22V2GF7
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50435011 (CHEMBL2386491) Show SMILES [BH3-][P@@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12)OP(O)(O)=O Show InChI InChI=1S/C10H16BClN5O9P2/c11-27(20,26-28(21,22)23)24-1-3-5(18)6(19)9(25-3)17-2-14-4-7(13)15-10(12)16-8(4)17/h2-3,5-6,9,18-19H,1H2,11H3,(H2,13,15,16)(H2,21,22,23)/q-1/t3-,5-,6-,9-,27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.68E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131059 (CHEMBL575257) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-26(21,27)24-25(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,27)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-,26?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-2 binding				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50366480 (ADENOSINE TRIPHOSPHATE | ATP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50366480 (ADENOSINE TRIPHOSPHATE | ATP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at human GFP-tagged P2Y11R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluoresc...				J Med Chem 56: 4938-52 (2013) Article DOI: 10.1021/jm400197m BindingDB Entry DOI: 10.7270/Q2Q52R0Q
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118219 (Bz-ATP | CHEMBL339386) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1OC(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H24N5O14P3/c24-20-17-21(26-11-25-20)28(12-27-17)22-19(40-23(30)15-8-6-14(7-9-15)13-4-2-1-3-5-13)18(29)16(39-22)10-38-44(34,35)42-45(36,37)41-43(31,32)33/h1-9,11-12,16,18-19,22,29H,10H2,(H,34,35)(H,36,37)(H2,24,25,26)(H2,31,32,33)/t16-,18-,19-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131059 (CHEMBL575257) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-26(21,27)24-25(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,27)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-,26?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118233 (2'-deoxyadenosine 5'-(tetrahydrogen triphosphate) ...) Show SMILES Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 Show InChI InChI=1S/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50131062 (CHEMBL3634184) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15ClN5O12P3S/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(26-9)1-25-31(24,32)28-30(22,23)27-29(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,32)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-,31?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50347445 (CHEMBL1802094) Show SMILES [BH3-]P(=O)(OP([O-])(=O)CP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP([O-])(=O)CP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C22H35BN10O19P5/c23-57(46,51-55(42,43)7-53(38,39)47-1-9-13(34)15(36)21(49-9)32-5-30-11-17(24)26-3-28-19(11)32)52-56(44,45)8-54(40,41)48-2-10-14(35)16(37)22(50-10)33-6-31-12-18(25)27-4-29-20(12)33/h3-6,9-10,13-16,21-22,34-37H,1-2,7-8H2,23H3,(H,38,39)(H,40,41)(H,42,43)(H,44,45)(H2,24,26,28)(H2,25,27,29)/q-1/p-4/t9-,10-,13-,14-,15-,16-,21-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...				J Med Chem 53: 8485-97 (2010) Article DOI: 10.1021/jm100597c BindingDB Entry DOI: 10.7270/Q22V2GF7
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) Show SMILES Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O Show InChI InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50366480 (ADENOSINE TRIPHOSPHATE | ATP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM18137 (AMP | CHEMBL752 | [(2R,3S,4R,5R)-5-adenin-9-yl-3,4...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Measure of Agonist Potency at human P2Y purinoceptor 11 (hP2Y11) stably expressed in 131N1 astrocytoma cell at 10 uM				J Med Chem 45: 208-18 (2001) Article DOI: 10.1021/jm010369e BindingDB Entry DOI: 10.7270/Q2JS9R58
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50409486 (CHEMBL2111533) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1[C@H]2C[C@@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C12H18N5O12P3/c13-10-6-11(15-3-14-10)17(4-16-6)7-5-1-12(5,9(19)8(7)18)2-27-31(23,24)29-32(25,26)28-30(20,21)22/h3-5,7-9,18-19H,1-2H2,(H,23,24)(H,25,26)(H2,13,14,15)(H2,20,21,22)/t5-,7-,8+,9+,12+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Measure of Agonist Potency at human P2Y purinoceptor 11 (hP2Y11) stably expressed in 131N1 astrocytoma cell at 10 uM				J Med Chem 45: 208-18 (2001) Article DOI: 10.1021/jm010369e BindingDB Entry DOI: 10.7270/Q2JS9R58
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50366480 (ADENOSINE TRIPHOSPHATE | ATP) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Agonist activity by measuring inositol phosphate accumulation in 1321N1 human astrocytoma cells stably expressing human P2Y purinoceptor 11				J Med Chem 45: 2090-100 (2002) Article DOI: 10.1021/jm010538v BindingDB Entry DOI: 10.7270/Q25H7GZB
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118230 (5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118230 (5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H15N5O9P2S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at GFP-tagged human P2Y11R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-bas...				J Med Chem 58: 8427-43 (2015) Article DOI: 10.1021/acs.jmedchem.5b00575 BindingDB Entry DOI: 10.7270/Q2736SRG
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118232 (2-MeSATP | ATP, 2-meS | CHEMBL336208) Show SMILES CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 Show InChI InChI=1S/C11H18N5O13P3S/c1-33-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50118213 (5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50029031 (1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...) Show SMILES Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O Show InChI InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50026893 (CHEMBL3085531) Show SMILES CNc1nc(Cl)nc2n(cnc12)[C@H]1C[C@@H](OP(O)(O)=O)[C@]2(COP(O)(O)=O)C[C@H]12 Show InChI InChI=1S/C13H18ClN5O8P2/c1-15-10-9-11(18-12(14)17-10)19(5-16-9)7-2-8(27-29(23,24)25)13(3-6(7)13)4-26-28(20,21)22/h5-8H,2-4H2,1H3,(H,15,17,18)(H2,20,21,22)(H2,23,24,25)/t6-,7+,8-,13+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Agonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)				J Med Chem 45: 4057-93 (2002) Article DOI: 10.1021/jm020046y BindingDB Entry DOI: 10.7270/Q2VX0H71
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50429538 (CHEMBL2333767) Show SMILES Cc1ccc(NC(=O)Nc2cccnc2Sc2ccccc2C(C)(C)C)cc1 Show InChI InChI=1S/C23H25N3OS/c1-16-11-13-17(14-12-16)25-22(27)26-19-9-7-15-24-21(19)28-20-10-6-5-8-18(20)23(2,3)4/h5-15H,1-4H3,(H2,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human P2Y11 receptor				J Med Chem 56: 1704-14 (2013) Article DOI: 10.1021/jm301708u BindingDB Entry DOI: 10.7270/Q2ST7R6G
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50429537 (CHEMBL2333770) Show SMILES CC(C)(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H22F3N3O3/c1-22(2,3)17-7-4-5-9-19(17)31-20-18(8-6-14-27-20)29-21(30)28-15-10-12-16(13-11-15)32-23(24,25)26/h4-14H,1-3H3,(H2,28,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human P2Y11 receptor				J Med Chem 56: 1704-14 (2013) Article DOI: 10.1021/jm301708u BindingDB Entry DOI: 10.7270/Q2ST7R6G
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50429536 (CHEMBL2333771) Show SMILES CC(C)(C)c1ccc(NC(=O)Nc2cccnc2Oc2ccccc2C(C)(C)C)cc1 Show InChI InChI=1S/C26H31N3O2/c1-25(2,3)18-13-15-19(16-14-18)28-24(30)29-21-11-9-17-27-23(21)31-22-12-8-7-10-20(22)26(4,5)6/h7-17H,1-6H3,(H2,28,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human P2Y11 receptor				J Med Chem 56: 1704-14 (2013) Article DOI: 10.1021/jm301708u BindingDB Entry DOI: 10.7270/Q2ST7R6G
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50429535 (CHEMBL2333772) Show SMILES CC(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C25H29N3O2/c1-17(2)20-9-6-7-11-22(20)30-23-21(10-8-16-26-23)28-24(29)27-19-14-12-18(13-15-19)25(3,4)5/h6-17H,1-5H3,(H2,27,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human P2Y11 receptor				J Med Chem 56: 1704-14 (2013) Article DOI: 10.1021/jm301708u BindingDB Entry DOI: 10.7270/Q2ST7R6G
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50429534 (CHEMBL2333773) Show SMILES CC(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C22H20F3N3O3/c1-14(2)17-6-3-4-8-19(17)30-20-18(7-5-13-26-20)28-21(29)27-15-9-11-16(12-10-15)31-22(23,24)25/h3-14H,1-2H3,(H2,27,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human P2Y11 receptor				J Med Chem 56: 1704-14 (2013) Article DOI: 10.1021/jm301708u BindingDB Entry DOI: 10.7270/Q2ST7R6G
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50456168 (CHEMBL1800685) Show SMILES OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C29H24F3NO2/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20/h1-10,15-17,20,33H,11-14H2,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Antagonist activity human P2Y11R expressed in human 1321N1 cells assessed as inhibition of ATP-induced [3H]inositol phosphate accumulation after 30 m...				J Med Chem 59: 6149-68 (2016) Article DOI: 10.1021/acs.jmedchem.6b00044
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50456168 (CHEMBL1800685) Show SMILES OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C29H24F3NO2/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20/h1-10,15-17,20,33H,11-14H2,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Antagonist activity human P2Y11R expressed in human 1321N1 cells assessed as inhibition of ATP-induced [3H]inositol phosphate accumulation after 30 m...				J Med Chem 59: 6149-68 (2016) Article DOI: 10.1021/acs.jmedchem.6b00044
					More data for this Ligand-Target Pair
Purinergic receptor P2Y11 (Homo sapiens (Human))	BDBM50422739 (CHEMBL413145) Show SMILES [O-]S(=O)(=O)c1cc(c2c(NC(=O)c3ccc(F)c(NC(=O)c4cccc(NC(=O)Nc5cccc(c5)C(=O)Nc5cc(ccc5F)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c4)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O Show InChI InChI=1S/C49H34F2N6O23S6/c50-33-9-7-25(47(60)54-35-11-13-39(83(69,70)71)31-19-29(81(63,64)65)21-41(43(31)35)85(75,76)77)17-37(33)56-45(58)23-3-1-5-27(15-23)52-49(62)53-28-6-2-4-24(16-28)46(59)57-38-18-26(8-10-34(38)51)48(61)55-36-12-14-40(84(72,73)74)32-20-30(82(66,67)68)22-42(44(32)36)86(78,79)80/h1-22H,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/p-6	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibitory concentration against P2Y11 receptor expressed in 1321N1 astrocytoma Cells; (n=7)				J Med Chem 48: 7040-8 (2005) Article DOI: 10.1021/jm050301p BindingDB Entry DOI: 10.7270/Q2JM2BZ7
					More data for this Ligand-Target Pair