Compile Data Set for Download or QSAR

Found 515 hits Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor beta'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid receptor (Homo sapiens (Human))	BDBM50032218 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1ccc(o1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O3/c1-14(11-16-7-8-20(26-16)21(24)25)17-13-19-18(12-15(17)2)22(3,4)9-10-23(19,5)6/h7-8,11-13H,9-10H2,1-6H3,(H,24,25)/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032224 (3-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cccc(c1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H30O2/c1-16(12-18-8-7-9-19(14-18)23(26)27)20-15-22-21(13-17(20)2)24(3,4)10-11-25(22,5)6/h7-9,12-15H,10-11H2,1-6H3,(H,26,27)/b16-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50265920 (4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H24O2/c1-22(2)13-14-23(3,4)20-15-17(9-12-19(20)22)6-5-16-7-10-18(11-8-16)21(24)25/h7-12,15H,13-14H2,1-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...				Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM323587 (4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2...) Show SMILES CC(=Cc1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid PDB UniChem	PDB Article US Patent	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
ACUCELA INC. US Patent					Assay Description Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...				US Patent US10188615 (2019) Article DOI: 10.1016/j.bmcl.2005.03.055 BindingDB Entry DOI: 10.7270/Q2NP26HC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50282691 (4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES Cc1cc2c(cc1\C=C\c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)11-8-17-6-9-18(10-7-17)22(25)26/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b11-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50282692 (4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...) Show SMILES CC1(C)CCC(C)(C)c2cc(\C=C\c3ccc(cc3)C(O)=O)ccc12 Show InChI InChI=1S/C23H26O2/c1-22(2)13-14-23(3,4)20-15-17(9-12-19(20)22)6-5-16-7-10-18(11-8-16)21(24)25/h5-12,15H,13-14H2,1-4H3,(H,24,25)/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50045276 (4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...) Show SMILES C\C(=C/c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50265951 (CHEMBL1657 | TAZAROTENE | US9963439, Tazarotene | ...) Show SMILES CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1 Show InChI InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...				Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta				J Med Chem 38: 4764-7 (1996) Article DOI: 10.1021/jm00024a003 BindingDB Entry DOI: 10.7270/Q22N5194
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor beta using transactivation...				Bioorg Med Chem Lett 6: 213-218 (1996) Article DOI: 10.1016/0960-894X(95)00588-K BindingDB Entry DOI: 10.7270/Q2BC3ZHZ
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 42: 4961-9 (2000) Article DOI: 10.1021/jm991059n BindingDB Entry DOI: 10.7270/Q24F1PX3
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50097824 (4-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cc2)C(O)=O)C(C)(C)CCC1 Show InChI InChI=1S/C20H22O2/c1-15-7-6-14-20(2,3)18(15)9-5-4-8-16-10-12-17(13-11-16)19(21)22/h5,9-13H,6-7,14H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Mus musculus)	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR beta				J Med Chem 41: 1679-87 (1998) Article DOI: 10.1021/jm970635h BindingDB Entry DOI: 10.7270/Q20864F4
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50052033 ((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...) Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C23H32O2/c1-16(12-21(24)25)10-9-11-17(2)18-13-19(22(3,4)5)15-20(14-18)23(6,7)8/h9-15H,1-8H3,(H,24,25)/b10-9+,16-12+,17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50052033 ((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...) Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C23H32O2/c1-16(12-21(24)25)10-9-11-17(2)18-13-19(22(3,4)5)15-20(14-18)23(6,7)8/h9-15H,1-8H3,(H,24,25)/b10-9+,16-12+,17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RAR beta in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Binding affinity against retinoic Acid beta receptors cotransfected into CV-1 cells				J Med Chem 37: 408-14 (1994) Article DOI: 10.1021/jm00029a013 BindingDB Entry DOI: 10.7270/Q20V8BT5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50290184 (4-(1-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-qui...) Show SMILES CC(C)N1CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H25NO2/c1-16(2)24-14-13-23(3,4)20-12-9-18(15-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-12,15-16H,13-14H2,1-4H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was determined for Retinoic acid receptor alpha				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31892 (9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR beta				J Med Chem 44: 2298-303 (2001) Article DOI: 10.1021/jm0100584 BindingDB Entry DOI: 10.7270/Q2P84B41
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transactivation potency of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50064254 ((2E,4E,6E,8Z)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...) Show SMILES C\C(\C=C/C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11-,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31892 (9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM31892 (9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
Università di Ferrara Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 42: 4961-9 (2000) Article DOI: 10.1021/jm991059n BindingDB Entry DOI: 10.7270/Q24F1PX3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM31892 (9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50290179 (4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahyd...) Show SMILES CC(C)N1C(=O)CC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H23NO3/c1-15(2)24-20-12-9-17(13-19(20)23(3,4)14-21(24)25)6-5-16-7-10-18(11-8-16)22(26)27/h7-13,15H,14H2,1-4H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation for RAR beta receptor				Bioorg Med Chem Lett 4: 1447-1452 (1994) Article DOI: 10.1016/S0960-894X(01)80511-4 BindingDB Entry DOI: 10.7270/Q2B8582K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) Article DOI: 10.1021/jm00015a004 BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50290178 (4-(1-Isopropyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahyd...) Show SMILES CC(C)N1C(=O)CC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H23NO3/c1-15(2)24-20-13-17(9-12-19(20)23(3,4)14-21(24)25)6-5-16-7-10-18(11-8-16)22(26)27/h7-13,15H,14H2,1-4H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transactivation potency of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50045267 (4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Effective concentration against Retinoic acid receptor beta				J Med Chem 36: 2605-13 (1993) Article DOI: 10.1021/jm00070a003 BindingDB Entry DOI: 10.7270/Q21R6PKP
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50286563 (6-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cn2)C(O)=O)C(C)(C)CCC1 Show InChI InChI=1S/C19H21NO2/c1-14-7-6-12-19(2,3)17(14)9-5-4-8-16-11-10-15(13-20-16)18(21)22/h5,9-11,13H,6-7,12H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	n/a	n/a	>5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation of retinoic acid receptor RAR beta				Bioorg Med Chem Lett 5: 523-527 (1995) Article DOI: 10.1016/0960-894X(95)00065-2 BindingDB Entry DOI: 10.7270/Q20G3K4D
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032219 ((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Effective concentration against Retinoic acid receptor beta				J Med Chem 36: 2605-13 (1993) Article DOI: 10.1021/jm00070a003 BindingDB Entry DOI: 10.7270/Q21R6PKP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay				J Med Chem 52: 1540-5 (2009) Article DOI: 10.1021/jm801532e BindingDB Entry DOI: 10.7270/Q2K938R9
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50097824 (4-[(E)-4-(2,6,6-Trimethyl-cyclohex-1-enyl)-but-3-e...) Show SMILES CC1=C(\C=C\C#Cc2ccc(cc2)C(O)=O)C(C)(C)CCC1 Show InChI InChI=1S/C20H22O2/c1-15-7-6-14-20(2,3)18(15)9-5-4-8-16-10-12-17(13-11-16)19(21)22/h5,9-13H,6-7,14H2,1-3H3,(H,21,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Binding affinity towards retinoic acid receptor alpha was determined using [3H]-ATRA (5 nM) as radioligand				Bioorg Med Chem Lett 11: 765-8 (2001) Article DOI: 10.1016/s0960-894x(01)00058-0 BindingDB Entry DOI: 10.7270/Q2348JN3
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50413272 (AC-261066 | CHEMBL198997) Show SMILES CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1 Show InChI InChI=1S/C17H20FNO4S/c1-3-4-7-22-8-9-23-15-11(2)24-16(19-15)12-5-6-13(17(20)21)14(18)10-12/h5-6,10H,3-4,7-9H2,1-2H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.94	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay				J Med Chem 52: 1540-5 (2009) Article DOI: 10.1021/jm801532e BindingDB Entry DOI: 10.7270/Q2K938R9
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50097819 (4-[(E)-3-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...) Show SMILES CC1(C)CCC(C)(C)c2cc(C\C=C\c3ccc(cc3)C(O)=O)ccc12 Show InChI InChI=1S/C24H28O2/c1-23(2)14-15-24(3,4)21-16-18(10-13-20(21)23)7-5-6-17-8-11-19(12-9-17)22(25)26/h5-6,8-13,16H,7,14-15H2,1-4H3,(H,25,26)/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor beta				Bioorg Med Chem Lett 11: 765-8 (2001) Article DOI: 10.1016/s0960-894x(01)00058-0 BindingDB Entry DOI: 10.7270/Q2348JN3
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50052588 ((2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,...) Show SMILES COc1cc2c(cc1\C(C)=C/C=C/C(/C)=C/C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H32O3/c1-16(13-22(25)26)9-8-10-17(2)18-14-19-20(15-21(18)27-7)24(5,6)12-11-23(19,3)4/h8-10,13-15H,11-12H2,1-7H3,(H,25,26)/b9-8+,16-13+,17-10-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 39: 3229-34 (1996) Article DOI: 10.1021/jm960311d BindingDB Entry DOI: 10.7270/Q2ZW1K14
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50052414 (4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...				Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50052414 (4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Binding affinity for retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 12: 3145-8 (2002) Article DOI: 10.1016/s0960-894x(02)00647-9 BindingDB Entry DOI: 10.7270/Q2WW7H0H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50052589 ((2E,4E,6Z)-3-Methyl-7-(5,5,8,8-tetramethyl-3-propo...) Show SMILES CCCOc1cc2c(cc1\C(C)=C/C=C/C(/C)=C/C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C26H36O3/c1-8-14-29-23-17-22-21(25(4,5)12-13-26(22,6)7)16-20(23)19(3)11-9-10-18(2)15-24(27)28/h9-11,15-17H,8,12-14H2,1-7H3,(H,27,28)/b10-9+,18-15+,19-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 39: 3229-34 (1996) Article DOI: 10.1021/jm960311d BindingDB Entry DOI: 10.7270/Q2ZW1K14
					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoid receptor (Homo sapiens (Human))	BDBM50290185 (4-(1-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-qui...) Show SMILES CC(C)N1CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H25NO2/c1-16(2)24-14-13-23(3,4)20-15-18(9-12-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-12,15-16H,13-14H2,1-4H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transactivation potency of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50265917 (4-((4-tert-butylphenyl)ethynyl)benzoic acid | CHEM...) Show SMILES CC(C)(C)c1ccc(cc1)C#Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C19H18O2/c1-19(2,3)17-12-8-15(9-13-17)5-4-14-6-10-16(11-7-14)18(20)21/h6-13H,1-3H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...				Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h...				Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...) Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Effective concentration against Retinoic acid receptor beta				J Med Chem 36: 2605-13 (1993) Article DOI: 10.1021/jm00070a003 BindingDB Entry DOI: 10.7270/Q21R6PKP
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50045266 (4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1 Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Effective concentration against Retinoic acid receptor beta				J Med Chem 36: 2605-13 (1993) Article DOI: 10.1021/jm00070a003 BindingDB Entry DOI: 10.7270/Q21R6PKP
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50413260 (CHEMBL198794) Show SMILES CCCCCCCCCc1ccc(cc1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H28O2/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)20-14-16-21(17-15-20)22(23)24/h10-17H,2-9H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15.8	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay				J Med Chem 52: 1540-5 (2009) Article DOI: 10.1021/jm801532e BindingDB Entry DOI: 10.7270/Q2K938R9
					More data for this Ligand-Target Pair

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