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Compile Data Set for Download or QSAR

Found 372 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase D1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324346
PNG
(CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...)
Show SMILES C1CCC(CC1)Nc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)-c1cn[nH]c1
Show InChI InChI=1S/C23H29N7/c1-2-4-20(5-3-1)28-22-13-17(6-7-25-22)21-12-18(19-15-26-27-16-19)14-23(29-21)30-10-8-24-9-11-30/h6-7,12-16,20,24H,1-5,8-11H2,(H,25,28)(H,26,27)
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n/an/an/an/a 17n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324324
PNG
(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Show SMILES NC(=O)c1cc(nc(c1)-c1ccnc(Nc2ccccc2)c1)N1CCNCC1
Show InChI InChI=1S/C21H22N6O/c22-21(28)16-12-18(26-20(14-16)27-10-8-23-9-11-27)15-6-7-24-19(13-15)25-17-4-2-1-3-5-17/h1-7,12-14,23H,8-11H2,(H2,22,28)(H,24,25)
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n/an/an/an/a 24n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324331
PNG
(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Show SMILES N#Cc1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C21H26N6/c22-15-16-12-19(26-21(13-16)27-10-8-23-9-11-27)17-6-7-24-20(14-17)25-18-4-2-1-3-5-18/h6-7,12-14,18,23H,1-5,8-11H2,(H,24,25)
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n/an/an/an/a 66n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324323
PNG
(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Show SMILES NC(=O)c1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C21H28N6O/c22-21(28)16-12-18(26-20(14-16)27-10-8-23-9-11-27)15-6-7-24-19(13-15)25-17-4-2-1-3-5-17/h6-7,12-14,17,23H,1-5,8-11H2,(H2,22,28)(H,24,25)
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n/an/an/an/a 77n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324347
PNG
(CHEMBL1215153 | Isopropyl-[6-piperazin-1-yl-4-(1H-...)
Show SMILES CC(C)Nc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)-c1cn[nH]c1
Show InChI InChI=1S/C20H25N7/c1-14(2)25-19-10-15(3-4-22-19)18-9-16(17-12-23-24-13-17)11-20(26-18)27-7-5-21-6-8-27/h3-4,9-14,21H,5-8H2,1-2H3,(H,22,25)(H,23,24)
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n/an/an/an/a 92n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324322
PNG
(4-(2-cyclohexylaminopyridin-4-yl)-6-(piperazin-1-y...)
Show SMILES O=C1NCc2c1cc(nc2-c1ccnc(NC2CCCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C22H28N6O/c29-22-17-13-20(28-10-8-23-9-11-28)27-21(18(17)14-25-22)15-6-7-24-19(12-15)26-16-4-2-1-3-5-16/h6-7,12-13,16,23H,1-5,8-11,14H2,(H,24,26)(H,25,29)
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n/an/an/an/a 115n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324329
PNG
(2'-Cyclopentylamino-6-piperazin-1-yl[2,4']bipyridi...)
Show SMILES NC(=O)c1cc(nc(c1)-c1ccnc(NC2CCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C20H26N6O/c21-20(27)15-11-17(25-19(13-15)26-9-7-22-8-10-26)14-5-6-23-18(12-14)24-16-3-1-2-4-16/h5-6,11-13,16,22H,1-4,7-10H2,(H2,21,27)(H,23,24)
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n/an/an/an/a 202n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324348
PNG
(6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...)
Show SMILES C1CN(CCN1)c1cc(cc(n1)-c1ccnc(NC2CCOCC2)c1)-c1cn[nH]c1
Show InChI InChI=1S/C22H27N7O/c1-4-24-21(27-19-2-9-30-10-3-19)12-16(1)20-11-17(18-14-25-26-15-18)13-22(28-20)29-7-5-23-6-8-29/h1,4,11-15,19,23H,2-3,5-10H2,(H,24,27)(H,25,26)
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n/an/an/an/a 234n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324344
PNG
(CHEMBL1215360 | Cyclohexyl-(6-piperazin-1-yl-4-tri...)
Show SMILES FC(F)(F)c1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C21H26F3N5/c22-21(23,24)16-13-18(28-20(14-16)29-10-8-25-9-11-29)15-6-7-26-19(12-15)27-17-4-2-1-3-5-17/h6-7,12-14,17,25H,1-5,8-11H2,(H,26,27)
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n/an/an/an/a 342n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324332
PNG
(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Show SMILES N#Cc1cc(nc(c1)-c1ccnc(Nc2ccccc2)c1)N1CCNCC1
Show InChI InChI=1S/C21H20N6/c22-15-16-12-19(26-21(13-16)27-10-8-23-9-11-27)17-6-7-24-20(14-17)25-18-4-2-1-3-5-18/h1-7,12-14,23H,8-11H2,(H,24,25)
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n/an/an/an/a 378n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324333
PNG
(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Show SMILES Cn1ccc(Nc2cc(ccn2)-c2cc(cc(n2)N2CCNCC2)C#N)n1
Show InChI InChI=1S/C19H20N8/c1-26-7-3-17(25-26)24-18-12-15(2-4-22-18)16-10-14(13-20)11-19(23-16)27-8-5-21-6-9-27/h2-4,7,10-12,21H,5-6,8-9H2,1H3,(H,22,24,25)
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n/an/an/an/a 428n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324326
PNG
(4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...)
Show SMILES CC(C)Nc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)C(N)=O
Show InChI InChI=1S/C18H24N6O/c1-12(2)22-16-10-13(3-4-21-16)15-9-14(18(19)25)11-17(23-15)24-7-5-20-6-8-24/h3-4,9-12,20H,5-8H2,1-2H3,(H2,19,25)(H,21,22)
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n/an/an/an/a 438n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324328
PNG
(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Show SMILES NC(=O)c1cc(nc(c1)-c1ccnc(Nc2ccccc2Cl)c1)N1CCNCC1
Show InChI InChI=1S/C21H21ClN6O/c22-16-3-1-2-4-17(16)26-19-12-14(5-6-25-19)18-11-15(21(23)29)13-20(27-18)28-9-7-24-8-10-28/h1-6,11-13,24H,7-10H2,(H2,23,29)(H,25,26)
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n/an/an/an/a 478n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324345
PNG
(CHEMBL1215361 | Cyclohexyl-(4-difluoromethyl-6-pip...)
Show SMILES FC(F)c1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1
Show InChI InChI=1S/C21H27F2N5/c22-21(23)16-12-18(27-20(14-16)28-10-8-24-9-11-28)15-6-7-25-19(13-15)26-17-4-2-1-3-5-17/h6-7,12-14,17,21,24H,1-5,8-11H2,(H,25,26)
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n/an/an/an/a 568n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324327
PNG
(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Show SMILES Cn1ccc(Nc2cc(ccn2)-c2cc(cc(n2)N2CCNCC2)C(N)=O)n1
Show InChI InChI=1S/C19H22N8O/c1-26-7-3-16(25-26)24-17-11-13(2-4-22-17)15-10-14(19(20)28)12-18(23-15)27-8-5-21-6-9-27/h2-4,7,10-12,21H,5-6,8-9H2,1H3,(H2,20,28)(H,22,24,25)
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n/an/an/an/a 674n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324337
PNG
(2'-Cyclohexylamino-6-((R)-3-methylpiperazin-1-yl)[...)
Show SMILES C[C@@H]1CN(CCN1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C22H30N6O/c1-15-14-28(10-9-24-15)21-13-17(22(23)29)11-19(27-21)16-7-8-25-20(12-16)26-18-5-3-2-4-6-18/h7-8,11-13,15,18,24H,2-6,9-10,14H2,1H3,(H2,23,29)(H,25,26)/t15-/m1/s1
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n/an/an/an/a 679n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324334
PNG
(CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...)
Show SMILES C1CCC(CC1)Nc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)-c1cc[nH]n1
Show InChI InChI=1S/C23H29N7/c1-2-4-19(5-3-1)27-22-15-17(6-8-25-22)21-14-18(20-7-9-26-29-20)16-23(28-21)30-12-10-24-11-13-30/h6-9,14-16,19,24H,1-5,10-13H2,(H,25,27)(H,26,29)
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n/an/an/an/a 704n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324340
PNG
(2'-Cyclohexylamino-6-(4-methylpiperazin-1-yl)[2,4'...)
Show SMILES CN1CCN(CC1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C22H30N6O/c1-27-9-11-28(12-10-27)21-15-17(22(23)29)13-19(26-21)16-7-8-24-20(14-16)25-18-5-3-2-4-6-18/h7-8,13-15,18H,2-6,9-12H2,1H3,(H2,23,29)(H,24,25)
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n/an/an/an/a 752n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324338
PNG
(2'-Cyclohexylamino-6-((S)-3-methylpiperazin-1-yl)[...)
Show SMILES C[C@H]1CN(CCN1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C22H30N6O/c1-15-14-28(10-9-24-15)21-13-17(22(23)29)11-19(27-21)16-7-8-25-20(12-16)26-18-5-3-2-4-6-18/h7-8,11-13,15,18,24H,2-6,9-10,14H2,1H3,(H2,23,29)(H,25,26)/t15-/m0/s1
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n/an/an/an/a 831n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324339
PNG
(3-Amino-2''-cyclohexylamino-3,4,5,6-tetrahydro-2H-...)
Show SMILES NC1CCCN(C1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C22H30N6O/c23-17-5-4-10-28(14-17)21-13-16(22(24)29)11-19(27-21)15-8-9-25-20(12-15)26-18-6-2-1-3-7-18/h8-9,11-13,17-18H,1-7,10,14,23H2,(H2,24,29)(H,25,26)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324330
PNG
(2'-Ethylamino-6-piperazin-1-yl[2,4']bipyridinyl-4-...)
Show SMILES CCNc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)C(N)=O
Show InChI InChI=1S/C17H22N6O/c1-2-20-15-10-12(3-4-21-15)14-9-13(17(18)24)11-16(22-14)23-7-5-19-6-8-23/h3-4,9-11,19H,2,5-8H2,1H3,(H2,18,24)(H,20,21)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324341
PNG
(Aminomethyl-2''-cyclohexylamino-3,4,5,6-tetrahydro...)
Show SMILES NCC1CCN(CC1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C23H32N6O/c24-15-16-7-10-29(11-8-16)22-14-18(23(25)30)12-20(28-22)17-6-9-26-21(13-17)27-19-4-2-1-3-5-19/h6,9,12-14,16,19H,1-5,7-8,10-11,15,24H2,(H2,25,30)(H,26,27)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324325
PNG
(6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...)
Show SMILES NC(=O)c1cc(nc(c1)-c1ccnc(NC2CCOCC2)c1)N1CCNCC1
Show InChI InChI=1S/C20H26N6O2/c21-20(27)15-11-17(25-19(13-15)26-7-5-22-6-8-26)14-1-4-23-18(12-14)24-16-2-9-28-10-3-16/h1,4,11-13,16,22H,2-3,5-10H2,(H2,21,27)(H,23,24)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324321
PNG
(6-(2-Cyclohexylaminopyridin-4-yl)-4-piperazin-1-yl...)
Show SMILES O=C1NCc2c1cc(nc2N1CCNCC1)-c1ccnc(NC2CCCCC2)c1
Show InChI InChI=1S/C22H28N6O/c29-22-17-13-19(27-21(18(17)14-25-22)28-10-8-23-9-11-28)15-6-7-24-20(12-15)26-16-4-2-1-3-5-16/h6-7,12-13,16,23H,1-5,8-11,14H2,(H,24,26)(H,25,29)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324336
PNG
(2'-Cyclohexylamino-6-((S)-pyrrolidin-3-ylamino)[2,...)
Show SMILES NC(=O)c1cc(N[C@H]2CCNC2)nc(c1)-c1ccnc(NC2CCCCC2)c1
Show InChI InChI=1S/C21H28N6O/c22-21(28)15-10-18(27-20(12-15)26-17-7-8-23-13-17)14-6-9-24-19(11-14)25-16-4-2-1-3-5-16/h6,9-12,16-17,23H,1-5,7-8,13H2,(H2,22,28)(H,24,25)(H,26,27)/t17-/m0/s1
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324342
PNG
(2'-Cyclohexylamino-6-(3,3-dimethylpiperazin-1-yl)[...)
Show SMILES CC1(C)CN(CCN1)c1cc(cc(n1)-c1ccnc(NC2CCCCC2)c1)C(N)=O
Show InChI InChI=1S/C23H32N6O/c1-23(2)15-29(11-10-26-23)21-14-17(22(24)30)12-19(28-21)16-8-9-25-20(13-16)27-18-6-4-3-5-7-18/h8-9,12-14,18,26H,3-7,10-11,15H2,1-2H3,(H2,24,30)(H,25,27)
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50324335
PNG
(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Show SMILES NC(=O)c1cc(N[C@@H]2CCNC2)nc(c1)-c1ccnc(NC2CCCCC2)c1
Show InChI InChI=1S/C21H28N6O/c22-21(28)15-10-18(27-20(12-15)26-17-7-8-23-13-17)14-6-9-24-19(11-14)25-16-4-2-1-3-5-16/h6,9-12,16-17,23H,1-5,7-8,13H2,(H2,22,28)(H,24,25)(H,26,27)/t17-/m1/s1
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n/an/an/an/a>1.00E+3n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export


J Med Chem 53: 5422-38 (2010)


Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM50427363
PNG
(CHEMBL2326002)
Show SMILES CC(C)[C@@](C)(O)[C@@H]1CN(CCN1)c1nc(-c2n[nH]c3ncccc23)c(F)cc1Cl
Show InChI InChI=1S/C20H24ClFN6O/c1-11(2)20(3,29)15-10-28(8-7-23-15)19-13(21)9-14(22)17(25-19)16-12-5-4-6-24-18(12)27-26-16/h4-6,9,11,15,23,29H,7-8,10H2,1-3H3,(H,24,26,27)/t15-,20+/m0/s1
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2.42E+3n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals (Europe) Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PKC mu (unknown origin)


J Med Chem 56: 1799-810 (2013)


Article DOI: 10.1021/jm301465a
BindingDB Entry DOI: 10.7270/Q2M046R2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM16173
PNG
(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
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n/an/a 6.88E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32333
PNG
((6Z)-6-[4-(3-aminopropylamino)-6-methyl-1H-pyrimid...)
Show SMILES Cc1cc(NCCCN)nc(n1)-c1ccccc1O
Show InChI InChI=1S/C14H18N4O/c1-10-9-13(16-8-4-7-15)18-14(17-10)11-5-2-3-6-12(11)19/h2-3,5-6,9,19H,4,7-8,15H2,1H3,(H,16,17,18)
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n/an/a 4.40E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32334
PNG
(7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c...)
Show SMILES Oc1ccc2oc3c(CCCNC3=O)c2c1
Show InChI InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)
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n/an/a 742n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32335
PNG
(MLS000087884 | N-[2-(2-methylphenyl)-2,6-dihydro-4...)
Show SMILES CCC(=O)Nc1c2CSCc2nn1-c1ccccc1C
Show InChI InChI=1S/C15H17N3OS/c1-3-14(19)16-15-11-8-20-9-12(11)17-18(15)13-7-5-4-6-10(13)2/h4-7H,3,8-9H2,1-2H3,(H,16,19)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32336
PNG
((5-acetyloxy-4-methyl-2-oxidanylidene-chromen-7-yl...)
Show SMILES CC(=O)Oc1cc(OC(C)=O)c2c(C)cc(=O)oc2c1
Show InChI InChI=1S/C14H12O6/c1-7-4-13(17)20-12-6-10(18-8(2)15)5-11(14(7)12)19-9(3)16/h4-6H,1-3H3
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32337
PNG
(MLS000028832 | SMR000058536 | STAUROSPORINE | cid_...)
Show SMILES CN[C@H]1C[C@H]2O[C@@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20+,26-,28-/m0/s1
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n/an/a<100n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32338
PNG
(4-amino-7-(3,4-dihydroxy-5-methylol-tetrahydrofura...)
Show SMILES NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12
Show InChI InChI=1S/C12H15N5O5/c13-9-6-4(10(14)21)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)22-12/h1,3,5,7-8,12,18-20H,2H2,(H2,14,21)(H2,13,15,16)
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n/an/a 1.66E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32339
PNG
(5-Bromo-furan-2-carboxylic acid [2-(4-methanesulfo...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccccc1NC(=O)c1ccc(Br)o1
Show InChI InChI=1S/C16H18BrN3O4S/c1-25(22,23)20-10-8-19(9-11-20)13-5-3-2-4-12(13)18-16(21)14-6-7-15(17)24-14/h2-7H,8-11H2,1H3,(H,18,21)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32340
PNG
(3-ethyl-6-methoxy-1H-benzo[de]cinnoline | MLS00053...)
Show SMILES CCc1n[nH]c2cccc3c(OC)ccc1c23
Show InChI InChI=1S/C14H14N2O/c1-3-11-9-7-8-13(17-2)10-5-4-6-12(14(9)10)16-15-11/h4-8,16H,3H2,1-2H3
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n/an/a 2.18E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32341
PNG
(5-(3-Chloro-phenyl)-furan-2-carboxylic acid (4-mor...)
Show SMILES Clc1cccc(c1)-c1ccc(o1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)
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n/an/a 8.02E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32342
PNG
((2-amino-6-nitro-1,3-benzothiazol-7-yl)amine | 2,7...)
Show SMILES Nc1nc2ccc(c(N)c2s1)[N+]([O-])=O
Show InChI InChI=1S/C7H6N4O2S/c8-5-4(11(12)13)2-1-3-6(5)14-7(9)10-3/h1-2H,8H2,(H2,9,10)
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n/an/a 9.62E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32343
PNG
((3,5-dichloro-4-pyridyl)-(4-pyridylmethyleneamino)...)
Show SMILES Clc1cncc(Cl)c1N=NCc1ccncc1
Show InChI InChI=1S/C11H8Cl2N4/c12-9-6-15-7-10(13)11(9)17-16-5-8-1-3-14-4-2-8/h1-4,6-7H,5H2
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n/an/a 1.20E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32344
PNG
(MLS000723809 | N-(4-nitrophenyl)-9-acridinamine | ...)
Show SMILES [O-][N+](=O)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1
Show InChI InChI=1S/C19H13N3O2/c23-22(24)14-11-9-13(10-12-14)20-19-15-5-1-3-7-17(15)21-18-8-4-2-6-16(18)19/h1-12H,(H,20,21)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32345
PNG
(MLS000391610 | N'-(2-benzo[cd]indolyl)-4-bromobenz...)
Show SMILES Brc1ccc(cc1)C(=O)NNC1=Nc2cccc3cccc1c23
Show InChI InChI=1S/C18H12BrN3O/c19-13-9-7-12(8-10-13)18(23)22-21-17-14-5-1-3-11-4-2-6-15(20-17)16(11)14/h1-10H,(H,20,21)(H,22,23)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32346
PNG
(2-[(3-methoxycarbonyl-5,6,7,8-tetrahydro-4H-cycloh...)
Show SMILES COC(=O)c1c(NC(=O)C2C3CCC(C3)C2C(O)=O)sc2CCCCCc12
Show InChI InChI=1S/C20H25NO5S/c1-26-20(25)16-12-5-3-2-4-6-13(12)27-18(16)21-17(22)14-10-7-8-11(9-10)15(14)19(23)24/h10-11,14-15H,2-9H2,1H3,(H,21,22)(H,23,24)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32347
PNG
(MLS000674332 | N-(4-fluorobenzyl)-2-(methylthio)be...)
Show SMILES CSc1ccccc1C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C15H14FNOS/c1-19-14-5-3-2-4-13(14)15(18)17-10-11-6-8-12(16)9-7-11/h2-9H,10H2,1H3,(H,17,18)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32348
PNG
(6-(2-methyl-2,3-dihydro-1H-indol-1-yl)-5-nitro-4-p...)
Show SMILES CC1Cc2ccccc2N1c1ncnc(N)c1[N+]([O-])=O
Show InChI InChI=1S/C13H13N5O2/c1-8-6-9-4-2-3-5-10(9)17(8)13-11(18(19)20)12(14)15-7-16-13/h2-5,7-8H,6H2,1H3,(H2,14,15,16)
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n/an/a 3.69E+3n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32349
PNG
(MLS000688854 | N'-(2-furanylmethyl)-N-(5-methyl-3-...)
Show SMILES Cc1cc(NC(=O)CCC(=O)N(Cc2ccco2)C(C(=O)NCC2CCCO2)c2ccncc2)no1
Show InChI InChI=1S/C25H29N5O6/c1-17-14-21(29-36-17)28-22(31)6-7-23(32)30(16-20-5-3-13-35-20)24(18-8-10-26-11-9-18)25(33)27-15-19-4-2-12-34-19/h3,5,8-11,13-14,19,24H,2,4,6-7,12,15-16H2,1H3,(H,27,33)(H,28,29,31)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32350
PNG
(MLS000708313 | N-(2-pyrrolidin-1-ylcarbonylphenyl)...)
Show SMILES O=C(Nc1ccccc1C(=O)N1CCCC1)C1COc2ccccc2O1
Show InChI InChI=1S/C20H20N2O4/c23-19(18-13-25-16-9-3-4-10-17(16)26-18)21-15-8-2-1-7-14(15)20(24)22-11-5-6-12-22/h1-4,7-10,18H,5-6,11-13H2,(H,21,23)
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32351
PNG
(1-phenyl-2-[(3-pyridin-3-yl-[1,2,4]triazolo[4,3-b]...)
Show SMILES O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)c1ccccc1
Show InChI InChI=1S/C18H13N5OS/c24-15(13-5-2-1-3-6-13)12-25-17-9-8-16-20-21-18(23(16)22-17)14-7-4-10-19-11-14/h1-11H,12H2
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32352
PNG
(2-(3-besylpropanoylimino)-3,4-dimethyl-4-thiazolin...)
Show SMILES CCOC(=O)c1sc(=NC(=O)CCS(=O)(=O)c2ccccc2)n(C)c1C
Show InChI InChI=1S/C17H20N2O5S2/c1-4-24-16(21)15-12(2)19(3)17(25-15)18-14(20)10-11-26(22,23)13-8-6-5-7-9-13/h5-9H,4,10-11H2,1-3H3
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase D1


(Homo sapiens)
BDBM32353
PNG
(3-(2,5-dichlorophenyl)-1,3-thiazolan-4-one | 3-(2,...)
Show SMILES Clc1ccc(Cl)c(c1)N1CSCC1=O
Show InChI InChI=1S/C9H7Cl2NOS/c10-6-1-2-7(11)8(3-6)12-5-14-4-9(12)13/h1-3H,4-5H2
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n/an/a>5.00E+4n/an/an/an/a7.223



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2FJ2F43
More data for this
Ligand-Target Pair
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