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Compile Data Set for Download or QSAR

Found 1067 hits Enz. Inhib. hit(s) with Target = 'Serotonin receptor 2a and 2c (5HT2A and 5HT2C)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50014945
PNG
(3-(2-aminopropyl)-1H-indol-5-ol | CHEMBL275854 | a...)
Show SMILES CC(N)Cc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3
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n/an/an/an/a 1.80n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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n/an/an/an/a 2.80n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50014219
PNG
(2-(5-Methoxy-1H-indol-3-yl)-1-methyl-ethylamine | ...)
Show SMILES COc1ccc2[nH]cc(CC(C)N)c2c1
Show InChI InChI=1S/C12H16N2O/c1-8(13)5-9-7-14-12-4-3-10(15-2)6-11(9)12/h3-4,6-8,14H,5,13H2,1-2H3
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n/an/an/an/a 3.10n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180251
PNG
(1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...)
Show SMILES C[C@H](N)Cn1ncc2ccc(O)cc12
Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1
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n/an/an/an/a 3.70n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210083
PNG
(CHEMBL232995 | [8-((R)-2-amino-propyl)-2,3,6,7-tet...)
Show SMILES C[C@@H](N)Cc1c2CCOc2c(COCC(=O)Oc2ccccc2)c2CCOc12
Show InChI InChI=1S/C22H25NO5/c1-14(23)11-18-16-7-9-27-22(16)19(17-8-10-26-21(17)18)12-25-13-20(24)28-15-5-3-2-4-6-15/h2-6,14H,7-13,23H2,1H3/t14-/m1/s1
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n/an/an/an/a 4.5n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180257
PNG
(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Show SMILES NCCn1ncc2ccc(O)cc12
Show InChI InChI=1S/C9H11N3O/c10-3-4-12-9-5-8(13)2-1-7(9)6-11-12/h1-2,5-6,13H,3-4,10H2
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n/an/an/an/a 4.5n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180255
PNG
(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Show SMILES C[C@H](N)Cn1ncc2ccc(O)c(Cl)c12
Show InChI InChI=1S/C10H12ClN3O/c1-6(12)5-14-10-7(4-13-14)2-3-8(15)9(10)11/h2-4,6,15H,5,12H2,1H3/t6-/m0/s1
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n/an/an/an/a 4.90n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180258
PNG
(1-((S)-2-aminopropyl)-7-fluoro-1H-indazol-6-ol | C...)
Show SMILES C[C@H](N)Cn1ncc2ccc(O)c(F)c12
Show InChI InChI=1S/C10H12FN3O/c1-6(12)5-14-10-7(4-13-14)2-3-8(15)9(10)11/h2-4,6,15H,5,12H2,1H3/t6-/m0/s1
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n/an/an/an/a 5.5n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180252
PNG
((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...)
Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1
Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1
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n/an/an/an/a 6.70n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180253
PNG
(1-((S)-2-aminopropyl)-7-methyl-1H-indazol-6-ol | C...)
Show SMILES C[C@H](N)Cn1ncc2ccc(O)c(C)c12
Show InChI InChI=1S/C11H15N3O/c1-7(12)6-14-11-8(2)10(15)4-3-9(11)5-13-14/h3-5,7,15H,6,12H2,1-2H3/t7-/m0/s1
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n/an/an/an/a 7.30n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210079
PNG
((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Show SMILES COCCOCc1c2CCOc2c(C[C@@H](C)N)c2CCOc12
Show InChI InChI=1S/C17H25NO4/c1-11(18)9-14-12-3-5-22-17(12)15(10-20-8-7-19-2)13-4-6-21-16(13)14/h11H,3-10,18H2,1-2H3/t11-/m1/s1
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n/an/an/an/a 8.60n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210078
PNG
((R)-2-(8-methoxymethyl-2,3,6,7-tetrahydro-benzo[1,...)
Show SMILES COCc1c2CCOc2c(C[C@@H](C)N)c2CCOc12
Show InChI InChI=1S/C15H21NO3/c1-9(16)7-12-10-3-5-19-15(10)13(8-17-2)11-4-6-18-14(11)12/h9H,3-8,16H2,1-2H3/t9-/m1/s1
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n/an/an/an/a 12.6n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50133231
PNG
((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)
Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I
Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
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n/an/an/an/a 30n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50133231
PNG
((R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine |...)
Show SMILES COc1cc(C[C@@H](C)N)c(OC)cc1I
Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
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n/an/an/an/a 30.2n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210081
PNG
((1R,2R)-2-amino-1-(8-bromo-2,3,6,7-tetrahydro-benz...)
Show SMILES C[C@@H](N)[C@H](O)c1c2CCOc2c(Br)c2CCOc12
Show InChI InChI=1S/C13H16BrNO3/c1-6(15)11(16)9-7-2-4-18-13(7)10(14)8-3-5-17-12(8)9/h6,11,16H,2-5,15H2,1H3/t6-,11+/m1/s1
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n/an/an/an/a 39n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50309343
PNG
(8-methyl-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Show SMILES Cc1cccc2N3CCNCCC3NC(=O)c12
Show InChI InChI=1S/C13H17N3O/c1-9-3-2-4-10-12(9)13(17)15-11-5-6-14-7-8-16(10)11/h2-4,11,14H,5-8H2,1H3,(H,15,17)
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n/an/an/an/a 61n/an/an/an/a



Bristol-Myers Squibb Co

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor in rat fundus


Bioorg Med Chem Lett 20: 1128-33 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.014
BindingDB Entry DOI: 10.7270/Q2K074DK
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM30707
PNG
(2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...)
Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1
Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
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n/an/an/an/a 78n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210084
PNG
((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...)
Show SMILES C[C@@H](N)Cc1c2ccoc2c(Cc2nc(C)no2)c2ccoc12
Show InChI InChI=1S/C17H17N3O3/c1-9(18)7-13-11-3-5-22-17(11)14(12-4-6-21-16(12)13)8-15-19-10(2)20-23-15/h3-6,9H,7-8,18H2,1-2H3/t9-/m1/s1
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n/an/an/an/a 82n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50180256
PNG
(1-((R)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL4373...)
Show SMILES C[C@@H](N)Cn1ncc2ccc(O)cc12
Show InChI InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m1/s1
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n/an/an/an/a 87n/an/an/an/a



Alcon Research, Ltd.

Curated by ChEMBL


Assay Description
Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells


J Med Chem 49: 318-28 (2006)


Article DOI: 10.1021/jm050663x
BindingDB Entry DOI: 10.7270/Q23B5ZQW
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50210085
PNG
((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...)
Show SMILES C[C@@H](N)Cc1c2CCOc2c(Cc2nc(C)no2)c2CCOc12
Show InChI InChI=1S/C17H21N3O3/c1-9(18)7-13-11-3-5-22-17(11)14(12-4-6-21-16(12)13)8-15-19-10(2)20-23-15/h9H,3-8,18H2,1-2H3/t9-/m1/s1
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n/an/an/an/a 689n/an/an/an/a



Alcon Research, Ltd

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT


Bioorg Med Chem Lett 17: 2998-3002 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.073
BindingDB Entry DOI: 10.7270/Q2KS6R7B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50059890
PNG
(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Show SMILES COc1c2OCCc2c(CCN)c2CCOc12
Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3
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n/an/an/an/a 1.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor


J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50059893
PNG
(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Show SMILES CCOc1c(OC)cc(CCN)cc1OC
Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor


J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50059892
PNG
(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Show SMILES COc1cc(CCN)c2CCOc2c1OC
Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor


J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50059891
PNG
(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Show SMILES COc1cc(CCN)cc(OC)c1OC
Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
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n/an/an/an/a 2.40E+4n/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptor


J Med Chem 40: 2997-3008 (1997)


Article DOI: 10.1021/jm970219x
BindingDB Entry DOI: 10.7270/Q2RF5T50
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098525
PNG
(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12
Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m1/s1
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0.110n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM50145624
PNG
(CHEMBL3764539)
Show SMILES Clc1cccc(c1)N1CCN(CCNC(=O)c2ccncc2)CC1
Show InChI InChI=1S/C18H21ClN4O/c19-16-2-1-3-17(14-16)23-12-10-22(11-13-23)9-8-21-18(24)15-4-6-20-7-5-15/h1-7,14H,8-13H2,(H,21,24)
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0.156n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50115642
PNG
((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Show SMILES COc1cccc2Cc3ccccc3[C@H]3CN(C)CCN3c12
Show InChI InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3/t17-/m1/s1
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0.160n/an/an/an/an/an/an/an/a



University Center for Pharmacy

Curated by ChEMBL


Assay Description
The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergine


J Med Chem 45: 3280-5 (2002)


Article DOI: 10.1021/jm010566d
BindingDB Entry DOI: 10.7270/Q28051ZZ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM85097
PNG
(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl
Show InChI InChI=1S/C21H19ClN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
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0.160n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry


Bioorg Med Chem Lett 26: 914-20 (2016)


Article DOI: 10.1016/j.bmcl.2015.12.071
BindingDB Entry DOI: 10.7270/Q2VX0JC7
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50001775
PNG
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Show SMILES Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3
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0.200n/an/an/an/an/an/an/an/a



Vanderbilt University

Curated by PDSP Ki Database




J Pharmacol Exp Ther 247: 169-73 (1988)


BindingDB Entry DOI: 10.7270/Q2ZS2V0B
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50115643
PNG
((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Show SMILES COc1cccc2Cc3ccccc3C3CN(C)CCN3c12
Show InChI InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3
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0.210n/an/an/an/an/an/an/an/a



University Center for Pharmacy

Curated by ChEMBL


Assay Description
The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergine


J Med Chem 45: 3280-5 (2002)


Article DOI: 10.1021/jm010566d
BindingDB Entry DOI: 10.7270/Q28051ZZ
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098526
PNG
(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12
Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m0/s1
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0.25n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098532
PNG
(2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...)
Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12
Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m1/s1
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0.260n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50115640
PNG
((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Show SMILES COc1cccc2Cc3ccccc3[C@@H]3CN(C)CCN3c12
Show InChI InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3/t17-/m0/s1
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0.390n/an/an/an/an/an/an/an/a



University Center for Pharmacy

Curated by ChEMBL


Assay Description
The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergine


J Med Chem 45: 3280-5 (2002)


Article DOI: 10.1021/jm010566d
BindingDB Entry DOI: 10.7270/Q28051ZZ
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM35256
PNG
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)
Show SMILES CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21
Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1
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0.400n/an/an/an/an/an/an/an/a



University of Turku

Curated by PDSP Ki Database




Psychopharmacology (Berl) 126: 234-40 (1996)


BindingDB Entry DOI: 10.7270/Q2BP0192
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098530
PNG
(1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...)
Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F
Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m1/s1
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0.400n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50001786
PNG
(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12
Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)
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0.510n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine (0.5 nM) from rat 5-hydroxytryptamine 2C receptor expressed in SR-3T3 cells


J Med Chem 46: 265-83 (2003)


Article DOI: 10.1021/jm020938y
BindingDB Entry DOI: 10.7270/Q2TB17MV
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50001786
PNG
(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12
Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)
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0.510n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by PDSP Ki Database




Neuropsychopharmacology 18: 63-101 (1998)


Article DOI: 10.1016/S0893-133X(97)00112-7
BindingDB Entry DOI: 10.7270/Q2SF2TQB
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50048803
PNG
(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
Show SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12
Show InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
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0.550n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by PDSP Ki Database




Neuropsychopharmacology 18: 63-101 (1998)


Article DOI: 10.1016/S0893-133X(97)00112-7
BindingDB Entry DOI: 10.7270/Q2SF2TQB
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM50140071
PNG
(CHEMBL3752465)
Show SMILES CN(C)CCC(Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cc1)c1ccccc1
Show InChI InChI=1S/C27H30ClN3O2/c1-19-17-21-13-16-31(25(21)18-24(19)28)27(32)29-22-9-11-23(12-10-22)33-26(14-15-30(2)3)20-7-5-4-6-8-20/h4-12,17-18,26H,13-16H2,1-3H3,(H,29,32)
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0.600n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometry


Bioorg Med Chem Lett 26: 914-20 (2016)


Article DOI: 10.1016/j.bmcl.2015.12.071
BindingDB Entry DOI: 10.7270/Q2VX0JC7
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50013050
PNG
(CHEMBL3261693)
Show SMILES CN(C)CCC(Oc1ccc(NC(=O)Nc2ccc(C)c(Cl)c2)cc1)c1ccccc1
Show InChI InChI=1S/C25H28ClN3O2/c1-18-9-10-21(17-23(18)26)28-25(30)27-20-11-13-22(14-12-20)31-24(15-16-29(2)3)19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H2,27,28,30)
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0.600n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat choroid plexus membranes after 30 mins by liquid scintillation spectrophot...


Bioorg Med Chem Lett 24: 2118-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.043
BindingDB Entry DOI: 10.7270/Q2G44RV5
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50214315
PNG
(CHEMBL90709)
Show SMILES COc1cc(OC)c(cc1Cl)C(=O)CCCCN1CCC2(CC1)NC(=O)NC2=O
Show InChI InChI=1S/C20H26ClN3O5/c1-28-16-12-17(29-2)14(21)11-13(16)15(25)5-3-4-8-24-9-6-20(7-10-24)18(26)22-19(27)23-20/h11-12H,3-10H2,1-2H3,(H2,22,23,26,27)
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0.631n/an/an/an/an/an/an/an/a


TBA

Assay Description
Compound was evaluated for displacement of [3H]mesulergine from cloned rat 5-hydroxytryptamine 2C receptor in transfected CHO-K1 cells.


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098536
PNG
(1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...)
Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F
Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m0/s1
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0.690n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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0.700n/an/an/an/an/an/an/an/a



University of Alberta

Curated by PDSP Ki Database




Neuropharmacology 33: 275-317


BindingDB Entry DOI: 10.7270/Q2M043X2
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50451023
PNG
(MESULERGINE)
Show SMILES CN(C)S(=O)(=O)NC[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1
Show InChI InChI=1S/C19H28N4O2S/c1-21(2)26(24,25)20-10-13-8-16-15-6-5-7-17-19(15)14(12-23(17)4)9-18(16)22(3)11-13/h5-7,12-13,16,18,20H,8-11H2,1-4H3/t13-,16-,18-/m1/s1
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0.730n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Ability to displace [3H]mesulergine bound to 5-hydroxytryptamine 2C receptor in rat cortex


J Med Chem 41: 728-41 (1998)


Article DOI: 10.1021/jm970645i
BindingDB Entry DOI: 10.7270/Q2QV3N6F
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50098533
PNG
(2-Benzo[1,2-b;4,5-b']difuran-4-yl-1-methyl-ethyl-a...)
Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2cc2ccoc12
Show InChI InChI=1S/C13H13NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h2-5,7-8H,6,14H2,1H3/p+1/t8-/m1/s1
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0.790n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand


J Med Chem 44: 1003-10 (2001)


Article DOI: 10.1021/jm000491y
BindingDB Entry DOI: 10.7270/Q27P8XND
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50031942
PNG
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Show SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34
Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1
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0.800n/an/an/an/an/an/an/an/a



Albany Medical College

Curated by PDSP Ki Database




Synapse 35: 144-50 (2000)


Article DOI: 10.1002/(SICI)1098-2396(200002)35:2
BindingDB Entry DOI: 10.7270/Q2ST7NDX
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50031942
PNG
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Show SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34
Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1
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0.800n/an/an/an/an/an/an/an/a



Albany Medical College

Curated by PDSP Ki Database




Ann N Y Acad Sci 861: 140-5 (1998)


Article DOI: 10.1111/cbdd.12663
BindingDB Entry DOI: 10.7270/Q2CV4G8J
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50024204
PNG
(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Show SMILES CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1
Show InChI InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1
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0.900n/an/an/an/an/an/an/an/a



Albany Medical College

Curated by PDSP Ki Database




Ann N Y Acad Sci 861: 140-5 (1998)


Article DOI: 10.1111/cbdd.12663
BindingDB Entry DOI: 10.7270/Q2CV4G8J
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50115831
PNG
(1-Methyl-2-(4-methyl-benzo[1,2-b;5,4-b']difuran-8-...)
Show SMILES CC(N)Cc1c2occc2c(C)c2ccoc12
Show InChI InChI=1S/C14H15NO2/c1-8(15)7-12-13-10(3-5-16-13)9(2)11-4-6-17-14(11)12/h3-6,8H,7,15H2,1-2H3
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0.900n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture


Bioorg Med Chem Lett 12: 1997-9 (2002)


Article DOI: 10.1016/s0960-894x(02)00306-2
BindingDB Entry DOI: 10.7270/Q2BR8RH5
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM50056031
PNG
(CHEMBL104593 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)c2ccncc2)CC1
Show InChI InChI=1S/C19H24N4O2/c1-25-18-5-3-2-4-17(18)23-14-12-22(13-15-23)11-10-21-19(24)16-6-8-20-9-7-16/h2-9H,10-15H2,1H3,(H,21,24)
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0.933n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
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