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Found 1049 Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase'
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134023(CHEMBL337762 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataEC50:  2nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134015(CHEMBL44130 | N-[9-[2-(2-Amino-ethyl)-pyrrolidin-1...)
Affinity DataEC50:  18nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134027(CHEMBL140180 | N,N'-(9-(2-(dimethylamino)ethylamin...)
Affinity DataEC50:  18nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134010(CHEMBL139511 | N,N'-(9-(2-aminophenylamino)acridin...)
Affinity DataEC50:  20nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134011(CHEMBL343609 | N,N'-(9-(2-aminophenylamino)acridin...)
Affinity DataEC50:  21nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50133998(CHEMBL137809 | N,N'-(9-(2-(methylthio)phenylamino)...)
Affinity DataEC50:  30nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50204461(CHEMBL397746 | N-[9-(3,4-difluoro-benzylamino)-6-(...)
Affinity DataEC50:  30nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134022(CHEMBL336444 | N,N'-(9-(4-acetylphenylamino)acridi...)
Affinity DataEC50:  40nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134032(CHEMBL138811 | N,N'-(9-(cyclopropylamino)acridine-...)
Affinity DataEC50:  50nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134021(CHEMBL138761 | N,N'-(9-(3-(methylthio)phenylamino)...)
Affinity DataEC50:  60nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134019(CHEMBL336417 | N,N'-(9-(3-aminophenylamino)acridin...)
Affinity DataEC50:  60nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134009(CHEMBL335132 | N,N'-(9-(3-(dimethylamino)propylami...)
Affinity DataEC50:  60nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180770(3,6-bis[3-(pyrrolidin-1-yl)propionamido]-9-{4'-[3'...)
Affinity DataEC50:  67nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134025(CHEMBL343795 | N,N'-(9-(4-fluorophenylamino)acridi...)
Affinity DataEC50:  70nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134018(CHEMBL335819 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataEC50:  74nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134008(CHEMBL138187 | N,N'-(9-(3-(dimethylamino)propylami...)
Affinity DataEC50:  80nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50150618(CHEMBL182871 | Hexanedioic acid {4-[3,6-bis-(3-pyr...)
Affinity DataEC50:  80nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134000(CHEMBL139287 | N,N'-(9-(cyclohexylamino)acridine-3...)
Affinity DataEC50:  90nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50155654(3,6,9-Tri-pyrrolidin-1-yl-acridine | CHEMBL184103)
Affinity DataEC50:  90nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50150622(CHEMBL184587 | Hexanedioic acid {4-[3,6-bis-(3-pyr...)
Affinity DataEC50:  98nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180768(3,6-[4-(pyrrolidin-1-yl)butanamido]-9-[4'-(N,N-dim...)
Affinity DataEC50:  99nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134020(CHEMBL141661 | N,N'-(9-(3-acetamidophenylamino)acr...)
Affinity DataEC50:  100nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134026(CHEMBL138487 | N,N'-(9-(3-(dimethylamino)phenylami...)
Affinity DataEC50:  100nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataEC50:  113nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataEC50:  113nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataEC50:  115nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180772(3,6-bis[3-(pyrrolidin-1-yl)propionamido]-9-{4'-[3'...)
Affinity DataEC50:  117nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataEC50:  120nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134006(CHEMBL335564 | N,N'-(9-(2-methoxyethylamino)acridi...)
Affinity DataEC50:  140nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180773(3,6-bis[6-(pyrrolidin-1-yl)hexanamido]-9-{4'-[3''-...)
Affinity DataEC50:  146nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50150620(6-(4-Methyl-piperazin-1-yl)-6-oxo-hexanoic acid {4...)
Affinity DataEC50:  165nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180767(3,6-bis[3-(pyrrolidin-1-yl)propionamido]-9-{4'-[2'...)
Affinity DataEC50:  167nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134017(CHEMBL138357 | N,N'-(9-(4-(dimethylamino)phenylami...)
Affinity DataEC50:  170nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50133999(CHEMBL345035 | N,N'-(9-(2-aminophenylamino)acridin...)
Affinity DataEC50:  170nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50155646(3-(4-Hydroxy-piperidin-1-yl)-N-{6-[3-(4-hydroxy-pi...)
Affinity DataEC50:  200nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50155661(3-(4-Methyl-piperidin-1-yl)-N-{6-[3-(4-methyl-pipe...)
Affinity DataEC50:  200nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50155662(3-(2-Hydroxymethyl-piperidin-1-yl)-N-{7-[3-(2-hydr...)
Affinity DataEC50:  200nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134028(CHEMBL142036 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataEC50:  200nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134031(CHEMBL137973 | N,N'-(9-(cyclohexylamino)acridine-2...)
Affinity DataEC50:  210nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134012(CHEMBL342480 | N,N'-(9-(3-aminophenylamino)acridin...)
Affinity DataEC50:  210nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134007(CHEMBL337123 | N-[9-Heptylamino-6-(3-pyrrolidin-1-...)
Affinity DataEC50:  210nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50204464(CHEMBL239793 | N-[9-(3-methyl-benzylamino)-6-(3-pi...)
Affinity DataEC50:  230nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50204466(CHEMBL397768 | N-[9-(3-fluoro-5-trifluoromethyl-be...)
Affinity DataEC50:  240nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180763(3,6-bis[5-(pyrrolidin-1-yl)pentanamido]-9-{4'-[3''...)
Affinity DataEC50:  255nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50150619(6-Morpholin-4-yl-6-oxo-hexanoic acid {4-[3,6-bis-(...)
Affinity DataEC50:  267nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50134001(CHEMBL140084 | N,N'-(9-(2-(dimethylamino)ethylamin...)
Affinity DataEC50:  270nMAssay Description:Inhibitory activity against human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50150621(6-Oxo-6-pyrrolidin-1-yl-hexanoic acid {4-[3,6-bis-...)
Affinity DataEC50:  318nMAssay Description:Effective concentration against telomerase by TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50180766(3,6-bis[4-(pyrrolidin-1-yl)butanamido]-9-{4'-[3''-...)
Affinity DataEC50:  326nMAssay Description:Inhibition of telomerase activity from human A2780 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50204469(CHEMBL397767 | N-[9-(3,5-dimethoxy-benzylamino)-6-...)
Affinity DataEC50:  350nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of London

Curated by ChEMBL
LigandPNGBDBM50204460(CHEMBL396326 | N-[9-(4-dimethylamino-phenylamino)-...)
Affinity DataEC50:  360nMAssay Description:Inhibition of human telomerase by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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