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Found 177 Enz. Inhib. hit(s) with Target = 'Vasoactive intestinal polypeptide receptor 2'
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445117(CHEMBL3102930)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606527(CHEMBL5220770)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at VPAC2 in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at VPAC2 in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50200209(CHEMBL219499)
Affinity DataEC50:  0.0870nMAssay Description:Activity at human VPAC2 receptor in CHO cells by measuring cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445107(CHEMBL3102924)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445122(CHEMBL3102925)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445112(CHEMBL3102919)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445113(CHEMBL1981592)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445118(CHEMBL3102929)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445109(CHEMBL3102922)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445116(CHEMBL3102931)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445110(CHEMBL3102921)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445114(CHEMBL3105020)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50200210(Ac-HSDAVFTDQYTRLRKQVAAKKYLQSIKQKRYC | CHEMBL440082)
Affinity DataEC50:  0.600nMAssay Description:Activity at human VPAC2 receptor in CHO cells by measuring cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445108(CHEMBL3102923)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445121(CHEMBL3102926)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445120(CHEMBL3102927)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445115(CHEMBL3105019)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445119(CHEMBL3102928)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445111(CHEMBL3102920)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at human VPAC2 expressed in CHO Flp-in cells assessed as accumulation of cAMP after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85873(VIP Ala2)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85889(VIP Ala8)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85892(VIP Ala28)
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85871(VIP Ala9)
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85886(VIP Ala24)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85872(VIP Ala19)
Affinity DataKi:  0.430nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85879(VIP Ala16 | VIP Ala6)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85878(VIP Ala21)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85909(VIP Ala27)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85901(VIP Ala20)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85899(VIP Ala25 | VIP Ala26)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85881(VIP Ala15)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM86050(Ac-L-His-L-Ser-L-Asp-L-Ala-L-Val-L-Phe-L-Thr-L-Glu...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85873(VIP Ala2)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85899(VIP Ala25 | VIP Ala26)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85883(VIP Ala13)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85924(VIP Ala17)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85872(VIP Ala19)
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85872(VIP Ala19)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85889(VIP Ala8)
Affinity DataKi:  2.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85873(VIP Ala2)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85871(VIP Ala9)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85886(VIP Ala24)
Affinity DataKi:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85873(VIP Ala2)
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85872(VIP Ala19)
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasoactive intestinal polypeptide receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85873(VIP Ala2)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM85879(VIP Ala16 | VIP Ala6)
Affinity DataKi:  3.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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