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Found 2 hits Enz. Inhib. hit(s) with Target = '3-hydroxyanthranilate 3,4-dioxygenase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-hydroxyanthranilate 3,4-dioxygenase


(Homo sapiens)
BDBM50446510
PNG
(CHEMBL3110069)
Show SMILES Cc1ccc(C(O)=O)c(N)[n+]1[O-]
Show InChI InChI=1S/C7H8N2O3/c1-4-2-3-5(7(10)11)6(8)9(4)12/h2-3H,8H2,1H3,(H,10,11)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of 3-HAO in human brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid scintillation...


Citation and Details
More data for this
Ligand-Target Pair
3-hydroxyanthranilate 3,4-dioxygenase


(Rattus norvegicus)
BDBM50446510
PNG
(CHEMBL3110069)
Show SMILES Cc1ccc(C(O)=O)c(N)[n+]1[O-]
Show InChI InChI=1S/C7H8N2O3/c1-4-2-3-5(7(10)11)6(8)9(4)12/h2-3H,8H2,1H3,(H,10,11)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of 3-HAO in Sprague-Dawley rat brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid ...


Citation and Details
More data for this
Ligand-Target Pair