BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 202 hits Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50088797
PNG
(2-Acetyl-cyclohexane-1,3-dione | CHEMBL167675 | CH...)
Show SMILES CC(=O)C1C(=O)CCCC1=O
Show InChI InChI=1S/C8H10O3/c1-5(9)8-6(10)3-2-4-7(8)11/h8H,2-4H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 0.00631n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403921
PNG
(CHEMBL309664)
Show SMILES ClC1=C(CCCC1=O)OC(=O)C1CC1
Show InChI InChI=1S/C10H11ClO3/c11-9-7(12)2-1-3-8(9)14-10(13)6-4-5-6/h6H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 19.9n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403921
PNG
(CHEMBL309664)
Show SMILES ClC1=C(CCCC1=O)OC(=O)C1CC1
Show InChI InChI=1S/C10H11ClO3/c11-9-7(12)2-1-3-8(9)14-10(13)6-4-5-6/h6H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 20n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072265
PNG
(CHEMBL3408320)
Show SMILES CCn1c2ccc(cc2n(CC)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C16H18N4O3/c1-4-19-12-7-6-10(8-13(12)20(5-2)16(19)23)14(21)11-9-17-18(3)15(11)22/h6-9,22H,4-5H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072237
PNG
(CHEMBL3408314)
Show SMILES CCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C15H16N4O3/c1-4-19-12-7-9(5-6-11(12)17(2)15(19)22)13(20)10-8-16-18(3)14(10)21/h5-8,21H,4H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072264
PNG
(CHEMBL3408319)
Show SMILES CCCn1c2cc(ccc2n(CC)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-4-8-21-14-9-11(6-7-13(14)20(5-2)17(21)24)15(22)12-10-18-19(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089165
PNG
(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Show SMILES O=C(OC1=CC(=O)CCC1)C1CC1
Show InChI InChI=1S/C10H12O3/c11-8-2-1-3-9(6-8)13-10(12)7-4-5-7/h6-7H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 30n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HPPD(4-hydroxyphenylpyruvate Dioxygenase) from pig liver using enol borate assay method


Bioorg Med Chem Lett 10: 1297-8 (2000)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403929
PNG
(CHEMBL76394)
Show SMILES BrC1=C(CCCC1=O)OC(=O)C1CC1
Show InChI InChI=1S/C10H11BrO3/c11-9-7(12)2-1-3-8(9)14-10(13)6-4-5-6/h6H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 30n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089165
PNG
(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Show SMILES O=C(OC1=CC(=O)CCC1)C1CC1
Show InChI InChI=1S/C10H12O3/c11-8-2-1-3-9(6-8)13-10(12)7-4-5-7/h6-7H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 30n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089165
PNG
(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Show SMILES O=C(OC1=CC(=O)CCC1)C1CC1
Show InChI InChI=1S/C10H12O3/c11-8-2-1-3-9(6-8)13-10(12)7-4-5-7/h6-7H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 30n/an/an/an/an/an/a



Tunghai University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration required against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) taken from pig liver


Bioorg Med Chem Lett 13: 927-30 (2003)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089165
PNG
(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Show SMILES O=C(OC1=CC(=O)CCC1)C1CC1
Show InChI InChI=1S/C10H12O3/c11-8-2-1-3-9(6-8)13-10(12)7-4-5-7/h6-7H,1-5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 30.2n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072269
PNG
(CHEMBL3408324)
Show SMILES CCCn1c2ccc(cc2n(CC)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-4-8-21-13-7-6-11(9-14(13)20(5-2)17(21)24)15(22)12-10-18-19(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 39n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50124366
PNG
(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Show SMILES CCOC(=O)C1CC(=O)C(C(=O)C2CC2)=C(C1)OC(=O)C1CC1
Show InChI InChI=1S/C17H20O6/c1-2-22-16(20)11-7-12(18)14(15(19)9-3-4-9)13(8-11)23-17(21)10-5-6-10/h9-11H,2-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 39.8n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075319
PNG
(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 39.8n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075319
PNG
(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50124366
PNG
(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Show SMILES CCOC(=O)C1CC(=O)C(C(=O)C2CC2)=C(C1)OC(=O)C1CC1
Show InChI InChI=1S/C17H20O6/c1-2-22-16(20)11-7-12(18)14(15(19)9-3-4-9)13(8-11)23-17(21)10-5-6-10/h9-11H,2-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50124366
PNG
(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Show SMILES CCOC(=O)C1CC(=O)C(C(=O)C2CC2)=C(C1)OC(=O)C1CC1
Show InChI InChI=1S/C17H20O6/c1-2-22-16(20)11-7-12(18)14(15(19)9-3-4-9)13(8-11)23-17(21)10-5-6-10/h9-11H,2-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Tunghai University

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration required against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) taken from pig liver


Bioorg Med Chem Lett 13: 927-30 (2003)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075319
PNG
(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Tunghai University

Curated by ChEMBL


Assay Description
Inhibition of pig liver 4-Hydroxyphenylpyruvate dioxygenase (4-HPPD) enzyme


J Med Chem 45: 2222-8 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075319
PNG
(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HPPD(4-hydroxyphenylpyruvate Dioxygenase) from pig liver using enol borate assay method


Bioorg Med Chem Lett 10: 1297-8 (2000)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50088804
PNG
(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Show SMILES [O-][N+](=O)c1cc(ccc1C(=O)C1C(=O)CCCC1=O)C(F)(F)F
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate method


Bioorg Med Chem Lett 10: 843-5 (2000)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075319
PNG
(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1
Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 40n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
The inhibitory activity of the compound on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluated.


Bioorg Med Chem Lett 9: 551-4 (1999)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072270
PNG
(CHEMBL3408325)
Show SMILES CCCn1c2ccc(cc2n(CCC)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C18H22N4O3/c1-4-8-21-14-7-6-12(10-15(14)22(9-5-2)18(21)25)16(23)13-11-19-20(3)17(13)24/h6-7,10-11,24H,4-5,8-9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075318
PNG
(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Show SMILES CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1
Show InChI InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
PubMed
n/an/a 44.7n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075318
PNG
(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Show SMILES CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1
Show InChI InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
PubMed
n/an/a 45n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluated


Bioorg Med Chem Lett 9: 551-4 (1999)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50075318
PNG
(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Show SMILES CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1
Show InChI InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
PubMed
n/an/a 50n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072230
PNG
(CHEMBL3408157)
Show SMILES CCCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C16H18N4O3/c1-4-7-20-13-8-10(5-6-12(13)18(2)16(20)23)14(21)11-9-17-19(3)15(11)22/h5-6,8-9,22H,4,7H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072236
PNG
(CHEMBL3408313)
Show SMILES CC(C)n1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C16H18N4O3/c1-9(2)20-13-7-10(5-6-12(13)18(3)16(20)23)14(21)11-8-17-19(4)15(11)22/h5-9,22H,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 61n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072266
PNG
(CHEMBL3408321)
Show SMILES CCn1c2ccc(cc2n(C(C)C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-5-20-13-7-6-11(8-14(13)21(10(2)3)17(20)24)15(22)12-9-18-19(4)16(12)23/h6-10,23H,5H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 64n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072223
PNG
(CHEMBL3408156)
Show SMILES CCC(=O)C(C(C)=O)C(=O)c1ccc(cc1[N+]([O-])=O)C(F)(F)F
Show InChI InChI=1/C14H12F3NO5/c1-3-11(20)12(7(2)19)13(21)9-5-4-8(14(15,16)17)6-10(9)18(22)23/h4-6,12H,3H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403933
PNG
(CHEMBL72081)
Show SMILES O=C(OC1=CC(=O)CC1)C1CC1
Show InChI InChI=1S/C9H10O3/c10-7-3-4-8(5-7)12-9(11)6-1-2-6/h5-6H,1-4H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 71n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072271
PNG
(CHEMBL3408326)
Show SMILES CCCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C19H24N4O3/c1-6-9-22-14-8-7-12(16(24)13-11-20-21(5)17(13)25)10-15(14)23(18(22)26)19(2,3)4/h7-8,10-11,25H,6,9H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403928
PNG
(CHEMBL307048)
Show SMILES CCOC(=O)C1CC(=O)C=C(C1)OC(=O)C1CC1
Show InChI InChI=1S/C13H16O5/c1-2-17-12(15)9-5-10(14)7-11(6-9)18-13(16)8-3-4-8/h7-9H,2-6H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 89.1n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403928
PNG
(CHEMBL307048)
Show SMILES CCOC(=O)C1CC(=O)C=C(C1)OC(=O)C1CC1
Show InChI InChI=1S/C13H16O5/c1-2-17-12(15)9-5-10(14)7-11(6-9)18-13(16)8-3-4-8/h7-9H,2-6H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 90n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072238
PNG
(CHEMBL3408315)
Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(c3c2)C(C)(C)C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-17(2,3)21-13-8-10(6-7-12(13)19(4)16(21)24)14(22)11-9-18-20(5)15(11)23/h6-9,23H,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072263
PNG
(CHEMBL3408318)
Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CC4)c3c2)c1O
Show InChI InChI=1S/C16H16N4O3/c1-18-12-6-3-9(14(21)11-8-17-19(2)15(11)22)7-13(12)20(16(18)23)10-4-5-10/h3,6-8,10,22H,4-5H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089168
PNG
(CHEMBL26162 | Propionic acid 3-oxo-cyclohex-1-enyl...)
Show SMILES CCC(=O)OC1=CC(=O)CCC1
Show InChI InChI=1S/C9H12O3/c1-2-9(11)12-8-5-3-4-7(10)6-8/h6H,2-5H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 110n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403932
PNG
(CHEMBL308315)
Show SMILES O=C(Oc1cc(=O)oc2ccccc12)C1CC1
Show InChI InChI=1S/C13H10O4/c14-12-7-11(17-13(15)8-5-6-8)9-3-1-2-4-10(9)16-12/h1-4,7-8H,5-6H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 110n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089168
PNG
(CHEMBL26162 | Propionic acid 3-oxo-cyclohex-1-enyl...)
Show SMILES CCC(=O)OC1=CC(=O)CCC1
Show InChI InChI=1S/C9H12O3/c1-2-9(11)12-8-5-3-4-7(10)6-8/h6H,2-5H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 110n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50089168
PNG
(CHEMBL26162 | Propionic acid 3-oxo-cyclohex-1-enyl...)
Show SMILES CCC(=O)OC1=CC(=O)CCC1
Show InChI InChI=1S/C9H12O3/c1-2-9(11)12-8-5-3-4-7(10)6-8/h6H,2-5H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 110n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HPPD(4-hydroxyphenylpyruvate Dioxygenase) from pig liver using enol borate assay method


Bioorg Med Chem Lett 10: 1297-8 (2000)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50403932
PNG
(CHEMBL308315)
Show SMILES O=C(Oc1cc(=O)oc2ccccc12)C1CC1
Show InChI InChI=1S/C13H10O4/c14-12-7-11(17-13(15)8-5-6-8)9-3-1-2-4-10(9)16-12/h1-4,7-8H,5-6H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 110n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072240
PNG
(CHEMBL3408317)
Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(Cc4ccccc4)c3c2)c1O
Show InChI InChI=1S/C20H18N4O3/c1-22-16-9-8-14(18(25)15-11-21-23(2)19(15)26)10-17(16)24(20(22)27)12-13-6-4-3-5-7-13/h3-11,26H,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072235
PNG
(CHEMBL3408312)
Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CCCC4)c3c2)c1O
Show InChI InChI=1S/C18H20N4O3/c1-20-14-8-7-11(16(23)13-10-19-21(2)17(13)24)9-15(14)22(18(20)25)12-5-3-4-6-12/h7-10,12,24H,3-6H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072232
PNG
(CHEMBL3408311)
Show SMILES CC(C)Cn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-10(2)9-21-14-7-11(5-6-13(14)19(3)17(21)24)15(22)12-8-18-20(4)16(12)23/h5-8,10,23H,9H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072267
PNG
(CHEMBL3408322)
Show SMILES CCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C18H22N4O3/c1-6-21-13-8-7-11(15(23)12-10-19-20(5)16(12)24)9-14(13)22(17(21)25)18(2,3)4/h7-10,24H,6H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50113304
PNG
(3-Hydroxy-2-(2-nitro-benzoyl)-cyclohex-2-enone | C...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccccc2[N+]([O-])=O)C(=O)CCC1
Show InChI InChI=1S/C13H11NO5/c15-10-6-3-7-11(16)12(10)13(17)8-4-1-2-5-9(8)14(18)19/h1-2,4-5,15H,3,6-7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 158n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50088793
PNG
(2-(2-Nitro-benzoyl)-cyclohexane-1,3-dione | CHEMBL...)
Show SMILES [O-][N+](=O)c1ccccc1C(=O)C1C(=O)CCCC1=O
Show InChI InChI=1S/C13H11NO5/c15-10-6-3-7-11(16)12(10)13(17)8-4-1-2-5-9(8)14(18)19/h1-2,4-5,12H,3,6-7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 160n/an/an/an/an/an/a



Tunghai Christian University

Curated by ChEMBL


Assay Description
Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate method


Bioorg Med Chem Lett 10: 843-5 (2000)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50113304
PNG
(3-Hydroxy-2-(2-nitro-benzoyl)-cyclohex-2-enone | C...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccccc2[N+]([O-])=O)C(=O)CCC1
Show InChI InChI=1S/C13H11NO5/c15-10-6-3-7-11(16)12(10)13(17)8-4-1-2-5-9(8)14(18)19/h1-2,4-5,15H,3,6-7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 160n/an/an/an/an/an/a



Tunghai University

Curated by ChEMBL


Assay Description
Inhibition of pig liver 4-Hydroxyphenylpyruvate dioxygenase (4-HPPD) enzyme


J Med Chem 45: 2222-8 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Sus scrofa)
BDBM50113304
PNG
(3-Hydroxy-2-(2-nitro-benzoyl)-cyclohex-2-enone | C...)
Show SMILES [O-]C1=C(C(=[OH+])c2ccccc2[N+]([O-])=O)C(=O)CCC1
Show InChI InChI=1S/C13H11NO5/c15-10-6-3-7-11(16)12(10)13(17)8-4-1-2-5-9(8)14(18)19/h1-2,4-5,15H,3,6-7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 160n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver


Bioorg Med Chem Lett 12: 2271-5 (2002)

More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072231
PNG
(CHEMBL3408310)
Show SMILES CCCCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H20N4O3/c1-4-5-8-21-14-9-11(6-7-13(14)19(2)17(21)24)15(22)12-10-18-20(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase


(Homo sapiens)
BDBM50072268
PNG
(CHEMBL3408323)
Show SMILES CCn1c2ccc(cc2n(C2CC2)c1=O)C(=O)c1cnn(C)c1O
Show InChI InChI=1S/C17H18N4O3/c1-3-20-13-7-4-10(15(22)12-9-18-19(2)16(12)23)8-14(13)21(17(20)24)11-5-6-11/h4,7-9,11,23H,3,5-6H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Central China Normal University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 202 total )  |  Next  |  Last  >>
Jump to: