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Found 5 hits Enz. Inhib. hit(s) with Target = '5-Lipoxygenase (5-LOX)'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Lipoxygenase (5-LOX)


(Glycine max (Soybean))
BDBM192705
PNG
(7-(2-hydroxy-3-(6-methoxybenzo[d]thiazol-2-ylamino...)
Show SMILES COc1ccc2nc(NCC(O)COc3ccc4c(C)cc(=O)oc4c3)sc2c1
Show InChI InChI=1/C21H20N2O5S/c1-12-7-20(25)28-18-8-15(3-5-16(12)18)27-11-13(24)10-22-21-23-17-6-4-14(26-2)9-19(17)29-21/h3-9,13,24H,10-11H2,1-2H3,(H,22,23)
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PC sid
UniChem

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Article
PubMed
n/an/a 2.12n/an/an/an/an/an/a



Nirma University



Assay Description
It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...


Citation and Details
More data for this
Ligand-Target Pair
5-Lipoxygenase (5-LOX)


(Glycine max (Soybean))
BDBM192703
PNG
(7-(3-(6-chlorobenzo[d]thiazol-2-ylamino)-2-hydroxy...)
Show SMILES Cc1cc(=O)oc2cc(OCC(O)CNc3nc4ccc(Cl)cc4s3)ccc12
Show InChI InChI=1/C20H17ClN2O4S/c1-11-6-19(25)27-17-8-14(3-4-15(11)17)26-10-13(24)9-22-20-23-16-5-2-12(21)7-18(16)28-20/h2-8,13,24H,9-10H2,1H3,(H,22,23)
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PC sid
UniChem

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Article
PubMed
n/an/a 2.79n/an/an/an/an/an/a



Nirma University



Assay Description
It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...


Citation and Details
More data for this
Ligand-Target Pair
5-Lipoxygenase (5-LOX)


(Glycine max (Soybean))
BDBM192701
PNG
(7-(2-hydroxy-3-(6-nitrobenzo[d]thiazol-2-ylamino)p...)
Show SMILES Cc1cc(=O)oc2cc(OCC(O)CNc3nc4ccc(cc4s3)[N+]([O-])=O)ccc12
Show InChI InChI=1/C20H17N3O6S/c1-11-6-19(25)29-17-8-14(3-4-15(11)17)28-10-13(24)9-21-20-22-16-5-2-12(23(26)27)7-18(16)30-20/h2-8,13,24H,9-10H2,1H3,(H,21,22)
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Article
PubMed
n/an/a 3.24n/an/an/an/an/an/a



Nirma University



Assay Description
It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...


Citation and Details
More data for this
Ligand-Target Pair
5-Lipoxygenase (5-LOX)


(Glycine max (Soybean))
BDBM192702
PNG
(7-(3-(5-chloro-6-fluorobenzo[d]thiazol-2-ylamino)-...)
Show SMILES Cc1cc(=O)oc2cc(OCC(O)CNc3nc4cc(Cl)c(F)cc4s3)ccc12
Show InChI InChI=1/C20H16ClFN2O4S/c1-10-4-19(26)28-17-5-12(2-3-13(10)17)27-9-11(25)8-23-20-24-16-6-14(21)15(22)7-18(16)29-20/h2-7,11,25H,8-9H2,1H3,(H,23,24)
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UniChem

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Article
PubMed
n/an/a 6.16n/an/an/an/an/an/a



Nirma University



Assay Description
It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...


Citation and Details
More data for this
Ligand-Target Pair
5-Lipoxygenase (5-LOX)


(Glycine max (Soybean))
BDBM192704
PNG
(7-(3-(5,6-dichlorobenzo[d]thiazol-2-ylamino)-2-hyd...)
Show SMILES Cc1cc(=O)oc2cc(OCC(O)CNc3nc4cc(Cl)c(Cl)cc4s3)ccc12
Show InChI InChI=1/C20H16Cl2N2O4S/c1-10-4-19(26)28-17-5-12(2-3-13(10)17)27-9-11(25)8-23-20-24-16-6-14(21)15(22)7-18(16)29-20/h2-7,11,25H,8-9H2,1H3,(H,23,24)
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PC sid
UniChem

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Article
PubMed
n/an/a 15.5n/an/an/an/an/an/a



Nirma University



Assay Description
It is determined by kinetic mode of spectro-photometric determination method,which was performed by recording the rate of change in absorbance at 234...


Citation and Details
More data for this
Ligand-Target Pair