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Found 193 hits Enz. Inhib. hit(s) with Target = 'AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431029
PNG
(CHEMBL574646)
Show SMILES O=C1\C(CNC\C1=C/c1ccccn1)=C\c1ccccn1
Show InChI InChI=1S/C17H15N3O/c21-17-13(9-15-5-1-3-7-19-15)11-18-12-14(17)10-16-6-2-4-8-20-16/h1-10,18H,11-12H2/b13-9+,14-10+
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431028
PNG
(CHEMBL2338333)
Show SMILES CN1C\C(=C/c2ccccn2)C(=O)\C(C1)=C\c1ccccn1
Show InChI InChI=1S/C18H17N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-11H,12-13H2,1H3/b14-10+,15-11+
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50389320
PNG
(CHEMBL2063926)
Show SMILES CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCN(CC1)C1CCNCC1
Show InChI InChI=1S/C26H35N9S/c1-36-21-5-3-2-4-20(21)31-25-22-23(24(30-17-29-22)28-16-18-6-7-18)32-26(33-25)35-14-12-34(13-15-35)19-8-10-27-11-9-19/h2-5,17-19,27H,6-16H2,1H3,(H,28,29,30)(H,31,32,33)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a<1.00E+4n/an/an/an/an/an/a



Janssen Pharmaceutical Companies of Johnson& Johnson

Curated by ChEMBL


Assay Description
Inhibition of AMPK A1/B1/G1 by FRET assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431025
PNG
(CHEMBL2338335)
Show SMILES CN1C[C@H](Cc2ccccn2)C(=O)C(C1)=Cc1ccccn1
Show InChI InChI=1S/C18H19N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-10,15H,11-13H2,1H3/t15-/m0/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431026
PNG
(CHEMBL2338334)
Show SMILES CN1C[C@@H](Cc2ccccn2)C(=O)C(C1)=Cc1ccccn1
Show InChI InChI=1S/C18H19N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-10,15H,11-13H2,1H3/t15-/m1/s1
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431027
PNG
(CHEMBL2036343)
Show SMILES O=C1\C(CSC\C1=C/c1ccccn1)=C\c1ccccn1
Show InChI InChI=1S/C17H14N2OS/c20-17-13(9-15-5-1-3-7-18-15)11-21-12-14(17)10-16-6-2-4-8-19-16/h1-10H,11-12H2/b13-9+,14-10+
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM50431030
PNG
(CHEMBL379849)
Show SMILES Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
Show InChI InChI=1S/C19H15F2NO/c20-17-7-3-1-5-13(17)9-15-11-22-12-16(19(15)23)10-14-6-2-4-8-18(14)21/h1-10,22H,11-12H2/b15-9+,16-10+
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237920
PNG
(US9394285, 1)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 4.20n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237921
PNG
(US9394285, 2)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 64.7n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237922
PNG
(US9394285, 3)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 459n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237923
PNG
(US9394285, 4)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 71n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237924
PNG
(US9394285, 5)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 35.7n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237925
PNG
(US9394285, 6)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 17.3n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237926
PNG
(US9394285, 7)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 671n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237927
PNG
(US9394285, 8)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 220n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237928
PNG
(US9394285, 9)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 71.2n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237929
PNG
(US9394285, 10)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 69.9n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237930
PNG
(US9394285, 11)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 554n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237931
PNG
(US9394285, 12)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 42.5n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237932
PNG
(US9394285, 13)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 6.90n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237933
PNG
(US9394285, 14 | US9394285, 14A | US9394285, 14B)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 151n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237933
PNG
(US9394285, 14 | US9394285, 14A | US9394285, 14B)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 101n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237933
PNG
(US9394285, 14 | US9394285, 14A | US9394285, 14B)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 118n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237934
PNG
(US9394285, 15)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 632n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237935
PNG
(US9394285, 16)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 412n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237936
PNG
(US9394285, 17)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 126n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237937
PNG
(US9394285, 18)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 182n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237938
PNG
(US9394285, 19)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 383n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237939
PNG
(US9394285, 20)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 53.6n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237940
PNG
(US9394285, 21)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 93.5n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237941
PNG
(US9394285, 22)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 13.7n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237942
PNG
(US9394285, 23)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 16n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237943
PNG
(US9394285, 24)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 252n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237944
PNG
(US9394285, 25)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 111n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM60975
PNG
(4,6-difluoro-5-[4-(1-hydroxy-2-methylpropan-2-yl)p...)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
n/an/an/an/a 125n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237946
PNG
(US9394285, 27)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 36.9n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237947
PNG
(US9394285, 28)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 1.08E+3n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237948
PNG
(US9394285, 29)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 383n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237949
PNG
(US9394285, 30)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 30n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237950
PNG
(US9394285, 31)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 130n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237951
PNG
(US9394285, 32)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 570n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237952
PNG
(US9394285, 33)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 85.3n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237953
PNG
(US9394285, 34)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 315n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237954
PNG
(US9394285, 35)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 74.2n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237955
PNG
(US9394285, 36)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 7.10n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237956
PNG
(US9394285, 37)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 248n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237957
PNG
(US9394285, 38)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 106n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237958
PNG
(US9394285, 39)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 11.1n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237959
PNG
(US9394285, 40)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 821n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1


(Homo sapiens-Homo sapiens (Human))
BDBM237960
PNG
(US9394285, 41)
GoogleScholar
AffyNet 
UniChem
AffyNet 
n/an/an/an/a 9.60n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
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