BindingDB PrimarySearch

Found 199 hits Enz. Inhib. hit(s) with Target = 'ATP-citrate synthase'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-citrate synthase (Rattus norvegicus)	BDBM50469147 (CHEMBL4281691) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	KEGG UniChem	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				Eur J Med Chem 157: 1276-1291 (2018)
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50469153 (CHEMBL4292319) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	KEGG UniChem	PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				Eur J Med Chem 157: 1276-1291 (2018)
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209010 (3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50036210 ((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...) Show SMILES O[C@H](C(O)=O)[C@@](O)(CC(O)=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209015 (3,5-dichloro-2-hydroxy-N-(2,4,6-triphenylphenyl)be...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50394674 (CHEMBL2165254) Show SMILES Cc1cc(O)c2C(=O)c3c(O)c(Cl)c(O)cc3Cc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY by MDH enzyme coupled assay				Eur J Med Chem 157: 1276-1291 (2018)
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50394674 (CHEMBL2165254) Show SMILES Cc1cc(O)c2C(=O)c3c(O)c(Cl)c(O)cc3Cc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of Wistar rat liver ATP citrate lyase using tripotassium citrate as substrate by malate dehydrogenase-based oxaloacetate reduction assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50394674 (CHEMBL2165254) Show SMILES Cc1cc(O)c2C(=O)c3c(O)c(Cl)c(O)cc3Cc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209014 ((Z)-3-phenylallyl 2-(3,5-dichloro-2-hydroxyphenyls...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209009 (2-isopropyl-5-methylcyclohexyl 2-(3,5-dichloro-2-h...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209010 (3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assay				Bioorg Med Chem Lett 27: 929-935 (2017) Article DOI: 10.1016/j.bmcl.2017.01.001 BindingDB Entry DOI: 10.7270/Q2MP55HS
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209010 (3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	442	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209018 (3,5-dichloro-N-(3,5-di-tert-butylphenyl)-2-hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209013 (3,5-dichloro-N-(3,5-dichlorophenyl)-2-hydroxybenze...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234009 (CHEMBL3261914) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234013 (CHEMBL4084819) Show SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)c(Cl)c3Cc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234436 (CHEMBL4094117) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assay				Bioorg Med Chem Lett 27: 929-935 (2017) Article DOI: 10.1016/j.bmcl.2017.01.001 BindingDB Entry DOI: 10.7270/Q2MP55HS
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209008 (3,5-dichloro-N-(2,5-di-tert-butylphenyl)-2-hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209012 (3,5-dichloro-N-(4-hexylphenyl)-2-hydroxybenzenesul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50394675 (PURPURONE) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50394675 (PURPURONE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of ACLY (unknown origin)				Eur J Med Chem 157: 1276-1291 (2018)
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234008 (CHEMBL3261915) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209007 (3,5-dichloro-N-(3,5-difluorophenyl)-2-hydroxybenze...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209017 (3,5-dichloro-2-hydroxy-N-(3-phenoxyphenyl)benzenes...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234010 (CHEMBL4065663) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50209011 (CHEMBL250744 \| N-(4-(3,5-dichloro-2-hydroxyphenyls...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234438 (CHEMBL4072433) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assay				Bioorg Med Chem Lett 27: 929-935 (2017) Article DOI: 10.1016/j.bmcl.2017.01.001 BindingDB Entry DOI: 10.7270/Q2MP55HS
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234016 (CHEMBL4093300) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234012 (CHEMBL4062121) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234437 (CHEMBL4061755) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assay				Bioorg Med Chem Lett 27: 929-935 (2017) Article DOI: 10.1016/j.bmcl.2017.01.001 BindingDB Entry DOI: 10.7270/Q2MP55HS
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234006 (CHEMBL4104369) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234011 (CHEMBL4091629) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234007 (CHEMBL4103478) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234017 (CHEMBL4083854) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234018 (CHEMBL4099000) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234014 (CHEMBL4072039) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50234015 (CHEMBL4095719) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate after 60 mins by ADP-Glo luminescence assay				Eur J Med Chem 126: 920-928 (2017) Article DOI: 10.1016/j.ejmech.2016.12.018 BindingDB Entry DOI: 10.7270/Q2028TSK
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50036210 ((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...) Show SMILES O[C@H](C(O)=O)[C@@](O)(CC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-citrate synthase (Rattus norvegicus)	BDBM50036210 ((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...) Show SMILES O[C@H](C(O)=O)[C@@](O)(CC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrate				J Med Chem 38: 537-43 (1995) Article DOI: 10.1021/jm00003a016 BindingDB Entry DOI: 10.7270/Q21Z43GM
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066694 ((S)-2-[(R)-7-(3-Chloro-9H-fluoren-9-yl)-2-hydroxy-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human ACLY				Eur J Med Chem 157: 1276-1291 (2018)
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50394668 (CHEMBL2163366) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066694 ((S)-2-[(R)-7-(3-Chloro-9H-fluoren-9-yl)-2-hydroxy-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066677 ((S)-2-{(R)-8-[4-Chloro-2-(3,4-dimethyl-pyrrol-1-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50394671 (CHEMBL2165260) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066677 ((S)-2-{(R)-8-[4-Chloro-2-(3,4-dimethyl-pyrrol-1-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50394671 (CHEMBL2165260) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066673 ((S)-2-[(R)-7-(5-Chloro-2-phenyl-indol-1-yl)-2-hydr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50394670 (CHEMBL2165263) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066676 ((2S,3R)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-o...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

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