BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'ATP-dependent DNA helicase Q1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440527
PNG
(CHEMBL2426164)
Show SMILES Brc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9BrN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440538
PNG
(CHEMBL2426174)
Show SMILES O=C(Nc1nnc(s1)-c1ccncc1)Nc1ccc(-c2cn[nH]c2)c(c1)C#N
Show InChI InChI=1S/C18H12N8OS/c19-8-12-7-14(1-2-15(12)13-9-21-22-10-13)23-17(27)24-18-26-25-16(28-18)11-3-5-20-6-4-11/h1-7,9-10H,(H,21,22)(H2,23,24,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440533
PNG
(CHEMBL2426169)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9FN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Citation and Details
Checked by Author
More data for this
Ligand-Target Pair