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Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with Target = 'Activating transcription factor 1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Activating transcription factor 1


(Homo sapiens)
BDBM50062648
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C14H5ClF9N3O/c15-11-25-4-8(9(27-11)14(22,23)24)10(28)26-7-2-5(12(16,17)18)1-6(3-7)13(19,20)21/h1-4H,(H,26,28)
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n/an/a 50n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062645
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES CCCCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C18H14ClF6N3O3/c1-2-3-4-31-15(30)9-5-10(17(20,21)22)7-11(6-9)27-14(29)12-8-26-16(19)28-13(12)18(23,24)25/h5-8H,2-4H2,1H3,(H,27,29)
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n/an/a 120n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062658
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES CCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C16H10ClF6N3O3/c1-2-29-13(28)7-3-8(15(18,19)20)5-9(4-7)25-12(27)10-6-24-14(17)26-11(10)16(21,22)23/h3-6H,2H2,1H3,(H,25,27)
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n/an/a 150n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062669
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1ccc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc1
Show InChI InChI=1S/C13H6ClF6N3O/c14-11-21-5-8(9(23-11)13(18,19)20)10(24)22-7-3-1-6(2-4-7)12(15,16)17/h1-5H,(H,22,24)
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n/an/a 490n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062661
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C12H5Cl3F3N3O/c13-5-1-6(14)3-7(2-5)20-10(22)8-4-19-11(15)21-9(8)12(16,17)18/h1-4H,(H,20,22)
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n/an/a 500n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062663
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)nc(Cl)n1
Show InChI InChI=1S/C10H3Cl3F3N5O/c11-4-1-5(20-9(13)18-4)19-7(22)3-2-17-8(12)21-6(3)10(14,15)16/h1-2H,(H,18,19,20,22)
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n/an/a 500n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062653
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES CCCCCCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C20H18ClF6N3O3/c1-2-3-4-5-6-33-17(32)11-7-12(19(22,23)24)9-13(8-11)29-16(31)14-10-28-18(21)30-15(14)20(25,26)27/h7-10H,2-6H2,1H3,(H,29,31)
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n/an/a 660n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062650
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)c(Cl)c(Cl)c1
Show InChI InChI=1S/C12H4Cl4F3N3O/c13-6-1-4(2-7(14)8(6)15)21-10(23)5-3-20-11(16)22-9(5)12(17,18)19/h1-3H,(H,21,23)
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n/an/a 900n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062656
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES CCCCCCCCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C22H22ClF6N3O3/c1-2-3-4-5-6-7-8-35-19(34)13-9-14(21(24,25)26)11-15(10-13)31-18(33)16-12-30-20(23)32-17(16)22(27,28)29/h9-12H,2-8H2,1H3,(H,31,33)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062651
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(=O)OC1CCCCC1
Show InChI InChI=1S/C20H16ClF6N3O3/c21-18-28-9-14(15(30-18)20(25,26)27)16(31)29-12-7-10(6-11(8-12)19(22,23)24)17(32)33-13-4-2-1-3-5-13/h6-9,13H,1-5H2,(H,29,31)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062672
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES COc1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(OC)c1
Show InChI InChI=1S/C14H11ClF3N3O3/c1-23-8-3-7(4-9(5-8)24-2)20-12(22)10-6-19-13(15)21-11(10)14(16,17)18/h3-6H,1-2H3,(H,20,22)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062649
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)N(Cc1ccccc1)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C19H11Cl3F3N3O/c20-12-6-13(21)8-14(7-12)28(10-11-4-2-1-3-5-11)17(29)15-9-26-18(22)27-16(15)19(23,24)25/h1-9H,10H2
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n/an/a 2.70E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062673
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES Cc1ccc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)s1
Show InChI InChI=1S/C11H7ClF3N3OS/c1-5-2-3-7(20-5)17-9(19)6-4-16-10(12)18-8(6)11(13,14)15/h2-4H,1H3,(H,17,19)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062652
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES CN(C(=O)c1cnc(Cl)nc1C(F)(F)F)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C13H7Cl3F3N3O/c1-22(8-3-6(14)2-7(15)4-8)11(23)9-5-20-12(16)21-10(9)13(17,18)19/h2-5H,1H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062671
PNG
(3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...)
Show SMILES CCOP(=O)(COC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F)OCC
Show InChI InChI=1S/C19H17ClF6N3O6P/c1-3-34-36(32,35-4-2)9-33-16(31)10-5-11(18(21,22)23)7-12(6-10)28-15(30)13-8-27-17(20)29-14(13)19(24,25)26/h5-8H,3-4,9H2,1-2H3,(H,28,30)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062674
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES NC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C14H7ClF6N4O2/c15-12-23-4-8(9(25-12)14(19,20)21)11(27)24-7-2-5(10(22)26)1-6(3-7)13(16,17)18/h1-4H,(H2,22,26)(H,24,27)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062659
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES Cc1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)on1
Show InChI InChI=1S/C10H6ClF3N4O2/c1-4-2-6(20-18-4)16-8(19)5-3-15-9(11)17-7(5)10(12,13)14/h2-3H,1H3,(H,16,19)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062668
PNG
(2-Piperidin-1-yl-4-trifluoromethyl-pyrimidine-5-ca...)
Show SMILES FC(F)(F)c1nc(ncc1C(=O)Nc1cc(Cl)cc(Cl)c1)N1CCCCC1
Show InChI InChI=1S/C17H15Cl2F3N4O/c18-10-6-11(19)8-12(7-10)24-15(27)13-9-23-16(25-14(13)17(20,21)22)26-4-2-1-3-5-26/h6-9H,1-5H2,(H,24,27)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062647
PNG
(2-Butylamino-4-trifluoromethyl-pyrimidine-5-carbox...)
Show SMILES CCCCNc1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F
Show InChI InChI=1S/C16H15Cl2F3N4O/c1-2-3-4-22-15-23-8-12(13(25-15)16(19,20)21)14(26)24-11-6-9(17)5-10(18)7-11/h5-8H,2-4H2,1H3,(H,24,26)(H,22,23,25)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062654
PNG
(2-Phenylamino-4-trifluoromethyl-pyrimidine-5-carbo...)
Show SMILES FC(F)(F)c1nc(Nc2ccccc2)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H11Cl2F3N4O/c19-10-6-11(20)8-13(7-10)25-16(28)14-9-24-17(27-15(14)18(21,22)23)26-12-4-2-1-3-5-12/h1-9H,(H,25,28)(H,24,26,27)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062665
PNG
(2-Dimethylamino-4-trifluoromethyl-pyrimidine-5-car...)
Show SMILES CN(C)c1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F
Show InChI InChI=1S/C14H11Cl2F3N4O/c1-23(2)13-20-6-10(11(22-13)14(17,18)19)12(24)21-9-4-7(15)3-8(16)5-9/h3-6H,1-2H3,(H,21,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062666
PNG
(2-Amino-4-trifluoromethyl-pyrimidine-5-carboxylic ...)
Show SMILES Nc1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F
Show InChI InChI=1S/C12H7Cl2F3N4O/c13-5-1-6(14)3-7(2-5)20-10(22)8-4-19-11(18)21-9(8)12(15,16)17/h1-4H,(H,20,22)(H2,18,19,21)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062670
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C12H7ClF3N3O/c13-11-17-6-8(9(19-11)12(14,15)16)10(20)18-7-4-2-1-3-5-7/h1-6H,(H,18,20)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062660
PNG
(2-Methoxy-4-trifluoromethyl-pyrimidine-5-carboxyli...)
Show SMILES COc1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F
Show InChI InChI=1S/C13H8Cl2F3N3O2/c1-23-12-19-5-9(10(21-12)13(16,17)18)11(22)20-8-3-6(14)2-7(15)4-8/h2-5H,1H3,(H,20,22)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062664
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES CCCCNC(=O)c1cnc(Cl)nc1C(F)(F)F
Show InChI InChI=1S/C10H11ClF3N3O/c1-2-3-4-15-8(18)6-5-16-9(11)17-7(6)10(12,13)14/h5H,2-4H2,1H3,(H,15,18)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062662
PNG
(2-Cyclohexylamino-4-trifluoromethyl-pyrimidine-5-c...)
Show SMILES FC(F)(F)c1nc(NC2CCCCC2)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H17Cl2F3N4O/c19-10-6-11(20)8-13(7-10)25-16(28)14-9-24-17(27-15(14)18(21,22)23)26-12-4-2-1-3-5-12/h6-9,12H,1-5H2,(H,25,28)(H,24,26,27)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062655
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES CCCCNC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C18H15ClF6N4O2/c1-2-3-4-26-14(30)9-5-10(17(20,21)22)7-11(6-9)28-15(31)12-8-27-16(19)29-13(12)18(23,24)25/h5-8H,2-4H2,1H3,(H,26,30)(H,28,31)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062646
PNG
(2-Benzylamino-4-trifluoromethyl-pyrimidine-5-carbo...)
Show SMILES FC(F)(F)c1nc(NCc2ccccc2)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C19H13Cl2F3N4O/c20-12-6-13(21)8-14(7-12)27-17(29)15-10-26-18(28-16(15)19(22,23)24)25-9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,27,29)(H,25,26,28)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062667
PNG
(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Show SMILES Cc1cccc(C)c1NC(=O)c1cnc(Cl)nc1C(F)(F)F
Show InChI InChI=1S/C14H11ClF3N3O/c1-7-4-3-5-8(2)10(7)20-12(22)9-6-19-13(15)21-11(9)14(16,17)18/h3-6H,1-2H3,(H,20,22)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062657
PNG
(4-Trifluoromethyl-pyrimidine-5-carboxylic acid (3,...)
Show SMILES FC(F)(F)c1ncncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C12H6Cl2F3N3O/c13-6-1-7(14)3-8(2-6)20-11(21)9-4-18-5-19-10(9)12(15,16)17/h1-5H,(H,20,21)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair
Activating transcription factor 1


(Homo sapiens)
BDBM50062644
PNG
(2-Hydroxy-4-trifluoromethyl-pyrimidine-5-carboxyli...)
Show SMILES FC(F)(F)c1[nH]c(=O)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C12H6Cl2F3N3O2/c13-5-1-6(14)3-7(2-5)19-10(21)8-4-18-11(22)20-9(8)12(15,16)17/h1-4H,(H,19,21)(H,18,20,22)
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Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


Citation and Details
More data for this
Ligand-Target Pair