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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase tissue-nonspecific'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase tissue-nonspecific


(Rattus norvegicus)
BDBM50404870
PNG
(CHEMBL350836)
Show SMILES OC(=O)c1ccc2nc3ccc(O)cc3c(=O)n2c1
Show InChI InChI=1S/C13H8N2O4/c16-8-2-3-10-9(5-8)12(17)15-6-7(13(18)19)1-4-11(15)14-10/h1-6,16H,(H,18,19)
KEGG

UniProtKB/SwissProt

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PC sid
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PubMed
n/an/a 3.40E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of human leukocyte alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrate


J Med Chem 25: 742-5 (1982)

More data for this
Ligand-Target Pair
Alkaline phosphatase tissue-nonspecific


(Rattus norvegicus)
BDBM14363
PNG
(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Show SMILES CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1
Show InChI InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)
KEGG

UniProtKB/SwissProt

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PubMed
n/an/a 1.75E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of human leukocyte alkaline phosphatase in the presence of 10 mM p-nitrophenyl phosphate as substrate


J Med Chem 25: 742-5 (1982)

More data for this
Ligand-Target Pair
Alkaline phosphatase tissue-nonspecific


(Rattus norvegicus)
BDBM50131868
PNG
(7-Phosphonomethyl-naphthalene-1-carboxylic acid | ...)
Show SMILES OC(=O)c1cccc2ccc(CP(O)(O)=O)cc12
Show InChI InChI=1S/C12H11O5P/c13-12(14)10-3-1-2-9-5-4-8(6-11(9)10)7-18(15,16)17/h1-6H,7H2,(H,13,14)(H2,15,16,17)
KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
3.00E+5n/an/an/an/an/an/an/an/a



Utah State University

Curated by ChEMBL


Assay Description
Inhibitory activity against E. coli Alkaline Phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase tissue-nonspecific


(Rattus norvegicus)
BDBM50131864
PNG
(CHEMBL125296 | Propyl-phosphonic acid)
Show SMILES CCCP(O)(O)=O
Show InChI InChI=1S/C3H9O3P/c1-2-3-7(4,5)6/h2-3H2,1H3,(H2,4,5,6)
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
6.10E+5n/an/an/an/an/an/an/an/a



Utah State University

Curated by ChEMBL


Assay Description
Inhibitory activity against E. coli Alkaline Phosphatase


Citation and Details
More data for this
Ligand-Target Pair