Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Homo sapiens) | BDBM50439246![]() (CHEMBL2418830) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439247![]() (CHEMBL2418831) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439245![]() (CHEMBL2418991) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439244![]() (CHEMBL2418829) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427899![]() (CHEMBL2326090) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439242![]() (CHEMBL2418828) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427903![]() (CHEMBL2326087) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439243![]() (CHEMBL2418998) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439241![]() (CHEMBL2418999) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427904![]() (CHEMBL2326086) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427911![]() (CHEMBL2326095) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439240![]() (CHEMBL2418993) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439238![]() (CHEMBL2418995) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439239![]() (CHEMBL2418994) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439237![]() (CHEMBL2418996) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427909![]() (CHEMBL2326097) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439236![]() (CHEMBL2418997) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427900![]() ((R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]he...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 223 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427913![]() (CHEMBL2326093) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427910![]() (CHEMBL2326096) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427907![]() (CHEMBL2326099) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427905![]() (CHEMBL2326085) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427911![]() (CHEMBL2326095) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427911![]() (CHEMBL2326095) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439233![]() (CHEMBL2418827) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427913![]() (CHEMBL2326093) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439235![]() (CHEMBL2418992) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427912![]() (CHEMBL2326094) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427905![]() (CHEMBL2326085) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427906![]() (CHEMBL2326084) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439234![]() (CHEMBL2418826) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50350311![]() (CHEMBL1812661) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human Arg1 | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427914![]() (CHEMBL2326092) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50350311![]() (CHEMBL1812661) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427901![]() (CHEMBL2326088) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50350311![]() (CHEMBL1812661) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427908![]() (CHEMBL2326098) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Rattus norvegicus) | BDBM50008099![]() (CHEMBL1234777) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars AffyNet ![]() | PDB Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Inhibition of rat liver arginase | Eur J Med Chem 76: 132-44 (2014) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431953![]() (CHEMBL2348490) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431958![]() (CHEMBL2348496) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431954![]() (CHEMBL2348492) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 2.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427900![]() ((R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]he...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human arginase 1 transfected in CHO cells assessed as inhibition of urea formation after 24 hrs by spectrophotometric analysis | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431952![]() (CHEMBL2348491) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50350309![]() (CHEMBL1812662) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431961![]() (CHEMBL2348498) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431955![]() (CHEMBL2348493) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431951![]() (CHEMBL2348489) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50439248![]() (CHEMBL2419000) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 6.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 4837-41 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50427901![]() (CHEMBL2326088) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human arginase 1 transfected in CHO cells assessed as inhibition of urea formation after 24 hrs by spectrophotometric analysis | J Med Chem 56: 2568-80 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens) | BDBM50431959![]() (CHEMBL2348497) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) | |||||||||||
More data for this Ligand-Target Pair |
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