Compile Data Set for Download or QSAR

Found 138 hits Enz. Inhib. hit(s) with Target = 'Arginase-1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM50439246 (CHEMBL2418830) Show SMILES NC(CCCCB(O)O)(C1CC2CCC(C1)N2Cc1ccc(Cl)cc1)C(O)=O Show InChI InChI=1/C20H30BClN2O4/c22-16-5-3-14(4-6-16)13-24-17-7-8-18(24)12-15(11-17)20(23,19(25)26)9-1-2-10-21(27)28/h3-6,15,17-18,27-28H,1-2,7-13,23H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439247 (CHEMBL2418831) Show SMILES NC(CCCCB(O)O)(C1CC2CCC(C1)N2Cc1ccc(Cl)c(Cl)c1)C(O)=O Show InChI InChI=1/C20H29BCl2N2O4/c22-17-6-3-13(9-18(17)23)12-25-15-4-5-16(25)11-14(10-15)20(24,19(26)27)7-1-2-8-21(28)29/h3,6,9,14-16,28-29H,1-2,4-5,7-8,10-12,24H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439245 (CHEMBL2418991) Show SMILES NC(CCCCB(O)O)(C1CC2CCC(C1)N2Cc1ccc(F)c(F)c1)C(O)=O Show InChI InChI=1/C20H29BF2N2O4/c22-17-6-3-13(9-18(17)23)12-25-15-4-5-16(25)11-14(10-15)20(24,19(26)27)7-1-2-8-21(28)29/h3,6,9,14-16,28-29H,1-2,4-5,7-8,10-12,24H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439244 (CHEMBL2418829) Show SMILES NC(CCCCB(O)O)(C1CC2CCC(C1)N2Cc1ccccc1)C(O)=O Show InChI InChI=1/C20H31BN2O4/c22-20(19(24)25,10-4-5-11-21(26)27)16-12-17-8-9-18(13-16)23(17)14-15-6-2-1-3-7-15/h1-3,6-7,16-18,26-27H,4-5,8-14,22H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427899 (CHEMBL2326090) Show SMILES CN[C@](CCCCB(O)O)(CCN1CCCCC1)C(O)=O Show InChI InChI=1/C14H29BN2O4/c1-16-14(13(18)19,7-3-4-9-15(20)21)8-12-17-10-5-2-6-11-17/h16,20-21H,2-12H2,1H3,(H,18,19)/t14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439242 (CHEMBL2418828) Show SMILES NC(CCCCB(O)O)(C1CC2CCC(C1)N2)C(O)=O Show InChI InChI=1/C13H25BN2O4/c15-13(12(17)18,5-1-2-6-14(19)20)9-7-10-3-4-11(8-9)16-10/h9-11,16,19-20H,1-8,15H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439243 (CHEMBL2418998) Show SMILES NC(CCCCB(O)O)(C1CCN(CCCc2ccc(Cl)cc2Cl)CC1)C(O)=O Show InChI InChI=1/C20H31BCl2N2O4/c22-17-6-5-15(18(23)14-17)4-3-11-25-12-7-16(8-13-25)20(24,19(26)27)9-1-2-10-21(28)29/h5-6,14,16,28-29H,1-4,7-13,24H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427903 (CHEMBL2326087) Show SMILES CC(C)NCC[C@](N)(CCCCB(O)O)C(O)=O Show InChI InChI=1/C11H25BN2O4/c1-9(2)14-8-6-11(13,10(15)16)5-3-4-7-12(17)18/h9,14,17-18H,3-8,13H2,1-2H3,(H,15,16)/t11-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439241 (CHEMBL2418999) Show SMILES NC(CCCCB(O)O)(C1CCN(CCCc2ccc(cc2)C(F)(F)F)CC1)C(O)=O Show InChI InChI=1/C21H32BF3N2O4/c23-21(24,25)18-7-5-16(6-8-18)4-3-13-27-14-9-17(10-15-27)20(26,19(28)29)11-1-2-12-22(30)31/h5-8,17,30-31H,1-4,9-15,26H2,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427904 (CHEMBL2326086) Show SMILES CCCN(C)CC[C@](N)(CCCCB(O)O)C(O)=O Show InChI InChI=1/C12H27BN2O4/c1-3-9-15(2)10-7-12(14,11(16)17)6-4-5-8-13(18)19/h18-19H,3-10,14H2,1-2H3,(H,16,17)/t12-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427911 (CHEMBL2326095) Show SMILES N[C@](CCCCB(O)O)(CCN1CCCC1)C(O)=O Show InChI InChI=1/C12H25BN2O4/c14-12(11(16)17,5-1-2-7-13(18)19)6-10-15-8-3-4-9-15/h18-19H,1-10,14H2,(H,16,17)/t12-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439240 (CHEMBL2418993) Show SMILES CC(C)CCN1CCC(CC1)C(N)(CCCCB(O)O)C(O)=O Show InChI InChI=1/C16H33BN2O4/c1-13(2)5-10-19-11-6-14(7-12-19)16(18,15(20)21)8-3-4-9-17(22)23/h13-14,22-23H,3-12,18H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439238 (CHEMBL2418995) Show SMILES NC(CCCCB(O)O)(C1CCN(Cc2ccc(Cl)cc2)CC1)C(O)=O Show InChI InChI=1/C18H28BClN2O4/c20-16-5-3-14(4-6-16)13-22-11-7-15(8-12-22)18(21,17(23)24)9-1-2-10-19(25)26/h3-6,15,25-26H,1-2,7-13,21H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439239 (CHEMBL2418994) Show SMILES NC(CCCCB(O)O)(C1CCN(Cc2ccccc2)CC1)C(O)=O Show InChI InChI=1/C18H29BN2O4/c20-18(17(22)23,10-4-5-11-19(24)25)16-8-12-21(13-9-16)14-15-6-2-1-3-7-15/h1-3,6-7,16,24-25H,4-5,8-14,20H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439237 (CHEMBL2418996) Show SMILES NC(CCCCB(O)O)(C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)C(O)=O Show InChI InChI=1/C18H27BCl2N2O4/c20-15-4-3-13(11-16(15)21)12-23-9-5-14(6-10-23)18(22,17(24)25)7-1-2-8-19(26)27/h3-4,11,14,26-27H,1-2,5-10,12,22H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427909 (CHEMBL2326097) Show SMILES COC[C@@H]1CCCN1CC[C@](N)(CCCCB(O)O)C(O)=O Show InChI InChI=1/C14H29BN2O5/c1-22-11-12-5-4-9-17(12)10-7-14(16,13(18)19)6-2-3-8-15(20)21/h12,20-21H,2-11,16H2,1H3,(H,18,19)/t12-,14+/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50439236 (CHEMBL2418997) Show SMILES NC(CCCCB(O)O)(C1CCN(CCc2ccc(Cl)cc2Cl)CC1)C(O)=O Show InChI InChI=1/C19H29BCl2N2O4/c21-16-4-3-14(17(22)13-16)5-10-24-11-6-15(7-12-24)19(23,18(25)26)8-1-2-9-20(27)28/h3-4,13,15,27-28H,1-2,5-12,23H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assay				Bioorg Med Chem Lett 23: 4837-41 (2013) Article DOI: 10.1016/j.bmcl.2013.06.092 BindingDB Entry DOI: 10.7270/Q2Z89DT6
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427900 ((R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]he...) Show SMILES N[C@](CCCCB(O)O)(CCN1CCCCC1)C(O)=O Show InChI InChI=1/C13H27BN2O4/c15-13(12(17)18,6-2-3-8-14(19)20)7-11-16-9-4-1-5-10-16/h19-20H,1-11,15H2,(H,17,18)/t13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50427913 (CHEMBL2326093) Show SMILES N[C@](CCCCB(O)O)(CCN1CCC(O)CC1)C(O)=O Show InChI InChI=1/C13H27BN2O5/c15-13(12(18)19,5-1-2-7-14(20)21)6-10-16-8-3-11(17)4-9-16/h11,17,20-21H,1-10,15H2,(H,18,19)/t13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...				J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290419 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((7-(trifluor...) Show SMILES N[C@]1(CN(CC2Cc3ccc(cc3CN2)C(F)(F)F)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C19H27BF3N3O4/c21-19(22,23)14-4-3-12-7-16(25-8-13(12)6-14)10-26-9-15(2-1-5-20(29)30)18(24,11-26)17(27)28/h3-4,6,15-16,25,29-30H,1-2,5,7-11,24H2,(H,27,28)/t15-,16?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290420 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(7-chloro-1,2...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccc(Cl)cc2CN1)C(O)=O Show InChI InChI=1/C18H25BClN3O5/c20-14-4-3-11-7-15(22-8-12(11)6-14)16(24)23-9-13(2-1-5-19(27)28)18(21,10-23)17(25)26/h3-4,6,13,15,22,27-28H,1-2,5,7-10,21H2,(H,25,26)/t13-,15?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290421 ((3R,4S)-3-amino-1-(2-amino-3-phenylpropyl)-4-(3- b...) Show SMILES NC(CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O)Cc1ccccc1 Show InChI InChI=1/C17H28BN3O4/c19-15(9-13-5-2-1-3-6-13)11-21-10-14(7-4-8-18(24)25)17(20,12-21)16(22)23/h1-3,5-6,14-15,24-25H,4,7-12,19-20H2,(H,22,23)/t14-,15?,17-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290423 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((5,7-dichlor...) Show SMILES N[C@]1(CN(CC2Cc3c(Cl)cc(Cl)cc3CN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C18H26BCl2N3O4/c20-13-4-11-7-23-14(6-15(11)16(21)5-13)9-24-8-12(2-1-3-19(27)28)18(22,10-24)17(25)26/h4-5,12,14,23,27-28H,1-3,6-10,22H2,(H,25,26)/t12-,14?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290426 ((1S,2S,4S)-1-amino-4-(benzylamino)-2-(3- boronopro...) Show SMILES N[C@]1(C[C@H](C[C@@H]1CCCB(O)O)NCc1ccccc1)C(O)=O Show InChI InChI=1/C16H25BN2O4/c18-16(15(20)21)10-14(9-13(16)7-4-8-17(22)23)19-11-12-5-2-1-3-6-12/h1-3,5-6,13-14,19,22-23H,4,7-11,18H2,(H,20,21)/t13-,14-,16-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290427 ((1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethyl...) Show SMILES CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C11H23BN2O4/c1-14(2)9-6-8(4-3-5-12(17)18)11(13,7-9)10(15)16/h8-9,17-18H,3-7,13H2,1-2H3,(H,15,16)/t8-,9-,11-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290428 ((1S,2S,4R)-1-amino-4-(aminomethyl)-2-(3- boronopro...) Show SMILES NC[C@@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C10H21BN2O4/c12-6-7-4-8(2-1-3-11(16)17)10(13,5-7)9(14)15/h7-8,16-17H,1-6,12-13H2,(H,14,15)/t7-,8+,10+/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290430 ((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...) Show SMILES NCC[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C11H23BN2O4/c13-5-3-8-6-9(2-1-4-12(17)18)11(14,7-8)10(15)16/h8-9,17-18H,1-7,13-14H2,(H,15,16)/t8-,9-,11-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290401 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyrrolidin-2...) Show SMILES N[C@]1(CN(CC2CCCN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C13H26BN3O4/c15-13(12(18)19)9-17(8-11-4-2-6-16-11)7-10(13)3-1-5-14(20)21/h10-11,16,20-21H,1-9,15H2,(H,18,19)/t10-,11?,13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290378 ((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...) Show SMILES NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C13H26BN3O4/c15-10-4-1-5-11(10)17-7-9(3-2-6-14(20)21)13(16,8-17)12(18)19/h9-11,20-21H,1-8,15-16H2,(H,18,19)/t9-,10?,11?,13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290402 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(pyrrolidi...) Show SMILES N[C@]1(CN(CCN2CCCC2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C14H28BN3O4/c16-14(13(19)20)11-18(9-8-17-6-1-2-7-17)10-12(14)4-3-5-15(21)22/h12,21-22H,1-11,16H2,(H,19,20)/t12-,14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290380 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(3-(4- carbox...) Show SMILES N[C@]1(CN(CCCc2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C17H27BN2O4/c19-17(16(21)22)13-20(12-15(17)9-4-10-18(23)24)11-5-8-14-6-2-1-3-7-14/h1-3,6-7,15,23-24H,4-5,8-13,19H2,(H,21,22)/t15-,17-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290382 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-3-...) Show SMILES N[C@]1(CN(CC2CCCNC2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C14H28BN3O4/c16-14(13(19)20)10-18(8-11-3-2-6-17-7-11)9-12(14)4-1-5-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11?,12-,14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290384 ((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...) Show SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C12H21BN4O4/c14-12(11(18)19)7-17(6-10-4-15-8-16-10)5-9(12)2-1-3-13(20)21/h4,8-9,20-21H,1-3,5-7,14H2,(H,15,16)(H,18,19)/t9-,12-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290388 ((3R,4S)-3-amino-1-(2-aminoethyl)-4-(3-boronopropyl...) Show SMILES NCCN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C10H22BN3O4/c12-4-5-14-6-8(2-1-3-11(17)18)10(13,7-14)9(15)16/h8,17-18H,1-7,12-13H2,(H,15,16)/t8-,10-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290391 ((3R,4S)-3-amino-4-(3-boronopropyl)-1,3'-bipyrrolid...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C1CCNC1)C(O)=O Show InChI InChI=1/C12H24BN3O4/c14-12(11(17)18)8-16(10-3-5-15-6-10)7-9(12)2-1-4-13(19)20/h9-10,15,19-20H,1-8,14H2,(H,17,18)/t9-,10?,12-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290392 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-3-...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C1CCCNC1)C(O)=O Show InChI InChI=1/C13H26BN3O4/c15-13(12(18)19)9-17(11-4-2-6-16-7-11)8-10(13)3-1-5-14(20)21/h10-11,16,20-21H,1-9,15H2,(H,18,19)/t10-,11?,13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290395 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methyl-1H...) Show SMILES Cn1ccnc1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C13H23BN4O4/c1-17-6-5-16-11(17)8-18-7-10(3-2-4-14(21)22)13(15,9-18)12(19)20/h5-6,10,21-22H,2-4,7-9,15H2,1H3,(H,19,20)/t10-,13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290397 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(piperidin...) Show SMILES N[C@]1(CN(CCN2CCCCC2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C15H30BN3O4/c17-15(14(20)21)12-19(10-9-18-7-2-1-3-8-18)11-13(15)5-4-6-16(22)23/h13,22-23H,1-12,17H2,(H,20,21)/t13-,15-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290398 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2- (diethyla...) Show SMILES CCN(CC)CCN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C14H30BN3O4/c1-3-17(4-2)8-9-18-10-12(6-5-7-15(21)22)14(16,11-18)13(19)20/h12,21-22H,3-11,16H2,1-2H3,(H,19,20)/t12-,14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290400 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...) Show SMILES CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C15H30BN3O4/c1-18-8-3-2-6-13(18)10-19-9-12(5-4-7-16(22)23)15(17,11-19)14(20)21/h12-13,22-23H,2-11,17H2,1H3,(H,20,21)/t12-,13?,15-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290403 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(((S)-1,2,3,4...) Show SMILES N[C@]1(CN(C[C@@H]2Cc3ccccc3CN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C18H28BN3O4/c20-18(17(23)24)12-22(10-15(18)6-3-7-19(25)26)11-16-8-13-4-1-2-5-14(13)9-21-16/h1-2,4-5,15-16,21,25-26H,3,6-12,20H2,(H,23,24)/t15-,16-,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290404 ((3R,4S)-3-amino-1-(2-(benzylamino)ethyl)-4-(3- bor...) Show SMILES N[C@]1(CN(CCNCc2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C17H28BN3O4/c19-17(16(22)23)13-21(12-15(17)7-4-8-18(24)25)10-9-20-11-14-5-2-1-3-6-14/h1-3,5-6,15,20,24-25H,4,7-13,19H2,(H,22,23)/t15-,17-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290405 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(3,4- dich...) Show SMILES N[C@]1(CN(CCNCc2ccc(Cl)c(Cl)c2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C17H26BCl2N3O4/c19-14-4-3-12(8-15(14)20)9-22-6-7-23-10-13(2-1-5-18(26)27)17(21,11-23)16(24)25/h3-4,8,13,22,26-27H,1-2,5-7,9-11,21H2,(H,24,25)/t13-,17-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O Show InChI InChI=1/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290416 ((3R,4S)-3-amino-1-(2-(biphenyl-4-ylamino)ethyl)-4-...) Show SMILES N[C@]1(CN(CCNc2ccc(cc2)-c2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C22H30BN3O4/c24-22(21(27)28)16-26(15-19(22)7-4-12-23(29)30)14-13-25-20-10-8-18(9-11-20)17-5-2-1-3-6-17/h1-3,5-6,8-11,19,25,29-30H,4,7,12-16,24H2,(H,27,28)/t19-,22-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290415 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((6-chloro-1,...) Show SMILES N[C@]1(CN(CC2Cc3cc(Cl)ccc3CN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C18H27BClN3O4/c20-15-4-3-12-8-22-16(7-13(12)6-15)10-23-9-14(2-1-5-19(26)27)18(21,11-23)17(24)25/h3-4,6,14,16,22,26-27H,1-2,5,7-11,21H2,(H,24,25)/t14-,16?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290413 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((7-chloro-1,...) Show SMILES N[C@]1(CN(CC2Cc3ccc(Cl)cc3CN2)C[C@@H]1CCCB(O)O)C(O)=O Show InChI InChI=1/C18H27BClN3O4/c20-15-4-3-12-7-16(22-8-13(12)6-15)10-23-9-14(2-1-5-19(26)27)18(21,11-23)17(24)25/h3-4,6,14,16,22,26-27H,1-2,5,7-11,21H2,(H,24,25)/t14-,16?,18-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290408 ((3R,4S)-3-amino-1-(2-aminocyclohexyl)-4-(3- borono...) Show SMILES NC1CCCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O Show InChI InChI=1/C14H28BN3O4/c16-11-5-1-2-6-12(11)18-8-10(4-3-7-15(21)22)14(17,9-18)13(19)20/h10-12,21-22H,1-9,16-17H2,(H,19,20)/t10-,11?,12?,14-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290407 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1CCCN1)C(O)=O Show InChI InChI=1/C13H24BN3O5/c15-13(12(19)20)8-17(11(18)10-4-2-6-16-10)7-9(13)3-1-5-14(21)22/h9-10,16,21-22H,1-8,15H2,(H,19,20)/t9-,10?,13-/s2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	Article US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) Article DOI: 10.1021/jm070104l BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair

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