BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arginyl-tRNA synthetase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginyl-tRNA synthetase


(Homo sapiens)
BDBM50091515
PNG
(Aminoalkyl adenylate and aminoacyl sulfamate analo...)
Show SMILES N[C@@H](CCCNC(N)=[NH2+])C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C16H26N10O7S/c17-7(2-1-3-21-16(19)20)14(29)25-34(30,31)32-4-8-10(27)11(28)15(33-8)26-6-24-9-12(18)22-5-23-13(9)26/h5-8,10-11,15,27-28H,1-4,17H2,(H,25,29)(H2,18,22,23)(H4,19,20,21)/p+1/t7-,8+,10+,11+,15+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against cognate Staphylococcus aureus Arginyl-tRNA synthetase


Bioorg Med Chem Lett 10: 1871-4 (2000)

More data for this
Ligand-Target Pair
Arginyl-tRNA synthetase


(Homo sapiens)
BDBM50091518
PNG
(CHEMBL434782 | Phosphoric acid (S)-2-amino-5-guani...)
Show SMILES N[C@@H](CCCNC(N)=[NH2+])COP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C16H28N9O7P/c17-8(2-1-3-21-16(19)20)4-30-33(28,29)31-5-9-11(26)12(27)15(32-9)25-7-24-10-13(18)22-6-23-14(10)25/h6-9,11-12,15,26-27H,1-5,17H2,(H,28,29)(H2,18,22,23)(H4,19,20,21)/t8-,9+,11+,12+,15+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7.5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against cognate Staphylococcus aureus Arginyl-tRNA synthetase


Bioorg Med Chem Lett 10: 1871-4 (2000)

More data for this
Ligand-Target Pair