BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 13 hits Enz. Inhib. hit(s) with Target = 'Asialoglycoprotein receptor 1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304486
PNG
((3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahy...)
Show SMILES CC(=O)N[C@H]1C(OC(C)=O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O
Show InChI InChI=1S/C16H23NO10/c1-7(18)17-13-15(25-10(4)21)14(24-9(3)20)12(6-23-8(2)19)27-16(13)26-11(5)22/h12-16H,6H2,1-5H3,(H,17,18)/t12-,13-,14+,15-,16?/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.13E+5n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50077229
PNG
(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
Show SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.05E+6n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304487
PNG
((2R,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Show SMILES COC[C@H]1O[C@@H](OC)[C@H](OC)[C@@H](OC)[C@H]1OC
Show InChI InChI=1S/C11H22O6/c1-12-6-7-8(13-2)9(14-3)10(15-4)11(16-5)17-7/h7-11H,6H2,1-5H3/t7-,8+,9+,10-,11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.83E+6n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304488
PNG
((2S,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Show SMILES COC[C@H]1O[C@H](OC)[C@H](OC)[C@@H](OC)[C@H]1OC
Show InChI InChI=1S/C11H22O6/c1-12-6-7-8(13-2)9(14-3)10(15-4)11(16-5)17-7/h7-11H,6H2,1-5H3/t7-,8+,9+,10-,11+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.83E+6n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50240803
PNG
(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Show SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a>3.00E+7n/an/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Mus musculus)
BDBM50074090
PNG
(CHEMBL2368210 | Galactoside analogue)
Show SMILES OC[C@@H]1O[C@@H](OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)NC(=O)CNC(=O)OCc2ccccc2)[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C65H110N8O30/c74-34-42-52(84)55(87)58(90)61(101-42)97-27-7-4-15-45(77)66-21-10-24-69-48(80)18-30-94-38-65(73-51(83)33-72-64(93)100-37-41-13-2-1-3-14-41,39-95-31-19-49(81)70-25-11-22-67-46(78)16-5-8-28-98-62-59(91)56(88)53(85)43(35-75)102-62)40-96-32-20-50(82)71-26-12-23-68-47(79)17-6-9-29-99-63-60(92)57(89)54(86)44(36-76)103-63/h1-3,13-14,42-44,52-63,74-76,84-92H,4-12,15-40H2,(H,66,77)(H,67,78)(H,68,79)(H,69,80)(H,70,81)(H,71,82)(H,72,93)(H,73,83)/t42?,43?,44?,52-,53-,54-,55?,56?,57?,58?,59?,60?,61?,62?,63?,65?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
93n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells


J Med Chem 42: 609-18 (1999)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Mus musculus)
BDBM50074091
PNG
(CHEMBL2368208 | Galactoside analogue)
Show SMILES OC[C@@H]1O[C@@H](OCCCCC(=O)NCC(=O)NCCCC(=O)OCC(COC(=O)CCCNC(=O)CNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)(COC(=O)CCCNC(=O)CNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)NC(=O)CNC(=O)OCc2ccccc2)[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C65H104N8O33/c74-31-39-52(87)55(90)58(93)61(104-39)97-24-7-4-15-42(77)69-27-45(80)66-21-10-18-49(84)101-35-65(73-48(83)30-72-64(96)100-34-38-13-2-1-3-14-38,36-102-50(85)19-11-22-67-46(81)28-70-43(78)16-5-8-25-98-62-59(94)56(91)53(88)40(32-75)105-62)37-103-51(86)20-12-23-68-47(82)29-71-44(79)17-6-9-26-99-63-60(95)57(92)54(89)41(33-76)106-63/h1-3,13-14,39-41,52-63,74-76,87-95H,4-12,15-37H2,(H,66,80)(H,67,81)(H,68,82)(H,69,77)(H,70,78)(H,71,79)(H,72,96)(H,73,83)/t39?,40?,41?,52-,53-,54-,55?,56?,57?,58?,59?,60?,61?,62?,63?,65?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
93n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells


J Med Chem 42: 609-18 (1999)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Mus musculus)
BDBM50074089
PNG
(CHEMBL2368207 | TG(20)C-Galactoside analogue)
Show SMILES CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CNC(=O)CCCCC(=O)NCC(=O)NC(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C86H153N3O38/c1-57(2)9-8-10-58(3)62-15-16-63-61-14-13-59-45-60(17-19-84(59,4)64(61)18-20-85(62,63)5)124-71(96)47-88-69(94)12-7-6-11-68(93)87-46-70(95)89-86(51-118-54-115-36-33-109-24-21-106-27-30-112-39-42-121-81-78(103)75(100)72(97)65(48-90)125-81,52-119-55-116-37-34-110-25-22-107-28-31-113-40-43-122-82-79(104)76(101)73(98)66(49-91)126-82)53-120-56-117-38-35-111-26-23-108-29-32-114-41-44-123-83-80(105)77(102)74(99)67(50-92)127-83/h13,57-58,60-67,72-83,90-92,97-105H,6-12,14-56H2,1-5H3,(H,87,93)(H,88,94)(H,89,95)/t58?,60-,61?,62+,63?,64?,65?,66?,67?,72+,73+,74+,75?,76?,77?,78?,79?,80?,81?,82?,83?,84-,85+,86?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
200n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells


J Med Chem 42: 609-18 (1999)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50240803
PNG
(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Show SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a>1.00E+7n/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304488
PNG
((2S,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Show SMILES COC[C@H]1O[C@H](OC)[C@H](OC)[C@@H](OC)[C@H]1OC
Show InChI InChI=1S/C11H22O6/c1-12-6-7-8(13-2)9(14-3)10(15-4)11(16-5)17-7/h7-11H,6H2,1-5H3/t7-,8+,9+,10-,11+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 2.76E+6n/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50077229
PNG
(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
Show SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a 1.46E+6n/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304486
PNG
((3R,4R,5R,6R)-3-acetamido-6-(acetoxymethyl)tetrahy...)
Show SMILES CC(=O)N[C@H]1C(OC(C)=O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O
Show InChI InChI=1S/C16H23NO10/c1-7(18)17-13-15(25-10(4)21)14(24-9(3)20)12(6-23-8(2)19)27-16(13)26-11(5)22/h12-16H,6H2,1-5H3,(H,17,18)/t12-,13-,14+,15-,16?/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/a 1.50E+5n/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair
Asialoglycoprotein receptor 1


(Homo sapiens)
BDBM50304487
PNG
((2R,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxyme...)
Show SMILES COC[C@H]1O[C@@H](OC)[C@H](OC)[C@@H](OC)[C@H]1OC
Show InChI InChI=1S/C11H22O6/c1-12-6-7-8(13-2)9(14-3)10(15-4)11(16-5)17-7/h7-11H,6H2,1-5H3/t7-,8+,9+,10-,11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 2.20E+6n/an/an/an/an/a



University of Basel

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...


Bioorg Med Chem 17: 7254-64 (2009)

More data for this
Ligand-Target Pair