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Found 5 hits Enz. Inhib. hit(s) with Target = 'Autoinducer 1 sensor kinase/phosphatase luxN'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Autoinducer 1 sensor kinase/phosphatase luxN


(Vibrio harveyi)
BDBM50351500
PNG
(CHEMBL1823949)
Show SMILES CC(C)(c1ccccc1)c1ccc(OCC(=O)NC2CCCC2)cc1
Show InChI InChI=1S/C22H27NO2/c1-22(2,17-8-4-3-5-9-17)18-12-14-20(15-13-18)25-16-21(24)23-19-10-6-7-11-19/h3-5,8-9,12-15,19H,6-7,10-11,16H2,1-2H3,(H,23,24)
UniProtKB/SwissProt

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PC sid
UniChem
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Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi


Citation and Details
More data for this
Ligand-Target Pair
Autoinducer 1 sensor kinase/phosphatase luxN


(Vibrio harveyi)
BDBM50351501
PNG
(CHEMBL1823948)
Show SMILES Clc1ccc(cc1)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H12Cl2O3S/c20-15-5-1-13(2-6-15)19(22)14-3-9-17(10-4-14)25(23,24)18-11-7-16(21)8-12-18/h1-12H
UniProtKB/SwissProt

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PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi


Citation and Details
More data for this
Ligand-Target Pair
Autoinducer 1 sensor kinase/phosphatase luxN


(Vibrio harveyi)
BDBM50351503
PNG
(CHEMBL1823946)
Show SMILES CC(C)CC(NS(=O)(=O)c1ccc2CCN(C(C)=O)c2c1)C(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C23H28ClN3O4S/c1-15(2)12-21(23(29)25-14-17-4-7-19(24)8-5-17)26-32(30,31)20-9-6-18-10-11-27(16(3)28)22(18)13-20/h4-9,13,15,21,26H,10-12,14H2,1-3H3,(H,25,29)
UniProtKB/SwissProt

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PC sid
UniChem
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Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi


Citation and Details
More data for this
Ligand-Target Pair
Autoinducer 1 sensor kinase/phosphatase luxN


(Vibrio harveyi)
BDBM50351502
PNG
(CHEMBL1823947)
Show SMILES COc1ccc(CNC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1
Show InChI InChI=1S/C21H25N3O4S2/c1-13(2)20(21(25)22-12-15-5-7-16(28-4)8-6-15)24-30(26,27)17-9-10-18-19(11-17)29-14(3)23-18/h5-11,13,20,24H,12H2,1-4H3,(H,22,25)
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Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi


Citation and Details
More data for this
Ligand-Target Pair
Autoinducer 1 sensor kinase/phosphatase luxN


(Vibrio harveyi)
BDBM50351499
PNG
(CHEMBL1823950)
Show SMILES CC(C)OC(=O)CSc1nc2ccccc2[nH]1
Show InChI InChI=1S/C12H14N2O2S/c1-8(2)16-11(15)7-17-12-13-9-5-3-4-6-10(9)14-12/h3-6,8H,7H2,1-2H3,(H,13,14)
UniProtKB/SwissProt

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CHEMBL
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UniChem

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Article
PubMed
n/an/a 6.23E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi


Citation and Details
More data for this
Ligand-Target Pair