BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'Beta-ketoacyl-ACP-synthase III'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245829
PNG
(2-(methylsulfonyl)naphthalene-1,4-diol | CHEMBL491...)
Show SMILES CS(=O)(=O)c1cc(O)c2ccccc2c1O
Show InChI InChI=1S/C11H10O4S/c1-16(14,15)10-6-9(12)7-4-2-3-5-8(7)11(10)13/h2-6,12-13H,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 27.4n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245878
PNG
(CHEMBL512926 | N-(4-(1,4-dihydroxynaphthalen-2-yls...)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)c1cc(O)c2ccccc2c1O
Show InChI InChI=1S/C18H15NO5S/c1-11(20)19-12-6-8-13(9-7-12)25(23,24)17-10-16(21)14-4-2-3-5-15(14)18(17)22/h2-10,21-22H,1H3,(H,19,20)
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 29.6n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245830
PNG
(3-(1,4-dihydroxynaphthalen-2-ylsulfonyl)propanoic ...)
Show SMILES OC(=O)CCS(=O)(=O)c1cc(O)c2ccccc2c1O
Show InChI InChI=1S/C13H12O6S/c14-10-7-11(20(18,19)6-5-12(15)16)13(17)9-4-2-1-3-8(9)10/h1-4,7,14,17H,5-6H2,(H,15,16)
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 46.5n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245880
PNG
(2-(4-propylphenylsulfonyl)naphthalene-1,4-diol | C...)
Show SMILES CCCc1ccc(cc1)S(=O)(=O)c1cc(O)c2ccccc2c1O
Show InChI InChI=1S/C19H18O4S/c1-2-5-13-8-10-14(11-9-13)24(22,23)18-12-17(20)15-6-3-4-7-16(15)19(18)21/h3-4,6-12,20-21H,2,5H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 72.6n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245828
PNG
(2-Tosylnaphthalene-1,4-diol | CHEMBL509952)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1cc(O)c2ccccc2c1O
Show InChI InChI=1S/C17H14O4S/c1-11-6-8-12(9-7-11)22(20,21)16-10-15(18)13-4-2-3-5-14(13)17(16)19/h2-10,18-19H,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 73.6n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245879
PNG
(2-(4-chlorophenylsulfonyl)naphthalene-1,4-diol | C...)
Show SMILES Oc1cc(c(O)c2ccccc12)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C16H11ClO4S/c17-10-5-7-11(8-6-10)22(20,21)15-9-14(18)12-3-1-2-4-13(12)16(15)19/h1-9,18-19H
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 129n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245877
PNG
(2-(phenylsulfonyl)naphthalene-1,4-diol | CHEMBL462...)
Show SMILES Oc1cc(c(O)c2ccccc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C16H12O4S/c17-14-10-15(16(18)13-9-5-4-8-12(13)14)21(19,20)11-6-2-1-3-7-11/h1-10,17-18H
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 279n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245924
PNG
(2-tosylanthracene-1,4-diol | CHEMBL451059)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1cc(O)c2cc3ccccc3cc2c1O
Show InChI InChI=1S/C21H16O4S/c1-13-6-8-16(9-7-13)26(24,25)20-12-19(22)17-10-14-4-2-3-5-15(14)11-18(17)21(20)23/h2-12,22-23H,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 341n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245923
PNG
(2-(naphthalen-2-ylsulfonyl)naphthalene-1,4-diol | ...)
Show SMILES Oc1cc(c(O)c2ccccc12)S(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C20H14O4S/c21-18-12-19(20(22)17-8-4-3-7-16(17)18)25(23,24)15-10-9-13-5-1-2-6-14(13)11-15/h1-12,21-22H
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 393n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair
Beta-ketoacyl-ACP-synthase III


(Plasmodium falciparum)
BDBM50245928
PNG
(2-tosylnaphthalene-1,4-dione | CHEMBL454282)
Show SMILES Cc1ccc(cc1)S(=O)(=O)C1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C17H12O4S/c1-11-6-8-12(9-7-11)22(20,21)16-10-15(18)13-4-2-3-5-14(13)17(16)19/h2-10H,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.43E+3n/an/an/an/an/an/a



Portland State University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FabH


Citation and Details
More data for this
Ligand-Target Pair