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Compile Data Set for Download or QSAR

Found 78 hits Enz. Inhib. hit(s) with Target = 'Beta-lactamase L1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092976
PNG
(CHEMBL3586478)
Show SMILES CSCC[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C13H17NO4S3/c1-19-6-4-10(13(18)21-8-12(16)17)14-11(15)7-9-3-2-5-20-9/h2-3,5,10H,4,6-8H2,1H3,(H,14,15)(H,16,17)/t10-/s2
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n/an/a 18n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092979
PNG
(CHEMBL3586477)
Show SMILES CC(C)C[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C14H19NO4S2/c1-9(2)6-11(14(19)21-8-13(17)18)15-12(16)7-10-4-3-5-20-10/h3-5,9,11H,6-8H2,1-2H3,(H,15,16)(H,17,18)/t11-/s2
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n/an/a 69n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092982
PNG
(CHEMBL3585360)
Show SMILES OC(=O)CSC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1cccs1
Show InChI InChI=1/C19H18N2O4S2/c22-17(9-13-4-3-7-26-13)21-16(19(25)27-11-18(23)24)8-12-10-20-15-6-2-1-5-14(12)15/h1-7,10,16,20H,8-9,11H2,(H,21,22)(H,23,24)/t16-/s2
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n/an/a 290n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50093027
PNG
(CHEMBL3586482)
Show SMILES OC(=O)CSC(=O)[C@@H]1CCCN1C(=O)Cc1cccs1
Show InChI InChI=1S/C35H46N4O9/c1-5-21(4)30(36-27(40)13-14-28(41)42)32(44)37-29(20(2)3)33(45)39-18-24(17-26(39)31(43)38-35(15-16-35)34(46)47)48-19-23-11-8-10-22-9-6-7-12-25(22)23/h6-12,20-21,24,26,29-30H,5,13-19H2,1-4H3,(H,36,40)(H,37,44)(H,38,43)(H,41,42)(H,46,47)/t21?,24-,26+,29+,30+/m1/s1
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n/an/a 450n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092842
PNG
(CHEMBL3586476)
Show SMILES CC(C)[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1S/C16H18N2O2.C4H4O4/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14;5-3(6)1-2-4(7)8/h5-8,10-12H,1-4,9H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
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n/an/a 450n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092977
PNG
(CHEMBL3586474)
Show SMILES OC(=O)CSC(=O)CNC(=O)Cc1cccs1
Show InChI InChI=1S/C10H11NO4S2/c12-8(4-7-2-1-3-16-7)11-5-10(15)17-6-9(13)14/h1-3H,4-6H2,(H,11,12)(H,13,14)
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n/an/a 840n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092978
PNG
(CHEMBL3586475)
Show SMILES C[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C11H13NO4S2/c1-7(11(16)18-6-10(14)15)12-9(13)5-8-3-2-4-17-8/h2-4,7H,5-6H2,1H3,(H,12,13)(H,14,15)/t7-/s2
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n/an/a 910n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50008093
PNG
(CHEMBL3234717)
Show SMILES COC(=O)C(CSc1cc(C(=O)OC)c2nc3cccc(C(O)=O)c3nc2c1)NC(C)=O
Show InChI InChI=1S/C21H19N3O7S/c1-10(25)22-16(21(29)31-3)9-32-11-7-13(20(28)30-2)18-15(8-11)24-17-12(19(26)27)5-4-6-14(17)23-18/h4-8,16H,9H2,1-3H3,(H,22,25)(H,26,27)
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n/an/a 1.00E+3n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia metallo-beta-lactamase L1 after 5 mins


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50008090
PNG
(CHEMBL3234716)
Show SMILES COC(=O)c1c(O)ccc2nc3c(cccc3nc12)C(O)=O
Show InChI InChI=1S/C15H10N2O5/c1-22-15(21)11-10(18)6-5-9-13(11)17-8-4-2-3-7(14(19)20)12(8)16-9/h2-6,18H,1H3,(H,19,20)
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n/an/a 1.00E+3n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia metallo-beta-lactamase L1 after 5 mins


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092997
PNG
(CHEMBL3586481)
Show SMILES OC(=O)CSC(=O)[C@H](CCCCNC(=O)Cc1cccs1)NC(=O)Cc1cccs1
Show InChI InChI=1/C20H24N2O5S3/c23-17(11-14-5-3-9-28-14)21-8-2-1-7-16(20(27)30-13-19(25)26)22-18(24)12-15-6-4-10-29-15/h3-6,9-10,16H,1-2,7-8,11-13H2,(H,21,23)(H,22,24)(H,25,26)/t16-/s2
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n/an/a 1.08E+3n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092980
PNG
(CHEMBL3586479)
Show SMILES OC[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C11H13NO5S2/c13-5-8(11(17)19-6-10(15)16)12-9(14)4-7-2-1-3-18-7/h1-3,8,13H,4-6H2,(H,12,14)(H,15,16)/t8-/s2
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n/an/a 1.49E+3n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092981
PNG
(CHEMBL3586480)
Show SMILES OC(=O)CSC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1cccs1
Show InChI InChI=1/C17H17NO4S2/c19-15(10-13-7-4-8-23-13)18-14(17(22)24-11-16(20)21)9-12-5-2-1-3-6-12/h1-8,14H,9-11H2,(H,18,19)(H,20,21)/t14-/s2
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n/an/a 2.90E+3n/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50076680
PNG
(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Show SMILES C[C@]1(\C=C\C#N)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
Show InChI InChI=1S/C10H10N2O5S/c1-10(3-2-4-11)8(9(14)15)12-6(13)5-7(12)18(10,16)17/h2-3,7-8H,5H2,1H3,(H,14,15)/p-1/b3-2+/t7-,8+,10+/m1/s1
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n/an/a 2.40E+4n/an/an/an/an/an/a



F. Hoffmann-LaRoche Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of Beta-lactamase from Xanthomonas maltophila 328


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50053173
PNG
((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Show SMILES C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O
Show InChI InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
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n/an/a 4.00E+6n/an/an/an/an/an/a



F. Hoffmann-LaRoche Ltd

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of Beta-lactamase from Xanthomonas maltophila 328


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191983
PNG
(3-((1-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C21H23N3O6S/c22-18(26)17(8-12-4-2-1-3-5-12)24-20(28)16(6-7-31)23-19(27)13-9-14(21(29)30)11-15(25)10-13/h1-5,9-11,16-17,25,31H,6-8H2,(H2,22,26)(H,23,27)(H,24,28)(H,29,30)/t16?,17-/m1/s1
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2.10n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191983
PNG
(3-((1-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C21H23N3O6S/c22-18(26)17(8-12-4-2-1-3-5-12)24-20(28)16(6-7-31)23-19(27)13-9-14(21(29)30)11-15(25)10-13/h1-5,9-11,16-17,25,31H,6-8H2,(H2,22,26)(H,23,27)(H,24,28)(H,29,30)/t16?,17-/m1/s1
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5.80n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191986
PNG
((2R)-2-(2-(5-fluoro-1H-indole-2-carboxamido)-4-mer...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cc(F)ccc2[nH]1
Show InChI InChI=1S/C22H22FN3O4S/c23-15-6-7-16-14(11-15)12-18(24-16)21(28)25-17(8-9-31)20(27)26-19(22(29)30)10-13-4-2-1-3-5-13/h1-7,11-12,17,19,24,31H,8-10H2,(H,25,28)(H,26,27)(H,29,30)/t17?,19-/m1/s1
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12n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191987
PNG
(6-((1-((R)-1-carboxy-2-phenylethylamino)-4-mercapt...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cccc(n1)C(O)=O
Show InChI InChI=1S/C20H21N3O6S/c24-17(13-7-4-8-15(21-13)19(26)27)22-14(9-10-30)18(25)23-16(20(28)29)11-12-5-2-1-3-6-12/h1-8,14,16,30H,9-11H2,(H,22,24)(H,23,25)(H,26,27)(H,28,29)/t14?,16-/m1/s1
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12n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191996
PNG
(6-((1-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cccc(n1)C(O)=O
Show InChI InChI=1S/C20H22N4O5S/c21-17(25)16(11-12-5-2-1-3-6-12)24-19(27)14(9-10-30)23-18(26)13-7-4-8-15(22-13)20(28)29/h1-8,14,16,30H,9-11H2,(H2,21,25)(H,23,26)(H,24,27)(H,28,29)/t14?,16-/m1/s1
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26n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092976
PNG
(CHEMBL3586478)
Show SMILES CSCC[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C13H17NO4S3/c1-19-6-4-10(13(18)21-8-12(16)17)14-11(15)7-9-3-2-5-20-9/h2-3,5,10H,4,6-8H2,1H3,(H,14,15)(H,16,17)/t10-/s2
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110n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191987
PNG
(6-((1-((R)-1-carboxy-2-phenylethylamino)-4-mercapt...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cccc(n1)C(O)=O
Show InChI InChI=1S/C20H21N3O6S/c24-17(13-7-4-8-15(21-13)19(26)27)22-14(9-10-30)18(25)23-16(20(28)29)11-12-5-2-1-3-6-12/h1-8,14,16,30H,9-11H2,(H,22,24)(H,23,25)(H,26,27)(H,28,29)/t14?,16-/m1/s1
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120n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191983
PNG
(3-((1-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)...)
Show SMILES NC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C21H23N3O6S/c22-18(26)17(8-12-4-2-1-3-5-12)24-20(28)16(6-7-31)23-19(27)13-9-14(21(29)30)11-15(25)10-13/h1-5,9-11,16-17,25,31H,6-8H2,(H2,22,26)(H,23,27)(H,24,28)(H,29,30)/t16?,17-/m1/s1
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130n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50192000
PNG
(3-((1-((R)-1-carboxy-2-phenylethylamino)-4-mercapt...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C21H22N2O7S/c24-15-10-13(9-14(11-15)20(27)28)18(25)22-16(6-7-31)19(26)23-17(21(29)30)8-12-4-2-1-3-5-12/h1-5,9-11,16-17,24,31H,6-8H2,(H,22,25)(H,23,26)(H,27,28)(H,29,30)/t16?,17-/m1/s1
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140n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191991
PNG
((2R)-2-(4-mercapto-2-(7-nitro-1H-indole-2-carboxam...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1
Show InChI InChI=1S/C22H22N4O6S/c27-20(25-17(22(29)30)11-13-5-2-1-3-6-13)15(9-10-33)24-21(28)16-12-14-7-4-8-18(26(31)32)19(14)23-16/h1-8,12,15,17,23,33H,9-11H2,(H,24,28)(H,25,27)(H,29,30)/t15?,17-/m1/s1
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150n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191982
PNG
((2R)-2-(4-mercapto-2-(2-(2-nitrophenyl)furan-5-car...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1ccc(o1)-c1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C24H23N3O7S/c28-22(26-18(24(30)31)14-15-6-2-1-3-7-15)17(12-13-35)25-23(29)21-11-10-20(34-21)16-8-4-5-9-19(16)27(32)33/h1-11,17-18,35H,12-14H2,(H,25,29)(H,26,28)(H,30,31)/t17?,18-/m1/s1
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160n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092980
PNG
(CHEMBL3586479)
Show SMILES OC[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C11H13NO5S2/c13-5-8(11(17)19-6-10(15)16)12-9(14)4-7-2-1-3-18-7/h1-3,8,13H,4-6H2,(H,12,14)(H,15,16)/t8-/s2
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170n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092982
PNG
(CHEMBL3585360)
Show SMILES OC(=O)CSC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1cccs1
Show InChI InChI=1/C19H18N2O4S2/c22-17(9-13-4-3-7-26-13)21-16(19(25)27-11-18(23)24)8-12-10-20-15-6-2-1-5-14(12)15/h1-7,10,16,20H,8-9,11H2,(H,21,22)(H,23,24)/t16-/s2
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170n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092997
PNG
(CHEMBL3586481)
Show SMILES OC(=O)CSC(=O)[C@H](CCCCNC(=O)Cc1cccs1)NC(=O)Cc1cccs1
Show InChI InChI=1/C20H24N2O5S3/c23-17(11-14-5-3-9-28-14)21-8-2-1-7-16(20(27)30-13-19(25)26)22-18(24)12-15-6-4-10-29-15/h3-6,9-10,16H,1-2,7-8,11-13H2,(H,21,23)(H,22,24)(H,25,26)/t16-/s2
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190n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191992
PNG
((2R)-2-(2-(5-chloro-1H-indole-2-carboxamido)-4-mer...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H22ClN3O4S/c23-15-6-7-16-14(11-15)12-18(24-16)21(28)25-17(8-9-31)20(27)26-19(22(29)30)10-13-4-2-1-3-5-13/h1-7,11-12,17,19,24,31H,8-10H2,(H,25,28)(H,26,27)(H,29,30)/t17?,19-/m1/s1
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200n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50192002
PNG
((2R)-2-(2-(4-(benzyloxy)-3,5-dimethylbenzamido)-4-...)
Show SMILES Cc1cc(cc(C)c1OCc1ccccc1)C(=O)NC(CCS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H32N2O5S/c1-19-15-23(16-20(2)26(19)36-18-22-11-7-4-8-12-22)27(32)30-24(13-14-37)28(33)31-25(29(34)35)17-21-9-5-3-6-10-21/h3-12,15-16,24-25,37H,13-14,17-18H2,1-2H3,(H,30,32)(H,31,33)(H,34,35)/t24?,25-/m1/s1
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200n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092979
PNG
(CHEMBL3586477)
Show SMILES CC(C)C[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C14H19NO4S2/c1-9(2)6-11(14(19)21-8-13(17)18)15-12(16)7-10-4-3-5-20-10/h3-5,9,11H,6-8H2,1-2H3,(H,15,16)(H,17,18)/t11-/s2
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210n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191998
PNG
((2R)-2-(2-(3-butylpicolinamido)-4-mercaptobutanami...)
Show SMILES CCCCc1ccc(nc1)C(=O)NC(CCS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C23H29N3O4S/c1-2-3-7-17-10-11-18(24-15-17)21(27)25-19(12-13-31)22(28)26-20(23(29)30)14-16-8-5-4-6-9-16/h4-6,8-11,15,19-20,31H,2-3,7,12-14H2,1H3,(H,25,27)(H,26,28)(H,29,30)/t19?,20-/m1/s1
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230n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50192003
PNG
((2R)-2-(2-(3-chloro-2-hydroxynicotinamido)-4-merca...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1c[nH]c(=O)c(Cl)c1
Show InChI InChI=1S/C19H20ClN3O5S/c20-13-9-12(10-21-17(13)25)16(24)22-14(6-7-29)18(26)23-15(19(27)28)8-11-4-2-1-3-5-11/h1-5,9-10,14-15,29H,6-8H2,(H,21,25)(H,22,24)(H,23,26)(H,27,28)/t14?,15-/m1/s1
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260n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092842
PNG
(CHEMBL3586476)
Show SMILES CC(C)[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1S/C16H18N2O2.C4H4O4/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14;5-3(6)1-2-4(7)8/h5-8,10-12H,1-4,9H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
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280n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092977
PNG
(CHEMBL3586474)
Show SMILES OC(=O)CSC(=O)CNC(=O)Cc1cccs1
Show InChI InChI=1S/C10H11NO4S2/c12-8(4-7-2-1-3-16-7)11-5-10(15)17-6-9(13)14/h1-3H,4-6H2,(H,11,12)(H,13,14)
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280n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191989
PNG
((2R)-2-(4-mercapto-2-(2-(naphthalen-1-yloxy)acetam...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)COc1cccc2ccccc12
Show InChI InChI=1S/C25H26N2O5S/c28-23(16-32-22-12-6-10-18-9-4-5-11-19(18)22)26-20(13-14-33)24(29)27-21(25(30)31)15-17-7-2-1-3-8-17/h1-12,20-21,33H,13-16H2,(H,26,28)(H,27,29)(H,30,31)/t20?,21-/m1/s1
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290n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191997
PNG
((2R)-2-(2-(1H-indole-2-carboxamido)-4-mercaptobuta...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C22H23N3O4S/c26-20(25-19(22(28)29)12-14-6-2-1-3-7-14)17(10-11-30)24-21(27)18-13-15-8-4-5-9-16(15)23-18/h1-9,13,17,19,23,30H,10-12H2,(H,24,27)(H,25,26)(H,28,29)/t17?,19-/m1/s1
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290n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191984
PNG
((2R)-2-(2-(2-(4-bromophenyl)acetamido)-4-mercaptob...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)Cc1ccc(Br)cc1
Show InChI InChI=1S/C21H23BrN2O4S/c22-16-8-6-15(7-9-16)13-19(25)23-17(10-11-29)20(26)24-18(21(27)28)12-14-4-2-1-3-5-14/h1-9,17-18,29H,10-13H2,(H,23,25)(H,24,26)(H,27,28)/t17?,18-/m1/s1
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350n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50192001
PNG
((2R)-2-(2-(2-(4-acetamido-3-nitrophenyl)acetamido)...)
Show SMILES CC(=O)Nc1ccc(CC(=O)NC(CCS)C(=O)N[C@H](Cc2ccccc2)C(O)=O)cc1[N+]([O-])=O
Show InChI InChI=1S/C23H26N4O7S/c1-14(28)24-17-8-7-16(12-20(17)27(33)34)13-21(29)25-18(9-10-35)22(30)26-19(23(31)32)11-15-5-3-2-4-6-15/h2-8,12,18-19,35H,9-11,13H2,1H3,(H,24,28)(H,25,29)(H,26,30)(H,31,32)/t18?,19-/m1/s1
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390n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50322612
PNG
(CHEMBL1173797 | alpha-Sulfanyl(2,4-dichlorobenzyl)...)
Show SMILES OP(O)(O)C(=S)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C7H7Cl2O3PS/c8-4-1-2-5(6(9)3-4)7(14)13(10,11)12/h1-3,10-13H
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400n/an/an/an/an/an/an/an/a



University of Li£ge

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia beta lactamase L1 in absence of Zn+ chelator


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50322612
PNG
(CHEMBL1173797 | alpha-Sulfanyl(2,4-dichlorobenzyl)...)
Show SMILES OP(O)(O)C(=S)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C7H7Cl2O3PS/c8-4-1-2-5(6(9)3-4)7(14)13(10,11)12/h1-3,10-13H
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400n/an/an/an/an/an/an/an/a



University of Li£ge

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia beta lactamase L1 in presence of Zn+ chelator


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50092978
PNG
(CHEMBL3586475)
Show SMILES C[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
Show InChI InChI=1/C11H13NO4S2/c1-7(11(16)18-6-10(14)15)12-9(13)5-8-3-2-4-17-8/h2-4,7H,5-6H2,1H3,(H,12,13)(H,14,15)/t7-/s2
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410n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191985
PNG
((2R)-2-(4-mercapto-2-(3-(trimethylsilyl)propanamid...)
Show SMILES C[Si](C)(C)CCC(=O)NC(CCS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H30N2O4SSi/c1-27(2,3)12-10-17(22)20-15(9-11-26)18(23)21-16(19(24)25)13-14-7-5-4-6-8-14/h4-8,15-16,26H,9-13H2,1-3H3,(H,20,22)(H,21,23)(H,24,25)/t15?,16-/m1/s1
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520n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191988
PNG
((2R)-2-(2-(4-hydroxy-3,5-dimethylbenzamido)-4-merc...)
Show SMILES Cc1cc(cc(C)c1O)C(=O)NC(CCS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H26N2O5S/c1-13-10-16(11-14(2)19(13)25)20(26)23-17(8-9-30)21(27)24-18(22(28)29)12-15-6-4-3-5-7-15/h3-7,10-11,17-18,25,30H,8-9,12H2,1-2H3,(H,23,26)(H,24,27)(H,28,29)/t17?,18-/m1/s1
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540n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191994
PNG
((2R)-2-(2-(5-hydroxy-1H-indole-2-carboxamido)-4-me...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cc(O)ccc2[nH]1
Show InChI InChI=1S/C22H23N3O5S/c26-15-6-7-16-14(11-15)12-18(23-16)21(28)24-17(8-9-31)20(27)25-19(22(29)30)10-13-4-2-1-3-5-13/h1-7,11-12,17,19,23,26,31H,8-10H2,(H,24,28)(H,25,27)(H,29,30)/t17?,19-/m1/s1
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570n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50322601
PNG
(CHEMBL1173800 | alpha-Sulfanyl(4-chlorobenzyl)phos...)
Show SMILES OP(O)(O)C(=S)c1ccc(Cl)cc1
Show InChI InChI=1S/C7H8ClO3PS/c8-6-3-1-5(2-4-6)7(13)12(9,10)11/h1-4,9-12H
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700n/an/an/an/an/an/an/an/a



University of Li£ge

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia beta lactamase L1 in presence of Zn+ chelator


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More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191993
PNG
((2R)-2-(2-(3-cyclohexylpropanamido)-4-mercaptobuta...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)CCC1CCCCC1
Show InChI InChI=1S/C22H32N2O4S/c25-20(12-11-16-7-3-1-4-8-16)23-18(13-14-29)21(26)24-19(22(27)28)15-17-9-5-2-6-10-17/h2,5-6,9-10,16,18-19,29H,1,3-4,7-8,11-15H2,(H,23,25)(H,24,26)(H,27,28)/t18?,19-/m1/s1
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780n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50191995
PNG
((2R)-2-(2-(2-(2-chloro-5-nitrophenyl)acetamido)-4-...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)Cc1cc(ccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C21H22ClN3O6S/c22-16-7-6-15(25(30)31)11-14(16)12-19(26)23-17(8-9-32)20(27)24-18(21(28)29)10-13-4-2-1-3-5-13/h1-7,11,17-18,32H,8-10,12H2,(H,23,26)(H,24,27)(H,28,29)/t17?,18-/m1/s1
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780n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50093027
PNG
(CHEMBL3586482)
Show SMILES OC(=O)CSC(=O)[C@@H]1CCCN1C(=O)Cc1cccs1
Show InChI InChI=1S/C35H46N4O9/c1-5-21(4)30(36-27(40)13-14-28(41)42)32(44)37-29(20(2)3)33(45)39-18-24(17-26(39)31(43)38-35(15-16-35)34(46)47)48-19-23-11-8-10-22-9-6-7-12-25(22)23/h6-12,20-21,24,26,29-30H,5,13-19H2,1-4H3,(H,36,40)(H,37,44)(H,38,43)(H,41,42)(H,46,47)/t21?,24-,26+,29+,30+/m1/s1
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870n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi...


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More data for this
Ligand-Target Pair
Beta-lactamase L1


(Stenotrophomonas maltophilia)
BDBM50192004
PNG
((2R)-2-(2-(3-butylpicolinamido)-3-mercaptopropanam...)
Show SMILES CCCCc1ccc(nc1)C(=O)NC(CS)C(=O)N[C@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H27N3O4S/c1-2-3-7-16-10-11-17(23-13-16)20(26)25-19(14-30)21(27)24-18(22(28)29)12-15-8-5-4-6-9-15/h4-6,8-11,13,18-19,30H,2-3,7,12,14H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t18-,19?/m1/s1
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880n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Inhibition of Stenotrophomonas maltophilia L1 metallo beta lactamase


Citation and Details
More data for this
Ligand-Target Pair
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