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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'CDC45-related protein'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDC45-related protein


(Homo sapiens)
BDBM50097530
PNG
(CHEMBL168868 | [5-(5-Cyano-1-methyl-pentyl)-1-(1,5...)
Show SMILES CC(C)CCCC(C)[C@H]1CC[C@H]2[C@H](CC(O)=O)[C@H](CC[C@]12C)C(C)CCCCC#N
Show InChI InChI=1S/C27H47NO2/c1-19(2)10-9-12-21(4)24-13-14-25-23(18-26(29)30)22(15-16-27(24,25)5)20(3)11-7-6-8-17-28/h19-25H,6-16,18H2,1-5H3,(H,29,30)/t20?,21?,22-,23-,24-,25+,27-/m1/s1
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PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



School of Chemistry and Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory activity tested against human cell division cycle 45-like 2


J Med Chem 44: 834-48 (2001)

More data for this
Ligand-Target Pair
CDC45-related protein


(Homo sapiens)
BDBM50097537
PNG
(CHEMBL262776 | [5-(5-Cyanomethyl-2-methyl-tetrahyd...)
Show SMILES CC(C)CCCC(C)[C@H]1CC[C@H]2[C@H](CC(O)=O)[C@H](CC[C@]12C)[C@@]1(C)CC[C@@H](CC#N)O1
Show InChI InChI=1S/C27H45NO3/c1-18(2)7-6-8-19(3)22-9-10-23-21(17-25(29)30)24(12-14-26(22,23)4)27(5)15-11-20(31-27)13-16-28/h18-24H,6-15,17H2,1-5H3,(H,29,30)/t19?,20-,21-,22+,23-,24-,26+,27+/m0/s1
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PubMed
n/an/a 1.58E+4n/an/an/an/an/an/a



School of Chemistry and Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory activity tested against human cell division cycle 45-like 2


J Med Chem 44: 834-48 (2001)

More data for this
Ligand-Target Pair
CDC45-related protein


(Homo sapiens)
BDBM50097534
PNG
(5-[3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-8-oxo-dode...)
Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC(=O)O[C@](C)(CCCCC(O)=O)[C@H]3CC[C@]12C
Show InChI InChI=1S/C27H46O4/c1-18(2)9-8-10-19(3)21-12-13-22-20-17-25(30)31-27(5,15-7-6-11-24(28)29)23(20)14-16-26(21,22)4/h18-23H,6-17H2,1-5H3,(H,28,29)/t19-,20+,21-,22+,23+,26-,27-/m1/s1
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Similars

AffyNet 
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



School of Chemistry and Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory activity tested against human cell division cycle 45-like 2


J Med Chem 44: 834-48 (2001)

More data for this
Ligand-Target Pair