Compile Data Set for Download or QSAR

Found 353 hits Enz. Inhib. hit(s) with Target = 'CDK9/cyclin T1'   

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126530 (US8778951, 341) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C23H28ClFN6O/c24-18-12-28-21(30-16-3-1-15(27)2-4-16)11-17(18)20-6-5-19(25)22(31-20)29-14-23(13-26)7-9-32-10-8-23/h5-6,11-12,15-16H,1-4,7-10,14,27H2,(H,28,30)(H,29,31)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000150	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126546 (US8778951, 357) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C23H27ClFN5O2/c24-18-12-27-21(29-15-1-3-16(31)4-2-15)11-17(18)20-6-5-19(25)22(30-20)28-14-23(13-26)7-9-32-10-8-23/h5-6,11-12,15-16,31H,1-4,7-10,14H2,(H,27,29)(H,28,30)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000160	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126547 (US8778951, 358) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6-13,16,18H2,1-2H3,(H,30,33)(H,31,34)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000170	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126528 (US8778951, 339) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C26H34ClFN6O2/c1-35-13-10-30-18-2-4-19(5-3-18)33-24-14-20(21(27)15-31-24)23-7-6-22(28)25(34-23)32-17-26(16-29)8-11-36-12-9-26/h6-7,14-15,18-19,30H,2-5,8-13,17H2,1H3,(H,31,33)(H,32,34)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000170	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126531 (US8778951, 342) Show SMILES CCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C26H34ClFN6O/c1-2-11-30-18-3-5-19(6-4-18)33-24-14-20(21(27)15-31-24)23-8-7-22(28)25(34-23)32-17-26(16-29)9-12-35-13-10-26/h7-8,14-15,18-19,30H,2-6,9-13,17H2,1H3,(H,31,33)(H,32,34)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000170	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126529 (US8778951, 340) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C27H36ClFN6O2/c1-18(15-36-2)33-19-3-5-20(6-4-19)34-25-13-21(22(28)14-31-25)24-8-7-23(29)26(35-24)32-17-27(16-30)9-11-37-12-10-27/h7-8,13-14,18-20,33H,3-6,9-12,15,17H2,1-2H3,(H,31,34)(H,32,35)/t18-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000230	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126548 (US8778951, 359) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C23H28ClN5O2/c24-19-13-26-22(28-16-4-6-17(30)7-5-16)12-18(19)20-2-1-3-21(29-20)27-15-23(14-25)8-10-31-11-9-23/h1-3,12-13,16-17,30H,4-11,15H2,(H,26,28)(H,27,29)/t16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000240	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126507 (US8778951, 318) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)c(F)cc1F Show InChI InChI=1S/C22H28ClF2N5O/c23-17-12-27-20(29-15-3-1-14(26)2-4-15)9-16(17)21-18(24)10-19(25)22(30-21)28-11-13-5-7-31-8-6-13/h9-10,12-15H,1-8,11,26H2,(H,27,29)(H,28,30)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000260	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126524 (US8778951, 335) Show SMILES CC1(N[C@H]2CC[C@@H](CC2)Nc2cc(c(Cl)cn2)-c2ccc(F)c(NCC3(CCOCC3)C#N)n2)OCCO1 Show InChI InChI=1S/C27H34ClFN6O3/c1-26(37-12-13-38-26)35-19-4-2-18(3-5-19)33-24-14-20(21(28)15-31-24)23-7-6-22(29)25(34-23)32-17-27(16-30)8-10-36-11-9-27/h6-7,14-15,18-19,35H,2-5,8-13,17H2,1H3,(H,31,33)(H,32,34)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000270	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126549 (US8778951, 360) Show SMILES CCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C25H33ClN6O/c1-2-28-18-6-8-19(9-7-18)31-24-14-20(21(26)15-29-24)22-4-3-5-23(32-22)30-17-25(16-27)10-12-33-13-11-25/h3-5,14-15,18-19,28H,2,6-13,17H2,1H3,(H,29,31)(H,30,32)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000280	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126500 (US8778951, 310) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6-13,16,18H2,1-2H3,(H,30,33)(H,31,34)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126502 (US8778951, 312) Show SMILES CC1(CNc2nc(ccc2F)-c2cc(N[C@H]3CC[C@H](N)CC3)ncc2Cl)CCOCC1 Show InChI InChI=1S/C23H31ClFN5O/c1-23(8-10-31-11-9-23)14-28-22-19(25)6-7-20(30-22)17-12-21(27-13-18(17)24)29-16-4-2-15(26)3-5-16/h6-7,12-13,15-16H,2-5,8-11,14,26H2,1H3,(H,27,29)(H,28,30)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126550 (US8778951, 361) Show SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C25H33ClN6O/c1-32(2)19-8-6-18(7-9-19)30-24-14-20(21(26)15-28-24)22-4-3-5-23(31-22)29-17-25(16-27)10-12-33-13-11-25/h3-5,14-15,18-19H,6-13,17H2,1-2H3,(H,28,30)(H,29,31)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126532 (US8778951, 343) Show SMILES CCCN(CCC)[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C29H40ClFN6O/c1-3-13-37(14-4-2)22-7-5-21(6-8-22)35-27-17-23(24(30)18-33-27)26-10-9-25(31)28(36-26)34-20-29(19-32)11-15-38-16-12-29/h9-10,17-18,21-22H,3-8,11-16,20H2,1-2H3,(H,33,35)(H,34,36)/t21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000310	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126551 (US8778951, 362) Show SMILES FC(F)(F)OCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C26H32ClF3N6O2/c27-21-15-33-24(35-19-6-4-18(5-7-19)32-10-13-38-26(28,29)30)14-20(21)22-2-1-3-23(36-22)34-17-25(16-31)8-11-37-12-9-25/h1-3,14-15,18-19,32H,4-13,17H2,(H,33,35)(H,34,36)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000360	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126552 (US8778951, 363) Show SMILES Clc1cnc(N[C@H]2CC[C@@H](CC2)NC2CCOCC2)cc1-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C28H37ClN6O2/c29-24-17-31-27(34-21-6-4-20(5-7-21)33-22-8-12-36-13-9-22)16-23(24)25-2-1-3-26(35-25)32-19-28(18-30)10-14-37-15-11-28/h1-3,16-17,20-22,33H,4-15,19H2,(H,31,34)(H,32,35)/t20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000430	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126515 (US8778951, 326) Show SMILES CS(=O)(=O)CCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2CCOCC2)n1 Show InChI InChI=1S/C25H35ClFN5O3S/c1-36(33,34)13-10-28-18-2-4-19(5-3-18)31-24-14-20(21(26)16-29-24)23-7-6-22(27)25(32-23)30-15-17-8-11-35-12-9-17/h6-7,14,16-19,28H,2-5,8-13,15H2,1H3,(H,29,31)(H,30,32)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000490	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126553 (US8778951, 364) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(F)CCOCC2)n1 Show InChI InChI=1S/C25H35ClFN5O2/c1-33-14-11-28-18-5-7-19(8-6-18)31-24-15-20(21(26)16-29-24)22-3-2-4-23(32-22)30-17-25(27)9-12-34-13-10-25/h2-4,15-16,18-19,28H,5-14,17H2,1H3,(H,29,31)(H,30,32)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000630	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126554 (US8778951, 365) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(C)CCS(=O)(=O)CC2)n1 Show InChI InChI=1S/C27H40ClN5O3S/c1-19(17-36-3)31-20-7-9-21(10-8-20)32-26-15-22(23(28)16-29-26)24-5-4-6-25(33-24)30-18-27(2)11-13-37(34,35)14-12-27/h4-6,15-16,19-21,31H,7-14,17-18H2,1-3H3,(H,29,32)(H,30,33)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.000700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126473 (US8778951, 283) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1F Show InChI InChI=1S/C25H35ClFN5O2/c1-33-13-10-28-18-2-4-19(5-3-18)31-24-14-20(21(26)16-30-24)25-22(27)6-7-23(32-25)29-15-17-8-11-34-12-9-17/h6-7,14,16-19,28H,2-5,8-13,15H2,1H3,(H,29,32)(H,30,31)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126555 (US8778951, 366) Show SMILES CCN(CC)[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 Show InChI InChI=1S/C27H37ClN6O/c1-3-34(4-2)21-10-8-20(9-11-21)32-26-16-22(23(28)17-30-26)24-6-5-7-25(33-24)31-19-27(18-29)12-14-35-15-13-27/h5-7,16-17,20-21H,3-4,8-15,19H2,1-2H3,(H,30,32)(H,31,33)/t20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126476 (US8778951, 286) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1Br Show InChI InChI=1S/C22H29BrClN5O/c23-18-5-6-20(26-12-14-7-9-30-10-8-14)29-22(18)17-11-21(27-13-19(17)24)28-16-3-1-15(25)2-4-16/h5-6,11,13-16H,1-4,7-10,12,25H2,(H,26,29)(H,27,28)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126481 (US8778951, 291) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1Cl Show InChI InChI=1S/C26H37Cl2N5O2/c1-17(16-34-2)31-19-3-5-20(6-4-19)32-25-13-21(23(28)15-30-25)26-22(27)7-8-24(33-26)29-14-18-9-11-35-12-10-18/h7-8,13,15,17-20,31H,3-6,9-12,14,16H2,1-2H3,(H,29,33)(H,30,32)/t17-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126483 (US8778951, 293) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1F Show InChI InChI=1S/C26H37ClFN5O2/c1-17(16-34-2)31-19-3-5-20(6-4-19)32-25-13-21(22(27)15-30-25)26-23(28)7-8-24(33-26)29-14-18-9-11-35-12-10-18/h7-8,13,15,17-20,31H,3-6,9-12,14,16H2,1-2H3,(H,29,33)(H,30,32)/t17-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126484 (US8778951, 294) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2CCOCC2)n1 Show InChI InChI=1S/C26H37ClFN5O2/c1-17(16-34-2)31-19-3-5-20(6-4-19)32-25-13-21(22(27)15-29-25)24-8-7-23(28)26(33-24)30-14-18-9-11-35-12-10-18/h7-8,13,15,17-20,31H,3-6,9-12,14,16H2,1-2H3,(H,29,32)(H,30,33)/t17-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126487 (US8778951, 297) Show SMILES CC1(C)CC(CNc2ccc(Cl)c(n2)-c2cc(N[C@H]3CC[C@H](O)CC3)ncc2Cl)CCO1 Show InChI InChI=1S/C24H32Cl2N4O2/c1-24(2)12-15(9-10-32-24)13-27-21-8-7-19(25)23(30-21)18-11-22(28-14-20(18)26)29-16-3-5-17(31)6-4-16/h7-8,11,14-17,31H,3-6,9-10,12-13H2,1-2H3,(H,27,30)(H,28,29)/t15?,16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126488 (US8778951, 298) Show SMILES CC1(C)CC(CNc2ccc(Cl)c(n2)-c2cc(N[C@H]3CC[C@@H](CC3)NC[C@H](O)C(F)(F)F)ncc2Cl)CCO1 Show InChI InChI=1S/C27H36Cl2F3N5O2/c1-26(2)12-16(9-10-39-26)13-34-23-8-7-20(28)25(37-23)19-11-24(35-14-21(19)29)36-18-5-3-17(4-6-18)33-15-22(38)27(30,31)32/h7-8,11,14,16-18,22,33,38H,3-6,9-10,12-13,15H2,1-2H3,(H,34,37)(H,35,36)/t16?,17-,18-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126489 (US8778951, 299) Show SMILES CC1(C)CC(CNc2ccc(Cl)c(n2)-c2cc(N[C@H]3CC[C@@H](CC3)NC[C@@H](O)C(F)(F)F)ncc2Cl)CCO1 Show InChI InChI=1S/C27H36Cl2F3N5O2/c1-26(2)12-16(9-10-39-26)13-34-23-8-7-20(28)25(37-23)19-11-24(35-14-21(19)29)36-18-5-3-17(4-6-18)33-15-22(38)27(30,31)32/h7-8,11,14,16-18,22,33,38H,3-6,9-10,12-13,15H2,1-2H3,(H,34,37)(H,35,36)/t16?,17-,18-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126492 (US8778951, 302) Show SMILES FC(F)(F)OCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1Cl Show InChI InChI=1S/C25H32Cl2F3N5O2/c26-20-5-6-22(32-14-16-7-10-36-11-8-16)35-24(20)19-13-23(33-15-21(19)27)34-18-3-1-17(2-4-18)31-9-12-37-25(28,29)30/h5-6,13,15-18,31H,1-4,7-12,14H2,(H,32,35)(H,33,34)/t17-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126495 (US8778951, 305) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)OC)n1 Show InChI InChI=1S/C27H40ClN5O3/c1-19(17-34-2)31-20-7-9-21(10-8-20)32-26-15-22(23(28)16-29-26)24-5-4-6-25(33-24)30-18-27(35-3)11-13-36-14-12-27/h4-6,15-16,19-21,31H,7-14,17-18H2,1-3H3,(H,29,32)(H,30,33)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126498 (US8778951, 308) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(c(NCC2CCOCC2)n1)C(F)(F)F Show InChI InChI=1S/C27H37ClF3N5O2/c1-17(16-37-2)34-19-3-5-20(6-4-19)35-25-13-21(23(28)15-32-25)24-8-7-22(27(29,30)31)26(36-24)33-14-18-9-11-38-12-10-18/h7-8,13,15,17-20,34H,3-6,9-12,14,16H2,1-2H3,(H,32,35)(H,33,36)/t17-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126501 (US8778951, 311) Show SMILES CC1(CNc2cccc(n2)-c2cc(N[C@H]3CC[C@H](N)CC3)ncc2Cl)CCOCC1 Show InChI InChI=1S/C23H32ClN5O/c1-23(9-11-30-12-10-23)15-27-21-4-2-3-20(29-21)18-13-22(26-14-19(18)24)28-17-7-5-16(25)6-8-17/h2-4,13-14,16-17H,5-12,15,25H2,1H3,(H,26,28)(H,27,29)/t16-,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126503 (US8778951, 313) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(F)CCOCC2)n1 Show InChI InChI=1S/C22H29ClFN5O/c23-18-13-26-21(28-16-6-4-15(25)5-7-16)12-17(18)19-2-1-3-20(29-19)27-14-22(24)8-10-30-11-9-22/h1-3,12-13,15-16H,4-11,14,25H2,(H,26,28)(H,27,29)/t15-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126504 (US8778951, 314) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(F)c(NCC2CCOCC2)n1 Show InChI InChI=1S/C25H35ClFN5O2/c1-33-13-10-28-18-2-4-19(5-3-18)31-24-14-20(21(26)16-29-24)23-7-6-22(27)25(32-23)30-15-17-8-11-34-12-9-17/h6-7,14,16-19,28H,2-5,8-13,15H2,1H3,(H,29,31)(H,30,32)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126509 (US8778951, 320) Show SMILES CC1(C)OC[C@@H](CN[C@H]2CC[C@@H](CC2)Nc2cc(c(Cl)cn2)-c2nc(NCC3CCOCC3)ccc2Cl)O1 Show InChI InChI=1S/C28H39Cl2N5O3/c1-28(2)37-17-21(38-28)15-31-19-3-5-20(6-4-19)34-26-13-22(24(30)16-33-26)27-23(29)7-8-25(35-27)32-14-18-9-11-36-12-10-18/h7-8,13,16,18-21,31H,3-6,9-12,14-15,17H2,1-2H3,(H,32,35)(H,33,34)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126512 (US8778951, 323) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NC[C@@H]2CCCOC2)ccc1Cl Show InChI InChI=1S/C26H37Cl2N5O2/c1-17(15-34-2)31-19-5-7-20(8-6-19)32-25-12-21(23(28)14-30-25)26-22(27)9-10-24(33-26)29-13-18-4-3-11-35-16-18/h9-10,12,14,17-20,31H,3-8,11,13,15-16H2,1-2H3,(H,29,33)(H,30,32)/t17-,18+,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126516 (US8778951, 327) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NC[C@H]2CCCOC2)ccc1Cl Show InChI InChI=1S/C26H37Cl2N5O2/c1-17(15-34-2)31-19-5-7-20(8-6-19)32-25-12-21(23(28)14-30-25)26-22(27)9-10-24(33-26)29-13-18-4-3-11-35-16-18/h9-10,12,14,17-20,31H,3-8,11,13,15-16H2,1-2H3,(H,29,33)(H,30,32)/t17-,18-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126517 (US8778951, 328) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NC[C@H]2CCOC(C)(C)C2)n1 Show InChI InChI=1S/C28H42ClN5O2/c1-19(18-35-4)32-21-8-10-22(11-9-21)33-27-14-23(24(29)17-31-27)25-6-5-7-26(34-25)30-16-20-12-13-36-28(2,3)15-20/h5-7,14,17,19-22,32H,8-13,15-16,18H2,1-4H3,(H,30,34)(H,31,33)/t19-,20+,21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126518 (US8778951, 329) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2CCOC(C)(C)C2)n1 Show InChI InChI=1S/C28H42ClN5O2/c1-19(18-35-4)32-21-8-10-22(11-9-21)33-27-14-23(24(29)17-31-27)25-6-5-7-26(34-25)30-16-20-12-13-36-28(2,3)15-20/h5-7,14,17,19-22,32H,8-13,15-16,18H2,1-4H3,(H,30,34)(H,31,33)/t19-,20?,21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126520 (US8778951, 331) Show SMILES Fc1ccc(nc1NCC1CCOCC1)-c1cc(N[C@H]2CC[C@@H](CC2)NCC2CCS(=O)(=O)CC2)ncc1Cl Show InChI InChI=1S/C28H39ClFN5O3S/c29-24-18-32-27(34-22-3-1-21(2-4-22)31-16-20-9-13-39(36,37)14-10-20)15-23(24)26-6-5-25(30)28(35-26)33-17-19-7-11-38-12-8-19/h5-6,15,18-22,31H,1-4,7-14,16-17H2,(H,32,34)(H,33,35)/t21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126521 (US8778951, 332) Show SMILES CC1(CNc2nc(ccc2F)-c2cc(N[C@H]3CC[C@@H](CC3)NC3CCS(=O)(=O)C3)ncc2Cl)CCOCC1 Show InChI InChI=1S/C27H37ClFN5O3S/c1-27(9-11-37-12-10-27)17-31-26-23(29)6-7-24(34-26)21-14-25(30-15-22(21)28)33-19-4-2-18(3-5-19)32-20-8-13-38(35,36)16-20/h6-7,14-15,18-20,32H,2-5,8-13,16-17H2,1H3,(H,30,33)(H,31,34)/t18-,19-,20?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126523 (US8778951, 334) Show SMILES CC1(N[C@H]2CC[C@@H](CC2)Nc2cc(c(Cl)cn2)-c2ccc(F)c(NCC3(C)CCOCC3)n2)OCCO1 Show InChI InChI=1S/C27H37ClFN5O3/c1-26(9-11-35-12-10-26)17-31-25-22(29)7-8-23(33-25)20-15-24(30-16-21(20)28)32-18-3-5-19(6-4-18)34-27(2)36-13-14-37-27/h7-8,15-16,18-19,34H,3-6,9-14,17H2,1-2H3,(H,30,32)(H,31,33)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126535 (US8778951, 346) Show SMILES CC1(CNc2nc(ccc2F)-c2cc(N[C@H]3CC[C@@H](CC3)NC3CCS(=O)(=O)CC3)ncc2Cl)CCOCC1 Show InChI InChI=1S/C28H39ClFN5O3S/c1-28(10-12-38-13-11-28)18-32-27-24(30)6-7-25(35-27)22-16-26(31-17-23(22)29)34-20-4-2-19(3-5-20)33-21-8-14-39(36,37)15-9-21/h6-7,16-17,19-21,33H,2-5,8-15,18H2,1H3,(H,31,34)(H,32,35)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126536 (US8778951, 347) Show SMILES CC1(CNc2nc(ccc2F)-c2cc(NC3CCC(CC3)NC3CS(=O)(=O)C3)ncc2Cl)CCOCC1 Show InChI InChI=1S/C26H35ClFN5O3S/c1-26(8-10-36-11-9-26)16-30-25-22(28)6-7-23(33-25)20-12-24(29-13-21(20)27)32-18-4-2-17(3-5-18)31-19-14-37(34,35)15-19/h6-7,12-13,17-19,31H,2-5,8-11,14-16H2,1H3,(H,29,32)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126538 (US8778951, 349) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CO)CCOCC2)n1 Show InChI InChI=1S/C27H40ClN5O3/c1-19(16-35-2)31-20-6-8-21(9-7-20)32-26-14-22(23(28)15-29-26)24-4-3-5-25(33-24)30-17-27(18-34)10-12-36-13-11-27/h3-5,14-15,19-21,31,34H,6-13,16-18H2,1-2H3,(H,29,32)(H,30,33)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126539 (US8778951, 350) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CO)CCOCC2)n1 Show InChI InChI=1S/C26H38ClN5O3/c1-34-14-11-28-19-5-7-20(8-6-19)31-25-15-21(22(27)16-29-25)23-3-2-4-24(32-23)30-17-26(18-33)9-12-35-13-10-26/h2-4,15-16,19-20,28,33H,5-14,17-18H2,1H3,(H,29,31)(H,30,32)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126474 (US8778951, 284) Show SMILES C[C@H]1CC(CNc2cccc(n2)-c2cc(N[C@H]3CC[C@H](N)CC3)ncc2Cl)C[C@@H](C)O1 Show InChI InChI=1S/C24H34ClN5O/c1-15-10-17(11-16(2)31-15)13-27-23-5-3-4-22(30-23)20-12-24(28-14-21(20)25)29-19-8-6-18(26)7-9-19/h3-5,12,14-19H,6-11,13,26H2,1-2H3,(H,27,30)(H,28,29)/t15-,16+,17?,18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126475 (US8778951, 285) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2C[C@H](C)O[C@H](C)C2)n1 Show InChI InChI=1S/C27H40ClN5O2/c1-18-13-20(14-19(2)35-18)16-30-26-6-4-5-25(33-26)23-15-27(31-17-24(23)28)32-22-9-7-21(8-10-22)29-11-12-34-3/h4-6,15,17-22,29H,7-14,16H2,1-3H3,(H,30,33)(H,31,32)/t18-,19+,20?,21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126480 (US8778951, 290) Show SMILES O[C@@H](CN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1nc(NCC2CCOCC2)ccc1Cl)C(F)(F)F Show InChI InChI=1S/C25H32Cl2F3N5O2/c26-19-5-6-22(32-12-15-7-9-37-10-8-15)35-24(19)18-11-23(33-13-20(18)27)34-17-3-1-16(2-4-17)31-14-21(36)25(28,29)30/h5-6,11,13,15-17,21,31,36H,1-4,7-10,12,14H2,(H,32,35)(H,33,34)/t16-,17-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair
CDK9/cyclin T1 (Homo sapiens (human))	BDBM126537 (US8778951, 348) Show SMILES Clc1ccc(NCC2CCOCC2)nc1-c1cc(NC2CCC(CC2)NC2CCS(=O)(=O)CC2)ncc1Cl Show InChI InChI=1S/C27H37Cl2N5O3S/c28-23-5-6-25(30-16-18-7-11-37-12-8-18)34-27(23)22-15-26(31-17-24(22)29)33-20-3-1-19(2-4-20)32-21-9-13-38(35,36)14-10-21/h5-6,15,17-21,32H,1-4,7-14,16H2,(H,30,34)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars AffyNet	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014)
					More data for this Ligand-Target Pair

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