BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 241 hits Enz. Inhib. hit(s) with Target = 'Cdc25C'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM107109
PNG
(US8592425, 8)
Show SMILES [NH3+][C@@H]1CCCC(F)(F)C1NC(=O)c1cc(cs1)-c1cnc2cc(cnn12)-c1ccc(F)cc1
Show InChI InChI=1S/C23H20F3N5OS/c24-16-5-3-13(4-6-16)14-9-20-28-11-18(31(20)29-10-14)15-8-19(33-12-15)22(32)30-21-17(27)2-1-7-23(21,25)26/h3-6,8-12,17,21H,1-2,7,27H2,(H,30,32)/p+1/t17-,21?/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 0.5n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...


US Patent US8592425 (2013)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50401900
PNG
(CHEMBL2207198)
Show SMILES O=C(NCCCNc1nc(Nc2ccc(cc2)N2CCOCC2)ncc1C1CC1)C1CCC1
Show InChI InChI=1S/C25H34N6O2/c32-24(19-3-1-4-19)27-12-2-11-26-23-22(18-5-6-18)17-28-25(30-23)29-20-7-9-21(10-8-20)31-13-15-33-16-14-31/h7-10,17-19H,1-6,11-16H2,(H,27,32)(H2,26,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of MARK3


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM107110
PNG
(US8592425, 14)
Show SMILES N[C@H]1CCCC(F)(F)C1NC(=O)c1cc(cs1)-c1cnc2cccnn12
Show InChI InChI=1S/C17H17F2N5OS/c18-17(19)5-1-3-11(20)15(17)23-16(25)13-7-10(9-26-13)12-8-21-14-4-2-6-22-24(12)14/h2,4,6-9,11,15H,1,3,5,20H2,(H,23,25)/t11-,15?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 15n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...


US Patent US8592425 (2013)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50401899
PNG
(CHEMBL2207208)
Show SMILES Cn1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1
Show InChI InChI=1S/C19H27N7O/c1-26-12-15(10-23-26)24-19-22-11-16(13-6-7-13)17(25-19)20-8-3-9-21-18(27)14-4-2-5-14/h10-14H,2-9H2,1H3,(H,21,27)(H2,20,22,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of MARK3


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM107108
PNG
(US8592425, 1)
Show SMILES Cc1sc(cc1-c1cnc2cccnn12)C(=O)NC1[C@H](N)CCCC1(F)F
Show InChI InChI=1S/C18H19F2N5OS/c1-10-11(13-9-22-15-5-3-7-23-25(13)15)8-14(27-10)17(26)24-16-12(21)4-2-6-18(16,19)20/h3,5,7-9,12,16H,2,4,6,21H2,1H3,(H,24,26)/t12-,16?/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 20n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...


US Patent US8592425 (2013)

More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50208827
PNG
(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Show SMILES OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 56.9n/an/an/an/an/an/a



Max-Planck-Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Inhibition of human Cdc25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175216
PNG
(5-(2-(dimethylamino)ethylamino)-2-ethylbenzo[d]oxa...)
Show SMILES CCc1nc2c(O)c(cc(O)c2o1)N=CCN(C)C
Show InChI InChI=1S/C13H17N3O3/c1-4-10-15-11-12(18)8(14-5-6-16(2)3)7-9(17)13(11)19-10/h5,7,17-18H,4,6H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175215
PNG
(6-(2-(dimethylamino)ethylamino)-2-ethylbenzo[d]oxa...)
Show SMILES CCc1nc2c(O)cc(N=CCN(C)C)c(O)c2o1
Show InChI InChI=1S/C13H17N3O3/c1-4-10-15-11-9(17)7-8(12(18)13(11)19-10)14-5-6-16(2)3/h5,7,17-18H,4,6H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM107111
PNG
(US8592425, 24)
Show SMILES CCc1sc(cc1-c1cnc2cc(C)cnn12)C(=O)NC1[C@H](N)CCCC1(F)F
Show InChI InChI=1S/C20H23F2N5OS/c1-3-15-12(14-10-24-17-7-11(2)9-25-27(14)17)8-16(29-15)19(28)26-18-13(23)5-4-6-20(18,21)22/h7-10,13,18H,3-6,23H2,1-2H3,(H,26,28)/t13-,18?/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 140n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...


US Patent US8592425 (2013)

More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175218
PNG
(5-(2-(dimethylamino)ethylamino)-2-methylbenzo[d]th...)
Show SMILES CN(C)CC=Nc1cc(O)c2sc(C)nc2c1O
Show InChI InChI=1S/C12H15N3O2S/c1-7-14-10-11(17)8(13-4-5-15(2)3)6-9(16)12(10)18-7/h4,6,16-17H,5H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50341995
PNG
(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Show SMILES CN(C)CC=Nc1c(C)c(O)c2sc(C)nc2c1O
Show InChI InChI=1S/C13H17N3O2S/c1-7-9(14-5-6-16(3)4)12(18)10-13(11(7)17)19-8(2)15-10/h5,17-18H,6H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Max-Planck-Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Inhibition of human Cdc25C


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50305006
PNG
(5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-i...)
Show SMILES NCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12
Show InChI InChI=1S/C23H19N7S/c24-5-6-30-12-17(22-18(30)11-26-23(25)28-22)14-7-15-10-27-29-21(15)16(8-14)20-9-13-3-1-2-4-19(13)31-20/h1-4,7-12H,5-6,24H2,(H,27,29)(H2,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CTAK1


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175219
PNG
(6-(2-(dimethylamino)ethylamino)-2-phenylbenzo[d]ox...)
Show SMILES CN(C)CC=Nc1cc(O)c2nc(oc2c1O)-c1ccccc1
Show InChI InChI=1S/C17H17N3O3/c1-20(2)9-8-18-12-10-13(21)14-16(15(12)22)23-17(19-14)11-6-4-3-5-7-11/h3-8,10,21-22H,9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175217
PNG
(5-(2-(dimethylamino)ethylamino)-2-phenylbenzo[d]ox...)
Show SMILES CN(C)CC=Nc1cc(O)c2oc(nc2c1O)-c1ccccc1
Show InChI InChI=1S/C17H17N3O3/c1-20(2)9-8-18-12-10-13(21)16-14(15(12)22)19-17(23-16)11-6-4-3-5-7-11/h3-8,10,21-22H,9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50106497
PNG
(6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline...)
Show SMILES Oc1c(Cl)c(N=CCN2CCOCC2)c(O)c2ncccc12
Show InChI InChI=1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-4,20-21H,5-9H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM107107
PNG
(US8592425, 92)
Show SMILES N[C@H]1CCCC(F)(F)C1NC(=O)c1nc(c(Cl)s1)-c1cnc2ccccn12
Show InChI InChI=1S/C17H16ClF2N5OS/c18-14-12(10-8-22-11-5-1-2-7-25(10)11)23-16(27-14)15(26)24-13-9(21)4-3-6-17(13,19)20/h1-2,5,7-9,13H,3-4,6,21H2,(H,24,26)/t9-,13?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 720n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...


US Patent US8592425 (2013)

More data for this
Ligand-Target Pair
MAP-Microtubule Affinity-Regulating Kinase 3 (MARK3)


(Homo sapiens (Human))
BDBM25017
PNG
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem
AffyNet 
Article
PubMed
n/an/a 2.20E+3n/an/an/an/a7.522



University of Dundee



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe...


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50177318
PNG
(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Show SMILES CCCCCCCCCCCCCCc1ccc(cc1)C(=O)c1ccc2c(nocc12)-c1ccc(OCC(O)=O)cc1
Show InChI InChI=1S/C36H43NO5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-27-15-17-29(18-16-27)36(40)32-24-23-31-33(32)25-42-37-35(31)28-19-21-30(22-20-28)41-26-34(38)39/h15-25H,2-14,26H2,1H3,(H,38,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.27E+3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against cdc25C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129579
PNG
(2,5-Dihydroxy-3-[7-(2-methyl-benzyl)-1H-indol-3-yl...)
Show SMILES Cc1ccccc1Cc1cccc2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C22H17NO4/c1-12-5-2-3-6-13(12)9-14-7-4-8-15-16(11-23-20(14)15)19-21(26)17(24)10-18(25)22(19)27/h2-8,11,19,23H,9-10H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129576
PNG
(2,5-Dihydroxy-3-[7-(3,7,11-trimethyl-dodeca-2,6,10...)
Show SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\Cc1cccc2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C29H33NO4/c1-18(2)8-5-9-19(3)10-6-11-20(4)14-15-21-12-7-13-22-23(17-30-27(21)22)26-28(33)24(31)16-25(32)29(26)34/h7-8,10,12-14,17,26,30H,5-6,9,11,15-16H2,1-4H3/b19-10+,20-14+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50218700
PNG
(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Show SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(CC(=O)Nc4ccc(cc4)N4CCOCC4)cc3NC2=O)c1
Show InChI InChI=1S/C32H31N5O4/c1-40-30-19-22(4-10-26(30)33)21-3-9-25-28(18-21)35-27-11-2-20(16-29(27)36-32(25)39)17-31(38)34-23-5-7-24(8-6-23)37-12-14-41-15-13-37/h2-11,16,18-19,35H,12-15,17,33H2,1H3,(H,34,38)(H,36,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.65E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant cTAK by radiometric assay


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50155597
PNG
(4-Dimethylamino-2-{[2-(4-nitro-phenyl)-ethylamino]...)
Show SMILES CN(C)c1ccc(O)c(CNCCc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C17H21N3O3/c1-19(2)16-7-8-17(21)14(11-16)12-18-10-9-13-3-5-15(6-4-13)20(22)23/h3-8,11,18,21H,9-10,12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory concentration for human cell division cycle 25 degree C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50155595
PNG
(4-Dimethylamino-2-methoxy-6-{[2-(4-nitro-phenyl)-e...)
Show SMILES COc1cc(cc(CNCCc2ccc(cc2)[N+]([O-])=O)c1O)N(C)C
Show InChI InChI=1S/C18H23N3O4/c1-20(2)16-10-14(18(22)17(11-16)25-3)12-19-9-8-13-4-6-15(7-5-13)21(23)24/h4-7,10-11,19,22H,8-9,12H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory concentration for human cell division cycle 25 degree C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197854
PNG
(3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Show SMILES CCCCCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C24H40O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-21(18-19-22(25)26)24(28)29-23(20)27/h2-19H2,1H3,(H,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



Université Paul Verlaine-Metz

Curated by ChEMBL


Assay Description
Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197854
PNG
(3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Show SMILES CCCCCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C24H40O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-21(18-19-22(25)26)24(28)29-23(20)27/h2-19H2,1H3,(H,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



Max-Planck-Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Inhibition of human Cdc25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50370437
PNG
(BN-82002 | CHEMBL1258871)
Show SMILES COc1cc(cc(CN(C)CCc2ccc(cc2)[N+]([O-])=O)c1C)N(C)C
Show InChI InChI=1S/C20H27N3O3/c1-15-17(12-19(21(2)3)13-20(15)26-5)14-22(4)11-10-16-6-8-18(9-7-16)23(24)25/h6-9,12-13H,10-11,14H2,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory concentration for human cell division cycle 25 degree C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50155599
PNG
(4-Dimethylamino-2-({methyl-[2-(4-nitro-phenyl)-eth...)
Show SMILES CN(C)c1ccc(O)c(CN(C)CCc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C18H23N3O3/c1-19(2)17-8-9-18(22)15(12-17)13-20(3)11-10-14-4-6-16(7-5-14)21(23)24/h4-9,12,22H,10-11,13H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory concentration for human cell division cycle 25 degree C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197848
PNG
(3-(4-tridecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)prop...)
Show SMILES CCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C20H32O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-17(14-15-18(21)22)20(24)25-19(16)23/h2-15H2,1H3,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.70E+3n/an/an/an/an/an/a



Université Paul Verlaine-Metz

Curated by ChEMBL


Assay Description
Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50068031
PNG
(CHEMBL142455 | [(1R,3aS,4R,5S,7aR)-5-(5-Cyano-1-me...)
Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@H](CC(O)=O)[C@H](CC[C@]12C)C(=C)CCCCC#N
Show InChI InChI=1S/C27H45NO2/c1-19(2)10-9-12-21(4)24-13-14-25-23(18-26(29)30)22(15-16-27(24,25)5)20(3)11-7-6-8-17-28/h19,21-25H,3,6-16,18H2,1-2,4-5H3,(H,29,30)/t21-,22-,23-,24-,25+,27-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



School of Chemistry and Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory activity tested against Human cell division cycle 25 degree C


J Med Chem 44: 834-48 (2001)

More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129584
PNG
(3-(7-Benzyloxy-1H-indol-3-yl)-2,5-dihydroxy-[1,4]b...)
Show SMILES O=C1CC(=O)C(=O)C(c2c[nH]c3c(OCc4ccccc4)cccc23)C1=O
Show InChI InChI=1S/C21H15NO5/c23-15-9-16(24)21(26)18(20(15)25)14-10-22-19-13(14)7-4-8-17(19)27-11-12-5-2-1-3-6-12/h1-8,10,18,22H,9,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197856
PNG
(3-(4-pentadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Show SMILES CCCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C22H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-19(16-17-20(23)24)22(26)27-21(18)25/h2-17H2,1H3,(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



Université Paul Verlaine-Metz

Curated by ChEMBL


Assay Description
Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197852
PNG
((Z )-3-(4-(heptadec-8-enyl)-2,5-dioxo-2,5-dihydrof...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C24H38O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-21(18-19-22(25)26)24(28)29-23(20)27/h9-10H,2-8,11-19H2,1H3,(H,25,26)/b10-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



Université Paul Verlaine-Metz

Curated by ChEMBL


Assay Description
Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129580
PNG
(3-[4,6-Dichloro-7-(3-methyl-but-2-enyl)-1H-indol-3...)
Show SMILES CC(C)=CCc1c(Cl)cc(Cl)c2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C19H15Cl2NO4/c1-8(2)3-4-9-11(20)5-12(21)15-10(7-22-17(9)15)16-18(25)13(23)6-14(24)19(16)26/h3,5,7,16,22H,4,6H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50001733
PNG
(CHEMBL3133821)
Show SMILES Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1
Show InChI InChI=1S/C17H13N3O/c21-12-5-3-4-11(10-12)19-15-8-9-18-17-16(15)13-6-1-2-7-14(13)20-17/h1-10,21H,(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Martin-Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human MARK3


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50218709
PNG
(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Show SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(cc3NC2=O)C(C)(C)C(=O)Nc2ccc(cc2)N2CCOCC2)c1
Show InChI InChI=1S/C34H35N5O4/c1-34(2,33(41)36-24-7-9-25(10-8-24)39-14-16-43-17-15-39)23-6-13-28-30(20-23)38-32(40)26-11-4-21(18-29(26)37-28)22-5-12-27(35)31(19-22)42-3/h4-13,18-20,37H,14-17,35H2,1-3H3,(H,36,41)(H,38,40)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant cTAK by radiometric assay


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM26613
PNG
((2E)-3-{3-[dihydroxy(oxo)-$l^{5}-stibanyl]phenyl}p...)
Show SMILES OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O
Show InChI InChI=1S/C9H7O2.2H2O.O.Sb/c10-9(11)7-6-8-4-2-1-3-5-8;;;;/h1-2,4-7H,(H,10,11);2*1H2;;/q;;;;+2/p-2/b7-6+;;;;
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His-tagged Cdc25c catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50177316
PNG
(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Show SMILES NCc1ccc(cc1)C(=O)c1ccc2c(nocc12)-c1ccc(OCC(O)=O)cc1
Show InChI InChI=1S/C23H18N2O5/c24-11-14-1-3-16(4-2-14)23(28)19-10-9-18-20(19)12-30-25-22(18)15-5-7-17(8-6-15)29-13-21(26)27/h1-10,12H,11,13,24H2,(H,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against cdc25C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129583
PNG
(3-[7-(3,7-Dimethyl-octa-2,6-dienyl)-1H-indol-3-yl]...)
Show SMILES CC(C)=CCC\C(C)=C\Cc1cccc2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C24H25NO4/c1-14(2)6-4-7-15(3)10-11-16-8-5-9-17-18(13-25-22(16)17)21-23(28)19(26)12-20(27)24(21)29/h5-6,8-10,13,21,25H,4,7,11-12H2,1-3H3/b15-10+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase c-TAK1


(Homo sapiens (Human))
BDBM50173609
PNG
(CHEMBL363648 | N-[4-(2-Ethyl-4-m-tolyl-thiazol-5-y...)
Show SMILES CCc1nc(c(s1)-c1ccnc(NC(=O)c2ccccc2)c1)-c1cccc(C)c1
Show InChI InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Mitogen-activated protein kinase kinase kinase 7 (TAK1)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129581
PNG
(3-[6-Chloro-7-(3-methyl-but-2-enyl)-1H-indol-3-yl]...)
Show SMILES CC(C)=CCc1c(Cl)ccc2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C19H16ClNO4/c1-9(2)3-4-11-13(20)6-5-10-12(8-21-17(10)11)16-18(24)14(22)7-15(23)19(16)25/h3,5-6,8,16,21H,4,7H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175220
PNG
(5-(2-(dimethylamino)ethylamino)-2-ethyl-1H-benzo[d...)
Show SMILES CCc1nc2c(O)cc(N=CCN(C)C)c(O)c2[nH]1
Show InChI InChI=1S/C13H18N4O2/c1-4-10-15-11-9(18)7-8(13(19)12(11)16-10)14-5-6-17(2)3/h5,7,18-19H,4,6H2,1-3H3,(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175222
PNG
(6-(2-(dimethylamino)ethylamino)-2-phenyl-2H-indazo...)
Show SMILES CN(C)CC=Nc1cc(O)c2cn(nc2c1O)-c1ccccc1
Show InChI InChI=1S/C17H18N4O2/c1-20(2)9-8-18-14-10-15(22)13-11-21(19-16(13)17(14)23)12-6-4-3-5-7-12/h3-8,10-11,22-23H,9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175223
PNG
(5-(2-(dimethylamino)ethylamino)-2-phenyl-2H-indazo...)
Show SMILES CN(C)CC=Nc1cc(O)c2nn(cc2c1O)-c1ccccc1
Show InChI InChI=1S/C17H18N4O2/c1-20(2)9-8-18-14-10-15(22)16-13(17(14)23)11-21(19-16)12-6-4-3-5-7-12/h3-8,10-11,22-23H,9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50197855
PNG
(3-(4-tetradecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)pr...)
Show SMILES CCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O
Show InChI InChI=1S/C21H34O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-18(15-16-19(22)23)21(25)26-20(17)24/h2-16H2,1H3,(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Université Paul Verlaine-Metz

Curated by ChEMBL


Assay Description
Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129574
PNG
(2,5-Dihydroxy-3-[7-(3-methyl-but-2-enyl)-1H-indol-...)
Show SMILES CC(C)=CCc1cccc2c(c[nH]c12)C1C(=O)C(=O)CC(=O)C1=O
Show InChI InChI=1S/C19H17NO4/c1-10(2)6-7-11-4-3-5-12-13(9-20-17(11)12)16-18(23)14(21)8-15(22)19(16)24/h3-6,9,16,20H,7-8H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129585
PNG
(3-(7-Benzyl-1H-indol-3-yl)-2,5-dihydroxy-[1,4]benz...)
Show SMILES O=C1CC(=O)C(=O)C(c2c[nH]c3c(Cc4ccccc4)cccc23)C1=O
Show InChI InChI=1S/C21H15NO4/c23-16-10-17(24)21(26)18(20(16)25)15-11-22-19-13(7-4-8-14(15)19)9-12-5-2-1-3-6-12/h1-8,11,18,22H,9-10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50129572
PNG
(3-(1H-Benzo[g]indol-3-yl)-2,5-dihydroxy-[1,4]benzo...)
Show SMILES O=C1CC(=O)C(=O)C(c2c[nH]c3c2ccc2ccccc32)C1=O
Show InChI InChI=1S/C18H11NO4/c20-13-7-14(21)18(23)15(17(13)22)12-8-19-16-10-4-2-1-3-9(10)5-6-11(12)16/h1-6,8,15,19H,7H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Duke University

Curated by ChEMBL


Assay Description
Eight point inhibitory concentration against Cell division cycle 25 degree C was determined


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM50175221
PNG
(5-(2-(dimethylamino)ethylamino)-2-phenyl-1H-benzo[...)
Show SMILES CN(C)CC=Nc1cc(O)c2nc([nH]c2c1O)-c1ccccc1
Show InChI InChI=1S/C17H18N4O2/c1-21(2)9-8-18-12-10-13(22)14-15(16(12)23)20-17(19-14)11-6-4-3-5-7-11/h3-8,10,22-23H,9H2,1-2H3,(H,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM24778
PNG
(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Show SMILES CC1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.88E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory concentration for human cell division cycle 25 degree C phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Cdc25C


(Homo sapiens (Human))
BDBM24778
PNG
(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Show SMILES CC1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant CDC25C


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 241 total )  |  Next  |  Last  >>
Jump to: