BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 100 hits Enz. Inhib. hit(s) with Target = 'Cell division protein ftsZ'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division protein FtsZ


(Escherichia coli)
BDBM50439495
PNG
(CHEMBL2418095)
Show SMILES Oc1cc(O)c2Oc3cc(C\C=C(Cl)/Cc4cc(O)c(Oc5cc(C\C=C(Cl)/Cc2c1)c(O)cc5Cl)c(O)c4)c(O)cc3Cl
Show InChI InChI=1S/C32H24Cl4O8/c33-19-3-1-16-10-29(22(35)13-24(16)38)43-31-18(9-21(37)12-28(31)42)8-20(34)4-2-17-11-30(23(36)14-25(17)39)44-32-26(40)6-15(5-19)7-27(32)41/h3-4,6-7,9-14,37-42H,1-2,5,8H2/b19-3+,20-4+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 6.70n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50079359
PNG
(VIRIDITOXIN | Viriditoxin)
Show SMILES COC(=O)CC1Cc2cc3cc(OC)c(c(O)c3c(O)c2C(=O)O1)-c1c(OC)cc2cc3CC(CC(=O)OC)OC(=O)c3c(O)c2c1O
Show InChI InChI=1/C34H30O14/c1-43-19-9-15-5-13-7-17(11-21(35)45-3)47-33(41)25(13)29(37)23(15)31(39)27(19)28-20(44-2)10-16-6-14-8-18(12-22(36)46-4)48-34(42)26(14)30(38)24(16)32(28)40/h5-6,9-10,17-18,37-40H,7-8,11-12H2,1-4H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50079359
PNG
(VIRIDITOXIN | Viriditoxin)
Show SMILES COC(=O)CC1Cc2cc3cc(OC)c(c(O)c3c(O)c2C(=O)O1)-c1c(OC)cc2cc3CC(CC(=O)OC)OC(=O)c3c(O)c2c1O
Show InChI InChI=1/C34H30O14/c1-43-19-9-15-5-13-7-17(11-21(35)45-3)47-33(41)25(13)29(37)23(15)31(39)27(19)28-20(44-2)10-16-6-14-8-18(12-22(36)46-4)48-34(42)26(14)30(38)24(16)32(28)40/h5-6,9-10,17-18,37-40H,7-8,11-12H2,1-4H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.20n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ polymerization


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50083355
PNG
(CHEMBL3423282)
Show SMILES Cc1nc2ccccc2n1C(=O)\C=C\c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C17H12Cl2N2O/c1-11-20-15-4-2-3-5-16(15)21(11)17(22)9-7-12-6-8-13(18)10-14(12)19/h2-10H,1H3/b9-7+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli ATCC 25922 recombinant N-His6-tagged FtsZ polymerization expressed in Escherichia coli BL21(DE3) incubated for 15 mins...


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50079356
PNG
(CHEMBL511201)
Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F
Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cell division protein FtsZ


(Escherichia coli)
BDBM50203065
PNG
(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)
Show SMILES O=C\C=C\c1ccccc1
Show InChI InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 5.81E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50335238
PNG
(5-Benzamido-2-cyclohexyl-6-N,N-diethylamino-1H-ben...)
Show SMILES CCN(CC)c1cc2[nH]c(nc2cc1NC(=O)c1ccccc1)C1CCCCC1
Show InChI InChI=1S/C24H30N4O/c1-3-28(4-2)22-16-20-19(25-23(26-20)17-11-7-5-8-12-17)15-21(22)27-24(29)18-13-9-6-10-14-18/h6,9-10,13-17H,3-5,7-8,11-12H2,1-2H3,(H,25,26)(H,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 6.21E+3n/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50203065
PNG
(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)
Show SMILES O=C\C=C\c1ccccc1
Show InChI InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 6.86E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ polymerization


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50335239
PNG
(CHEMBL1651202 | butyl 2-cyclohexyl-6-(diethylamino...)
Show SMILES CCCCOC(=O)Nc1cc2nc([nH]c2cc1N(CC)CC)C1CCCCC1
Show InChI InChI=1S/C22H34N4O2/c1-4-7-13-28-22(27)25-19-14-17-18(15-20(19)26(5-2)6-3)24-21(23-17)16-11-9-8-10-12-16/h14-16H,4-13H2,1-3H3,(H,23,24)(H,25,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 7.69E+3n/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50079361
PNG
(CHEMBL3416824)
Show SMILES Oc1ccccc1Cc1ccc(O)c(Cc2c(O)c(Cc3cc(Cc4ccccc4O)ccc3O)c3O[C@@H](CC(=O)c3c2O)c2ccccc2)c1
Show InChI InChI=1/C43H36O8/c44-34-12-6-4-10-28(34)18-25-14-16-36(46)30(20-25)22-32-41(49)33(23-31-21-26(15-17-37(31)47)19-29-11-5-7-13-35(29)45)43-40(42(32)50)38(48)24-39(51-43)27-8-2-1-3-9-27/h1-17,20-21,39,44-47,49-50H,18-19,22-24H2/t39-/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.30E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086108
PNG
(CHEMBL3425702)
Show SMILES [O-]C(=O)C(F)(F)F.[NH3+]CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C22H19ClN4/c23-18-8-5-15(6-9-18)7-10-21-26-20-14-17-4-2-1-3-16(17)13-19(20)22(27-21)25-12-11-24/h1-10,13-14H,11-12,24H2,(H,25,26,27)/p+1/b10-7+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50079358
PNG
(CHEMBL3416948)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C24H23ClN4/c1-29(2)14-13-26-24-21-15-18-5-3-4-6-19(18)16-22(21)27-23(28-24)12-9-17-7-10-20(25)11-8-17/h3-12,15-16H,13-14H2,1-2H3,(H,26,27,28)/b12-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50079360
PNG
(CHEBI:69681 | DICHAMANETIN | Dichamanetin)
Show SMILES Oc1ccccc1Cc1c(O)c(Cc2ccccc2O)c2O[C@@H](CC(=O)c2c1O)c1ccccc1
Show InChI InChI=1/C29H24O6/c30-22-12-6-4-10-18(22)14-20-27(33)21(15-19-11-5-7-13-23(19)31)29-26(28(20)34)24(32)16-25(35-29)17-8-2-1-3-9-17/h1-13,25,30-31,33-34H,14-16H2/t25-/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.25E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086088
PNG
(CHEMBL3425706)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)N=[N+]=[N-])nc2cc3ccccc3cc12
Show InChI InChI=1S/C24H23N7/c1-31(2)14-13-26-24-21-15-18-5-3-4-6-19(18)16-22(21)27-23(28-24)12-9-17-7-10-20(11-8-17)29-30-25/h3-12,15-16H,13-14H2,1-2H3,(H,26,27,28)/b12-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359406
PNG
(CHEMBL1926717)
Show SMILES CCOC(=O)Nc1cc(NCCCCN(CC)CC)c2nc(-c3ccco3)c(nc2n1)-c1ccco1
Show InChI InChI=1S/C26H32N6O4/c1-4-32(5-2)14-8-7-13-27-18-17-21(29-26(33)34-6-3)28-25-22(18)30-23(19-11-9-15-35-19)24(31-25)20-12-10-16-36-20/h9-12,15-17H,4-8,13-14H2,1-3H3,(H2,27,28,29,31,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.64E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359412
PNG
(CHEMBL1926724)
Show SMILES CCN(CC)CCCC(C)Nc1cc(N)nc2nc(-c3ccco3)c(nc12)-c1ccco1
Show InChI InChI=1S/C24H30N6O2/c1-4-30(5-2)12-6-9-16(3)26-17-15-20(25)27-24-21(17)28-22(18-10-7-13-31-18)23(29-24)19-11-8-14-32-19/h7-8,10-11,13-16H,4-6,9,12H2,1-3H3,(H3,25,26,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.86E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359407
PNG
(CHEMBL1926719)
Show SMILES CCOC(=O)Nc1cc(NCCN(CC)CC)c2nc(-c3cccs3)c(nc2n1)-c1cccs1
Show InChI InChI=1S/C24H28N6O2S2/c1-4-30(5-2)12-11-25-16-15-19(27-24(31)32-6-3)26-23-20(16)28-21(17-9-7-13-33-17)22(29-23)18-10-8-14-34-18/h7-10,13-15H,4-6,11-12H2,1-3H3,(H2,25,26,27,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086206
PNG
(CHEMBL3425606)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(C)cc12
Show InChI InChI=1S/C21H23ClN4/c1-15-4-10-19-18(14-15)21(23-12-13-26(2)3)25-20(24-19)11-7-16-5-8-17(22)9-6-16/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)/b11-7+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein ftsZ


(Bacillus subtilis)
BDBM50392993
PNG
(TOTAROL)
Show SMILES CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C
Show InChI InChI=1S/C20H30O/c1-13(2)18-14-7-10-17-19(3,4)11-6-12-20(17,5)15(14)8-9-16(18)21/h8-9,13,17,21H,6-7,10-12H2,1-5H3/t17-,20+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 2.40E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Bacillus subtilis FtsZ GTPase activity by enzyme-coupled assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086098
PNG
(CHEMBL3425705)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(I)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C24H23IN4/c1-29(2)14-13-26-24-21-15-18-5-3-4-6-19(18)16-22(21)27-23(28-24)12-9-17-7-10-20(25)11-8-17/h3-12,15-16H,13-14H2,1-2H3,(H,26,27,28)/b12-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086123
PNG
(CHEMBL3425694)
Show SMILES CN(C)CCOc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C24H22ClN3O/c1-28(2)13-14-29-24-21-15-18-5-3-4-6-19(18)16-22(21)26-23(27-24)12-9-17-7-10-20(25)11-8-17/h3-12,15-16H,13-14H2,1-2H3/b12-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359400
PNG
(CHEMBL1929425)
Show SMILES CCOC(=O)Nc1cc(NC(C)CCCN(CC)CC)c2nc(-c3ccco3)c(nc2n1)-c1ccco1
Show InChI InChI=1S/C27H34N6O4/c1-5-33(6-2)14-8-11-18(4)28-19-17-22(30-27(34)35-7-3)29-26-23(19)31-24(20-12-9-15-36-20)25(32-26)21-13-10-16-37-21/h9-10,12-13,15-18H,5-8,11,14H2,1-4H3,(H2,28,29,30,32,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.68E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086124
PNG
(CHEMBL3425693)
Show SMILES [O-]C(=O)C(F)(F)F.Cc1ccc2nc(\C=C\c3ccc(Cl)cc3)nc(NCC[NH3+])c2c1
Show InChI InChI=1S/C19H19ClN4/c1-13-2-8-17-16(12-13)19(22-11-10-21)24-18(23-17)9-5-14-3-6-15(20)7-4-14/h2-9,12H,10-11,21H2,1H3,(H,22,23,24)/p+1/b9-5+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359410
PNG
(CHEMBL1926722)
Show SMILES CCOC(=O)Nc1cc(NCCN(C)C)c2nc(-c3cccs3)c(nc2n1)-c1cccs1
Show InChI InChI=1S/C22H24N6O2S2/c1-4-30-22(29)25-17-13-14(23-9-10-28(2)3)18-21(24-17)27-20(16-8-6-12-32-16)19(26-18)15-7-5-11-31-15/h5-8,11-13H,4,9-10H2,1-3H3,(H2,23,24,25,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.73E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086201
PNG
(CHEMBL3425611)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C26H25ClN4/c1-31(2)17-16-28-26-23-18-21(20-6-4-3-5-7-20)11-14-24(23)29-25(30-26)15-10-19-8-12-22(27)13-9-19/h3-15,18H,16-17H2,1-2H3,(H,28,29,30)/b15-10+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359413
PNG
(CHEMBL1926725)
Show SMILES CCN(CC)CCCC(C)Nc1cc(N)nc2nc(-c3cccs3)c(nc12)-c1cccs1
Show InChI InChI=1S/C24H30N6S2/c1-4-30(5-2)12-6-9-16(3)26-17-15-20(25)27-24-21(17)28-22(18-10-7-13-31-18)23(29-24)19-11-8-14-32-19/h7-8,10-11,13-16H,4-6,9,12H2,1-3H3,(H3,25,26,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.95E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein ftsZ


(Bacillus subtilis)
BDBM50067040
PNG
(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O
Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis FtsZ polymerization


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086203
PNG
(CHEMBL3425609)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(Br)cc12
Show InChI InChI=1S/C20H20BrClN4/c1-26(2)12-11-23-20-17-13-15(21)6-9-18(17)24-19(25-20)10-5-14-3-7-16(22)8-4-14/h3-10,13H,11-12H2,1-2H3,(H,23,24,25)/b10-5+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086200
PNG
(CHEMBL3425612)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1ccncc1
Show InChI InChI=1S/C25H24ClN5/c1-31(2)16-15-28-25-22-17-20(19-11-13-27-14-12-19)6-9-23(22)29-24(30-25)10-5-18-3-7-21(26)8-4-18/h3-14,17H,15-16H2,1-2H3,(H,28,29,30)/b10-5+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359411
PNG
(CHEMBL1926723)
Show SMILES CCOC(=O)Nc1cc(NCCN(C)C)c2nc(-c3ccco3)c(nc2n1)-c1ccco1
Show InChI InChI=1S/C22H24N6O4/c1-4-30-22(29)25-17-13-14(23-9-10-28(2)3)18-21(24-17)27-20(16-8-6-12-32-16)19(26-18)15-7-5-11-31-15/h5-8,11-13H,4,9-10H2,1-3H3,(H2,23,24,25,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.41E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359398
PNG
(CHEMBL110168)
Show SMILES CCOC(=O)Nc1cc(NC(C)CCCN(CC)CC)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1
Show InChI InChI=1S/C31H38N6O2/c1-5-37(6-2)20-14-15-22(4)32-25-21-26(34-31(38)39-7-3)33-30-29(25)35-27(23-16-10-8-11-17-23)28(36-30)24-18-12-9-13-19-24/h8-13,16-19,21-22H,5-7,14-15,20H2,1-4H3,(H2,32,33,34,36,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 3.42E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359401
PNG
(CHEMBL1929426)
Show SMILES CCOC(=O)Nc1cc(NC(C)CCCN(CC)CC)c2nc(-c3cccs3)c(nc2n1)-c1cccs1
Show InChI InChI=1S/C27H34N6O2S2/c1-5-33(6-2)14-8-11-18(4)28-19-17-22(30-27(34)35-7-3)29-26-23(19)31-24(20-12-9-15-36-20)25(32-26)21-13-10-16-37-21/h9-10,12-13,15-18H,5-8,11,14H2,1-4H3,(H2,28,29,30,32,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.43E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359408
PNG
(CHEMBL1926720)
Show SMILES CCOC(=O)Nc1cc(NCCN(CC)CC)c2nc(-c3ccco3)c(nc2n1)-c1ccco1
Show InChI InChI=1S/C24H28N6O4/c1-4-30(5-2)12-11-25-16-15-19(27-24(31)32-6-3)26-23-20(16)28-21(17-9-7-13-33-17)22(29-23)18-10-8-14-34-18/h7-10,13-15H,4-6,11-12H2,1-3H3,(H2,25,26,27,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.48E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 3.60E+4n/an/an/an/an/an/a



THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...


US Patent US9169182 (2015)

More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.70E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus FtsZ GTPase activity


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359399
PNG
(CHEMBL106808)
Show SMILES CCOC(=O)Nc1nc(NC(C)CCCN(CC)CC)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1
Show InChI InChI=1S/C30H37N7O2/c1-5-37(6-2)20-14-15-21(4)31-27-26-28(35-29(34-27)36-30(38)39-7-3)33-25(23-18-12-9-13-19-23)24(32-26)22-16-10-8-11-17-22/h8-13,16-19,21H,5-7,14-15,20H2,1-4H3,(H2,31,33,34,35,36,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 3.81E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 4.40E+4n/an/an/an/an/an/a



THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...


US Patent US9169182 (2015)

More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359402
PNG
(CHEMBL1929427)
Show SMILES CCOC(=O)Nc1cc(NC(C)CCCN(CC)CC)c2nc(-c3ccccn3)c(nc2n1)-c1ccccn1
Show InChI InChI=1S/C29H36N8O2/c1-5-37(6-2)18-12-13-20(4)32-23-19-24(34-29(38)39-7-3)33-28-27(23)35-25(21-14-8-10-16-30-21)26(36-28)22-15-9-11-17-31-22/h8-11,14-17,19-20H,5-7,12-13,18H2,1-4H3,(H2,32,33,34,36,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.57E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359414
PNG
(CHEMBL1926726)
Show SMILES CCOC(=O)Nc1nc(NC(C)CCCN(CC)CC)c2N=C(C(Sc2n1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H38N6O2S/c1-5-36(6-2)20-14-15-21(4)31-27-25-28(34-29(33-27)35-30(37)38-7-3)39-26(23-18-12-9-13-19-23)24(32-25)22-16-10-8-11-17-22/h8-13,16-19,21,26H,5-7,14-15,20H2,1-4H3,(H2,31,33,34,35,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359415
PNG
(CHEMBL1926727)
Show SMILES CCOC(=O)Nc1nc(NCCCCN(CC)CC)c2N=C(C(Sc2n1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H36N6O2S/c1-4-35(5-2)20-14-13-19-30-26-24-27(33-28(32-26)34-29(36)37-6-3)38-25(22-17-11-8-12-18-22)23(31-24)21-15-9-7-10-16-21/h7-12,15-18,25H,4-6,13-14,19-20H2,1-3H3,(H2,30,32,33,34,36)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.62E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086197
PNG
(CHEMBL3425615)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)C1=CCCCC1
Show InChI InChI=1S/C26H29ClN4/c1-31(2)17-16-28-26-23-18-21(20-6-4-3-5-7-20)11-14-24(23)29-25(30-26)15-10-19-8-12-22(27)13-9-19/h6,8-15,18H,3-5,7,16-17H2,1-2H3,(H,28,29,30)/b15-10+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086109
PNG
(CHEMBL3425701)
Show SMILES [I-].C[N+](C)(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C25H26ClN4/c1-30(2,3)15-14-27-25-22-16-19-6-4-5-7-20(19)17-23(22)28-24(29-25)13-10-18-8-11-21(26)12-9-18/h4-13,16-17H,14-15H2,1-3H3,(H,27,28,29)/q+1/b13-10+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359405
PNG
(CHEMBL457349)
Show SMILES CCOC(=O)Nc1cc(NCCCCN(CC)CC)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1
Show InChI InChI=1S/C30H36N6O2/c1-4-36(5-2)20-14-13-19-31-24-21-25(33-30(37)38-6-3)32-29-28(24)34-26(22-15-9-7-10-16-22)27(35-29)23-17-11-8-12-18-23/h7-12,15-18,21H,4-6,13-14,19-20H2,1-3H3,(H2,31,32,33,35,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50359409
PNG
(CHEMBL1926721)
Show SMILES CCOC(=O)Nc1cc(NCCN(C)C)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1
Show InChI InChI=1S/C26H28N6O2/c1-4-34-26(33)29-21-17-20(27-15-16-32(2)3)24-25(28-21)31-23(19-13-9-6-10-14-19)22(30-24)18-11-7-5-8-12-18/h5-14,17H,4,15-16H2,1-3H3,(H2,27,28,29,31,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.46E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086199
PNG
(CHEMBL3425613)
Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)-c1ccc2ccccc2c1
Show InChI InChI=1S/C30H27ClN4/c1-35(2)18-17-32-30-27-20-25(24-11-10-22-5-3-4-6-23(22)19-24)12-15-28(27)33-29(34-30)16-9-21-7-13-26(31)14-8-21/h3-16,19-20H,17-18H2,1-2H3,(H,32,33,34)/b16-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 5.80E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Escherichia coli)
BDBM50086120
PNG
(CHEMBL3425697)
Show SMILES CN(C)CCCNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12
Show InChI InChI=1S/C25H25ClN4/c1-30(2)15-5-14-27-25-22-16-19-6-3-4-7-20(19)17-23(22)28-24(29-25)13-10-18-8-11-21(26)12-9-18/h3-4,6-13,16-17H,5,14-15H2,1-2H3,(H,27,28,29)/b13-10+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.50E+4n/an/an/an/an/an/a



University of California at Davis

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Staphylococcus aureus)
BDBM50439495
PNG
(CHEMBL2418095)
Show SMILES Oc1cc(O)c2Oc3cc(C\C=C(Cl)/Cc4cc(O)c(Oc5cc(C\C=C(Cl)/Cc2c1)c(O)cc5Cl)c(O)c4)c(O)cc3Cl
Show InChI InChI=1S/C32H24Cl4O8/c33-19-3-1-16-10-29(22(35)13-24(16)38)43-31-18(9-21(37)12-28(31)42)8-20(34)4-2-17-11-30(23(36)14-25(17)39)44-32-26(40)6-15(5-19)7-27(32)41/h3-4,6-7,9-14,37-42H,1-2,5,8H2/b19-3+,20-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 6.70E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...


Citation and Details
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Bacillus subtilis)
BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 100 total )  |  Next  |  Last  >>
Jump to: