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Found 30 hits Enz. Inhib. hit(s) with Target = 'Chorismate mutase (MTB CM)'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108084
PNG
(3-((5-nitrothiophen-2-yl)methylene)indolin-2-one (...)
Show SMILES [O-][N+](=O)c1ccc(\C=C2/C(=O)Nc3ccccc23)s1
Show InChI InChI=1S/C13H8N2O3S/c16-13-10(9-3-1-2-4-11(9)14-13)7-8-5-6-12(19-8)15(17)18/h1-7H,(H,14,16)/b10-7-
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n/an/a 930n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM22787
PNG
(1-acetyl-2,3-dihydro-1H-indole-2,3-dione | Acetyli...)
Show SMILES CC(=O)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C10H7NO3/c1-6(12)11-8-5-3-2-4-7(8)9(13)10(11)14/h2-5H,1H3
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n/an/a 990n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108083
PNG
(3-(4-nitrobenzylidene)indolin-2-one (Compound 24))
Show SMILES [O-][N+](=O)c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
Show InChI InChI=1S/C15H10N2O3/c18-15-13(12-3-1-2-4-14(12)16-15)9-10-5-7-11(8-6-10)17(19)20/h1-9H,(H,16,18)/b13-9-
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n/an/a 1.01E+3n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM11022
PNG
(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Show SMILES O=C1Nc2ccccc2C1=O
Show InChI InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)
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n/an/a 1.08E+3n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM10304
PNG
(1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...)
Show SMILES CN1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3
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n/an/a 1.96E+3n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50363851
PNG
(CHEMBL1945938)
Show SMILES Fc1cc2[nH]cc(-c3nc4ccccc4nc3Cl)c2cc1F
Show InChI InChI=1S/C16H8ClF2N3/c17-16-15(21-12-3-1-2-4-13(12)22-16)9-7-20-14-6-11(19)10(18)5-8(9)14/h1-7,20H
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n/an/a 1.97E+4n/an/an/an/an/an/a



University of Hyderabad Campus

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis chorismate mutase expressed in Escherichia coli BL21 assessed as conversion of chorismate to prephenate afte...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108065
PNG
(1‐ethylindole‐2,3‐dione (Compoun...)
Show SMILES CCN1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C10H9NO2/c1-2-11-8-6-4-3-5-7(8)9(12)10(11)13/h3-6H,2H2,1H3
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n/an/a 2.27E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM22793
PNG
(1‐phenylindole‐2,3‐dione (Compou...)
Show SMILES O=C1N(c2ccccc2C1=O)c1ccccc1
Show InChI InChI=1S/C14H9NO2/c16-13-11-8-4-5-9-12(11)15(14(13)17)10-6-2-1-3-7-10/h1-9H
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n/an/a 2.33E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108072
PNG
(1‐[(3Z)‐1‐acetyl‐2‐o...)
Show SMILES CC(=O)N1C(=O)C(=NC(=O)NN)c2ccccc12
Show InChI InChI=1S/C11H10N4O3/c1-6(16)15-8-5-3-2-4-7(8)9(10(15)17)13-11(18)14-12/h2-5H,12H2,1H3,(H,14,18)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108081
PNG
(5‐(piperidin‐1‐yl)‐1H̴...)
Show SMILES O=C1Nc2ccc(cc2C1=O)N1CCCCC1
Show InChI InChI=1S/C13H14N2O2/c16-12-10-8-9(15-6-2-1-3-7-15)4-5-11(10)14-13(12)17/h4-5,8H,1-3,6-7H2,(H,14,16,17)
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n/an/a 2.56E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108082
PNG
(5‐[4‐(furan‐2‐carbonyl)pip...)
Show SMILES O=C(N1CCN(CC1)c1ccc2NC(=O)C(=O)c2c1)c1ccco1
Show InChI InChI=1S/C17H15N3O4/c21-15-12-10-11(3-4-13(12)18-16(15)22)19-5-7-20(8-6-19)17(23)14-2-1-9-24-14/h1-4,9-10H,5-8H2,(H,18,21,22)
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n/an/a 2.88E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108071
PNG
(1‐[(3Z)‐1‐acetyl‐2‐o...)
Show SMILES CC(=O)n1c(O)c(NC(=S)N=N)c2ccccc12
Show InChI InChI=1S/C11H10N4O2S/c1-6(16)15-8-5-3-2-4-7(8)9(10(15)17)13-11(18)14-12/h2-5,12,17H,1H3,(H,13,18)
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n/an/a 3.05E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108079
PNG
(5‐(4‐methylpiperazin‐1‐yl)...)
Show SMILES CN1CCN(CC1)c1ccc2NC(=O)C(=O)c2c1
Show InChI InChI=1S/C13H15N3O2/c1-15-4-6-16(7-5-15)9-2-3-11-10(8-9)12(17)13(18)14-11/h2-3,8H,4-7H2,1H3,(H,14,17,18)
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n/an/a 3.19E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108077
PNG
(5‐(2,5‐dimethylphenyl)‐1H‐...)
Show SMILES Cc1ccc(C)c(c1)-c1ccc2NC(=O)C(=O)c2c1
Show InChI InChI=1S/C16H13NO2/c1-9-3-4-10(2)12(7-9)11-5-6-14-13(8-11)15(18)16(19)17-14/h3-8H,1-2H3,(H,17,18,19)
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n/an/a 3.65E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50334290
PNG
(5‐phenyl‐1H‐indole‐2,3R...)
Show SMILES O=C1Nc2ccc(cc2C1=O)-c1ccccc1
Show InChI InChI=1S/C14H9NO2/c16-13-11-8-10(9-4-2-1-3-5-9)6-7-12(11)15-14(13)17/h1-8H,(H,15,16,17)
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n/an/a 3.71E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108078
PNG
(5‐(piperazin‐1‐yl)‐1H̴...)
Show SMILES O=C1Nc2ccc(cc2C1=O)N1CCNCC1
Show InChI InChI=1S/C12H13N3O2/c16-11-9-7-8(15-5-3-13-4-6-15)1-2-10(9)14-12(11)17/h1-2,7,13H,3-6H2,(H,14,16,17)
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n/an/a 3.99E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108068
PNG
(1‐(2,2‐dimethylpropanoyl)indole‐...)
Show SMILES CC(C)(C)C(=O)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C13H13NO3/c1-13(2,3)12(17)14-9-7-5-4-6-8(9)10(15)11(14)16/h4-7H,1-3H3
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n/an/a 4.10E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108070
PNG
(3‐amino‐1‐[(3Z)‐2‐ox...)
Show SMILES NNC(=O)\N=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C9H8N4O2/c10-13-9(15)12-7-5-3-1-2-4-6(5)11-8(7)14/h1-4H,10H2,(H2,11,12,13,14,15)
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n/an/a 5.41E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108080
PNG
(5‐{4‐[3‐(trifluoromethyl)phenyl]...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)c1ccc2NC(=O)C(=O)c2c1
Show InChI InChI=1S/C19H16F3N3O2/c20-19(21,22)12-2-1-3-13(10-12)24-6-8-25(9-7-24)14-4-5-16-15(11-14)17(26)18(27)23-16/h1-5,10-11H,6-9H2,(H,23,26,27)
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n/an/a 5.57E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108069
PNG
(3‐amino‐1‐[(3Z)‐2‐ox...)
Show SMILES NNC(=S)N=C1C(=O)Nc2ccccc12
Show InChI InChI=1S/C9H8N4OS/c10-13-9(15)12-7-5-3-1-2-4-6(5)11-8(7)14/h1-4H,10H2,(H2,11,12,13,14,15)
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n/an/a 6.69E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108066
PNG
(1‐isopropylindole‐2,3‐dione (Com...)
Show SMILES CC(C)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C11H11NO2/c1-7(2)12-9-6-4-3-5-8(9)10(13)11(12)14/h3-7H,1-2H3
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n/an/a 7.51E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108076
PNG
(5‐(2,3‐dichlorophenyl)‐1H‐...)
Show SMILES Clc1cccc(c1Cl)-c1ccc2NC(=O)C(=O)c2c1
Show InChI InChI=1S/C14H7Cl2NO2/c15-10-3-1-2-8(12(10)16)7-4-5-11-9(6-7)13(18)14(19)17-11/h1-6H,(H,17,18,19)
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n/an/a 9.57E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108067
PNG
(1‐(prop‐2‐en‐1‐yl)in...)
Show SMILES C=CCN1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C11H9NO2/c1-2-7-12-9-6-4-3-5-8(9)10(13)11(12)14/h2-6H,1,7H2
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n/an/a 9.66E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108075
PNG
((3Z)‐3‐(hydroxyimino)‐1H‐i...)
Show SMILES O=NC1C(=O)Nc2ccccc12
Show InChI InChI=1S/C8H6N2O2/c11-8-7(10-12)5-3-1-2-4-6(5)9-8/h1-4,7H,(H,9,11)
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n/an/a 9.81E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108073
PNG
((3Z)‐3‐[(5‐nitro‐1,3‐...)
Show SMILES [O-][N+](=O)c1cnc(\N=C2/C(=O)Nc3ccccc23)s1
Show InChI InChI=1S/C11H6N4O3S/c16-10-9(6-3-1-2-4-7(6)13-10)14-11-12-5-8(19-11)15(17)18/h1-5H,(H,12,13,14,16)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM108074
PNG
((3Z)‐3‐[(6‐nitro‐1,3‐...)
Show SMILES [O-][N+](=O)c1ccc2nc(\N=C3/C(=O)Nc4ccccc34)sc2c1
Show InChI InChI=1S/C15H8N4O3S/c20-14-13(9-3-1-2-4-10(9)16-14)18-15-17-11-6-5-8(19(21)22)7-12(11)23-15/h1-7H,(H,16,17,18,20)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India



Assay Description
The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50209967
PNG
(4-[2-(3,4-dimethoxy-phenyl)-ethylamino]-3-nitro-5-...)
Show SMILES COc1ccc(CCNc2c(cc(cc2S(N)(=O)=O)C(O)=O)[N+]([O-])=O)cc1OC
Show InChI InChI=1S/C17H19N3O8S/c1-27-13-4-3-10(7-14(13)28-2)5-6-19-16-12(20(23)24)8-11(17(21)22)9-15(16)29(18,25)26/h3-4,7-9,19H,5-6H2,1-2H3,(H,21,22)(H2,18,25,26)
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5.70E+3n/an/an/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of chorismate mutase in Mycobacterium tuberculosis H37Rv strain


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50209968
PNG
((Z)-2-(4-chlorophenyl)-3-(4,5-dimethoxy-2-nitrophe...)
Show SMILES COc1cc(\C=C(/C(O)=O)c2ccc(Cl)cc2)c(cc1OC)[N+]([O-])=O
Show InChI InChI=1S/C17H14ClNO6/c1-24-15-8-11(14(19(22)23)9-16(15)25-2)7-13(17(20)21)10-3-5-12(18)6-4-10/h3-9H,1-2H3,(H,20,21)/b13-7-
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1.77E+4n/an/an/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of chorismate mutase in Mycobacterium tuberculosis H37Rv strain


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50209969
PNG
(2-(3-(tert-butoxycarbonyl)-2-phenylthiazolidine-4-...)
Show SMILES CC(C)CC(NC(=O)C1CSC(N1C(=O)OC(C)(C)C)c1ccccc1)C(O)=O
Show InChI InChI=1S/C21H30N2O5S/c1-13(2)11-15(19(25)26)22-17(24)16-12-29-18(14-9-7-6-8-10-14)23(16)20(27)28-21(3,4)5/h6-10,13,15-16,18H,11-12H2,1-5H3,(H,22,24)(H,25,26)
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2.11E+4n/an/an/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of chorismate mutase in Mycobacterium tuberculosis H37Rv strain


Citation and Details
More data for this
Ligand-Target Pair
Chorismate mutase (MTB CM)


(Mycobacterium tuberculosis H37Rv)
BDBM50209966
PNG
(CHEMBL242816 | methyl 4-(methylamino)-3-nitrobenzo...)
Show SMILES CNc1ccc(cc1[N+]([O-])=O)C(=O)OC
Show InChI InChI=1S/C9H10N2O4/c1-10-7-4-3-6(9(12)15-2)5-8(7)11(13)14/h3-5,10H,1-2H3
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2.88E+4n/an/an/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of chorismate mutase in Mycobacterium tuberculosis H37Rv strain


Citation and Details
More data for this
Ligand-Target Pair