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Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with Target = 'CpG DNA methylase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50059989
PNG
((1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-he...)
Show SMILES Oc1ccc(C=CC(=O)CC(=O)C=Cc2ccc(O)cc2)cc1
Show InChI InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2
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n/an/a 30n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of Spiroplasma sp. MQ-1 M.SssI


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50067040
PNG
(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O
Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3
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n/an/a 30n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of Spiroplasma sp. MQ-1 M.SssI


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50163744
PNG
((1E,4Z,6E)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl...)
Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)cc2)ccc1O
Show InChI InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3
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n/an/a 30n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of Spiroplasma sp. MQ-1 M.SssI


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50180789
PNG
(1,2-bis(7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-y...)
Show SMILES Cc1ccn2c(CCc3nnc4cc(C)ccn34)nnc2c1
Show InChI InChI=1S/C16H16N6/c1-11-5-7-21-13(17-19-15(21)9-11)3-4-14-18-20-16-10-12(2)6-8-22(14)16/h5-10H,3-4H2,1-2H3
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n/an/a 400n/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant CpG methylase M.SssI


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50180790
PNG
(2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)prop...)
Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)
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n/an/a 600n/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant CpG methylase M.SssI


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389487
PNG
(CHEMBL2063048)
Show SMILES O=C1NCNC(NCc2ccco2)=N1
Show InChI InChI=1S/C8H10N4O2/c13-8-11-5-10-7(12-8)9-4-6-2-1-3-14-6/h1-3H,4-5H2,(H3,9,10,11,12,13)
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n/an/a 2.73E+3n/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Spiroplasma sp. MQ1 SssI methyltransferase-mediated DNA cytosine methylation using pUC18 as substrate and [3H]CH3-SAM measured up to 10...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50384789
PNG
(CHEMBL2037378 | Laccaic acid A (LCA))
Show SMILES CC(=O)NCCc1ccc(O)c(c1)-c1c(O)c(O)c2C(=O)c3cc(O)c(C(O)=O)c(C(O)=O)c3C(=O)c2c1O
Show InChI InChI=1S/C26H19NO12/c1-8(28)27-5-4-9-2-3-12(29)10(6-9)15-22(33)19-18(24(35)23(15)34)20(31)11-7-13(30)16(25(36)37)17(26(38)39)14(11)21(19)32/h2-3,6-7,29-30,33-35H,4-5H2,1H3,(H,27,28)(H,36,37)(H,38,39)
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n/an/a 5.36E+4n/an/an/an/an/an/a



University of Iowa



Assay Description
Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...


J Biol Chem 288: 23858-67 (2013)

More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50070942
PNG
((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Show SMILES Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
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28n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389497
PNG
(CHEMBL1564869)
Show SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1
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230n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389487
PNG
(CHEMBL2063048)
Show SMILES O=C1NCNC(NCc2ccco2)=N1
Show InChI InChI=1S/C8H10N4O2/c13-8-11-5-10-7(12-8)9-4-6-2-1-3-14-6/h1-3H,4-5H2,(H3,9,10,11,12,13)
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700n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389488
PNG
(CHEMBL2063060)
Show SMILES Cc1cnc(=O)[nH]c1NCc1ccccc1
Show InChI InChI=1S/C12H13N3O/c1-9-7-14-12(16)15-11(9)13-8-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H2,13,14,15,16)
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3.60E+3n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389495
PNG
(CHEMBL2063052)
Show SMILES O=c1nccc(NCc2ccccc2)[nH]1
Show InChI InChI=1S/C11H11N3O/c15-11-12-7-6-10(14-11)13-8-9-4-2-1-3-5-9/h1-7H,8H2,(H2,12,13,14,15)
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1.00E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389498
PNG
(CHEMBL2063050)
Show SMILES Cc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C10H11N3O2/c1-7-5-12-10(14)13-9(7)11-6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H2,11,12,13,14)
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1.50E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389489
PNG
(CHEMBL2063059)
Show SMILES O=C1NCNC(NCc2ccccc2)=N1
Show InChI InChI=1S/C10H12N4O/c15-10-13-7-12-9(14-10)11-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H3,11,12,13,14,15)
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2.00E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389481
PNG
(CHEMBL2063056)
Show SMILES CC(=O)OCc1cnc(=O)[nH]c1NCc1ccccc1
Show InChI InChI=1S/C14H15N3O3/c1-10(18)20-9-12-8-16-14(19)17-13(12)15-7-11-5-3-2-4-6-11/h2-6,8H,7,9H2,1H3,(H2,15,16,17,19)
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2.30E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389494
PNG
(CHEMBL2063053)
Show SMILES Cc1ccc(CNc2ccnc(=O)[nH]2)cc1
Show InChI InChI=1S/C12H13N3O/c1-9-2-4-10(5-3-9)8-14-11-6-7-13-12(16)15-11/h2-7H,8H2,1H3,(H2,13,14,15,16)
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2.60E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389491
PNG
(CHEMBL2063057)
Show SMILES OS(=O)(=O)Cc1cnc(=O)[nH]c1NCc1ccccc1
Show InChI InChI=1S/C12H13N3O4S/c16-12-14-7-10(8-20(17,18)19)11(15-12)13-6-9-4-2-1-3-5-9/h1-5,7H,6,8H2,(H,17,18,19)(H2,13,14,15,16)
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3.30E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389490
PNG
(CHEMBL2063058)
Show SMILES O=Cc1cnc(=O)[nH]c1NCc1ccccc1
Show InChI InChI=1S/C12H11N3O2/c16-8-10-7-14-12(17)15-11(10)13-6-9-4-2-1-3-5-9/h1-5,7-8H,6H2,(H2,13,14,15,17)
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3.50E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389503
PNG
(CHEMBL2063044)
Show SMILES CC(=O)OCc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C12H13N3O4/c1-8(16)19-7-9-5-14-12(17)15-11(9)13-6-10-3-2-4-18-10/h2-5H,6-7H2,1H3,(H2,13,14,15,17)
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5.00E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389482
PNG
(CHEMBL1699292)
Show SMILES O=c1nccc(NCc2ccco2)[nH]1
Show InChI InChI=1S/C9H9N3O2/c13-9-10-4-3-8(12-9)11-6-7-2-1-5-14-7/h1-5H,6H2,(H2,10,11,12,13)
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7.00E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389501
PNG
(CHEMBL2063046)
Show SMILES O=Cc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C10H9N3O3/c14-6-7-4-12-10(15)13-9(7)11-5-8-2-1-3-16-8/h1-4,6H,5H2,(H2,11,12,13,15)
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8.30E+4n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389502
PNG
(CHEMBL2063045)
Show SMILES OS(=O)(=O)Cc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C10H11N3O5S/c14-10-12-4-7(6-19(15,16)17)9(13-10)11-5-8-2-1-3-18-8/h1-4H,5-6H2,(H,15,16,17)(H2,11,12,13,14)
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1.12E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389492
PNG
(CHEMBL2063055)
Show SMILES OCc1cnc(=O)[nH]c1NCc1ccccc1
Show InChI InChI=1S/C12H13N3O2/c16-8-10-7-14-12(17)15-11(10)13-6-9-4-2-1-3-5-9/h1-5,7,16H,6,8H2,(H2,13,14,15,17)
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1.35E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389505
PNG
(CHEMBL2063041)
Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(NCc2ccco2)nc1=O
Show InChI InChI=1S/C14H17N3O5/c18-8-11-10(19)6-13(22-11)17-4-3-12(16-14(17)20)15-7-9-2-1-5-21-9/h1-5,10-11,13,18-19H,6-8H2,(H,15,16,20)/t10-,11+,13+/m0/s1
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1.70E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389499
PNG
(CHEMBL2063049)
Show SMILES Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)nc1NCc1ccco1
Show InChI InChI=1S/C15H19N3O5/c1-9-7-18(13-5-11(20)12(8-19)23-13)15(21)17-14(9)16-6-10-3-2-4-22-10/h2-4,7,11-13,19-20H,5-6,8H2,1H3,(H,16,17,21)/t11-,12+,13+/m0/s1
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2.50E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389493
PNG
(CHEMBL2063054)
Show SMILES O=c1nccc(NCc2cccnc2)[nH]1
Show InChI InChI=1S/C10H10N4O/c15-10-12-5-3-9(14-10)13-7-8-2-1-4-11-6-8/h1-6H,7H2,(H2,12,13,14,15)
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4.00E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389504
PNG
(CHEMBL2063043)
Show SMILES OCc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C10H11N3O3/c14-6-7-4-12-10(15)13-9(7)11-5-8-2-1-3-16-8/h1-4,14H,5-6H2,(H2,11,12,13,15)
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4.40E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389496
PNG
(CHEMBL472604)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccnc(=O)[nH]1
Show InChI InChI=1S/C11H11N3O3S/c1-8-2-4-9(5-3-8)18(16,17)14-10-6-7-12-11(15)13-10/h2-7H,1H3,(H2,12,13,14,15)
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5.50E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389509
PNG
(CHEMBL2063042)
Show SMILES OCc1ccc(CNc2ccnc(=O)[nH]2)o1
Show InChI InChI=1S/C10H11N3O3/c14-6-8-2-1-7(16-8)5-12-9-3-4-11-10(15)13-9/h1-4,14H,5-6H2,(H2,11,12,13,15)
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7.00E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389506
PNG
(CHEMBL2063064)
Show SMILES CCCC=Nc1ccnc(=O)[nH]1
Show InChI InChI=1S/C8H11N3O/c1-2-3-5-9-7-4-6-10-8(12)11-7/h4-6H,2-3H2,1H3,(H,10,11,12)
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8.00E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Uncompetitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Cornish-Bowden's plot analysi...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389500
PNG
(CHEMBL2063047)
Show SMILES CCCCNCc1cnc(=O)[nH]c1NCc1ccco1
Show InChI InChI=1S/C14H20N4O2/c1-2-3-6-15-8-11-9-17-14(19)18-13(11)16-10-12-5-4-7-20-12/h4-5,7,9,15H,2-3,6,8,10H2,1H3,(H2,16,17,18,19)
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9.60E+5n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389485
PNG
(CHEMBL2063066)
Show SMILES CCCCNc1ccnc(=O)[nH]1
Show InChI InChI=1S/C8H13N3O/c1-2-3-5-9-7-4-6-10-8(12)11-7/h4,6H,2-3,5H2,1H3,(H2,9,10,11,12)
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1.00E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Uncompetitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Cornish-Bowden's plot analysi...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389483
PNG
(CHEMBL2063063)
Show SMILES CCC=Nc1ccnc(=O)[nH]1
Show InChI InChI=1S/C7H9N3O/c1-2-4-8-6-3-5-9-7(11)10-6/h3-5H,2H2,1H3,(H,9,10,11)
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3.40E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Uncompetitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Cornish-Bowden's plot analysi...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389508
PNG
(CHEMBL1230389)
Show SMILES Nc1ncnc(=O)[nH]1
Show InChI InChI=1S/C3H4N4O/c4-2-5-1-6-3(8)7-2/h1H,(H3,4,5,6,7,8)
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5.50E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389486
PNG
(CHEMBL2063062)
Show SMILES CC=Nc1ccnc(=O)[nH]1
Show InChI InChI=1S/C6H7N3O/c1-2-7-5-3-4-8-6(10)9-5/h2-4H,1H3,(H,8,9,10)
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5.60E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Uncompetitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Cornish-Bowden's plot analysi...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389484
PNG
(CHEMBL2063065)
Show SMILES CCNc1cc[nH]c(=O)n1
Show InChI InChI=1S/C6H9N3O/c1-2-7-5-3-4-8-6(10)9-5/h3-4H,2H2,1H3,(H2,7,8,9,10)
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6.00E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Uncompetitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Cornish-Bowden's plot analysi...


Citation and Details
More data for this
Ligand-Target Pair
M.SssI methyltransferase


(Spiroplasma monobiae strain MQ-1)
BDBM50389507
PNG
(CHEMBL2063051)
Show SMILES [O-][N+](=O)c1ccccc1CNc1ccnc(=O)[nH]1
Show InChI InChI=1S/C11H10N4O3/c16-11-12-6-5-10(14-11)13-7-8-3-1-2-4-9(8)15(17)18/h1-6H,7H2,(H2,12,13,14,16)
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6.40E+6n/an/an/an/an/an/an/an/a



Polish Academy of Sciences

Curated by ChEMBL


Assay Description
Non-competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysis


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More data for this
Ligand-Target Pair