Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lecithin-cholesterol acyltransferase (LCAT)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lecithin-cholesterol acyltransferase (LCAT) (Homo sapiens (Human))	BDBM92615 (Difluoroketone phospholipid analogue, 3) Show SMILES CCCCCCCCCCCCCCCCC(=O)C(F)(F)C(COCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C Show InChI InChI=1S/C34H68F2NO6P/c1-6-8-10-12-14-15-16-17-18-19-20-21-22-24-26-33(38)34(35,36)32(30-41-28-25-23-13-11-9-7-2)31-43-44(39,40)42-29-27-37(3,4)5/h32H,6-31H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	4
Dalhousie University					Assay Description The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...				J Biol Chem 264: 1963-1967 (1989) BindingDB Entry DOI: 10.7270/Q2M0441T
					More data for this Ligand-Target Pair
Lecithin-cholesterol acyltransferase (LCAT) (Homo sapiens (Human))	BDBM92616 (Difluoroketone phospholipid analogue, 4) Show SMILES CCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)CC(=O)C(F)(F)CCCCCC Show InChI InChI=1S/C25H48F2NO7P/c1-6-8-10-12-13-15-24(30)33-20-22(19-23(29)25(26,27)16-14-11-9-7-2)21-35-36(31,32)34-18-17-28(3,4)5/h22H,6-21H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	4
Dalhousie University					Assay Description The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...				J Biol Chem 264: 1963-1967 (1989) BindingDB Entry DOI: 10.7270/Q2M0441T
					More data for this Ligand-Target Pair
Lecithin-cholesterol acyltransferase (LCAT) (Homo sapiens (Human))	BDBM92614 (Difluoroketone phospholipid analogue, 2) Show SMILES CCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)C(F)(F)C(=O)CCCCCCC Show InChI InChI=1S/C25H50F2NO6P/c1-6-8-10-12-14-16-19-32-21-23(22-34-35(30,31)33-20-18-28(3,4)5)25(26,27)24(29)17-15-13-11-9-7-2/h23H,6-22H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	4
Dalhousie University					Assay Description The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...				J Biol Chem 264: 1963-1967 (1989) BindingDB Entry DOI: 10.7270/Q2M0441T
					More data for this Ligand-Target Pair
Lecithin-cholesterol acyltransferase (LCAT) (Homo sapiens (Human))	BDBM92613 (Difluoroketone phospholipid analogue, 1) Show SMILES CCCCCCCC(=O)C(F)(F)CCOP([O-])(=O)OCC[N+](C)(C)C Show InChI InChI=1S/C16H32F2NO5P/c1-5-6-7-8-9-10-15(20)16(17,18)11-13-23-25(21,22)24-14-12-19(2,3)4/h5-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	7.5	4
Dalhousie University					Assay Description The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...				J Biol Chem 264: 1963-1967 (1989) BindingDB Entry DOI: 10.7270/Q2M0441T
					More data for this Ligand-Target Pair