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Found 188 hits Enz. Inhib. hit(s) with Target = 'Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440614
PNG
(CHEMBL2426364)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
Show InChI InChI=1S/C32H43N5O2/c38-31(36-20-12-27(13-21-36)34-16-4-5-17-34)25-10-11-29(30(24-25)33-26-8-2-1-3-9-26)32(39)37-22-14-28(15-23-37)35-18-6-7-19-35/h1-3,8-11,24,27-28,33H,4-7,12-23H2
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n/an/a 24n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496581
PNG
(CHEMBL3134130)
Show SMILES Clc1cc(ccc1CCN1CCCC1)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C21H32ClN3/c22-21-17-20(6-5-18(21)7-14-23-10-1-2-11-23)25-15-8-19(9-16-25)24-12-3-4-13-24/h5-6,17,19H,1-4,7-16H2
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University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440613
PNG
(CHEMBL2426365)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(NCc2ccccc2)c1
Show InChI InChI=1S/C33H45N5O2/c39-32(37-20-12-28(13-21-37)35-16-4-5-17-35)27-10-11-30(31(24-27)34-25-26-8-2-1-3-9-26)33(40)38-22-14-29(15-23-38)36-18-6-7-19-36/h1-3,8-11,24,28-29,34H,4-7,12-23,25H2
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n/an/a 39n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440563
PNG
(CHEMBL2426360)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c2ccccc12
Show InChI InChI=1S/C30H40N4O2/c35-29(33-19-11-23(12-20-33)31-15-3-4-16-31)27-9-10-28(26-8-2-1-7-25(26)27)30(36)34-21-13-24(14-22-34)32-17-5-6-18-32/h1-2,7-10,23-24H,3-6,11-22H2
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n/an/a 43n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440612
PNG
(CHEMBL2426366)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Cc2ccccc2)c1
Show InChI InChI=1S/C33H44N4O2/c38-32(36-20-12-29(13-21-36)34-16-4-5-17-34)27-10-11-31(28(25-27)24-26-8-2-1-3-9-26)33(39)37-22-14-30(15-23-37)35-18-6-7-19-35/h1-3,8-11,25,29-30H,4-7,12-24H2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496591
PNG
(CHEMBL3134144)
Show SMILES C(Cc1ccc(cc1)N1CCC(CC1)N1CCCC1)N1CCC1
Show InChI InChI=1S/C20H31N3/c1-2-14-22(13-1)20-9-16-23(17-10-20)19-6-4-18(5-7-19)8-15-21-11-3-12-21/h4-7,20H,1-3,8-17H2
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n/an/a 48n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440603
PNG
(CHEMBL2426498)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-17-9-23(10-18-29)27-13-1-2-14-27)21-5-7-22(8-6-21)26(32)30-19-11-24(12-20-30)28-15-3-4-16-28/h5-8,23-24H,1-4,9-20H2
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n/an/a 48n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440614
PNG
(CHEMBL2426364)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
Show InChI InChI=1S/C32H43N5O2/c38-31(36-20-12-27(13-21-36)34-16-4-5-17-34)25-10-11-29(30(24-25)33-26-8-2-1-3-9-26)32(39)37-22-14-28(15-23-37)35-18-6-7-19-35/h1-3,8-11,24,27-28,33H,4-7,12-23H2
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n/an/a 49n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440613
PNG
(CHEMBL2426365)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(NCc2ccccc2)c1
Show InChI InChI=1S/C33H45N5O2/c39-32(37-20-12-28(13-21-37)35-16-4-5-17-35)27-10-11-30(31(24-27)34-25-26-8-2-1-3-9-26)33(40)38-22-14-29(15-23-38)36-18-6-7-19-36/h1-3,8-11,24,28-29,34H,4-7,12-23,25H2
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n/an/a 50n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440612
PNG
(CHEMBL2426366)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Cc2ccccc2)c1
Show InChI InChI=1S/C33H44N4O2/c38-32(36-20-12-29(13-21-36)34-16-4-5-17-34)27-10-11-31(28(25-27)24-26-8-2-1-3-9-26)33(39)37-22-14-30(15-23-37)35-18-6-7-19-35/h1-3,8-11,25,29-30H,4-7,12-24H2
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n/an/a 51n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440611
PNG
(CHEMBL2426367)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Oc2ccccc2)c1
Show InChI InChI=1S/C32H42N4O3/c37-31(35-20-12-26(13-21-35)33-16-4-5-17-33)25-10-11-29(30(24-25)39-28-8-2-1-3-9-28)32(38)36-22-14-27(15-23-36)34-18-6-7-19-34/h1-3,8-11,24,26-27H,4-7,12-23H2
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n/an/a 53n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440611
PNG
(CHEMBL2426367)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Oc2ccccc2)c1
Show InChI InChI=1S/C32H42N4O3/c37-31(35-20-12-26(13-21-35)33-16-4-5-17-33)25-10-11-29(30(24-25)39-28-8-2-1-3-9-28)32(38)36-22-14-27(15-23-36)34-18-6-7-19-34/h1-3,8-11,24,26-27H,4-7,12-23H2
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n/an/a 58n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496584
PNG
(CHEMBL3134146)
Show SMILES OCC1(CO)CN(CCc2ccc(cc2)N2CCC(CC2)N2CCCC2)C1
Show InChI InChI=1S/C22H35N3O2/c26-17-22(18-27)15-23(16-22)12-7-19-3-5-20(6-4-19)25-13-8-21(9-14-25)24-10-1-2-11-24/h3-6,21,26-27H,1-2,7-18H2
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University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440569
PNG
(CHEMBL2424678)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(nc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c31-24(29-15-7-21(8-16-29)27-11-1-2-12-27)20-5-6-23(26-19-20)25(32)30-17-9-22(10-18-30)28-13-3-4-14-28/h5-6,19,21-22H,1-4,7-18H2
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n/an/a 61n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440610
PNG
(CHEMBL2426368)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(c1)-c1ccccc1
Show InChI InChI=1S/C32H42N4O2/c37-31(35-20-12-27(13-21-35)33-16-4-5-17-33)26-10-11-29(30(24-26)25-8-2-1-3-9-25)32(38)36-22-14-28(15-23-36)34-18-6-7-19-34/h1-3,8-11,24,27-28H,4-7,12-23H2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496593
PNG
(CHEMBL3134131)
Show SMILES C(Cc1ccc(cc1)N1CCC(CC1)N1CCCC1)N1CCCC1
Show InChI InChI=1S/C21H33N3/c1-2-13-22(12-1)16-9-19-5-7-20(8-6-19)24-17-10-21(11-18-24)23-14-3-4-15-23/h5-8,21H,1-4,9-18H2
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n/an/a 62n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440614
PNG
(CHEMBL2426364)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
Show InChI InChI=1S/C32H43N5O2/c38-31(36-20-12-27(13-21-36)34-16-4-5-17-34)25-10-11-29(30(24-25)33-26-8-2-1-3-9-26)32(39)37-22-14-28(15-23-37)35-18-6-7-19-35/h1-3,8-11,24,27-28,33H,4-7,12-23H2
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n/an/a 64n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440610
PNG
(CHEMBL2426368)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(c1)-c1ccccc1
Show InChI InChI=1S/C32H42N4O2/c37-31(35-20-12-27(13-21-35)33-16-4-5-17-33)26-10-11-29(30(24-26)25-8-2-1-3-9-25)32(38)36-22-14-28(15-23-36)34-18-6-7-19-34/h1-3,8-11,24,27-28H,4-7,12-23H2
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n/an/a 66n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440560
PNG
(CHEMBL2426363)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(s1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2S/c29-23(27-15-7-19(8-16-27)25-11-1-2-12-25)21-5-6-22(31-21)24(30)28-17-9-20(10-18-28)26-13-3-4-14-26/h5-6,19-20H,1-4,7-18H2
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n/an/a 68n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496596
PNG
(CHEMBL3134134)
Show SMILES C(CN1CCCC1)Cc1ccc(cc1)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C22H35N3/c1-2-14-23(13-1)15-5-6-20-7-9-21(10-8-20)25-18-11-22(12-19-25)24-16-3-4-17-24/h7-10,22H,1-6,11-19H2
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n/an/a 70n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440603
PNG
(CHEMBL2426498)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H38N4O2/c31-25(29-17-9-23(10-18-29)27-13-1-2-14-27)21-5-7-22(8-6-21)26(32)30-19-11-24(12-20-30)28-15-3-4-16-28/h5-8,23-24H,1-4,9-20H2
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n/an/a 71n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440563
PNG
(CHEMBL2426360)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c2ccccc12
Show InChI InChI=1S/C30H40N4O2/c35-29(33-19-11-23(12-20-33)31-15-3-4-16-31)27-9-10-28(26-8-2-1-7-25(26)27)30(36)34-21-13-24(14-22-34)32-17-5-6-18-32/h1-2,7-10,23-24H,3-6,11-22H2
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n/an/a 72n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440568
PNG
(CHEMBL2426476)
Show SMILES Brc1cc(ccc1C(=O)N1CCC(CC1)N1CCCC1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H37BrN4O2/c27-24-19-20(25(32)30-15-7-21(8-16-30)28-11-1-2-12-28)5-6-23(24)26(33)31-17-9-22(10-18-31)29-13-3-4-14-29/h5-6,19,21-22H,1-4,7-18H2
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n/an/a 74n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440585
PNG
(CHEMBL2426496)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCCC(CC1)N1CCCC1
Show InChI InChI=1/C27H40N4O2/c32-26(30-18-5-6-24(11-19-30)28-14-1-2-15-28)22-7-9-23(10-8-22)27(33)31-20-12-25(13-21-31)29-16-3-4-17-29/h7-10,24-25H,1-6,11-21H2
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n/an/a 74n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496589
PNG
(CHEMBL3134126)
Show SMILES C(Cc1ccc(cc1)N1CCC(CC1)N1CCCC1)N1CCCCC1
Show InChI InChI=1S/C22H35N3/c1-2-13-23(14-3-1)17-10-20-6-8-21(9-7-20)25-18-11-22(12-19-25)24-15-4-5-16-24/h6-9,22H,1-5,10-19H2
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n/an/a 80n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440592
PNG
(CHEMBL2426489)
Show SMILES C[N+]1(CCCC1)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C27H41N4O2/c1-31(20-4-5-21-31)25-12-18-30(19-13-25)27(33)23-8-6-22(7-9-23)26(32)29-16-10-24(11-17-29)28-14-2-3-15-28/h6-9,24-25H,2-5,10-21H2,1H3/q+1
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n/an/a 81n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440567
PNG
(CHEMBL2426477)
Show SMILES [O-][N+](=O)c1cc(ccc1C(=O)N1CCC(CC1)N1CCCC1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H37N5O4/c32-25(29-15-7-21(8-16-29)27-11-1-2-12-27)20-5-6-23(24(19-20)31(34)35)26(33)30-17-9-22(10-18-30)28-13-3-4-14-28/h5-6,19,21-22H,1-4,7-18H2
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n/an/a 88n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440591
PNG
(CHEMBL2426490)
Show SMILES O=C(N1CCC(CC1)C1CCCN1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1/C26H38N4O2/c31-25(29-16-9-20(10-17-29)24-4-3-13-27-24)21-5-7-22(8-6-21)26(32)30-18-11-23(12-19-30)28-14-1-2-15-28/h5-8,20,23-24,27H,1-4,9-19H2
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n/an/a 92n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440586
PNG
(CHEMBL2426495)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CC2CCC(C1)C2N1CCCC1
Show InChI InChI=1/C28H40N4O2/c33-27(31-17-11-25(12-18-31)29-13-1-2-14-29)21-5-7-22(8-6-21)28(34)32-19-23-9-10-24(20-32)26(23)30-15-3-4-16-30/h5-8,23-26H,1-4,9-20H2
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n/an/a 92n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440585
PNG
(CHEMBL2426496)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCCC(CC1)N1CCCC1
Show InChI InChI=1/C27H40N4O2/c32-26(30-18-5-6-24(11-19-30)28-14-1-2-15-28)22-7-9-23(10-8-22)27(33)31-20-12-25(13-21-31)29-16-3-4-17-29/h7-10,24-25H,1-6,11-21H2
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n/an/a 96n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440560
PNG
(CHEMBL2426363)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(s1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C24H36N4O2S/c29-23(27-15-7-19(8-16-27)25-11-1-2-12-25)21-5-6-22(31-21)24(30)28-17-9-20(10-18-28)26-13-3-4-14-26/h5-6,19-20H,1-4,7-18H2
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n/an/a 96n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440600
PNG
(CHEMBL2426481)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H38N4O3S/c30-25(28-17-9-22(10-18-28)26-13-1-2-14-26)21-5-7-24(8-6-21)33(31,32)29-19-11-23(12-20-29)27-15-3-4-16-27/h5-8,22-23H,1-4,9-20H2
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n/an/a 97n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440600
PNG
(CHEMBL2426481)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H38N4O3S/c30-25(28-17-9-22(10-18-28)26-13-1-2-14-26)21-5-7-24(8-6-21)33(31,32)29-19-11-23(12-20-29)27-15-3-4-16-27/h5-8,22-23H,1-4,9-20H2
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n/an/a 99n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496583
PNG
(CHEMBL3134125)
Show SMILES C(Cc1ccc(cc1)N1CCC(CC1)N1CCCC1)N1CCCCCC1
Show InChI InChI=1S/C23H37N3/c1-2-4-15-24(14-3-1)18-11-21-7-9-22(10-8-21)26-19-12-23(13-20-26)25-16-5-6-17-25/h7-10,23H,1-6,11-20H2
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n/an/a 100n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440569
PNG
(CHEMBL2424678)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(nc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C25H37N5O2/c31-24(29-15-7-21(8-16-29)27-11-1-2-12-27)20-5-6-23(26-19-20)25(32)30-17-9-22(10-18-30)28-13-3-4-14-28/h5-6,19,21-22H,1-4,7-18H2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440576
PNG
(CHEMBL2426469)
Show SMILES O=C(N1CCCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCCC(CC1)N1CCCC1
Show InChI InChI=1/C28H42N4O2/c33-27(31-19-5-7-25(13-21-31)29-15-1-2-16-29)23-9-11-24(12-10-23)28(34)32-20-6-8-26(14-22-32)30-17-3-4-18-30/h9-12,25-26H,1-8,13-22H2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440601
PNG
(CHEMBL2426480)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(c1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C36H54N6O3/c43-34(40-21-9-29(10-22-40)37-15-1-2-16-37)28-7-8-32(35(44)41-23-11-30(12-24-41)38-17-3-4-18-38)33(27-28)36(45)42-25-13-31(14-26-42)39-19-5-6-20-39/h7-8,27,29-31H,1-6,9-26H2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440576
PNG
(CHEMBL2426469)
Show SMILES O=C(N1CCCC(CC1)N1CCCC1)c1ccc(cc1)C(=O)N1CCCC(CC1)N1CCCC1
Show InChI InChI=1/C28H42N4O2/c33-27(31-19-5-7-25(13-21-31)29-15-1-2-16-29)23-9-11-24(12-10-23)28(34)32-20-6-8-26(14-22-32)30-17-3-4-18-30/h9-12,25-26H,1-8,13-22H2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496592
PNG
(CHEMBL3134135)
Show SMILES C(Cc1cccc(c1)N1CCC(CC1)N1CCCC1)N1CCCC1
Show InChI InChI=1S/C21H33N3/c1-2-12-22(11-1)15-8-19-6-5-7-21(18-19)24-16-9-20(10-17-24)23-13-3-4-14-23/h5-7,18,20H,1-4,8-17H2
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n/an/a 120n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440568
PNG
(CHEMBL2426476)
Show SMILES Brc1cc(ccc1C(=O)N1CCC(CC1)N1CCCC1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H37BrN4O2/c27-24-19-20(25(32)30-15-7-21(8-16-30)28-11-1-2-12-28)5-6-23(24)26(33)31-17-9-22(10-18-31)29-13-3-4-14-29/h5-6,19,21-22H,1-4,7-18H2
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n/an/a 120n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50496599
PNG
(CHEMBL3134136)
Show SMILES C(N1CCCC1)c1cccc(c1)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C20H31N3/c1-2-11-21(10-1)17-18-6-5-7-20(16-18)23-14-8-19(9-15-23)22-12-3-4-13-22/h5-7,16,19H,1-4,8-15,17H2
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n/an/a 120n/an/an/an/an/an/a



University of North Carolina

Curated by ChEMBL


Assay Description
Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...


Medchemcomm 4: 1501-1507 (2013)

More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440591
PNG
(CHEMBL2426490)
Show SMILES O=C(N1CCC(CC1)C1CCCN1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1/C26H38N4O2/c31-25(29-16-9-20(10-17-29)24-4-3-13-27-24)21-5-7-22(8-6-21)26(32)30-18-11-23(12-19-30)28-14-1-2-15-28/h5-8,20,23-24,27H,1-4,9-19H2
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n/an/a 120n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440601
PNG
(CHEMBL2426480)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(c1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C36H54N6O3/c43-34(40-21-9-29(10-22-40)37-15-1-2-16-37)28-7-8-32(35(44)41-23-11-30(12-24-41)38-17-3-4-18-38)33(27-28)36(45)42-25-13-31(14-26-42)39-19-5-6-20-39/h7-8,27,29-31H,1-6,9-26H2
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n/an/a 120n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440605
PNG
(CHEMBL2424677)
Show SMILES CCN1Cc2ccc(NC(=O)c3ccc(C(=O)N4CCC(CC4)C4CCCN4)c(Nc4ccccc4)c3)cc2C1
Show InChI InChI=1/C33H39N5O2/c1-2-37-21-25-10-12-28(19-26(25)22-37)36-32(39)24-11-13-29(31(20-24)35-27-7-4-3-5-8-27)33(40)38-17-14-23(15-18-38)30-9-6-16-34-30/h3-5,7-8,10-13,19-20,23,30,34-35H,2,6,9,14-18,21-22H2,1H3,(H,36,39)
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440565
PNG
(CHEMBL2426358)
Show SMILES Fc1c(F)c(C(=O)N2CCC(CC2)N2CCCC2)c(F)c(F)c1C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C26H34F4N4O2/c27-21-19(25(35)33-13-5-17(6-14-33)31-9-1-2-10-31)22(28)24(30)20(23(21)29)26(36)34-15-7-18(8-16-34)32-11-3-4-12-32/h17-18H,1-16H2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440598
PNG
(CHEMBL2426483)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(CN2CCC(CC2)N2CCCC2)cc1
Show InChI InChI=1S/C26H40N4O/c31-26(30-19-11-25(12-20-30)29-15-3-4-16-29)23-7-5-22(6-8-23)21-27-17-9-24(10-18-27)28-13-1-2-14-28/h5-8,24-25H,1-4,9-21H2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440605
PNG
(CHEMBL2424677)
Show SMILES CCN1Cc2ccc(NC(=O)c3ccc(C(=O)N4CCC(CC4)C4CCCN4)c(Nc4ccccc4)c3)cc2C1
Show InChI InChI=1/C33H39N5O2/c1-2-37-21-25-10-12-28(19-26(25)22-37)36-32(39)24-11-13-29(31(20-24)35-27-7-4-3-5-8-27)33(40)38-17-14-23(15-18-38)30-9-6-16-34-30/h3-5,7-8,10-13,19-20,23,30,34-35H,2,6,9,14-18,21-22H2,1H3,(H,36,39)
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440598
PNG
(CHEMBL2426483)
Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(CN2CCC(CC2)N2CCCC2)cc1
Show InChI InChI=1S/C26H40N4O/c31-26(30-19-11-25(12-20-30)29-15-3-4-16-29)23-7-5-22(6-8-23)21-27-17-9-24(10-18-27)28-13-1-2-14-28/h5-8,24-25H,1-4,9-21H2
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440592
PNG
(CHEMBL2426489)
Show SMILES C[N+]1(CCCC1)C1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCC1
Show InChI InChI=1S/C27H41N4O2/c1-31(20-4-5-21-31)25-12-18-30(19-13-25)27(33)23-8-6-22(7-9-23)26(32)29-16-10-24(11-17-29)28-14-2-3-15-28/h6-9,24-25H,2-5,10-21H2,1H3/q+1
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)


(Homo sapiens (Human))
BDBM50440608
PNG
(CHEMBL2426374)
Show SMILES CCN1Cc2ccc(NC(=O)c3ccc(cc3)C(=O)N3CC4CCC(C3)C4N3CCCC3)cc2C1
Show InChI InChI=1/C29H36N4O2/c1-2-31-16-22-11-12-26(15-25(22)17-31)30-28(34)20-5-7-21(8-6-20)29(35)33-18-23-9-10-24(19-33)27(23)32-13-3-4-14-32/h5-8,11-12,15,23-24,27H,2-4,9-10,13-14,16-19H2,1H3,(H,30,34)
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n/an/a 150n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assay


J Med Chem 56: 7358-71 (2013)


Article DOI: 10.1021/jm400919p
BindingDB Entry DOI: 10.7270/Q2B27WRP
More data for this
Ligand-Target Pair
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