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Found 29 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1B'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155772
PNG
(CHEMBL3780774)
PDB

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Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155771
PNG
(CHEMBL3781560)
PDB

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PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155769
PNG
(CHEMBL3780542)
PDB

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PubMed
n/an/a 5.70E+3n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50151583
PNG
(CHEMBL3774920)
PDB

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PubMed
n/an/a 7.51E+3n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155764
PNG
(CHEMBL3780674)
PDB

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PubMed
n/an/a 1.16E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155766
PNG
(CHEMBL3780374)
PDB

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n/an/a 1.26E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50151585
PNG
(CHEMBL3774476)
PDB

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PubMed
n/an/a 1.32E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155770
PNG
(CHEMBL3781885)
PDB

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n/an/a 1.49E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50151584
PNG
(CHEMBL3775613)
PDB

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n/an/a 2.32E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50445336
PNG
(CHEMBL1797639)
Show SMILES NC1CC1c1cccc(OCC[C@H](NC(=O)c2ccccc2)C(=O)NCc2ccccc2)c1
Show InChI InChI=1S/C27H29N3O3/c28-24-17-23(24)21-12-7-13-22(16-21)33-15-14-25(30-26(31)20-10-5-2-6-11-20)27(32)29-18-19-8-3-1-4-9-19/h1-13,16,23-25H,14-15,17-18,28H2,(H,29,32)(H,30,31)/t23?,24?,25-/m0/s1
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n/an/a 2.60E+4n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155768
PNG
(CHEMBL3781494)
PDB

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n/an/a 3.47E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50240772
PNG
((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Show SMILES N[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m0/s1
PDB

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Article
PubMed
n/an/a 3.49E+4n/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Inhibition of recombinant LSD2 (22 to 822 aa) (unknown origin) expressed in Escherichia coli BL21(DE) by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50441978
PNG
(CHEMBL2334501)
Show SMILES Cc1ccc(Cn2cc(CSC(=S)N3CCN(CC3)C(=O)OC(C)(C)C)nn2)cc1
Show InChI InChI=1S/C21H29N5O2S2/c1-16-5-7-17(8-6-16)13-26-14-18(22-23-26)15-30-20(29)25-11-9-24(10-12-25)19(27)28-21(2,3)4/h5-8,14H,9-13,15H2,1-4H3
PDB

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PubMed
n/an/a 3.66E+4n/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Inhibition of recombinant LSD2 (22 to 822 aa) (unknown origin) expressed in Escherichia coli BL21(DE) by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155580
PNG
(CHEMBL3781125)
PDB

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n/an/a 3.66E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155773
PNG
(CHEMBL3781751)
PDB

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PubMed
n/an/a 4.35E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155581
PNG
(CHEMBL3781124)
PDB

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PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50441979
PNG
(CHEMBL2334497)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=S)SCc1cn(Cc2ccccc2F)nn1
Show InChI InChI=1S/C20H26FN5O2S2/c1-20(2,3)28-18(27)24-8-10-25(11-9-24)19(29)30-14-16-13-26(23-22-16)12-15-6-4-5-7-17(15)21/h4-7,13H,8-12,14H2,1-3H3
PDB

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PubMed
n/an/a 4.91E+4n/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Inhibition of recombinant LSD2 (22 to 822 aa) (unknown origin) expressed in Escherichia coli BL21(DE) by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155580
PNG
(CHEMBL3781125)
PDB

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PubMed
n/an/a 4.93E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50151587
PNG
(CHEMBL3774486)
PDB

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PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50151586
PNG
(CHEMBL3774631)
PDB

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n/an/a>5.00E+4n/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155763
PNG
(CHEMBL3780391)
PDB

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PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155579
PNG
(CHEMBL3546846)
PDB

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PubMed
n/an/a 5.83E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50121213
PNG
(CHEMBL3622371)
Show SMILES O=C(NCc1ccccc1)[C@H](CCCCNC1CC1c1ccccc1)NC(=O)c1ccccc1
Show InChI InChI=1/C29H33N3O2/c33-28(24-16-8-3-9-17-24)32-26(29(34)31-21-22-12-4-1-5-13-22)18-10-11-19-30-27-20-25(27)23-14-6-2-7-15-23/h1-9,12-17,25-27,30H,10-11,18-21H2,(H,31,34)(H,32,33)/t25?,26-,27?/s2
PDB

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PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50155765
PNG
(CHEMBL3781329)
PDB

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n/an/a 7.47E+4n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50140043
PNG
(CHEMBL3765529)
PDB

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n/an/a 2.30E+5n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50140044
PNG
(CHEMBL3764353)
PDB

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n/an/a 2.50E+5n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50140045
PNG
(CHEMBL3764836)
PDB

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n/an/a>5.40E+5n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50113851
PNG
((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Show SMILES NC1CC1c1ccccc1
Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2
PDB

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n/an/a 2.30E+6n/an/an/an/an/an/a



Waseda University

Curated by ChEMBL




Citation and Details
More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1B


(Homo sapiens)
BDBM50346864
PNG
(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Show SMILES NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C26H27N3O3/c27-23-16-22(23)20-11-13-21(14-12-20)28-25(30)24(15-18-7-3-1-4-8-18)29-26(31)32-17-19-9-5-2-6-10-19/h1-14,22-24H,15-17,27H2,(H,28,30)(H,29,31)
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3.80E+4n/an/an/an/an/an/an/an/a



Kyoto Prefectural University of Medicine

Curated by ChEMBL


Assay Description
Inhibition of LSD2


Citation and Details
More data for this
Ligand-Target Pair