Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16530![]() (2-arylpyridazin-3-one, 36 | N-{3-[(2-chlorophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421141![]() (CHEMBL2088578) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421140![]() (CHEMBL2088591) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50317579![]() (6-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-2H-q...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421137![]() (CHEMBL2088588) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16524![]() (2-arylpyridazin-3-one, 30 | 2-{3-[(2-chlorophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50317588![]() (6-(2,4-difluorophenyl)-1-(2-fluoro-5-(5-methyl-1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50317583![]() (1-(2,6-difluoro-4-(5-methyl-1,3,4-oxadiazol-2-yl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16525![]() (2-arylpyridazin-3-one, 31 | 2-{3-[(2-chloro-4-fluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421127![]() (CHEMBL2088582) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122916![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16527![]() (2-arylpyridazin-3-one, 33 | N-{3-[(2-chlorophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16529![]() (2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16528![]() (2-arylpyridazin-3-one, 34 | N-{3-[(2-chlorophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421133![]() (CHEMBL2088575) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16526![]() (2-amino-N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122920![]() (6-[2-(2,3-Dichloro-phenyl)-imidazo[1,2-a]pyridin-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421132![]() (CHEMBL2088579) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 53.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122915![]() (2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122922![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421139![]() (CHEMBL2088590) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421128![]() (CHEMBL2088583) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122914![]() (6-(2-(2,4-difluorophenyl)imidazo[1,2-a]pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421125![]() (CHEMBL2088586) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122908![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421138![]() (CHEMBL2088589) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122918![]() (2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16521![]() (2-arylpyridazin-3-one, 27 | 6-[(2-chloro-4-fluorop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421136![]() (CHEMBL2088587) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122913![]() (6-[2-(2,4-Difluoro-phenyl)-imidazo[1,2-a]pyridin-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122910![]() (2-(2,6-Dichloro-phenyl)-6-[2-(4-fluoro-phenyl)-imi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 153 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122923![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421134![]() (CHEMBL2088576) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421130![]() (CHEMBL2088580) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16522![]() (2-arylpyridazin-3-one, 28 | 6-[(3-aminopropyl)(2-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 211 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421135![]() (CHEMBL2088577) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421126![]() (CHEMBL2088585) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122921![]() (2-(2-Chloro-phenyl)-6-[2-(3-trifluoromethyl-phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421129![]() (CHEMBL2088584) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16515![]() (2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16517![]() (2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16523![]() (2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122911![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16518![]() (2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122912![]() (2-(2,6-Dichloro-phenyl)-6-[2-(2,3-dichloro-phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16516![]() (2-(2-chlorophenyl)-6-[(2-methoxyphenyl)amino]-2,3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP Kinase p38 beta (Mus musculus (mouse)) | BDBM16513![]() (2-(2-chlorophenyl)-6-[(2-chlorophenyl)amino]-2,3-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea... | Bioorg Med Chem Lett 16: 5809-13 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50122919![]() (6-[2-(2-Chloro-4-fluoro-phenyl)-imidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2) | J Med Chem 46: 349-52 (2003) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase p38 beta (Mus musculus (mouse)) | BDBM50421131![]() (CHEMBL2088581) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assay | Bioorg Med Chem Lett 22: 5979-83 (2012) | |||||||||||
More data for this Ligand-Target Pair |