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Found 199 hits Enz. Inhib. hit(s) with Target = 'Macrophage-stimulating protein receptor'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50399540
PNG
(FORETINIB)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
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n/an/a 3.40n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of Ron (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay


Bioorg Med Chem 23: 4410-22 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50399540
PNG
(FORETINIB)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
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n/an/a 3.40n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, PR China.

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (Ron)


(Homo sapiens (Human))
BDBM50399540
PNG
(FORETINIB)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
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n/an/a 3.52n/an/an/an/an/an/a



Shenyang Pharmaceutical University, Ministry of Education



Assay Description
The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (Ron)


(Homo sapiens (Human))
BDBM120816
PNG
((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopro...)
Show SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C35H33F4N5O5/c1-22-25(34(45)44(42-22)29-7-4-3-6-26(29)35(37,38)39)21-41-23-8-9-31(27(36)18-23)49-30-10-11-40-28-20-33(32(46-2)19-24(28)30)48-15-5-12-43-13-16-47-17-14-43/h3-4,6-11,18-21,42H,5,12-17H2,1-2H3/b41-21+
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n/an/a 4.24n/an/an/an/an/an/a



Shenyang Pharmaceutical University, Ministry of Education



Assay Description
The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50347659
PNG
(CHEMBL1802916 | MK-2461)
Show SMILES CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
Show InChI InChI=1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-9-22-23(25-11-17)6-4-16-3-5-19(10-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1
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n/an/a 7n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human Ron


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50427138
PNG
(CHEMBL2323775 | MK-8033)
Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1
Show InChI InChI=1S/C25H21N5O3S/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32,33)29-14-21-4-2-3-9-26-21/h2-13,15,29H,14,16H2,1H3
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n/an/a 7n/an/an/an/an/an/a



Merck& Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) by TR-FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50347681
PNG
(CHEMBL1802829)
Show SMILES CN(C)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
Show InChI InChI=1S/C20H19N5O3S/c1-24(2)29(27,28)23-16-6-4-13-5-7-19-18(20(26)17(13)9-16)8-14(10-21-19)15-11-22-25(3)12-15/h4-12,23H,1-3H3
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n/an/a 7n/an/an/an/an/an/a



Merck& Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) by TR-FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50091030
PNG
(CHEMBL3582033)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4ccn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/p+1/t10-,13-/m1/s1
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n/an/a 10n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 10n/an/an/an/an/an/a



Laboratoires ChemRF Inc. / ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3706-10 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM24466
PNG
(1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquino...)
Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)nc3)ccnc2c1
Show InChI InChI=1S/C30H29N5O5/c1-19-27(29(37)35(20-8-6-5-7-9-20)34(19)18-30(2,3)38)28(36)33-26-13-11-22(17-32-26)40-25-14-15-31-24-16-21(39-4)10-12-23(24)25/h5-17,38H,18H2,1-4H3,(H,32,33,36)
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n/an/a 10n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of RON by HTRF assay


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 12n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 12n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50090969
PNG
(CHEMBL3582034)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4ncn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-13-20(34-14-37)23-12-19-25(41-23)22(9-10-33-19)40-21-8-7-16(11-18(21)29)36-27(39)24-26(28(30,31)32)38(15-35-24)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 13n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50384006
PNG
(CHEMBL2032274)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23)
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n/an/a 14n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of Ron


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115203
PNG
(CHEMBL3608551)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4-c4cccnc4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C32H22FN7O2S/c1-39-18-26(36-19-39)29-15-25-31(43-29)28(11-13-35-25)42-27-10-9-21(14-24(27)33)38-32(41)23-17-37-40(22-7-3-2-4-8-22)30(23)20-6-5-12-34-16-20/h2-19H,1H3,(H,38,41)
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n/an/a 14n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317324
PNG
(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C28H20F4N4O4/c1-38-24-13-18-21(14-25(24)39-2)33-11-10-22(18)40-23-9-8-16(12-20(23)29)35-27(37)19-15-34-36(26(19)28(30,31)32)17-6-4-3-5-7-17/h3-15H,1-2H3,(H,35,37)
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n/an/a 16n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50090968
PNG
(CHEMBL3582035)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C27H17F4N7O2S/c1-37-13-19(33-14-37)22-12-18-24(41-22)21(9-10-32-18)40-20-8-7-15(11-17(20)28)34-26(39)23-25(27(29,30)31)38(36-35-23)16-5-3-2-4-6-16/h2-14H,1H3,(H,34,39)
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n/an/a 17n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50439772
PNG
(CHEMBL2419669)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(F)cc4F)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C33H34F3N5O4/c1-21-9-13-41(14-10-21)12-3-15-44-32-19-28-25(18-31(32)43-2)29(8-11-37-28)45-30-7-6-24(17-27(30)36)39-33(42)40-38-20-22-4-5-23(34)16-26(22)35/h4-8,11,16-21H,3,9-10,12-15H2,1-2H3,(H2,39,40,42)
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n/an/a 19n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) using poly(Glu,Tyr) as substrate after 30 mins by HTRF assay


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115196
PNG
(CHEMBL3608549)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4-c4ccccn4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C32H22FN7O2S/c1-39-18-26(36-19-39)29-16-25-31(43-29)28(12-14-35-25)42-27-11-10-20(15-23(27)33)38-32(41)22-17-37-40(21-7-3-2-4-8-21)30(22)24-9-5-6-13-34-24/h2-19H,1H3,(H,38,41)
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n/an/a 23n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115201
PNG
(CHEMBL3608544)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4-c4ccccc4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H23FN6O2S/c1-39-19-27(36-20-39)30-17-26-32(43-30)29(14-15-35-26)42-28-13-12-22(16-25(28)34)38-33(41)24-18-37-40(23-10-6-3-7-11-23)31(24)21-8-4-2-5-9-21/h2-20H,1H3,(H,38,41)
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n/an/a 23n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115197
PNG
(CHEMBL3608547)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4-c4ccccc4F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H22F2N6O2S/c1-40-18-27(37-19-40)30-16-26-32(44-30)29(13-14-36-26)43-28-12-11-20(15-25(28)35)39-33(42)23-17-38-41(21-7-3-2-4-8-21)31(23)22-9-5-6-10-24(22)34/h2-19H,1H3,(H,39,42)
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n/an/a 25n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50437161
PNG
(CHEMBL2401832)
Show SMILES C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)C(N)=O)c1c(Cl)ccc(F)c1Cl
Show InChI InChI=1S/C21H19Cl2FN4O3/c1-10(16-14(22)2-3-15(24)17(16)23)31-19-18-12(8-27-20(19)25)13(9-30-18)11-4-6-28(7-5-11)21(26)29/h2-4,8-10H,5-7H2,1H3,(H2,25,27)(H2,26,29)/t10-/m1/s1
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n/an/a 25n/an/an/an/an/an/a



OSI Pharmaceuticals, LLC

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) autophosphorylation


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115202
PNG
(CHEMBL3608550)
Show SMILES COc1cccc(c1)-c1c(cnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3cc(sc23)-c2cn(C)cn2)c(F)c1
Show InChI InChI=1S/C34H25FN6O3S/c1-40-19-28(37-20-40)31-17-27-33(45-31)30(13-14-36-27)44-29-12-11-22(16-26(29)35)39-34(42)25-18-38-41(23-8-4-3-5-9-23)32(25)21-7-6-10-24(15-21)43-2/h3-20H,1-2H3,(H,39,42)
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n/an/a 27n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50102822
PNG
(CHEMBL3339360)
Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1
Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+
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n/an/a 29n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, 103 Wenhua Road, Shenhe District, PR China.

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317338
PNG
(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Show SMILES CN(C)C(=O)c1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C32H22F4N6O3S/c1-41(2)31(44)18-8-10-23(38-16-18)27-15-24-28(46-27)26(12-13-37-24)45-25-11-9-19(14-22(25)33)40-30(43)21-17-39-42(29(21)32(34,35)36)20-6-4-3-5-7-20/h3-17H,1-2H3,(H,40,43)
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n/an/a 30n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317335
PNG
(CHEMBL1095356 | N-(4-(2-(4-(dimethylcarbamoyl)phen...)
Show SMILES CN(C)C(=O)c1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H23F4N5O3S/c1-41(2)32(44)20-10-8-19(9-11-20)28-17-25-29(46-28)27(14-15-38-25)45-26-13-12-21(16-24(26)34)40-31(43)23-18-39-42(30(23)33(35,36)37)22-6-4-3-5-7-22/h3-18H,1-2H3,(H,40,43)
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n/an/a 30n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 30n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON phosphorylation in human PC3 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 30n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON phosphorylation in human HT29 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50114398
PNG
(CHEMBL3609808)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(cc3F)N3CCc4c(cnn4-c4ccccc4)C3=O)c2s1
Show InChI InChI=1S/C29H21FN6O2S/c1-34-16-23(32-17-34)27-14-22-28(39-27)26(9-11-31-22)38-25-8-7-19(13-21(25)30)35-12-10-24-20(29(35)37)15-33-36(24)18-5-3-2-4-6-18/h2-9,11,13-17H,10,12H2,1H3
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n/an/a 30n/an/an/an/an/an/a



Laboratoires ChemRF Inc. / ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3706-10 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115200
PNG
(CHEMBL3608545)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cn(nc4-c4ccccc4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H23FN6O2S/c1-39-19-27(36-20-39)30-17-26-32(43-30)29(14-15-35-26)42-28-13-12-22(16-25(28)34)37-33(41)24-18-40(23-10-6-3-7-11-23)38-31(24)21-8-4-2-5-9-21/h2-20H,1H3,(H,37,41)
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n/an/a 32n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50114396
PNG
(CHEMBL3609807)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(cc3F)N3CCCc4c(cnn4-c4ccccc4)C3=O)c2s1
Show InChI InChI=1S/C30H23FN6O2S/c1-35-17-24(33-18-35)28-15-23-29(40-28)27(11-12-32-23)39-26-10-9-20(14-22(26)31)36-13-5-8-25-21(30(36)38)16-34-37(25)19-6-3-2-4-7-19/h2-4,6-7,9-12,14-18H,5,8,13H2,1H3
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n/an/a 34n/an/an/an/an/an/a



Laboratoires ChemRF Inc. / ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3706-10 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317339
PNG
(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Show SMILES COCCNC(=O)c1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H24F4N6O4S/c1-46-14-13-39-31(44)19-7-9-24(40-17-19)28-16-25-29(48-28)27(11-12-38-25)47-26-10-8-20(15-23(26)34)42-32(45)22-18-41-43(30(22)33(35,36)37)21-5-3-2-4-6-21/h2-12,15-18H,13-14H2,1H3,(H,39,44)(H,42,45)
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n/an/a 40n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50090966
PNG
(CHEMBL3582037)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccc(F)cc4)cc3F)c2s1
Show InChI InChI=1S/C28H17F5N6O2S/c1-38-13-21(35-14-38)24-11-20-25(42-24)23(8-9-34-20)41-22-7-4-16(10-19(22)30)37-27(40)18-12-36-39(26(18)28(31,32)33)17-5-2-15(29)3-6-17/h2-14H,1H3,(H,37,40)
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n/an/a 44n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115199
PNG
(CHEMBL3608312)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4sc(nc4-c4ccccc4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C33H22FN5O2S2/c1-39-18-25(36-19-39)28-17-24-30(42-28)27(14-15-35-24)41-26-13-12-22(16-23(26)34)37-32(40)31-29(20-8-4-2-5-9-20)38-33(43-31)21-10-6-3-7-11-21/h2-19H,1H3,(H,37,40)
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n/an/a 45n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50114394
PNG
(CHEMBL3609805)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(cc3F)N3CC=Cc4c(cnn4-c4ccccc4)C3=O)c2s1
Show InChI InChI=1S/C30H21FN6O2S/c1-35-17-24(33-18-35)28-15-23-29(40-28)27(11-12-32-23)39-26-10-9-20(14-22(26)31)36-13-5-8-25-21(30(36)38)16-34-37(25)19-6-3-2-4-7-19/h2-12,14-18H,13H2,1H3
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n/an/a 49n/an/an/an/an/an/a



Laboratoires ChemRF Inc. / ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3706-10 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50350069
PNG
(CHEMBL1813632)
Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4scc(-c5ccccc5)c34)c(F)c2)c1=O
Show InChI InChI=1S/C30H18F2N4O3S/c31-19-8-11-21(12-9-19)36-14-4-7-22(30(36)38)27(37)35-20-10-13-25(24(32)15-20)39-28-26-23(18-5-2-1-3-6-18)16-40-29(26)34-17-33-28/h1-17H,(H,35,37)
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n/an/a 50n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of RON


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317323
PNG
(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)36-27(39)18-13-35-38(26(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 50n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317333
PNG
((S)-N-(3-fluoro-4-(2-(4-((N-(1-methoxypropan-2-yl)...)
Show SMILES COC[C@H](C)N(Cc1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1)C(C)=O
Show InChI InChI=1S/C37H31F4N5O4S/c1-22(21-49-3)45(23(2)47)20-24-9-11-25(12-10-24)33-18-30-34(51-33)32(15-16-42-30)50-31-14-13-26(17-29(31)38)44-36(48)28-19-43-46(35(28)37(39,40)41)27-7-5-4-6-8-27/h4-19,22H,20-21H2,1-3H3,(H,44,48)/t22-/m0/s1
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n/an/a 60n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317332
PNG
(CHEMBL1095034 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cn1ccnc1-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-12-11-34-26(37)23-14-20-24(41-23)22(9-10-33-20)40-21-8-7-16(13-19(21)29)36-27(39)18-15-35-38(25(18)28(30,31)32)17-5-3-2-4-6-17/h2-15H,1H3,(H,36,39)
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n/an/a 60n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50242737
PNG
((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1
Show InChI InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1
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n/an/a 68n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of Ron by cellular assay


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317334
PNG
(CHEMBL1095036 | N-(3-fluoro-4-(2-(4-((2-(methylsul...)
Show SMILES CS(=O)(=O)CCNCc1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C34H27F4N5O4S2/c1-49(45,46)16-15-39-19-21-7-9-22(10-8-21)30-18-27-31(48-30)29(13-14-40-27)47-28-12-11-23(17-26(28)35)42-33(44)25-20-41-43(32(25)34(36,37)38)24-5-3-2-4-6-24/h2-14,17-18,20,39H,15-16,19H2,1H3,(H,42,44)
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n/an/a 80n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317324
PNG
(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C28H20F4N4O4/c1-38-24-13-18-21(14-25(24)39-2)33-11-10-22(18)40-23-9-8-16(12-20(23)29)35-27(37)19-15-34-36(26(19)28(30,31)32)17-6-4-3-5-7-17/h3-15H,1-2H3,(H,35,37)
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n/an/a 80n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor


(Mus musculus)
BDBM50306682
PNG
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
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n/an/a 80n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of RON in mouse 3T3 cells assessed as growth factor-induced autophosphorylation by sandwich ELISA method


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317340
PNG
(CHEMBL1095361 | N-(4-(2-(1-acetyl-1,2,3,6-tetrahyd...)
Show SMILES CC(=O)N1CCC(=CC1)c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C31H23F4N5O3S/c1-18(41)39-13-10-19(11-14-39)27-16-24-28(44-27)26(9-12-36-24)43-25-8-7-20(15-23(25)32)38-30(42)22-17-37-40(29(22)31(33,34)35)21-5-3-2-4-6-21/h2-10,12,15-17H,11,13-14H2,1H3,(H,38,42)
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n/an/a 90n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317336
PNG
(CHEMBL1095357 | N-(4-(2-(4-((2-(dimethylamino)ethy...)
Show SMILES CN(C)CCN(C)C(=O)c1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C36H30F4N6O3S/c1-44(2)17-18-45(3)35(48)23-11-9-22(10-12-23)31-20-28-32(50-31)30(15-16-41-28)49-29-14-13-24(19-27(29)37)43-34(47)26-21-42-46(33(26)36(38,39)40)25-7-5-4-6-8-25/h4-16,19-21H,17-18H2,1-3H3,(H,43,47)
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n/an/a 90n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50090967
PNG
(CHEMBL3582036)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cn(nc4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C28H18F4N6O2S/c1-37-14-21(34-15-37)24-12-20-25(41-24)23(9-10-33-20)40-22-8-7-16(11-19(22)29)35-27(39)18-13-38(17-5-3-2-4-6-17)36-26(18)28(30,31)32/h2-15H,1H3,(H,35,39)
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n/an/a 95n/an/an/an/an/an/a



ChemRF Laboratories

Curated by ChEMBL


Assay Description
Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317337
PNG
((S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-car...)
Show SMILES CN(C)[C@H]1CCN(C1)C(=O)c1ccc(cc1)-c1cc2nccc(Oc3ccc(NC(=O)c4cnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C37H30F4N6O3S/c1-45(2)26-15-17-46(21-26)36(49)23-10-8-22(9-11-23)32-19-29-33(51-32)31(14-16-42-29)50-30-13-12-24(18-28(30)38)44-35(48)27-20-43-47(34(27)37(39,40)41)25-6-4-3-5-7-25/h3-14,16,18-20,26H,15,17,21H2,1-2H3,(H,44,48)/t26-/m0/s1
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n/an/a 100n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50115198
PNG
(CHEMBL3608546)
Show SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4cc(-c5ccccc5)n(c4)-c4ccccc4)cc3F)c2s1
Show InChI InChI=1S/C34H24FN5O2S/c1-39-20-28(37-21-39)32-18-27-33(43-32)31(14-15-36-27)42-30-13-12-24(17-26(30)35)38-34(41)23-16-29(22-8-4-2-5-9-22)40(19-23)25-10-6-3-7-11-25/h2-21H,1H3,(H,38,41)
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n/an/a 101n/an/an/an/an/an/a



Laboratoires ChemRF Inc./ChemRF Laboratories Inc.

Curated by ChEMBL


Assay Description
Inhibition of human RON


Bioorg Med Chem Lett 25: 3810-5 (2015)

More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50437157
PNG
(CHEMBL2401814)
Show SMILES C[C@H](Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Show InChI InChI=1S/C23H22Cl2FN5O2/c1-12(19-17(24)2-3-18(26)20(19)25)33-22-21-15(9-29-23(22)27)16(11-32-21)13-8-30-31(10-13)14-4-6-28-7-5-14/h2-3,8-12,14,28H,4-7H2,1H3,(H2,27,29)/t12-/m0/s1
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n/an/a 130n/an/an/an/an/an/a



OSI Pharmaceuticals, LLC

Curated by ChEMBL


Assay Description
Inhibition of short-form RON (unknown origin) expressed in human HeLa cells assessed as phosphorylated RON levels after 4 hrs


Citation and Details
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor (RON/MST1R)


(Homo sapiens (Human))
BDBM50317326
PNG
(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Show SMILES Cc1c(cnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3cc(sc23)-c2cn(C)cn2)c(F)c1
Show InChI InChI=1S/C28H21FN6O2S/c1-17-20(14-32-35(17)19-6-4-3-5-7-19)28(36)33-18-8-9-24(21(29)12-18)37-25-10-11-30-22-13-26(38-27(22)25)23-15-34(2)16-31-23/h3-16H,1-2H3,(H,33,36)
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n/an/a 150n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
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