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Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50168995
PNG
((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Show SMILES O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O
Show InChI InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7-,8-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50078117
PNG
((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)
Show SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1
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n/an/a 150n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50339274
PNG
(2-Phenylethyl alpha-D-mannopyranosyl sulfone | CHE...)
Show SMILES OC[C@H]1O[C@@H]([C@@H](O)[C@@H](O)[C@@H]1O)S(=O)(=O)CCc1ccccc1
Show InChI InChI=1S/C14H20O7S/c15-8-10-11(16)12(17)13(18)14(21-10)22(19,20)7-6-9-4-2-1-3-5-9/h1-5,10-18H,6-8H2/t10-,11-,12+,13+,14-/m1/s1
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n/an/a 1.50E+6n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50339273
PNG
(Benzyl alpha-D-mannopyranosyl sulfone | CHEMBL1689...)
Show SMILES OC[C@H]1O[C@@H]([C@@H](O)[C@@H](O)[C@@H]1O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C13H18O7S/c14-6-9-10(15)11(16)12(17)13(20-9)21(18,19)7-8-4-2-1-3-5-8/h1-5,9-17H,6-7H2/t9-,10-,11+,12+,13-/m1/s1
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n/an/a 2.00E+6n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50339272
PNG
((Rs)-2-phenylethyl alpha-D-mannopyranosyl sulfoxid...)
Show SMILES OC[C@H]1O[C@@H]([C@@H](O)[C@@H](O)[C@@H]1O)S(=O)CCc1ccccc1
Show InChI InChI=1S/C14H20O6S/c15-8-10-11(16)12(17)13(18)14(20-10)21(19)7-6-9-4-2-1-3-5-9/h1-5,10-18H,6-8H2/t10-,11-,12+,13+,14-,21?/m1/s1
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PubMed
n/an/a 2.50E+6n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50339275
PNG
((2R,3S,4S,5S,6R)-2-(hexylsulfonyl)-6-(hydroxymethy...)
Show SMILES CCCCCCS(=O)(=O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C12H24O7S/c1-2-3-4-5-6-20(17,18)12-11(16)10(15)9(14)8(7-13)19-12/h8-16H,2-7H2,1H3/t8-,9-,10+,11+,12-/m1/s1
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n/an/a 2.50E+6n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50339276
PNG
((2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(octylsulfony...)
Show SMILES CCCCCCCCS(=O)(=O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C14H28O7S/c1-2-3-4-5-6-7-8-22(19,20)14-13(18)12(17)11(16)10(9-15)21-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13+,14-/m1/s1
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UniChem

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Article
PubMed
n/an/a 2.50E+6n/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B


(Drosophila melanogaster)
BDBM50168995
PNG
((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Show SMILES O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O
Show InChI InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7-,8-/m1/s1
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Article
PubMed
3n/an/an/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Drosophila melanogaster GM2b by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair