Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50383522![]() (CHEMBL2032049) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen San Francisco Curated by ChEMBL | Assay Description Antagonist activity at mouse MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization | Bioorg Med Chem Lett 22: 3781-5 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Macaca mulatta) | BDBM50383522![]() (CHEMBL2032049) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen San Francisco Curated by ChEMBL | Assay Description Antagonist activity at rhesus monkey MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization | Bioorg Med Chem Lett 22: 3781-5 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50383522![]() (CHEMBL2032049) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen San Francisco Curated by ChEMBL | Assay Description Antagonist activity at rat MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization | Bioorg Med Chem Lett 22: 3781-5 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50383112![]() (CHEMBL2029372) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388442![]() (CHEMBL2059408) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50162116![]() (2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against Melanin-concentrating hormone receptor 1 in diet-induced obese mice | Bioorg Med Chem Lett 15: 2752-7 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388443![]() (CHEMBL2059409) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50383112![]() (CHEMBL2029372) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 1 hr by scintillation counting | J Med Chem 55: 2353-66 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50219047![]() (CHEMBL245231 | N-(3-(1-(4-(3,4-difluorophenoxy)ben...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of rat MCH1R receptor | Bioorg Med Chem Lett 19: 5339-45 (2009) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50167565![]() (1-[1-(2-Isobutylamino-ethyl)-1H-indazol-5-yl]-3-(4...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH | Bioorg Med Chem Lett 15: 2752-7 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388452![]() (CHEMBL2059420) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388444![]() (CHEMBL2059410) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351312![]() (CHEMBL1818800) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351322![]() (CHEMBL1818810) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50167552![]() (1-[1-(2-Cyclopentylamino-ethyl)-1H-indazol-5-yl]-3...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH | Bioorg Med Chem Lett 15: 2752-7 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388460![]() (CHEMBL2059513) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351313![]() (CHEMBL1818801) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388457![]() (CHEMBL2059426) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351308![]() (CHEMBL1818795) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50168509![]() (CHEMBL188937 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass... | Bioorg Med Chem Lett 15: 3412-6 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM119755![]() (US8685958, 4 | US8685958, 5) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388458![]() (CHEMBL2059511) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351323![]() (CHEMBL1818811) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50358743![]() (CHEMBL1922270) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells by aequorin bioluminescence assay | Bioorg Med Chem Lett 21: 7001-5 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Macaca fascicularis) | BDBM50358743![]() (CHEMBL1922270) | GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Curated by ChEMBL | Assay Description Antagonist activity at cynomolgus monkey MCHR1 | Bioorg Med Chem Lett 21: 7001-5 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351324![]() (CHEMBL1818901) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388450![]() (CHEMBL2059418) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50192518![]() (1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPA | Bioorg Med Chem Lett 16: 5066-72 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351297![]() (CHEMBL1818783) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351314![]() (CHEMBL1818802) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388454![]() (CHEMBL2059422) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50167554![]() (1-(4-Phenoxy-phenyl)-3-[1-(2-pyrrolidin-1-yl-ethyl...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH | Bioorg Med Chem Lett 15: 2752-7 (2005) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50159340![]() (CHEMBL3786169) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50159145![]() (CHEMBL3786685) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50391543![]() (CHEMBL2147477) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
LEO Pharma Curated by ChEMBL | Assay Description Antagonist activity at rat MCH1 receptor expressed in HEK 293T cells assessed as inhibition of MCH-induced Ca2+ mobilization after 10 mins by FLIPR a... | Bioorg Med Chem Lett 22: 6039-47 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351297![]() (CHEMBL1818783) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50351318![]() (CHEMBL1818806) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 19: 5539-52 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50149456![]() (CHEMBL3769702) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]-MCH (4 to 19 residues) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation counting analysis | J Med Chem 59: 1116-39 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50357508![]() (CHEMBL1914637) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [125I]-MCH(4-19) from rat MCHR1 expressed in CHO cells | Bioorg Med Chem 19: 6261-73 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388445![]() (CHEMBL2059411) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50388449![]() (CHEMBL2059417) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation counting | J Med Chem 55: 4336-51 (2012) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50192531![]() (1-(2-chlorophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of [125I]MCH binding to mouse MCHR1 expressed in HEK293 cells by HT-SPA | Bioorg Med Chem Lett 16: 5066-72 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50159339![]() (CHEMBL3786841) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM119758![]() (US8685958, 7 | US8685958, 8) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Mus musculus) | BDBM50159341![]() (CHEMBL3786346) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysis | J Med Chem 59: 2497-511 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50357504![]() (CHEMBL1914633) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [125I]-MCH(4-19) from rat MCHR1 expressed in CHO cells | Bioorg Med Chem 19: 6261-73 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50149462![]() (CHEMBL3771182) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]-MCH (4 to 19 residues) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation counting analysis | J Med Chem 59: 1116-39 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50357503![]() (CHEMBL1914632) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [125I]-MCH(4-19) from rat MCHR1 expressed in CHO cells | Bioorg Med Chem 19: 6261-73 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50189576![]() ((R)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3...) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description Activity at chimeric rat/human MCH1R by accumulation of GTPgammaS | J Med Chem 49: 3753-6 (2006) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GPR24 (RAT) | BDBM50149457![]() (CHEMBL3771335) | Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars AffyNet ![]() | PubMed | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Displacement of [125I]-MCH (4 to 19 residues) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation counting analysis | J Med Chem 59: 1116-39 (2016) | |||||||||||
More data for this Ligand-Target Pair |
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