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Found 585 hits Enz. Inhib. hit(s) with Target = 'Myristoyl-CoA:protein N-myristoyltransferase (Nmt)'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50121716
PNG
((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...)
Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccc(C)cn1
Show InChI InChI=1S/C25H25N3O3/c1-17-9-10-20(28-14-17)24(29)25-18(2)23-21(7-3-8-22(23)31-25)30-13-5-12-27-16-19-6-4-11-26-15-19/h3-4,6-11,14-15,27H,5,12-13,16H2,1-2H3
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n/an/a 0.390n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50121716
PNG
((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...)
Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccc(C)cn1
Show InChI InChI=1S/C25H25N3O3/c1-17-9-10-20(28-14-17)24(29)25-18(2)23-21(7-3-8-22(23)31-25)30-13-5-12-27-16-19-6-4-11-26-15-19/h3-4,6-11,14-15,27H,5,12-13,16H2,1-2H3
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n/an/a 0.390n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207643
PNG
((1S,3R)-N-(2-(cyclopentanecarboxamido)benzo[d]thia...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1
Show InChI InChI=1S/C31H34N4O2S/c36-29(22-7-2-3-8-22)35-31-34-27-15-14-26(18-28(27)38-31)33-30(37)24-10-5-11-25(17-24)32-19-20-12-13-21-6-1-4-9-23(21)16-20/h1,4,6,9,12-16,18,22,24-25,32H,2-3,5,7-8,10-11,17,19H2,(H,33,37)(H,34,35,36)/t24-,25+/m0/s1
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n/an/a 0.490n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207643
PNG
((1S,3R)-N-(2-(cyclopentanecarboxamido)benzo[d]thia...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1
Show InChI InChI=1S/C31H34N4O2S/c36-29(22-7-2-3-8-22)35-31-34-27-15-14-26(18-28(27)38-31)33-30(37)24-10-5-11-25(17-24)32-19-20-12-13-21-6-1-4-9-23(21)16-20/h1,4,6,9,12-16,18,22,24-25,32H,2-3,5,7-8,10-11,17,19H2,(H,33,37)(H,34,35,36)/t24-,25+/m0/s1
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n/an/a 0.490n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50121720
PNG
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nccn1C
Show InChI InChI=1S/C23H24N4O3/c1-16-20-18(29-13-5-10-25-15-17-6-4-9-24-14-17)7-3-8-19(20)30-22(16)21(28)23-26-11-12-27(23)2/h3-4,6-9,11-12,14,25H,5,10,13,15H2,1-2H3
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n/an/a 1n/an/an/an/an/an/a



Nippon Roche Research Center



Assay Description
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...


Chem Biol 9: 1119-28 (2002)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185107
PNG
(US9156811, DDD100868)
Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccc2CCCN(C)Cc2c1
Show InChI InChI=1S/C26H34N4O2S/c1-18(2)15-25-26(19(3)30(5)27-25)28-33(31,32)24-12-10-21(11-13-24)22-9-8-20-7-6-14-29(4)17-23(20)16-22/h8-13,16,18H,6-7,14-15,17H2,1-5H3,(H-,28,31,32)
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n/an/a 2n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207640
PNG
(CHEMBL254011 | N-(2-(cyclobutanecarboxamido)benzo[...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCC1
Show InChI InChI=1S/C30H32N4O2S/c35-28(21-7-3-8-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-9-4-10-24(16-23)31-18-19-11-12-20-5-1-2-6-22(20)15-19/h1-2,5-6,11-15,17,21,23-24,31H,3-4,7-10,16,18H2,(H,32,36)(H,33,34,35)
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n/an/a 2.30n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207640
PNG
(CHEMBL254011 | N-(2-(cyclobutanecarboxamido)benzo[...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCC1
Show InChI InChI=1S/C30H32N4O2S/c35-28(21-7-3-8-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-9-4-10-24(16-23)31-18-19-11-12-20-5-1-2-6-22(20)15-19/h1-2,5-6,11-15,17,21,23-24,31H,3-4,7-10,16,18H2,(H,32,36)(H,33,34,35)
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n/an/a 2.30n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50364113
PNG
(CHEMBL1230468)
Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3
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n/an/a 3n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184848
PNG
(US9156811, DDD85646)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24H,6-9H2,1-3H3,(H-,27,30,31)
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n/an/a 3n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184977
PNG
(US9156811, DDD88646)
Show SMILES CCN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C23H28Cl2N6O2S/c1-5-31(22-15(2)28-29(4)16(22)3)34(32,33)23-19(24)12-18(13-20(23)25)17-6-7-27-21(14-17)30-10-8-26-9-11-30/h6-7,12-14,26H,5,8-11H2,1-4H3
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n/an/a 3n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50364113
PNG
(CHEMBL1230468)
Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3
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n/an/a 3n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184854
PNG
(US9156811, DDD86206)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H25ClN6O2S/c1-14-21(15(2)27(3)25-14)26-31(29,30)19-5-4-16(12-18(19)22)17-6-7-24-20(13-17)28-10-8-23-9-11-28/h4-7,12-13,23H,8-11H2,1-3H3,(H-,26,29,30)
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n/an/a 3n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184902
PNG
(US9156811, DDD86481)
Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)31(4)29-21)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27H,7-11H2,1-4H3,(H-,30,33,34)
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n/an/a 3n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184978
PNG
(US9156811, DDD90022)
Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)26(3)25-14)27(4)30(28,29)21-18(22)12-17(13-19(21)23)7-5-6-16-8-10-24-11-9-16/h12-13,16,24H,5-11H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50109879
PNG
(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Show SMILES Cc1c(COc2cccc(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12
Show InChI InChI=1S/C25H24F2N2O3/c1-17-23(16-31-22-10-2-7-19(26)25(22)27)32-21-9-3-8-20(24(17)21)30-13-5-12-29-15-18-6-4-11-28-14-18/h2-4,6-11,14,29H,5,12-13,15-16H2,1H3
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n/an/a 4n/an/an/an/an/an/a



Nippon Roche Research Center



Assay Description
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...


Chem Biol 9: 1119-28 (2002)

More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033418
PNG
(CHEMBL3357685)
Show SMILES CC(C)Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)31(4)29-21)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27,30H,7-11H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033480
PNG
(CHEMBL3357697)
Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C22H32Cl2N4O2S/c1-15-21(16(2)28(4)25-15)26-31(29,30)22-19(23)13-18(14-20(22)24)8-6-5-7-17-9-11-27(3)12-10-17/h13-14,17,26H,5-12H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033485
PNG
(CHEMBL3357702)
Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)28(3)27-14)29(4)33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-26-20(13-16)30-9-7-25-8-10-30/h5-6,11-13,25H,7-10H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185092
PNG
(US9156811, DDD100798)
Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccc2CCCNCc2c1
Show InChI InChI=1S/C25H32N4O2S/c1-17(2)14-24-25(18(3)29(4)27-24)28-32(30,31)23-11-9-20(10-12-23)21-8-7-19-6-5-13-26-16-22(19)15-21/h7-12,15,17,26H,5-6,13-14,16H2,1-4H3,(H-,28,30,31)
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n/an/a 4n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033616
PNG
(CHEMBL3358119)
Show SMILES Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(3)28-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-4-6-16-8-10-27-11-9-16/h12-13,16,22,27H,4-11H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185101
PNG
(US9156811, DDD100807)
Show SMILES Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(3)28-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-4-6-16-8-10-27-11-9-16/h12-13,16,22,27H,4-11H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184992
PNG
(US9156811, DDD90118)
Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1cccc(CN2CCN(C)CC2)c1
Show InChI InChI=1S/C25H31Cl2N5O2S/c1-17-24(18(2)30(4)28-17)31(5)35(33,34)25-22(26)14-21(15-23(25)27)20-8-6-7-19(13-20)16-32-11-9-29(3)10-12-32/h6-8,13-15H,9-12,16H2,1-5H3
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n/an/a 5n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184988
PNG
(US9156811, DDD90107)
Show SMILES CN1CCC(Cc2cccc(c2)-c2ccc(cc2)[S+]([O-])(=O)Nc2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C25H32N4O2S/c1-18-25(19(2)29(4)26-18)27-32(30,31)24-10-8-22(9-11-24)23-7-5-6-21(17-23)16-20-12-14-28(3)15-13-20/h5-11,17,20H,12-16H2,1-4H3,(H-,27,30,31)
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n/an/a 5n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184943
PNG
(US9156811, DDD88193)
Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)28(3)27-14)29(4)33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-26-20(13-16)30-9-7-25-8-10-30/h5-6,11-13,25H,7-10H2,1-4H3
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n/an/a 5n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185083
PNG
(US9156811, DDD100169)
Show SMILES CN1CCC(CC1)OCCCc1cc(Cl)c(c(Cl)c1)[S+]([O-])(=O)N(C(F)F)c1c(C)nn(C)c1C
Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)12-16(13-19(21)24)6-5-11-33-17-7-9-28(3)10-8-17/h12-13,17,22H,5-11H2,1-4H3
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n/an/a 5n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033618
PNG
(CHEMBL3358121)
Show SMILES CN1CCC(CC1)OCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C
Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)12-16(13-19(21)24)6-5-11-33-17-7-9-28(3)10-8-17/h12-13,17,22H,5-11H2,1-4H3
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n/an/a 5n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033617
PNG
(CHEMBL3358120)
Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3
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n/an/a 5n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033482
PNG
(CHEMBL3357699)
Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)27(3)25-14)26-30(28,29)21-18(22)12-17(13-19(21)23)7-5-4-6-16-8-10-24-11-9-16/h12-13,16,24,26H,4-11H2,1-3H3
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n/an/a 5n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50109882
PNG
(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12
Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3
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n/an/a 5.70n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50109882
PNG
(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12
Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3
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n/an/a 5.70n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185108
PNG
(US9156811, DDD100869)
Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1cccc(CNCCc2cccnc2)c1
Show InChI InChI=1S/C29H35N5O2S/c1-21(2)17-28-29(22(3)34(4)32-28)33-37(35,36)27-12-10-25(11-13-27)26-9-5-7-24(18-26)20-31-16-14-23-8-6-15-30-19-23/h5-13,15,18-19,21,31H,14,16-17,20H2,1-4H3,(H-,33,35,36)
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n/an/a 6n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184937
PNG
(US9156811, DDD88186)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1C)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C22H28N6O2S/c1-15-13-18(19-7-8-24-21(14-19)28-11-9-23-10-12-28)5-6-20(15)31(29,30)26-22-16(2)25-27(4)17(22)3/h5-8,13-14,23H,9-12H2,1-4H3,(H-,26,29,30)
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n/an/a 6n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185061
PNG
(US9156811, DDD100144)
Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3
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n/an/a 6n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184965
PNG
(US9156811, DDD88558)
Show SMILES CN1CCN(Cc2cccc(c2)-c2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)Nc2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C24H29Cl2N5O2S/c1-16-23(17(2)30(4)27-16)28-34(32,33)24-21(25)13-20(14-22(24)26)19-7-5-6-18(12-19)15-31-10-8-29(3)9-11-31/h5-7,12-14H,8-11,15H2,1-4H3,(H-,28,32,33)
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n/an/a 7n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50364135
PNG
(CHEMBL1951295)
Show SMILES CN1CCN(Cc2cccc(c2)-c2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C24H29Cl2N5O2S/c1-16-23(17(2)30(4)27-16)28-34(32,33)24-21(25)13-20(14-22(24)26)19-7-5-6-18(12-19)15-31-10-8-29(3)9-11-31/h5-7,12-14,28H,8-11,15H2,1-4H3
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n/an/a 7n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185078
PNG
(US9156811, DDD100164)
Show SMILES CN1CCCN(CCCc2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C22H31Cl2F2N5O2S/c1-15-20(16(2)29(4)27-15)31(22(25)26)34(32,33)21-18(23)13-17(14-19(21)24)7-5-9-30-10-6-8-28(3)11-12-30/h13-14,22H,5-12H2,1-4H3
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n/an/a 7n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184860
PNG
(US9156811, DDD86213)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H26N6O2S/c1-15-21(16(2)26(3)24-15)25-30(28,29)19-6-4-17(5-7-19)18-8-9-23-20(14-18)27-12-10-22-11-13-27/h4-9,14,22H,10-13H2,1-3H3,(H-,25,28,29)
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n/an/a 7n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184903
PNG
(US9156811, DDD87748)
Show SMILES CC1CN(CCN1)c1cc(ccn1)-c1ccc(cc1)[S+]([O-])(=O)Nc1c(C)nn(C)c1C
Show InChI InChI=1/C22H28N6O2S/c1-15-14-28(12-11-23-15)21-13-19(9-10-24-21)18-5-7-20(8-6-18)31(29,30)26-22-16(2)25-27(4)17(22)3/h5-10,13,15,23H,11-12,14H2,1-4H3,(H-,26,29,30)
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n/an/a 8n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184920
PNG
(US9156811, DDD87767)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccnc(c1)N1CCCNCC1
Show InChI InChI=1S/C22H28N6O2S/c1-16-22(17(2)27(3)25-16)26-31(29,30)20-7-5-18(6-8-20)19-9-11-24-21(15-19)28-13-4-10-23-12-14-28/h5-9,11,15,23H,4,10,12-14H2,1-3H3,(H-,26,29,30)
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n/an/a 8n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185080
PNG
(US9156811, DDD100166)
Show SMILES Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCN2CCCNCC2)cc1Cl
Show InChI InChI=1S/C21H29Cl2F2N5O2S/c1-14-19(15(2)28(3)27-14)30(21(24)25)33(31,32)20-17(22)12-16(13-18(20)23)6-4-9-29-10-5-7-26-8-11-29/h12-13,21,26H,4-11H2,1-3H3
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n/an/a 8n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184859
PNG
(US9156811, DDD86212)
Show SMILES CN1CCN(Cc2cccc(c2)-c2ccc(cc2)[S+]([O-])(=O)Nc2c(C)nn(C)c2C)CC1
Show InChI InChI=1S/C24H31N5O2S/c1-18-24(19(2)28(4)25-18)26-32(30,31)23-10-8-21(9-11-23)22-7-5-6-20(16-22)17-29-14-12-27(3)13-15-29/h5-11,16H,12-15,17H2,1-4H3,(H-,26,30,31)
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n/an/a 8n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033619
PNG
(CHEMBL3358122)
Show SMILES CN(C)CCCCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C
Show InChI InChI=1S/C21H30Cl2F2N4O2S/c1-14-19(15(2)28(5)26-14)29(21(24)25)32(30,31)20-17(22)12-16(13-18(20)23)10-8-6-7-9-11-27(3)4/h12-13,21H,6-11H2,1-5H3
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n/an/a 8n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM185023
PNG
(US9156811, DDD99759)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C20H28Cl2N4O2S/c1-13-19(14(2)26(3)24-13)25-29(27,28)20-17(21)11-16(12-18(20)22)6-4-5-15-7-9-23-10-8-15/h11-12,15,23H,4-10H2,1-3H3,(H-,25,27,28)
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n/an/a 8n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM50033478
PNG
(CHEMBL3357695)
Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl
Show InChI InChI=1S/C20H28Cl2N4O2S/c1-13-19(14(2)26(3)24-13)25-29(27,28)20-17(21)11-16(12-18(20)22)6-4-5-15-7-9-23-10-8-15/h11-12,15,23,25H,4-10H2,1-3H3
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n/an/a 8n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207627
PNG
(3-[(naphthalen-2-ylmethyl)-amino]-cyclohexanecarbo...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCCC1
Show InChI InChI=1S/C32H36N4O2S/c37-30(23-8-2-1-3-9-23)36-32-35-28-16-15-27(19-29(28)39-32)34-31(38)25-11-6-12-26(18-25)33-20-21-13-14-22-7-4-5-10-24(22)17-21/h4-5,7,10,13-17,19,23,25-26,33H,1-3,6,8-9,11-12,18,20H2,(H,34,38)(H,35,36,37)
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n/an/a 8.10n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Candida albicans (Yeast))
BDBM50207627
PNG
(3-[(naphthalen-2-ylmethyl)-amino]-cyclohexanecarbo...)
Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCCC1
Show InChI InChI=1S/C32H36N4O2S/c37-30(23-8-2-1-3-9-23)36-32-35-28-16-15-27(19-29(28)39-32)34-31(38)25-11-6-12-26(18-25)33-20-21-13-14-22-7-4-5-10-24(22)17-21/h4-5,7,10,13-17,19,23,25-26,33H,1-3,6,8-9,11-12,18,20H2,(H,34,38)(H,35,36,37)
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n/an/a 8.10n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of Candida albicans N-myristoyltransferse


Citation and Details
More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184923
PNG
(US9156811, DDD87993)
Show SMILES Cc1c(N[S+]([O-])(=O)c2c(Cl)cc(cc2Cl)-c2ccnc(c2)N2CCNCC2)cnn1C
Show InChI InChI=1S/C20H22Cl2N6O2S/c1-13-18(12-25-27(13)2)26-31(29,30)20-16(21)9-15(10-17(20)22)14-3-4-24-19(11-14)28-7-5-23-6-8-28/h3-4,9-12,23H,5-8H2,1-2H3,(H-,26,29,30)
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n/an/a 9n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184939
PNG
(US9156811, DDD88188)
Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1F)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H25FN6O2S/c1-14-21(15(2)27(3)25-14)26-31(29,30)19-5-4-16(12-18(19)22)17-6-7-24-20(13-17)28-10-8-23-9-11-28/h4-7,12-13,23H,8-11H2,1-3H3,(H-,26,29,30)
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n/an/a 9n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
Myristoyl-CoA:protein N-myristoyltransferase (Nmt)


(Homo sapiens (Human))
BDBM184985
PNG
(US9156811, DDD90091)
Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1ccc(cc1)-c1cccc(CC2CCN(C)CC2)c1
Show InChI InChI=1S/C26H34N4O2S/c1-19-26(20(2)29(4)27-19)30(5)33(31,32)25-11-9-23(10-12-25)24-8-6-7-22(18-24)17-21-13-15-28(3)16-14-21/h6-12,18,21H,13-17H2,1-5H3
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n/an/a 9n/an/an/an/an/an/a



Univeristy of Dundee

US Patent


Assay Description
Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...


US Patent US9156811 (2015)

More data for this
Ligand-Target Pair
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