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Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with Target = 'N-arachidonyl glycine receptor'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50072775
PNG
(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Show SMILES CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
Show InChI InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
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PubMed
n/an/a 5.99E+3n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398222
PNG
(CHEMBL2177264)
Show SMILES CCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3)c(=O)oc2c1
Show InChI InChI=1S/C25H30O3/c1-4-5-6-10-13-25(2,3)20-16-22(26)21-15-19(24(27)28-23(21)17-20)14-18-11-8-7-9-12-18/h7-9,11-12,15-17,26H,4-6,10,13-14H2,1-3H3
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n/an/a 8.10E+3n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50448075
PNG
(CHEMBL1258979)
Show SMILES CC(C)=C[C@H]1C[C@]2(C)[C@H](CC[C@@]3(C)[C@H]2CC[C@H]2Cc4c([nH]c5ccccc45)[C@]32C)O1
Show InChI InChI=1S/C28H37NO/c1-17(2)14-19-16-26(3)23-11-10-18-15-21-20-8-6-7-9-22(20)29-25(21)28(18,5)27(23,4)13-12-24(26)30-19/h6-9,14,18-19,23-24,29H,10-13,15-16H2,1-5H3/t18-,19-,23-,24-,26-,27-,28+/m0/s1
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n/an/a 9.91E+3n/an/an/an/an/an/a


TBA

Assay Description
Inverse agonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 7.5 uM THC-mediated beta-arrestin recruitment after 90 mins ...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434878
PNG
(CHEMBL2387536)
Show SMILES COc1c(C)c(C)c2oc(=O)c(Cc3ccc(F)cc3)cc2c1C
Show InChI InChI=1S/C20H19FO3/c1-11-12(2)19-17(13(3)18(11)23-4)10-15(20(22)24-19)9-14-5-7-16(21)8-6-14/h5-8,10H,9H2,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434879
PNG
(CHEMBL2387535)
Show SMILES Cc1c(C)c2oc(=O)c(Cc3ccccc3)cc2c(C)c1O
Show InChI InChI=1S/C19H18O3/c1-11-12(2)18-16(13(3)17(11)20)10-15(19(21)22-18)9-14-7-5-4-6-8-14/h4-8,10,20H,9H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434880
PNG
(CHEMBL2387533)
Show SMILES COc1ccccc1Cc1cc2c(C)c(OC)c(C)c(C)c2oc1=O
Show InChI InChI=1S/C21H22O4/c1-12-13(2)20-17(14(3)19(12)24-5)11-16(21(22)25-20)10-15-8-6-7-9-18(15)23-4/h6-9,11H,10H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434881
PNG
(CHEMBL2181545)
Show SMILES CCCCC1(CCCCC1)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C28H34O4/c1-4-5-13-28(14-9-6-10-15-28)22-18-25(31-3)23-17-21(27(29)32-26(23)19-22)16-20-11-7-8-12-24(20)30-2/h7-8,11-12,17-19H,4-6,9-10,13-16H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398217
PNG
(CHEMBL2181543)
Show SMILES CCCCC1(CCCC1)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C27H32O4/c1-4-5-12-27(13-8-9-14-27)21-17-24(30-3)22-16-20(26(28)31-25(22)18-21)15-19-10-6-7-11-23(19)29-2/h6-7,10-11,16-18H,4-5,8-9,12-15H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398219
PNG
(CHEMBL2181541)
Show SMILES CCCCCCCC(C)(C)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C28H36O4/c1-6-7-8-9-12-15-28(2,3)22-18-25(31-5)23-17-21(27(29)32-26(23)19-22)16-20-13-10-11-14-24(20)30-4/h10-11,13-14,17-19H,6-9,12,15-16H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434877
PNG
(CHEMBL2387538)
Show SMILES COc1c(C)c(C)c2oc(=O)c(Cc3ccccc3C)cc2c1C
Show InChI InChI=1S/C21H22O3/c1-12-8-6-7-9-16(12)10-17-11-18-15(4)19(23-5)13(2)14(3)20(18)24-21(17)22/h6-9,11H,10H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434876
PNG
(CHEMBL2387539)
Show SMILES Cc1ccccc1Cc1cc2c(C)c(O)c(C)c(C)c2oc1=O
Show InChI InChI=1S/C20H20O3/c1-11-7-5-6-8-15(11)9-16-10-17-14(4)18(21)12(2)13(3)19(17)23-20(16)22/h5-8,10,21H,9H2,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398237
PNG
(CHEMBL2177249)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3cccc(OC)c3)c(=O)oc2c1
Show InChI InChI=1S/C23H26O4/c1-4-5-6-8-17-13-21(26-3)20-15-18(23(24)27-22(20)14-17)11-16-9-7-10-19(12-16)25-2/h7,9-10,12-15H,4-6,8,11H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398229
PNG
(CHEMBL2177257)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C23H26O4/c1-4-5-6-9-16-12-21(26-3)19-15-18(23(24)27-22(19)13-16)14-17-10-7-8-11-20(17)25-2/h7-8,10-13,15H,4-6,9,14H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50448074
PNG
(EMINDOLE SB | Emindole Sb)
Show SMILES CC(C)=CCC[C@]1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C
Show InChI InChI=1S/C28H39NO/c1-18(2)9-8-15-26(3)23-13-12-19-17-21-20-10-6-7-11-22(20)29-25(21)28(19,5)27(23,4)16-14-24(26)30/h6-7,9-11,19,23-24,29-30H,8,12-17H2,1-5H3/t19-,23-,24-,26-,27-,28+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 10 uM THC-mediated beta-arrestin recruitment after 90 mins by bet...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50448073
PNG
(CHEMBL3120631)
Show SMILES CC(C)=CCC[C@]1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C34H49NO6/c1-19(2)9-8-15-32(3)25-13-12-20-17-22-21-10-6-7-11-23(21)35-30(22)34(20,5)33(25,4)16-14-26(32)41-31-29(39)28(38)27(37)24(18-36)40-31/h6-7,9-11,20,24-29,31,35-39H,8,12-18H2,1-5H3/t20-,24+,25-,26-,27+,28-,29-,31-,32-,33-,34+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 10 uM THC-mediated beta-arrestin recruitment after 90 mins by bet...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50278476
PNG
(5-Isopropyl-3,8-dimethylchromen-2-one | CHEMBL5067...)
Show SMILES CC(C)c1ccc(C)c2oc(=O)c(C)cc12
Show InChI InChI=1S/C14H16O2/c1-8(2)11-6-5-9(3)13-12(11)7-10(4)14(15)16-13/h5-8H,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50278475
PNG
(3-Benzyl-5-isopropyl-8-methylchromen-2-one | CHEMB...)
Show SMILES CC(C)c1ccc(C)c2oc(=O)c(Cc3ccccc3)cc12
Show InChI InChI=1S/C20H20O2/c1-13(2)17-10-9-14(3)19-18(17)12-16(20(21)22-19)11-15-7-5-4-6-8-15/h4-10,12-13H,11H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398212
PNG
(CHEMBL2181549)
Show SMILES CC(C)c1ccc(C)c2oc(=O)c(Cc3ccccc3O)cc12
Show InChI InChI=1S/C20H20O3/c1-12(2)16-9-8-13(3)19-17(16)11-15(20(22)23-19)10-14-6-4-5-7-18(14)21/h4-9,11-12,21H,10H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398221
PNG
(CHEMBL2181539)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c2cc(Cc3ccccc3OC)c(=O)oc2c1
Show InChI InChI=1S/C27H34O4/c1-6-7-8-11-14-27(2,3)21-17-24(30-5)22-16-20(26(28)31-25(22)18-21)15-19-12-9-10-13-23(19)29-4/h9-10,12-13,16-18H,6-8,11,14-15H2,1-5H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398223
PNG
(CHEMBL2177263)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c2cc(Cc3ccccc3)c(=O)oc2c1
Show InChI InChI=1S/C26H32O3/c1-5-6-7-11-14-26(2,3)21-17-23(28-4)22-16-20(25(27)29-24(22)18-21)15-19-12-9-8-10-13-19/h8-10,12-13,16-18H,5-7,11,14-15H2,1-4H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434882
PNG
(CHEMBL2387532)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccc(Br)cc3)c(=O)oc2c1
Show InChI InChI=1S/C22H23BrO3/c1-3-4-5-6-16-12-20(25-2)19-14-17(22(24)26-21(19)13-16)11-15-7-9-18(23)10-8-15/h7-10,12-14H,3-6,11H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434883
PNG
(CHEMBL2387530)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccc(Cl)cc3)c(=O)oc2c1
Show InChI InChI=1S/C22H23ClO3/c1-3-4-5-6-16-12-20(25-2)19-14-17(22(24)26-21(19)13-16)11-15-7-9-18(23)10-8-15/h7-10,12-14H,3-6,11H2,1-2H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398226
PNG
(CHEMBL2177260)
Show SMILES CCCCCc1cc(O)c2cc(Cc3ccccc3Cl)c(=O)oc2c1
Show InChI InChI=1S/C21H21ClO3/c1-2-3-4-7-14-10-19(23)17-13-16(21(24)25-20(17)11-14)12-15-8-5-6-9-18(15)22/h5-6,8-11,13,23H,2-4,7,12H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398227
PNG
(CHEMBL2177259)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccccc3Cl)c(=O)oc2c1
Show InChI InChI=1S/C22H23ClO3/c1-3-4-5-8-15-11-20(25-2)18-14-17(22(24)26-21(18)12-15)13-16-9-6-7-10-19(16)23/h6-7,9-12,14H,3-5,8,13H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398232
PNG
(CHEMBL2177254)
Show SMILES CCCCCc1cc(O)c2cc(Cc3ccccc3C)c(=O)oc2c1
Show InChI InChI=1S/C22H24O3/c1-3-4-5-9-16-11-20(23)19-14-18(22(24)25-21(19)12-16)13-17-10-7-6-8-15(17)2/h6-8,10-12,14,23H,3-5,9,13H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398233
PNG
(CHEMBL2177253)
Show SMILES CCCCCc1cc(OC)c2cc(Cc3ccccc3C)c(=O)oc2c1
Show InChI InChI=1S/C23H26O3/c1-4-5-6-10-17-12-21(25-3)20-15-19(23(24)26-22(20)13-17)14-18-11-8-7-9-16(18)2/h7-9,11-13,15H,4-6,10,14H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398236
PNG
(CHEMBL2177250)
Show SMILES CCCCCc1cc(O)c2cc(Cc3cccc(O)c3)c(=O)oc2c1
Show InChI InChI=1S/C21H22O4/c1-2-3-4-6-15-11-19(23)18-13-16(21(24)25-20(18)12-15)9-14-7-5-8-17(22)10-14/h5,7-8,10-13,22-23H,2-4,6,9H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50278379
PNG
(3-Benzyl-5-methoxy-7-methylchromen-2-one | CHEMBL4...)
Show SMILES COc1cc(C)cc2oc(=O)c(Cc3ccccc3)cc12
Show InChI InChI=1S/C18H16O3/c1-12-8-16(20-2)15-11-14(18(19)21-17(15)9-12)10-13-6-4-3-5-7-13/h3-9,11H,10H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398241
PNG
(CHEMBL2181551)
Show SMILES COc1cccc(Cc2cc3c(OC)cc(Br)cc3oc2=O)c1
Show InChI InChI=1S/C18H15BrO4/c1-21-14-5-3-4-11(7-14)6-12-8-15-16(22-2)9-13(19)10-17(15)23-18(12)20/h3-5,7-10H,6H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434885
PNG
(CHEMBL2387743)
Show SMILES COc1ccccc1Cc1cc2c(C)ccc(C)c2oc1=O
Show InChI InChI=1S/C19H18O3/c1-12-8-9-13(2)18-16(12)11-15(19(20)22-18)10-14-6-4-5-7-17(14)21-3/h4-9,11H,10H2,1-3H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 1.01E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50434884
PNG
(CHEMBL2387744)
Show SMILES COc1ccccc1Cc1cc2c(C)ccc(C(C)C)c2oc1=O
Show InChI InChI=1S/C21H22O3/c1-13(2)17-10-9-14(3)18-12-16(21(22)24-20(17)18)11-15-7-5-6-8-19(15)23-4/h5-10,12-13H,11H2,1-4H3
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n/an/a 1.13E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398218
PNG
(CHEMBL2181542)
Show SMILES CCCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3O)c(=O)oc2c1
Show InChI InChI=1S/C26H32O4/c1-4-5-6-7-10-13-26(2,3)20-16-23(28)21-15-19(25(29)30-24(21)17-20)14-18-11-8-9-12-22(18)27/h8-9,11-12,15-17,27-28H,4-7,10,13-14H2,1-3H3
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n/an/a 1.25E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50448076
PNG
(CHEMBL3120632)
Show SMILES COC(C)(C)\C=C\C[C@]1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1Cc3c([nH]c4ccccc34)[C@]21C
Show InChI InChI=1S/C29H41NO2/c1-26(2,32-6)15-9-16-27(3)23-13-12-19-18-21-20-10-7-8-11-22(20)30-25(21)29(19,5)28(23,4)17-14-24(27)31/h7-11,15,19,23-24,30-31H,12-14,16-18H2,1-6H3/b15-9+/t19-,23-,24-,27-,28-,29+/m0/s1
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n/an/a 1.34E+4n/an/an/an/an/an/a


TBA

Assay Description
Inverse agonist activity at human GPR18 expressed in CHO cells assessed as inhibition of 7.5 uM THC-mediated beta-arrestin recruitment after 90 mins ...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50398220
PNG
(CHEMBL2181540)
Show SMILES CCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3O)c(=O)oc2c1
Show InChI InChI=1S/C25H30O4/c1-4-5-6-9-12-25(2,3)19-15-22(27)20-14-18(24(28)29-23(20)16-19)13-17-10-7-8-11-21(17)26/h7-8,10-11,14-16,26-27H,4-6,9,12-13H2,1-3H3
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n/an/a 1.59E+4n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR18 transfected in CHO cells assessed as delta9-THC-induced beta-arrestin recruitment incubated 60 mins prior to delta...


Citation and Details
More data for this
Ligand-Target Pair
N-arachidonyl glycine receptor


(Homo sapiens)
BDBM50007391
PNG
((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Show SMILES CCCCCc1cc(O)c2[C@@H]3C=C(C)CC[C@H]3C(C)(C)Oc2c1
Show InChI InChI=1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1
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n/an/an/an/a 4.61E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Agonist activity at human GPR18 transfected in CHO cells after 90 mins by beta-arrestin translocation assay


Citation and Details
More data for this
Ligand-Target Pair