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Found 551 hits Enz. Inhib. hit(s) with Target = 'N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204883
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-(4-p-tolyloxy-pip...)
Show SMILES Cc1ccc(OC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)cc1
Show InChI InChI=1S/C20H21N3O4/c1-12-2-4-13(5-3-12)27-14-6-8-23(9-7-14)20(26)19-21-15-10-17(24)18(25)11-16(15)22-19/h2-5,10-11,14,24-25H,6-9H2,1H3,(H,21,22)
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n/an/a 1.10n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204865
PNG
(CHEMBL220611 | [4-(4-fluoro-benzyl)-piperidin-1-yl...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C20H20FN3O3/c21-14-3-1-12(2-4-14)9-13-5-7-24(8-6-13)20(27)19-22-15-10-17(25)18(26)11-16(15)23-19/h1-4,10-11,13,25-26H,5-9H2,(H,22,23)
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n/an/a 1.20n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204868
PNG
(CHEMBL424752 | N-[2-(4-benzyl-piperidin-1-carbonyl...)
Show SMILES CS(=O)(=O)Nc1cc2nc([nH]c2cc1NS(C)(=O)=O)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H27N5O5S2/c1-33(29,30)25-19-13-17-18(14-20(19)26-34(2,31)32)24-21(23-17)22(28)27-10-8-16(9-11-27)12-15-6-4-3-5-7-15/h3-7,13-14,16,25-26H,8-12H2,1-2H3,(H,23,24)
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n/an/a 1.30n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204882
PNG
(CHEMBL375615 | [4-(4-chloro-phenoxy)-piperidin-1-y...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(CC1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C19H18ClN3O4/c20-11-1-3-12(4-2-11)27-13-5-7-23(8-6-13)19(26)18-21-14-9-16(24)17(25)10-15(14)22-18/h1-4,9-10,13,24-25H,5-8H2,(H,21,22)
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n/an/a 1.70n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204899
PNG
((4-benzylpiperidine-1-yl)-[5(6)-hydroxy-1H-benzimi...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H21N3O3/c24-17-11-15-16(12-18(17)25)22-19(21-15)20(26)23-8-6-14(7-9-23)10-13-4-2-1-3-5-13/h1-5,11-12,14,24-25H,6-10H2,(H,21,22)
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n/an/a 2.20n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204887
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methyl-benz...)
Show SMILES Cc1cccc(CC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O3/c1-13-3-2-4-15(9-13)10-14-5-7-24(8-6-14)21(27)20-22-16-11-18(25)19(26)12-17(16)23-20/h2-4,9,11-12,14,25-26H,5-8,10H2,1H3,(H,22,23)
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n/an/a 2.40n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204861
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methoxy-ben...)
Show SMILES COc1cccc(CC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O4/c1-28-15-4-2-3-14(10-15)9-13-5-7-24(8-6-13)21(27)20-22-16-11-18(25)19(26)12-17(16)23-20/h2-4,10-13,25-26H,5-9H2,1H3,(H,22,23)
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n/an/a 2.5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204864
PNG
(CHEMBL220474 | [4-(4-fluoro-phenoxy)-piperidin-1-y...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(CC1)Oc1ccc(F)cc1
Show InChI InChI=1S/C19H18FN3O4/c20-11-1-3-12(4-2-11)27-13-5-7-23(8-6-13)19(26)18-21-14-9-16(24)17(25)10-15(14)22-18/h1-4,9-10,13,24-25H,5-8H2,(H,21,22)
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n/an/a 2.90n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204883
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-(4-p-tolyloxy-pip...)
Show SMILES Cc1ccc(OC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)cc1
Show InChI InChI=1S/C20H21N3O4/c1-12-2-4-13(5-3-12)27-14-6-8-23(9-7-14)20(26)19-21-15-10-17(24)18(25)11-16(15)22-19/h2-5,10-11,14,24-25H,6-9H2,1H3,(H,21,22)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189380
PNG
(CHEMBL215372 | N-(2-(4-benzylpiperidine-1-carbonyl...)
Show SMILES CS(=O)(=O)Nc1ccc2nc([nH]c2c1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H24N4O3S/c1-29(27,28)24-17-7-8-18-19(14-17)23-20(22-18)21(26)25-11-9-16(10-12-25)13-15-5-3-2-4-6-15/h2-8,14,16,24H,9-13H2,1H3,(H,22,23)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189391
PNG
((5-hydroxy-1H-benzo[d]imidazol-2-yl)(4-(p-tolyloxy...)
Show SMILES Cc1ccc(OC2CCN(CC2)C(=O)c2nc3ccc(O)cc3[nH]2)cc1
Show InChI InChI=1S/C20H21N3O3/c1-13-2-5-15(6-3-13)26-16-8-10-23(11-9-16)20(25)19-21-17-7-4-14(24)12-18(17)22-19/h2-7,12,16,24H,8-11H2,1H3,(H,21,22)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204863
PNG
((4-benzyl-piperidin-1-yl)-[4(7)-hydroxy-1H-benzimi...)
Show SMILES Oc1ccc(O)c2[nH]c(nc12)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H21N3O3/c24-15-6-7-16(25)18-17(15)21-19(22-18)20(26)23-10-8-14(9-11-23)12-13-4-2-1-3-5-13/h1-7,14,24-25H,8-12H2,(H,21,22)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204861
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methoxy-ben...)
Show SMILES COc1cccc(CC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O4/c1-28-15-4-2-3-14(10-15)9-13-5-7-24(8-6-13)21(27)20-22-16-11-18(25)19(26)12-17(16)23-20/h2-4,10-13,25-26H,5-9H2,1H3,(H,22,23)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204868
PNG
(CHEMBL424752 | N-[2-(4-benzyl-piperidin-1-carbonyl...)
Show SMILES CS(=O)(=O)Nc1cc2nc([nH]c2cc1NS(C)(=O)=O)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H27N5O5S2/c1-33(29,30)25-19-13-17-18(14-20(19)26-34(2,31)32)24-21(23-17)22(28)27-10-8-16(9-11-27)12-15-6-4-3-5-7-15/h3-7,13-14,16,25-26H,8-12H2,1-2H3,(H,23,24)
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n/an/a 3n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189383
PNG
((4-(3-methoxybenzyl)piperidin-1-yl)(5-hydroxy-1H-b...)
Show SMILES COc1cccc(CC2CCN(CC2)C(=O)c2nc3ccc(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O3/c1-27-17-4-2-3-15(12-17)11-14-7-9-24(10-8-14)21(26)20-22-18-6-5-16(25)13-19(18)23-20/h2-6,12-14,25H,7-11H2,1H3,(H,22,23)
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n/an/a 3.20n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204862
PNG
(CHEMBL436521 | N-(2-((4-benzylpiperidin-1-yl)methy...)
Show SMILES CS(=O)(=O)Nc1ccc2nc(CN3CCC(Cc4ccccc4)CC3)[nH]c2c1
Show InChI InChI=1S/C21H26N4O2S/c1-28(26,27)24-18-7-8-19-20(14-18)23-21(22-19)15-25-11-9-17(10-12-25)13-16-5-3-2-4-6-16/h2-8,14,17,24H,9-13,15H2,1H3,(H,22,23)
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n/an/a 3.5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204862
PNG
(CHEMBL436521 | N-(2-((4-benzylpiperidin-1-yl)methy...)
Show SMILES CS(=O)(=O)Nc1ccc2nc(CN3CCC(Cc4ccccc4)CC3)[nH]c2c1
Show InChI InChI=1S/C21H26N4O2S/c1-28(26,27)24-18-7-8-19-20(14-18)23-21(22-19)15-25-11-9-17(10-12-25)13-16-5-3-2-4-6-16/h2-8,14,17,24H,9-13,15H2,1H3,(H,22,23)
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n/an/a 3.5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50241126
PNG
((4-benzylpiperidin-1-yl)(5-hydroxy-1H-benzo[d]imid...)
Show SMILES Oc1ccc2nc([nH]c2c1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H21N3O2/c24-16-6-7-17-18(13-16)22-19(21-17)20(25)23-10-8-15(9-11-23)12-14-4-2-1-3-5-14/h1-7,13,15,24H,8-12H2,(H,21,22)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204865
PNG
(CHEMBL220611 | [4-(4-fluoro-benzyl)-piperidin-1-yl...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C20H20FN3O3/c21-14-3-1-12(2-4-14)9-13-5-7-24(8-6-13)20(27)19-22-15-10-17(25)18(26)11-16(15)23-19/h1-4,10-11,13,25-26H,5-9H2,(H,22,23)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204899
PNG
((4-benzylpiperidine-1-yl)-[5(6)-hydroxy-1H-benzimi...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H21N3O3/c24-17-11-15-16(12-18(17)25)22-19(21-15)20(26)23-8-6-14(7-9-23)10-13-4-2-1-3-5-13/h1-5,11-12,14,24-25H,6-10H2,(H,21,22)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204884
PNG
(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Show SMILES Fc1ccc(CC2CCN(CCS(=O)c3ccc4[nH]c(=O)oc4c3)CC2)cc1
Show InChI InChI=1S/C21H23FN2O3S/c22-17-3-1-15(2-4-17)13-16-7-9-24(10-8-16)11-12-28(26)18-5-6-19-20(14-18)27-21(25)23-19/h1-6,14,16H,7-13H2,(H,23,25)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204884
PNG
(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Show SMILES Fc1ccc(CC2CCN(CCS(=O)c3ccc4[nH]c(=O)oc4c3)CC2)cc1
Show InChI InChI=1S/C21H23FN2O3S/c22-17-3-1-15(2-4-17)13-16-7-9-24(10-8-16)11-12-28(26)18-5-6-19-20(14-18)27-21(25)23-19/h1-6,14,16H,7-13H2,(H,23,25)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189385
PNG
((4-(4-fluorobenzyl)piperidin-1-yl)(5-hydroxy-1H-be...)
Show SMILES Oc1ccc2nc([nH]c2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C20H20FN3O2/c21-15-3-1-13(2-4-15)11-14-7-9-24(10-8-14)20(26)19-22-17-6-5-16(25)12-18(17)23-19/h1-6,12,14,25H,7-11H2,(H,22,23)
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n/an/a 4n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204895
PNG
((4-amino-1H-indol-2-yl)-(4-benzyl-piperidin-1-yl)-...)
Show SMILES Nc1cccc2[nH]c(cc12)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H23N3O/c22-18-7-4-8-19-17(18)14-20(23-19)21(25)24-11-9-16(10-12-24)13-15-5-2-1-3-6-15/h1-8,14,16,23H,9-13,22H2
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n/an/a 4.30n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50241129
PNG
((5-hydroxy-1H-benzoimidazol-2-yl)-[4-(4-methyl-ben...)
Show SMILES Cc1ccc(CC2CCN(CC2)C(=O)c2nc3ccc(O)cc3[nH]2)cc1
Show InChI InChI=1S/C21H23N3O2/c1-14-2-4-15(5-3-14)12-16-8-10-24(11-9-16)21(26)20-22-18-7-6-17(25)13-19(18)23-20/h2-7,13,16,25H,8-12H2,1H3,(H,22,23)
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n/an/a 4.40n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220586
PNG
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Show SMILES OC(CN1CCC(O)(CC1)c1cccc(F)c1)c1ccc2NC(=O)CCc2c1
Show InChI InChI=1S/C22H25FN2O3/c23-18-3-1-2-17(13-18)22(28)8-10-25(11-9-22)14-20(26)16-4-6-19-15(12-16)5-7-21(27)24-19/h1-4,6,12-13,20,26,28H,5,7-11,14H2,(H,24,27)
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n/an/a 4.5n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204873
PNG
((4-benzylpiperidin-1-yl)-(3,6-dihydro-pirrolo[3,2-...)
Show SMILES O=C(N1CCC(Cc2ccccc2)CC1)c1cc2c(ccc3[nH]ncc23)[nH]1
Show InChI InChI=1S/C22H22N4O/c27-22(21-13-17-18-14-23-25-20(18)7-6-19(17)24-21)26-10-8-16(9-11-26)12-15-4-2-1-3-5-15/h1-7,13-14,16,24H,8-12H2,(H,23,25)
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n/an/a 5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50241127
PNG
((5-hydroxy-1H-benzoimidazol-2-yl)-[4-(3-methyl-ben...)
Show SMILES Cc1cccc(CC2CCN(CC2)C(=O)c2nc3ccc(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O2/c1-14-3-2-4-16(11-14)12-15-7-9-24(10-8-15)21(26)20-22-18-6-5-17(25)13-19(18)23-20/h2-6,11,13,15,25H,7-10,12H2,1H3,(H,22,23)
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n/an/a 5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204887
PNG
((6-hydroxy-1H-benzimidazol-2-yl)-[4-(3-methyl-benz...)
Show SMILES Cc1cccc(CC2CCN(CC2)C(=O)c2nc3cc(O)c(O)cc3[nH]2)c1
Show InChI InChI=1S/C21H23N3O3/c1-13-3-2-4-15(9-13)10-14-5-7-24(8-6-14)21(27)20-22-16-11-18(25)19(26)12-17(16)23-20/h2-4,9,11-12,14,25-26H,5-8,10H2,1H3,(H,22,23)
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n/an/a 5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50241128
PNG
((4-(3-fluorobenzyl)piperidin-1-yl)(5-hydroxy-1H-be...)
Show SMILES Oc1ccc2nc([nH]c2c1)C(=O)N1CCC(Cc2cccc(F)c2)CC1
Show InChI InChI=1S/C20H20FN3O2/c21-15-3-1-2-14(11-15)10-13-6-8-24(9-7-13)20(26)19-22-17-5-4-16(25)12-18(17)23-19/h1-5,11-13,25H,6-10H2,(H,22,23)
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n/an/a 5.20n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50445988
PNG
(CHEMBL3103124)
Show SMILES Oc1cc2[nH]cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c2cc1O
Show InChI InChI=1S/C22H24N2O3/c25-20-11-17-18(13-23-19(17)12-21(20)26)22(27)14-24-8-6-16(7-9-24)10-15-4-2-1-3-5-15/h1-5,11-13,16,23,25-26H,6-10,14H2
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n/an/a 5.5n/an/an/an/an/an/a



Universit£ di Messina

Curated by ChEMBL


Assay Description
Displacement of [3H]Ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortex


Bioorg Med Chem 22: 1040-8 (2014)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220573
PNG
(1-(1-(3-chloro-4-hydroxyphenyl)-1-hydroxypropan-2-...)
Show SMILES CC(C(O)c1ccc(O)c(Cl)c1)N1CCC(O)(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C20H23ClFNO3/c1-13(19(25)14-2-7-18(24)17(21)12-14)23-10-8-20(26,9-11-23)15-3-5-16(22)6-4-15/h2-7,12-13,19,24-26H,8-11H2,1H3
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n/an/a 5.60n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204891
PNG
((4-benzylpiperidin-1-yl)-(3,6-dihydro-imidazo[4,5-...)
Show SMILES O=C(N1CCC(Cc2ccccc2)CC1)c1cc2c(ccc3[nH]cnc23)[nH]1
Show InChI InChI=1S/C22H22N4O/c27-22(20-13-17-18(25-20)6-7-19-21(17)24-14-23-19)26-10-8-16(9-11-26)12-15-4-2-1-3-5-15/h1-7,13-14,16,25H,8-12H2,(H,23,24)
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50080029
PNG
(4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...)
Show SMILES C[C@@H](CN1CCC(Cc2ccccc2)CC1)[C@@H](O)c1ccc(O)cc1
Show InChI InChI=1S/C22H29NO2/c1-17(22(25)20-7-9-21(24)10-8-20)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18/h2-10,17,19,22,24-25H,11-16H2,1H3/t17-,22+/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189388
PNG
((4-(4-fluorophenoxy)piperidin-1-yl)(5-hydroxy-1H-b...)
Show SMILES Oc1ccc2nc([nH]c2c1)C(=O)N1CCC(CC1)Oc1ccc(F)cc1
Show InChI InChI=1S/C19H18FN3O3/c20-12-1-4-14(5-2-12)26-15-7-9-23(10-8-15)19(25)18-21-16-6-3-13(24)11-17(16)22-18/h1-6,11,15,24H,7-10H2,(H,21,22)
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204864
PNG
(CHEMBL220474 | [4-(4-fluoro-phenoxy)-piperidin-1-y...)
Show SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(CC1)Oc1ccc(F)cc1
Show InChI InChI=1S/C19H18FN3O4/c20-11-1-3-12(4-2-11)27-13-5-7-23(8-6-13)19(26)18-21-14-9-16(24)17(25)10-15(14)22-18/h1-4,9-10,13,24-25H,5-8H2,(H,21,22)
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50080029
PNG
(4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...)
Show SMILES C[C@@H](CN1CCC(Cc2ccccc2)CC1)[C@@H](O)c1ccc(O)cc1
Show InChI InChI=1S/C22H29NO2/c1-17(22(25)20-7-9-21(24)10-8-20)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18/h2-10,17,19,22,24-25H,11-16H2,1H3/t17-,22+/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50134652
PNG
((4-Benzyl-piperidin-1-yl)-(4,6-dihydroxy-1H-indol-...)
Show SMILES Oc1cc(O)c2cc([nH]c2c1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H22N2O3/c24-16-11-18-17(20(25)12-16)13-19(22-18)21(26)23-8-6-15(7-9-23)10-14-4-2-1-3-5-14/h1-5,11-13,15,22,24-25H,6-10H2
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n/an/a 6n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220589
PNG
(6-(1-hydroxy-2-(4-hydroxy-4-(3-(phenoxymethyl)phen...)
Show SMILES CC(C(O)c1ccc2NC(=O)CCc2c1)N1CCC(O)(CC1)c1cccc(COc2ccccc2)c1
Show InChI InChI=1S/C30H34N2O4/c1-21(29(34)24-10-12-27-23(19-24)11-13-28(33)31-27)32-16-14-30(35,15-17-32)25-7-5-6-22(18-25)20-36-26-8-3-2-4-9-26/h2-10,12,18-19,21,29,34-35H,11,13-17,20H2,1H3,(H,31,33)
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n/an/a 6.30n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50134652
PNG
((4-Benzyl-piperidin-1-yl)-(4,6-dihydroxy-1H-indol-...)
Show SMILES Oc1cc(O)c2cc([nH]c2c1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H22N2O3/c24-16-11-18-17(20(25)12-16)13-19(22-18)21(26)23-8-6-15(7-9-23)10-14-4-2-1-3-5-14/h1-5,11-13,15,22,24-25H,6-10H2
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n/an/a 6.5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204884
PNG
(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Show SMILES Fc1ccc(CC2CCN(CCS(=O)c3ccc4[nH]c(=O)oc4c3)CC2)cc1
Show InChI InChI=1S/C21H23FN2O3S/c22-17-3-1-15(2-4-17)13-16-7-9-24(10-8-16)11-12-28(26)18-5-6-19-20(14-18)27-21(25)23-19/h1-6,14,16H,7-13H2,(H,23,25)
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n/an/a 6.60n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220583
PNG
(6-(2-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-...)
Show SMILES CC(C(O)c1ccc2NC(=O)CCc2c1)N1CCC(O)(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H27ClN2O3/c1-15(22(28)17-2-8-20-16(14-17)3-9-21(27)25-20)26-12-10-23(29,11-13-26)18-4-6-19(24)7-5-18/h2,4-8,14-15,22,28-29H,3,9-13H2,1H3,(H,25,27)
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n/an/a 6.60n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220586
PNG
(1-[2-hydroxy-2-(6-hydroxy-biphenyl-3-yl)-1-methyl-...)
Show SMILES OC(CN1CCC(O)(CC1)c1cccc(F)c1)c1ccc2NC(=O)CCc2c1
Show InChI InChI=1S/C22H25FN2O3/c23-18-3-1-2-17(13-18)22(28)8-10-25(11-9-22)14-20(26)16-4-6-19-15(12-16)5-7-21(27)24-19/h1-4,6,12-13,20,26,28H,5,7-11,14H2,(H,24,27)
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n/an/a 6.80n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50134648
PNG
((6-Hydroxy-1H-indol-2-yl)-(4-phenoxymethyl-piperid...)
Show SMILES Oc1ccc2cc([nH]c2c1)C(=O)N1CCC(COc2ccccc2)CC1
Show InChI InChI=1S/C21H22N2O3/c24-17-7-6-16-12-20(22-19(16)13-17)21(25)23-10-8-15(9-11-23)14-26-18-4-2-1-3-5-18/h1-7,12-13,15,22,24H,8-11,14H2
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n/an/a 7n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50032651
PNG
(1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-y...)
Show SMILES C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(O)(CC1)c1ccccc1
Show InChI InChI=1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1
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n/an/a 7n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220588
PNG
(6-(1-hydroxy-2-(4-hydroxy-4-(3-methoxyphenyl)piper...)
Show SMILES COc1cccc(c1)C1(O)CCN(CC1)C(C)C(O)c1ccc2NC(=O)CCc2c1
Show InChI InChI=1S/C24H30N2O4/c1-16(23(28)18-6-8-21-17(14-18)7-9-22(27)25-21)26-12-10-24(29,11-13-26)19-4-3-5-20(15-19)30-2/h3-6,8,14-16,23,28-29H,7,9-13H2,1-2H3,(H,25,27)
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n/an/a 8.30n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50189384
PNG
((5-hydroxy-1H-benzoimidazol-2-yl)-[4-(2-methyl-ben...)
Show SMILES Cc1ccccc1CC1CCN(CC1)C(=O)c1nc2ccc(O)cc2[nH]1
Show InChI InChI=1S/C21H23N3O2/c1-14-4-2-3-5-16(14)12-15-8-10-24(11-9-15)21(26)20-22-18-7-6-17(25)13-19(18)23-20/h2-7,13,15,25H,8-12H2,1H3,(H,22,23)
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n/an/a 8.40n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane


Bioorg Med Chem Lett 16: 4638-40 (2006)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204870
PNG
(2-[(4-benzyl-piperidin-1-yl)-imino-methyl]-1H-indo...)
Show SMILES Oc1ccc2cc([nH]c2c1)C(=N)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H23N3O/c22-21(20-13-17-6-7-18(25)14-19(17)23-20)24-10-8-16(9-11-24)12-15-4-2-1-3-5-15/h1-7,13-14,16,22-23,25H,8-12H2
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n/an/a 8.5n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50204862
PNG
(CHEMBL436521 | N-(2-((4-benzylpiperidin-1-yl)methy...)
Show SMILES CS(=O)(=O)Nc1ccc2nc(CN3CCC(Cc4ccccc4)CC3)[nH]c2c1
Show InChI InChI=1S/C21H26N4O2S/c1-28(26,27)24-18-7-8-19-20(14-18)23-21(22-19)15-25-11-9-17(10-12-25)13-16-5-3-2-4-6-16/h2-8,14,17,24H,9-13,15H2,1H3,(H,22,23)
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n/an/a 8.60n/an/an/an/an/an/a



Gedeon Richter Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...


J Med Chem 50: 901-14 (2007)

More data for this
Ligand-Target Pair
N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B)


(Rattus norvegicus (Rat))
BDBM50220581
PNG
(7-(2-(4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Show SMILES CC(C(O)c1ccc2NC(=O)COc2c1)N1CCC(O)(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C22H25FN2O4/c1-14(21(27)15-2-7-18-19(12-15)29-13-20(26)24-18)25-10-8-22(28,9-11-25)16-3-5-17(23)6-4-16/h2-7,12,14,21,27-28H,8-11,13H2,1H3,(H,24,26)
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n/an/a 8.70n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane


Bioorg Med Chem Lett 17: 5558-62 (2007)

More data for this
Ligand-Target Pair
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