Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439141![]() (CHEMBL2418481) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439146![]() (CHEMBL2418529) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439147![]() (CHEMBL2418524) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439140![]() (CHEMBL2418487) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439143![]() (CHEMBL2418504) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439142![]() (CHEMBL2418505) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439144![]() (CHEMBL2418502) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439152![]() (CHEMBL2418568) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439139![]() (CHEMBL2418489) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439150![]() (CHEMBL2418545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439151![]() (CHEMBL2418569) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439138![]() (CHEMBL2418558) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars AffyNet ![]() | PDB Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439149![]() (CHEMBL2418548) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439148![]() (CHEMBL2418551) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50439145![]() (CHEMBL2418514) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrop... | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427257![]() (CHEMBL2325118) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427257![]() (CHEMBL2325118) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometr... | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427255![]() (CHEMBL2325114) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometr... | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427256![]() (CHEMBL2325402) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometr... | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427254![]() (CHEMBL2325133) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometr... | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427253![]() (CHEMBL2325124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 3.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometr... | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427257![]() (CHEMBL2325118) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology& Science-Pilani Curated by ChEMBL | Assay Description Competitive inhibition of Mycobacterium tuberculosis CysK1 | Bioorg Med Chem Lett 23: 1182-6 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
O-acetylserine sulfhydrylase (Mycobacterium tuberculosis) | BDBM50427257![]() (CHEMBL2325118) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Karolinska Institutet Curated by ChEMBL | Assay Description Competitive inhibition of Mycobacterium tuberculosis CysK1 | J Med Chem 56: 6457-66 (2013) | |||||||||||
More data for this Ligand-Target Pair |