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Compile Data Set for Download or QSAR

Found 17 hits Enz. Inhib. hit(s) with Target = 'Peptide N-myristoyltransferase 2'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50364113
PNG
(CHEMBL1230468)
Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1
Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3
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n/an/a 3n/an/an/an/an/an/a



University of Dundee

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384914
PNG
(CHEMBL2036496 | CHEMBL2079453)
Show SMILES CCCCc1c(C)nc2ccc(OC)cc2c1SCCC#N
Show InChI InChI=1S/C18H22N2OS/c1-4-5-7-15-13(2)20-17-9-8-14(21-3)12-16(17)18(15)22-11-6-10-19/h8-9,12H,4-7,11H2,1-3H3
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1.14E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384911
PNG
(CHEMBL2036500)
Show SMILES CCc1c(C)nc2ccc(OC)cc2c1SCCC#N
Show InChI InChI=1S/C16H18N2OS/c1-4-13-11(2)18-15-7-6-12(19-3)10-14(15)16(13)20-9-5-8-17/h6-7,10H,4-5,9H2,1-3H3
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2.32E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384923
PNG
(CHEMBL2036636)
Show SMILES CCOC(=O)c1cnc2ccc(F)cc2c1SCCC#N
Show InChI InChI=1S/C15H13FN2O2S/c1-2-20-15(19)12-9-18-13-5-4-10(16)8-11(13)14(12)21-7-3-6-17/h4-5,8-9H,2-3,7H2,1H3
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3.75E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384916
PNG
(CHEMBL2036504)
Show SMILES CCOC(=O)c1c(C)nc2ccccc2c1SCCC#N
Show InChI InChI=1S/C16H16N2O2S/c1-3-20-16(19)14-11(2)18-13-8-5-4-7-12(13)15(14)21-10-6-9-17/h4-5,7-8H,3,6,10H2,1-2H3
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4.15E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384920
PNG
(CHEMBL2036508)
Show SMILES CCCCc1c(C)nc2ccc(OC)cc2c1SCCCC#N
Show InChI InChI=1S/C19H24N2OS/c1-4-5-8-16-14(2)21-18-10-9-15(22-3)13-17(18)19(16)23-12-7-6-11-20/h9-10,13H,4-8,12H2,1-3H3
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4.61E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384917
PNG
(CHEMBL2036505)
Show SMILES CCOC(=O)c1c(CC)nc2ccccc2c1SCCC#N
Show InChI InChI=1S/C17H18N2O2S/c1-3-13-15(17(20)21-4-2)16(22-11-7-10-18)12-8-5-6-9-14(12)19-13/h5-6,8-9H,3-4,7,11H2,1-2H3
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9.42E+4n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384924
PNG
(CHEMBL2036637)
Show SMILES CCOC(=O)c1cnc2ccc(C)cc2c1SCCC#N
Show InChI InChI=1S/C16H16N2O2S/c1-3-20-16(19)13-10-18-14-6-5-11(2)9-12(14)15(13)21-8-4-7-17/h5-6,9-10H,3-4,8H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384925
PNG
(CHEMBL2036638)
Show SMILES CCOC(=O)c1cnc2ccc(Cl)cc2c1SCCC#N
Show InChI InChI=1S/C15H13ClN2O2S/c1-2-20-15(19)12-9-18-13-5-4-10(16)8-11(13)14(12)21-7-3-6-17/h4-5,8-9H,2-3,7H2,1H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM33749
PNG
(3-(6-Bromo-3-butyl-2-methyl-quinolin-4-ylsulfanyl)...)
Show SMILES CCCCc1c(C)nc2ccc(Br)cc2c1SCCC#N
Show InChI InChI=1S/C17H19BrN2S/c1-3-4-6-14-12(2)20-16-8-7-13(18)11-15(16)17(14)21-10-5-9-19/h7-8,11H,3-6,10H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384922
PNG
(CHEMBL1339047)
Show SMILES CCCCc1c(C)nc2ccccc2c1SCCC#N
Show InChI InChI=1S/C17H20N2S/c1-3-4-8-14-13(2)19-16-10-6-5-9-15(16)17(14)20-12-7-11-18/h5-6,9-10H,3-4,7-8,12H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384921
PNG
(CHEMBL2036510)
Show SMILES CCCCc1c(C)nc2ccc(OC)cc2c1SCCCO
Show InChI InChI=1S/C18H25NO2S/c1-4-5-7-15-13(2)19-17-9-8-14(21-3)12-16(17)18(15)22-11-6-10-20/h8-9,12,20H,4-7,10-11H2,1-3H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384918
PNG
(CHEMBL2036506)
Show SMILES CCCc1nc2ccccc2c(SCCC#N)c1C(=O)OCC
Show InChI InChI=1S/C18H20N2O2S/c1-3-8-15-16(18(21)22-4-2)17(23-12-7-11-19)13-9-5-6-10-14(13)20-15/h5-6,9-10H,3-4,7-8,12H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384915
PNG
(CHEMBL2036503)
Show SMILES CCOC(=O)c1cnc2ccccc2c1SCCC#N
Show InChI InChI=1S/C15H14N2O2S/c1-2-19-15(18)12-10-17-13-7-4-3-6-11(13)14(12)20-9-5-8-16/h3-4,6-7,10H,2,5,9H2,1H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384912
PNG
(CHEMBL2036502)
Show SMILES CCOC(=O)c1cnc2ccc(OC)cc2c1SCCC#N
Show InChI InChI=1S/C16H16N2O3S/c1-3-21-16(19)13-10-18-14-6-5-11(20-2)9-12(14)15(13)22-8-4-7-17/h5-6,9-10H,3-4,8H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384913
PNG
(CHEMBL2036501)
Show SMILES COc1ccc2nc(C)cc(SCCC#N)c2c1
Show InChI InChI=1S/C14H14N2OS/c1-10-8-14(18-7-3-6-15)12-9-11(17-2)4-5-13(12)16-10/h4-5,8-9H,3,7H2,1-2H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair
Peptide N-myristoyltransferase 2


(Homo sapiens)
BDBM50384919
PNG
(CHEMBL2036507)
Show SMILES CCCCc1c(C)nc2ccc(OC)cc2c1SCCC#C
Show InChI InChI=1S/C19H23NOS/c1-5-7-9-16-14(3)20-18-11-10-15(21-4)13-17(18)19(16)22-12-8-6-2/h2,10-11,13H,5,7-9,12H2,1,3-4H3
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>1.00E+5n/an/an/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of human N-myristoyltransferase 2 using human pp60Src92-16 amino acids) as substrate


Citation and Details
More data for this
Ligand-Target Pair